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Aliases for BOLA2 Gene

Aliases for BOLA2 Gene

  • BolA Family Member 2 2 3
  • BOLA2A 3 4
  • BolA-Like Protein 2 Member A 3
  • BolA Homolog 2 (E. Coli) 2
  • BolA-Like 2 (E. Coli) 2
  • BolA-Like Protein 2 3
  • BolA Homolog 2 3
  • BOLA2 BOLA2B 4
  • BolA-Like 2 3
  • My016 3

External Ids for BOLA2 Gene

Summaries for BOLA2 Gene

Entrez Gene Summary for BOLA2 Gene

  • This gene is located within a region of a segmental duplication on chromosome 16p. The product of this gene belongs to the eukaryotic subfamily of the BolA-like proteins. This gene encodes the BolA-like protein 2. The BolA-like proteins are widely conserved from prokaryotes to eukaryotes, and these proteins seem to be involved in cell proliferation or cell-cycle regulation. [provided by RefSeq, Jul 2008]

GeneCards Summary for BOLA2 Gene

BOLA2 (BolA Family Member 2) is a Protein Coding gene. An important paralog of this gene is BOLA2B.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for BOLA2 Gene

Genomics for BOLA2 Gene

Genomic Location for BOLA2 Gene

29,453,593 bp from pter
29,454,964 bp from pter
1,372 bases
Minus strand

Genomic View for BOLA2 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for BOLA2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for BOLA2 Gene

Regulatory Elements for BOLA2 Gene

Proteins for BOLA2 Gene

  • Protein details for BOLA2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    BolA-like protein 2
    Protein Accession:
    Secondary Accessions:
    • A1L454
    • A7YDY3

    Protein attributes for BOLA2 Gene

    86 amino acids
    Molecular mass:
    10117 Da
    Quaternary structure:
    No Data Available
    • Sequence=AAH22832.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=AAI30402.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=AAI30404.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=AAI37533.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=AAI37535.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=AAI44689.1; Type=Erroneous initiation; Evidence={ECO:0000305};

    Alternative splice isoforms for BOLA2 Gene


neXtProt entry for BOLA2 Gene

Proteomics data for BOLA2 Gene at MOPED

Post-translational modifications for BOLA2 Gene

  • Modification sites at PhosphoSitePlus
  • Ubiquitination at Lys43 and Lys73

Other Protein References for BOLA2 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for BOLA2 Gene

Domains for BOLA2 Gene

Protein Domains for BOLA2 Gene



  • Belongs to the BolA/IbaG family.:
    • Q9H3K6
genes like me logo Genes that share domains with BOLA2: view

No data available for Gene Families for BOLA2 Gene

Function for BOLA2 Gene

miRNA for BOLA2 Gene

miRTarBase miRNAs that target BOLA2

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for BOLA2 Gene

Localization for BOLA2 Gene

Subcellular locations from

Jensen Localization Image for BOLA2 Gene COMPARTMENTS Subcellular localization image for BOLA2 gene
Compartment Confidence
cytosol 2
extracellular 2
golgi apparatus 1
mitochondrion 1
nucleus 1

Gene Ontology (GO) - Cellular Components for BOLA2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0070062 extracellular exosome --
genes like me logo Genes that share ontologies with BOLA2: view

Pathways for BOLA2 Gene

SuperPathways for BOLA2 Gene

No Data Available

Interacting Proteins for BOLA2 Gene

Gene Ontology (GO) - Biological Process for BOLA2 Gene


No data available for Pathways by source for BOLA2 Gene

Transcripts for BOLA2 Gene

mRNA/cDNA for BOLA2 Gene

(6) REFSEQ mRNAs :
(12) Additional mRNA sequences :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for BOLA2 Gene

BolA homolog 2 (E. coli):
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for BOLA2 Gene

No ASD Table

Relevant External Links for BOLA2 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for BOLA2 Gene

mRNA expression in normal human tissues for BOLA2 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for BOLA2 Gene

SOURCE GeneReport for Unigene cluster for BOLA2 Gene Hs.444600

genes like me logo Genes that share expressions with BOLA2: view

Orthologs for BOLA2 Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for BOLA2 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia -- 37
  • 97 (a)
(Bos Taurus)
Mammalia -- 37
  • 90 (a)
(Mus musculus)
Mammalia Bola2 16
Bola2 37
  • 87 (a)
(Monodelphis domestica)
Mammalia -- 37
  • 84 (a)
(Rattus norvegicus)
Mammalia LOC100363408 36
  • 85.27 (n)
  • 81.4 (a)
(Danio rerio)
Actinopterygii BOLA2B 37
  • 58 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG33672 37
  • 47 (a)
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes FRA2 39
Species with no ortholog for BOLA2:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for BOLA2 Gene

Gene Tree for BOLA2 (if available)
Gene Tree for BOLA2 (if available)

Paralogs for BOLA2 Gene

Paralogs for BOLA2 Gene

Selected SIMAP similar genes for BOLA2 Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with BOLA2: view

Variants for BOLA2 Gene

Structural Variations from Database of Genomic Variants (DGV) for BOLA2 Gene

Variant ID Type Subtype PubMed ID
dgv845e1 CNV Complex 17122850
nsv905711 CNV Gain 21882294
esv29892 CNV Gain 19812545
esv2714183 CNV Deletion 23290073
nsv498862 CNV Loss 21111241
nsv820959 CNV Duplication 20802225
nsv9426 CNV Gain 18304495
nsv905720 CNV Loss 21882294
dgv846e1 CNV Complex 17122850
dgv847e1 CNV Complex 17122850
nsv905723 CNV Loss 21882294
nsv9431 CNV Gain+Loss 18304495
esv22245 CNV Gain 19812545
nsv821543 CNV Duplication 20802225
nsv471387 CNV Duplication 19718026
nsv471388 CNV Duplication 19718026

Relevant External Links for BOLA2 Gene

HapMap Linkage Disequilibrium report

No data available for Sequence variations from dbSNP and Humsavar for BOLA2 Gene

Disorders for BOLA2 Gene

No disorders were found for BOLA2 Gene.

No data available for UniProtKB/Swiss-Prot for BOLA2 Gene

Publications for BOLA2 Gene

  1. Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides. (PMID: 12665801) Gevaert K. … Vandekerckhove J. (Nat. Biotechnol. 2003) 3 4
  2. Solution structure of a BolA-like protein from Mus musculus. (PMID: 14718656) Kasai T. … Yokoyama S. (Protein Sci. 2004) 2 3
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  4. Functional specialization of beta-arrestin interactions revealed by proteomic analysis. (PMID: 17620599) Xiao K. … Lefkowitz R.J. (Proc. Natl. Acad. Sci. U.S.A. 2007) 3
  5. hBolA, novel non-classical secreted proteins, belonging to different BolA family with functional divergence. (PMID: 18548201) Zhou Y.B. … Han Z.G. (Mol. Cell. Biochem. 2008) 3

Products for BOLA2 Gene

Sources for BOLA2 Gene

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