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Aliases for BOLA1 Gene

Aliases for BOLA1 Gene

  • BolA Family Member 1 2 3
  • BolA Homolog 1 (E. Coli) 2
  • BolA-Like 1 (E. Coli) 2
  • BolA-Like Protein 1 3
  • BolA Homolog 1 3
  • BolA-Like 1 3
  • CGI-143 3
  • HBolA 4

External Ids for BOLA1 Gene

Previous GeneCards Identifiers for BOLA1 Gene

  • GC01P146685
  • GC01P148126
  • GC01P149859
  • GC01P121251

Summaries for BOLA1 Gene

GeneCards Summary for BOLA1 Gene

BOLA1 (BolA Family Member 1) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for BOLA1 Gene

Genomics for BOLA1 Gene

Regulatory Elements for BOLA1 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for BOLA1 Gene

Start:
149,887,890 bp from pter
End:
149,900,798 bp from pter
Size:
12,909 bases
Orientation:
Plus strand

Genomic View for BOLA1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for BOLA1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for BOLA1 Gene

Proteins for BOLA1 Gene

  • Protein details for BOLA1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9Y3E2-BOLA1_HUMAN
    Recommended name:
    BolA-like protein 1
    Protein Accession:
    Q9Y3E2
    Secondary Accessions:
    • B2R7K2
    • D3DUZ4
    • Q5QNY0

    Protein attributes for BOLA1 Gene

    Size:
    137 amino acids
    Molecular mass:
    14289 Da
    Quaternary structure:
    No Data Available

neXtProt entry for BOLA1 Gene

Proteomics data for BOLA1 Gene at MOPED

Post-translational modifications for BOLA1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for BOLA1 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for BOLA1 Gene

Domains for BOLA1 Gene

Protein Domains for BOLA1 Gene

InterPro:
Blocks:
ProtoNet:

Suggested Antigen Peptide Sequences for BOLA1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q9Y3E2

UniProtKB/Swiss-Prot:

BOLA1_HUMAN :
  • Q9Y3E2
Family:
  • Belongs to the BolA/IbaG family.
genes like me logo Genes that share domains with BOLA1: view

No data available for Gene Families for BOLA1 Gene

Function for BOLA1 Gene

Gene Ontology (GO) - Molecular Function for BOLA1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with BOLA1: view

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for BOLA1

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for BOLA1 Gene

Localization for BOLA1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for BOLA1 Gene

Secreted. Note=Could be secreted via a non-classical export pathway.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for BOLA1 Gene COMPARTMENTS Subcellular localization image for BOLA1 gene
Compartment Confidence
extracellular 5
mitochondrion 2
cytosol 1
golgi apparatus 1
nucleus 1
peroxisome 1

Gene Ontology (GO) - Cellular Components for BOLA1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005576 extracellular region IEA --
GO:0005739 mitochondrion IEA --
genes like me logo Genes that share ontologies with BOLA1: view

Pathways for BOLA1 Gene

SuperPathways for BOLA1 Gene

No Data Available

Gene Ontology (GO) - Biological Process for BOLA1 Gene

None

No data available for Pathways by source for BOLA1 Gene

Transcripts for BOLA1 Gene

mRNA/cDNA for BOLA1 Gene

Unigene Clusters for BOLA1 Gene

BolA homolog 1 (E. coli):
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for BOLA1

Primer Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for BOLA1 Gene

ExUns: 1a · 1b · 1c ^ 2a · 2b · 2c · 2d · 2e
SP1: -
SP2: - -
SP3:

Relevant External Links for BOLA1 Gene

GeneLoc Exon Structure for
BOLA1
ECgene alternative splicing isoforms for
BOLA1

Expression for BOLA1 Gene

mRNA expression in normal human tissues for BOLA1 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for BOLA1 Gene

SOURCE GeneReport for Unigene cluster for BOLA1 Gene Hs.13880

mRNA Expression by UniProt/SwissProt for BOLA1 Gene

Q9Y3E2-BOLA1_HUMAN
Tissue specificity: Widely expressed.
genes like me logo Genes that share expressions with BOLA1: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA differential expression in normal tissues for BOLA1 Gene

Orthologs for BOLA1 Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for BOLA1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia BOLA1 35
  • 99.76 (n)
  • 99.27 (a)
BOLA1 36
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia BOLA1 35
  • 84.46 (n)
  • 86.47 (a)
BOLA1 36
  • 85 (a)
OneToOne
dog
(Canis familiaris)
Mammalia BOLA1 35
  • 83.45 (n)
  • 84.67 (a)
BOLA1 36
  • 85 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Bola1 35
  • 80.64 (n)
  • 81.62 (a)
Bola1 16
Bola1 36
  • 81 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Bola1 35
  • 80.15 (n)
  • 82.35 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia bola1 35
  • 57.43 (n)
  • 62.38 (a)
zebrafish
(Danio rerio)
Actinopterygii bola1 35
  • 63.04 (n)
  • 64.36 (a)
bola1 36
  • 53 (a)
OneToOne
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP003706 35
  • 49.16 (n)
  • 54.55 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG31126 35
  • 49.39 (n)
  • 48.18 (a)
CG31126 36
  • 36 (a)
OneToOne
worm
(Caenorhabditis elegans)
Secernentea K11H12.1 35
  • 50.17 (n)
  • 49.49 (a)
K11H12.1 36
  • 46 (a)
OneToOne
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes -- 36
  • 32 (a)
OneToOne
-- 38
-- 38
Species with no ortholog for BOLA1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for BOLA1 Gene

ENSEMBL:
Gene Tree for BOLA1 (if available)
TreeFam:
Gene Tree for BOLA1 (if available)

Paralogs for BOLA1 Gene

No data available for Paralogs for BOLA1 Gene

Variants for BOLA1 Gene

Sequence variations from dbSNP and Humsavar for BOLA1 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type MAF
rs11011 -- 149,900,607(-) GGAGA(G/T)TATGT utr-variant-3-prime
rs1044808 - 149,900,352(+) GCTGG(C/G)AGGTC missense, reference
rs1349532 -- 149,899,450(+) CATTG(C/T)TGGGT upstream-variant-2KB
rs1355237 -- 149,899,725(-) TTGTG(A/G)TTGGG intron-variant, utr-variant-5-prime
rs1376675 -- 149,899,449(+) GCATT(A/G)CTGGG upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for BOLA1 Gene

Variant ID Type Subtype PubMed ID
dgv117e1 CNV Complex 17122850
nsv428235 CNV Gain 18775914
esv2750807 CNV Gain 17911159
dgv123e1 CNV Complex 17122850
dgv125e1 CNV Complex 17122850
nsv831525 CNV Gain 17160897
essv23032 CNV CNV 17122850
nsv831537 CNV Loss 17160897

Relevant External Links for BOLA1 Gene

HapMap Linkage Disequilibrium report
BOLA1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for BOLA1 Gene

Disorders for BOLA1 Gene

Relevant External Links for BOLA1

Genetic Association Database (GAD)
BOLA1
Human Genome Epidemiology (HuGE) Navigator
BOLA1
genes like me logo Genes that share disorders with BOLA1: view

No data available for UniProtKB/Swiss-Prot for BOLA1 Gene

Publications for BOLA1 Gene

  1. Solution structure of a BolA-like protein from Mus musculus. (PMID: 14718656) Kasai T. … Yokoyama S. (Protein Sci. 2004) 2 3
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 3 4
  4. hBolA, novel non-classical secreted proteins, belonging to different BolA family with functional divergence. (PMID: 18548201) Zhou Y.B. … Han Z.G. (Mol. Cell. Biochem. 2008) 3 4
  5. Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. (PMID: 20877624) Hendrickson S.L. … O'Brien S.J. (PLoS ONE 2010) 3 48

Products for BOLA1 Gene

Sources for BOLA1 Gene

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