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Aliases for BOLA2B Gene

Aliases for BOLA2B Gene

  • BolA Family Member 2B 2 3
  • BolA-Like Protein 2 Member B 3
  • BolA Homolog 2B (E. Coli) 2
  • BolA-Like 2B (E. Coli) 2
  • BolA-Like Protein 2B 3
  • BolA-Like Protein 2 3
  • BolA Homolog 2B 3
  • BolA-Like 2B 3
  • BOLA2 BOLA2B 4
  • BOLA2A 4
  • BOLA2 3

External Ids for BOLA2B Gene

Summaries for BOLA2B Gene

Entrez Gene Summary for BOLA2B Gene

  • This gene is located within a region of a segmental duplication on chromosome 16p. The product of this gene belongs to the eukaryotic subfamily of the BolA-like proteins. This gene encodes the BolA-like protein 2. The BolA-like proteins are widely conserved from prokaryotes to eukaryotes, and these proteins seem to be involved in cell proliferation or cell-cycle regulation. This duplicated region contains a complete copy of the short splice variant of the BOLA2 gene and a partial copy of the long splice variant of the BOLA2 gene. [provided by RefSeq, Jul 2008]

GeneCards Summary for BOLA2B Gene

BOLA2B (BolA Family Member 2B) is a Protein Coding gene. An important paralog of this gene is BOLA2.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for BOLA2B Gene

Genomics for BOLA2B Gene

Genomic Location for BOLA2B Gene

Start:
30,192,934 bp from pter
End:
30,194,306 bp from pter
Size:
1,373 bases
Orientation:
Minus strand

Genomic View for BOLA2B Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for BOLA2B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for BOLA2B Gene

Regulatory Elements for BOLA2B Gene

Proteins for BOLA2B Gene

  • Protein details for BOLA2B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9H3K6-BOLA2_HUMAN
    Recommended name:
    BolA-like protein 2
    Protein Accession:
    Q9H3K6
    Secondary Accessions:
    • A1L454
    • A7YDY3

    Protein attributes for BOLA2B Gene

    Size:
    86 amino acids
    Molecular mass:
    10117 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAH22832.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=AAI30402.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=AAI30404.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=AAI37533.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=AAI37535.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=AAI44689.1; Type=Erroneous initiation; Evidence={ECO:0000305};

    Alternative splice isoforms for BOLA2B Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for BOLA2B Gene

Proteomics data for BOLA2B Gene at MOPED

Post-translational modifications for BOLA2B Gene

  • Modification sites at PhosphoSitePlus
  • Ubiquitination at Lys43 and Lys73

Other Protein References for BOLA2B Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for BOLA2B Gene

Domains for BOLA2B Gene

Protein Domains for BOLA2B Gene

InterPro:
Blocks:
ProtoNet:

Suggested Antigen Peptide Sequences for BOLA2B Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q9H3K6

UniProtKB/Swiss-Prot:

BOLA2_HUMAN
Family:
  • Belongs to the BolA/IbaG family.:
    • Q9H3K6
genes like me logo Genes that share domains with BOLA2B: view

No data available for Gene Families for BOLA2B Gene

Function for BOLA2B Gene

miRNA for BOLA2B Gene

miRTarBase miRNAs that target BOLA2B

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for BOLA2B Gene

Localization for BOLA2B Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for BOLA2B Gene COMPARTMENTS Subcellular localization image for BOLA2B gene
Compartment Confidence
cytosol 2
extracellular 2
golgi apparatus 1
mitochondrion 1
nucleus 1

Gene Ontology (GO) - Cellular Components for BOLA2B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0070062 extracellular exosome IDA 23376485
genes like me logo Genes that share ontologies with BOLA2B: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for BOLA2B Gene

Pathways for BOLA2B Gene

SuperPathways for BOLA2B Gene

No Data Available

Interacting Proteins for BOLA2B Gene

Gene Ontology (GO) - Biological Process for BOLA2B Gene

None

No data available for Pathways by source for BOLA2B Gene

Transcripts for BOLA2B Gene

mRNA/cDNA for BOLA2B Gene

(1) REFSEQ mRNAs :
(4) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for BOLA2B Gene

No ASD Table

Relevant External Links for BOLA2B Gene

GeneLoc Exon Structure for
BOLA2B
ECgene alternative splicing isoforms for
BOLA2B

Expression for BOLA2B Gene

mRNA expression in normal human tissues for BOLA2B Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for BOLA2B Gene

SOURCE GeneReport for Unigene cluster for BOLA2B Gene Hs.647333

genes like me logo Genes that share expressions with BOLA2B: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for BOLA2B Gene

Orthologs for BOLA2B Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for BOLA2B Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia -- 36
  • 97 (a)
OneToMany
cow
(Bos Taurus)
Mammalia -- 36
  • 90 (a)
OneToMany
mouse
(Mus musculus)
Mammalia Bola2 36
  • 87 (a)
OneToMany
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 84 (a)
OneToMany
rat
(Rattus norvegicus)
Mammalia LOC100363408 35
  • 85.27 (n)
  • 81.4 (a)
zebrafish
(Danio rerio)
Actinopterygii BOLA2B 36
  • 58 (a)
OneToMany
fruit fly
(Drosophila melanogaster)
Insecta CG33672 36
  • 47 (a)
OneToMany
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes FRA2 38
Species with no ortholog for BOLA2B:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for BOLA2B Gene

ENSEMBL:
Gene Tree for BOLA2B (if available)
TreeFam:
Gene Tree for BOLA2B (if available)

Paralogs for BOLA2B Gene

Paralogs for BOLA2B Gene

Selected SIMAP similar genes for BOLA2B Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with BOLA2B: view

Variants for BOLA2B Gene

Structural Variations from Database of Genomic Variants (DGV) for BOLA2B Gene

Variant ID Type Subtype PubMed ID
dgv845e1 CNV Complex 17122850
nsv905711 CNV Gain 21882294
esv29892 CNV Gain 19812545
esv2714183 CNV Deletion 23290073
nsv498862 CNV Loss 21111241
nsv820959 CNV Duplication 20802225
nsv9426 CNV Gain 18304495
nsv905720 CNV Loss 21882294
dgv846e1 CNV Complex 17122850
dgv847e1 CNV Complex 17122850
nsv905723 CNV Loss 21882294
nsv9431 CNV Gain+Loss 18304495
esv22245 CNV Gain 19812545
nsv821543 CNV Duplication 20802225
nsv471387 CNV Duplication 19718026
nsv471388 CNV Duplication 19718026

Relevant External Links for BOLA2B Gene

HapMap Linkage Disequilibrium report
BOLA2B

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations from dbSNP and Humsavar for BOLA2B Gene

Disorders for BOLA2B Gene

No disorders were found for BOLA2B Gene.

No data available for UniProtKB/Swiss-Prot for BOLA2B Gene

Publications for BOLA2B Gene

  1. Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides. (PMID: 12665801) Gevaert K. … Vandekerckhove J. (Nat. Biotechnol. 2003) 3 4
  2. Solution structure of a BolA-like protein from Mus musculus. (PMID: 14718656) Kasai T. … Yokoyama S. (Protein Sci. 2004) 2 3
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  4. Functional specialization of beta-arrestin interactions revealed by proteomic analysis. (PMID: 17620599) Xiao K. … Lefkowitz R.J. (Proc. Natl. Acad. Sci. U.S.A. 2007) 3
  5. Dynamics of cullin-RING ubiquitin ligase network revealed by systematic quantitative proteomics. (PMID: 21145461) Bennett E.J. … Harper J.W. (Cell 2010) 3

Products for BOLA2B Gene

Sources for BOLA2B Gene

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