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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

BOLA3 Gene

protein-coding   GIFtS: 46
GCID: GC02M074275

BolA Family Member 3

(Previous names: bolA-like 3 (E. coli), bolA homolog 3 (E. coli))
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
BolA Family Member 31 2
BolA Homolog 3 (E. Coli)1
BolA-Like 3 (E. Coli)1
MMDS22
BolA Homolog 32
BolA-Like Protein 32

External Ids:    HGNC: 244151   Entrez Gene: 3889622   Ensembl: ENSG000001631707   OMIM: 6131835   UniProtKB: Q53S333   

Export aliases for BOLA3 gene to outside databases

Previous GC identifers: GC02M074216 GC02M074098


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for BOLA3 Gene:
This gene encodes a protein that plays an essential role in the production of iron-sulfur (Fe-S) clusters for the
normal maturation of lipoate-containing 2-oxoacid dehydrogenases, and for the assembly of the mitochondrial
respiratory chain complexes. Mutation in this gene has been associated with multiple mitochondrial dysfunctions
syndrome-2. Two alternatively spliced transcript variants encoding different isoforms with distinct subcellular
localization have been reported for this gene (PMID:21944046). (provided by RefSeq, Dec 2011)

GeneCards Summary for BOLA3 Gene: 
BOLA3 (bolA family member 3) is a protein-coding gene. Diseases associated with BOLA3 include multiple mitochondrial dysfunctions syndrome 2, and lactic acidosis. GO annotations related to this gene include molecular_function.




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000002.11  NC_018913.2  NT_022184.15  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the BOLA3 gene promoter:
         TBP   STAT1   p53   POU3F1   STAT1beta   STAT1alpha   RORalpha1   IRF-2   TFIID   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidBOLA3 promoter sequence
   Search SABiosciences Chromatin IP Primers for BOLA3

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat BOLA3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2p13.1   Ensembl cytogenetic band:  2p13.1   HGNC cytogenetic band: 2p13.1

BOLA3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
BOLA3 gene location

GeneLoc information about chromosome 2         GeneLoc Exon Structure

GeneLoc location for GC02M074275:  view genomic region     (about GC identifiers)

Start:
74,362,525 bp from pter      End:
74,375,121 bp from pter
Size:
12,597 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: BOLA3_HUMAN, Q53S33 (See protein sequence)
Recommended Name: BolA-like protein 3  
Size: 107 amino acids; 12114 Da
Subcellular location: Secreted. Note=Could be secreted via a non-classical export pathway
Secondary accessions: G3XAB0
Alternative splicing: 2 isoforms:  Q53S33-1   Q53S33-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for BOLA3: NX_Q53S33

Explore proteomics data for BOLA3 at MOPED 

BOLA3 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

BOLA3 Protein Expression

REFSEQ proteins (2 alternative transcripts): 
NP_001030582.1  NP_997717.2  

ENSEMBL proteins: 
 ENSP00000331369   ENSP00000295326  

Human Recombinant Protein Products for BOLA3: 
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Cloud-Clone Corp. Proteins for BOLA3 

Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005575cellular_component ND--
GO:0005576extracellular region IEA--

BOLA3 for ontologies           About GeneDecksing



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Cloud-Clone Corp. CLIAs for BOLA3


(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section
1 InterPro protein domain:
 IPR002634 BolA

Graphical View of Domain Structure for InterPro Entry Q53S33

ProtoNet protein and cluster: Q53S33

1 Blocks protein domain: IPB002634 BolA-like protein

UniProtKB/Swiss-Prot: BOLA3_HUMAN, Q53S33
Similarity: Belongs to the bolA/yrbA family


BOLA3 for domains           About GeneDecksing


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
About This Section

     Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0003674molecular_function ND--
     
BOLA3 for ontologies           About GeneDecksing


Phenotypes:
     1 GenomeRNAi human phenotype for BOLA3:
 Increased circadian period len 

Animal Models:
   inGenious Targeting Laboratory - Custom generated mouse model solutions for BOLA3 
   inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for BOLA3

   genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for BOLA3 
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miRNA
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hsa-miR-374b hsa-miR-3121-3p hsa-miR-374a
SwitchGear 3'UTR luciferase reporter plasmidBOLA3 3' UTR sequence
Inhib. RNA
Products:
    
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Gene Editing
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Clone
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In Situ Assay
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Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for BOLA3


(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
About This Section



Interactions:

    Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for BOLA3

STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

2 Interacting proteins for BOLA3 (ENSP000003313694) via UniProtKB, MINT, STRING, and/or I2D
InteractantInteraction Details
GeneCardExternal ID(s)
GLRX3ENSP000003308364STRING: ENSP00000330836
GLRX5ENSP000003285704STRING: ENSP00000328570
About this table

Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0008150biological_process ND--

BOLA3 for ontologies           About GeneDecksing



(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section
Browse Small Molecules at EMD Millipore
Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for BOLA3

Search CenterWatch for drugs/clinical trials and news about BOLA3

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for BOLA3 gene (2 alternative transcripts): 
NM_001035505.1  NM_212552.2  

Unigene Cluster for BOLA3:

BolA homolog 3 (E. coli)
Hs.61472  [show with all ESTs]
Unigene Representative Sequence: CD357422
5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000327428(uc002skc.1 uc002skd.1) ENST00000477685 ENST00000484655
ENST00000295326 ENST00000469676
miRNA
Products:
     
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat BOLA3
3 QIAGEN miScript miRNA Assays for microRNAs that regulate BOLA3:
hsa-miR-374b hsa-miR-3121-3p hsa-miR-374a
SwitchGear 3'UTR luciferase reporter plasmidBOLA3 3' UTR sequence
Inhib. RNA
Products:
     
Browse for Gene Knock-down Tools from EMD Millipore
OriGene RNAi products in human, mouse, rat for BOLA3
QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat BOLA3
Clone
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OriGene clones in human, mouse for BOLA3 (see all 10)
OriGene ORF clones in mouse, rat for BOLA3
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript: all cDNA clones in your preferred vector (see all 2): BOLA3 (NM_212552)
DNA2.0 Custom Codon Optimized Gene Synthesis Service for BOLA3
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat BOLA3
Sirion Biotech Customized lentivirus for stable overexpression of BOLA3 
                     Customized lentivirus expression plasmids for stable overexpression of BOLA3 
Primer
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OriGene qPCR primer pairs and template standards for BOLA3
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  QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat BOLA3
  QIAGEN QuantiFast Probe-based Assays in human, mouse, rat BOLA3

Additional mRNA sequence: 

BC017744.2 BC028282.1 BC042036.1 DQ225187.1 

6 DOTS entries:

DT.101966960  DT.100024316  DT.100758437  DT.91818202  DT.75103685  DT.95264257 

24/89 AceView cDNA sequences (see all 89):

BF001216 AW301192 AA636041 BE466764 AI335537 AI470601 AA625548 AI878836 
AW299794 AI436769 AW001812 BM785747 AI419586 BM834895 CD679328 AI658822 
AI439173 BX111938 AW301212 BE504229 AI380704 BC042036 AA603060 AI767924 

GeneLoc Exon Structure


(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

BOLA3 expression in normal human tissues (normalized intensities)      BOLA3 embryonic expression: see
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: GATTGCGGAT
BOLA3 Expression
About this image


BOLA3 expression in embryonic tissues and stem cells    About this table
Data from LifeMap, the Embryonic Development and Stem Cells Database 
 5/3 selected tissues (see all 3) fully expand
 
 Endothelium (Cardiovascular System)
         blood vessel   
 
 Adipose (Muscoskeletal System)
         Thoracic Perivascular Adipose
 
 Kidney (Urinary System)

See BOLA3 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for BOLA3

SOURCE GeneReport for Unigene cluster: Hs.61472

UniProtKB/Swiss-Prot: BOLA3_HUMAN, Q53S33
Tissue specificity: Widely expressed

    SABiosciences Custom PCR Arrays for BOLA3
Primer
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QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat BOLA3
QIAGEN QuantiFast Probe-based Assays in human, mouse, rat BOLA3
In Situ
Assay Products:
 

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for BOLA3

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of animals and fungi.

Orthologs for BOLA3 gene from 6/12 species (see all 12)    About this table
Organism Taxonomic
classification
Gene Description Human
Similarity
Orthology
Type
Details
mouse
(Mus musculus)
Mammalia Bola31 , 5 bolA-like 3 (E. coli)1, 5 85.22(n)1
92.45(a)1
  6 (35.94 cM)5
786531  NM_175277.41  NP_780486.11 
 833491475 
lizard
(Anolis carolinensis)
Reptilia BOLA36
Uncharacterized protein
68(a)
1 ↔ 1
GL343968.1(88864-91232)
African clawed frog
(Xenopus laevis)
Amphibia Xl.220672 Xenopus laevis transcribed sequence with weak similarity more 72.3(n)    BG345425.1 
zebrafish
(Danio rerio)
Actinopterygii Dr.171922 Transcribed sequence with weak similarity to protein more 74.62(n)    BM104158.1 
worm
(Caenorhabditis elegans)
Secernentea Y105E8A.116
Protein Y105E8A.11
33(a)
1 ↔ 1
I(14432791-14433747)
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes AIM1(YAL046C)4 Protein involved in mitochondrial function or organization; more   --   1(57385-57029) 851251  NP_009353.1 


ENSEMBL Gene Tree for BOLA3 (if available)
TreeFam Gene Tree for BOLA3 (if available)

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
Paralogs for BOLA3 gene

BOLA3 for paralogs           About GeneDecksing


4 Pseudogenes.org Pseudogenes for BOLA3
PGOHUM00000242881 PGOHUM00000234484 PGOHUM00000235385 PGOHUM00000236431


(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

10/369 SNPs in BOLA3 are shown (see all 369)    About this table     
Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 2 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
rs778393831,2
C,F--74099372(+) TTTTTT/GTTTTT 2 -- int13Minor allele frequency- G:0.19WA CSA 122
rs412859831,2
C,F--74233289(+) TCCTCG/AGTGTG 2 -- ds50016Minor allele frequency- A:0.08NA WA CSA 246
rs412859811,2
C,F--74233294(+) GGTGTG/CACTTG 2 -- ds50015Minor allele frequency- C:0.14NA WA CSA 126
rs1172098121,2
F--74233314(+) TCAGGG/ACAGGT 2 -- ds50011Minor allele frequency- A:0.02EA 120
rs344363601,2
C,F--74233318(+) GGCAGG/TTCCAT 2 -- ds50015Minor allele frequency- T:0.22NA WA 130
rs8288791,2
C,F,A,H--74233345(+) GGAATG/ATCTGC 2 -- ds500129Minor allele frequency- A:0.03NA EA NS WA CSA 2119
rs1397891301,2
--74233350(+) ATCTGC/TCTGTG 2 -- ds50010--------
rs1169478251,2
C,F--74233373(+) GGGAGG/ACAGGG 2 -- ds50011Minor allele frequency- A:0.02EA 120
rs1499183171,2
--74233429(+) CCTACC/GAAGAA 2 -- ds50010--------
rs1167855391,2
F--74233473(+) GAACCC/TGGATC 2 -- ds50011Minor allele frequency- T:0.03WA 118

HapMap Linkage Disequilibrium report for BOLA3 (74362525 - 74375121 bp)

Structural Variations
     Database of Genomic Variants (DGV) 2 variations for BOLA3:    About this table     
Variant IDTypeSubtypePubMed ID
nsv874286CNV Loss21882294
nsv525117CNV Loss19592680


Human Gene Mutation Database (HGMD): BOLA3
SABiosciences Cancer Mutation PCR Assays
SeqTarget long-range PCR primers for resequencing BOLA3
DNA2.0 Custom Variant and Variant Library Synthesis for BOLA3

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section
OMIM gene information: 613183    OMIM disorders: --

UniProtKB/Swiss-Prot: BOLA3_HUMAN, Q53S33
  • Multiple mitochondrial dysfunctions syndrome 2 (MMDS2) [MIM:614299]: A severe disorder of systemic energy
    metabolism, resulting in weakness, respiratory failure, lack of neurologic development, lactic acidosis,
    hyperglycinemia and early death. Some patients show failure to thrive, pulmonary hypertension, hypotonia and
    irritability. Biochemical features include severe combined deficiency of the 2-oxoacid dehydrogenases, defective
    lipoic acid synthesis and reduction in activity of mitochondrial respiratory chain complexes. Note=The disease is
    caused by mutations affecting the gene represented in this entry

  • 5 diseases for BOLA3:    About MalaCards
    multiple mitochondrial dysfunctions syndrome 2    lactic acidosis    respiratory failure    hypotonia
    hypertension


    BOLA3 for disorders           About GeneDecksing

    Genetic Association Database (GAD): BOLA3
    Human Genome Epidemiology (HuGE) Navigator: BOLA3 (1 document)

    Export disorders for BOLA3 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for BOLA3 gene integrated from 9 sources:
    (articles sorted by number of sources associating them with BOLA3)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Mutations in iron-sulfur cluster scaffold genes NFU1 and BOLA3 cause a fatal deficiency of multiple respiratory chain and 2-oxoacid dehydrogenase enzymes. (PubMed id 21944046)1, 2 Cameron J.M.... Robinson B.H. (2011)
    2. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (2010)
    3. hBolA, novel non-classical secreted proteins, belonging to different BolA family with functional divergence. (PubMed id 18548201)1, 2 Zhou Y.B.... Han Z.G. (2008)
    4. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PubMed id 15815621)1, 2 Hillier L.W....Wilson R.K. (2005)
    5. Solution structure of a BolA-like protein from Mus musculus. (PubMed id 14718656)1, 3 Kasai T....Yokoyama S. (2004)
    6. Homozygous missense mutation in BOLA3 causes multiple mitochondrial dysfunctions syndrome in two siblings. (PubMed id 22562699)1 Haack T.B....Prokisch H. (2013)
    7. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
    8. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
    9. Hepatitis C virus core protein interacts with 14-3-3 protein and activates the kinase Raf-1. (PubMed id )2 Aoki H.... Hino O. (2000)
    10. Initial assessment of human gene diversity and expression patterns based upon 83 million nucleotides of cDNA sequence. (PubMed id 7566098)2 Adams M.D....White O. (1995)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 388962 HGNC: 24415 AceView: LOC388962 Ensembl:ENSG00000163170 euGenes: HUgn388962
    ECgene: BOLA3 H-InvDB: BOLA3

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for BOLA3 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for BOLA3 gene:
    Search GeneIP for patents involving BOLA3

    GeneCards and IP:
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    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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