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Aliases for BOLA1 Gene

Aliases for BOLA1 Gene

  • BolA Family Member 1 2 3 5
  • BolA Homolog 1 (E. Coli) 2
  • BolA-Like 1 (E. Coli) 2
  • BolA Homolog 1 3
  • BolA-Like 1 3
  • CGI-143 3
  • HBolA 4

External Ids for BOLA1 Gene

Previous GeneCards Identifiers for BOLA1 Gene

  • GC01P146685
  • GC01P148126
  • GC01P149859
  • GC01P121251

Summaries for BOLA1 Gene

GeneCards Summary for BOLA1 Gene

BOLA1 (BolA Family Member 1) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for BOLA1 Gene

Genomics for BOLA1 Gene

Regulatory Elements for BOLA1 Gene

Enhancers for BOLA1 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around BOLA1 on UCSC Golden Path with GeneCards custom track

Genomic Location for BOLA1 Gene

149,887,890 bp from pter
149,900,798 bp from pter
12,909 bases
Plus strand

Genomic View for BOLA1 Gene

Genes around BOLA1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
BOLA1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for BOLA1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for BOLA1 Gene

Proteins for BOLA1 Gene

  • Protein details for BOLA1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    BolA-like protein 1
    Protein Accession:
    Secondary Accessions:
    • B2R7K2
    • D3DUZ4
    • Q5QNY0

    Protein attributes for BOLA1 Gene

    137 amino acids
    Molecular mass:
    14289 Da
    Quaternary structure:
    No Data Available

neXtProt entry for BOLA1 Gene

Proteomics data for BOLA1 Gene at MOPED

Post-translational modifications for BOLA1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for BOLA1 Gene

No data available for DME Specific Peptides for BOLA1 Gene

Domains & Families for BOLA1 Gene

Protein Domains for BOLA1 Gene


Suggested Antigen Peptide Sequences for BOLA1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the BolA/IbaG family.
  • Belongs to the BolA/IbaG family.
genes like me logo Genes that share domains with BOLA1: view

No data available for Gene Families for BOLA1 Gene

Function for BOLA1 Gene

genes like me logo Genes that share phenotypes with BOLA1: view

Animal Model Products

miRNA for BOLA1 Gene

miRTarBase miRNAs that target BOLA1

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for BOLA1 Gene

Localization for BOLA1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for BOLA1 Gene

Secreted. Note=Could be secreted via a non-classical export pathway.

Subcellular locations from

Jensen Localization Image for BOLA1 Gene COMPARTMENTS Subcellular localization image for BOLA1 gene
Compartment Confidence
extracellular 3
cytosol 2
nucleus 2
golgi apparatus 1
mitochondrion 1
peroxisome 1

Gene Ontology (GO) - Cellular Components for BOLA1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005739 mitochondrion IEA --
genes like me logo Genes that share ontologies with BOLA1: view

Pathways & Interactions for BOLA1 Gene

SuperPathways for BOLA1 Gene

No Data Available

Gene Ontology (GO) - Biological Process for BOLA1 Gene


No data available for Pathways by source and SIGNOR curated interactions for BOLA1 Gene

Drugs & Compounds for BOLA1 Gene

No Compound Related Data Available

Transcripts for BOLA1 Gene

Unigene Clusters for BOLA1 Gene

BolA homolog 1 (E. coli):
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for BOLA1 Gene

ExUns: 1a · 1b · 1c ^ 2a · 2b · 2c · 2d · 2e
SP1: -
SP2: - -

Relevant External Links for BOLA1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for BOLA1 Gene

mRNA expression in normal human tissues for BOLA1 Gene

Protein differential expression in normal tissues from HIPED for BOLA1 Gene

This gene is overexpressed in Uterus (10.7), Peripheral blood mononuclear cells (7.2), Adrenal (7.2), and Skin (7.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MOPED, and MaxQB for BOLA1 Gene

SOURCE GeneReport for Unigene cluster for BOLA1 Gene Hs.13880

mRNA Expression by UniProt/SwissProt for BOLA1 Gene

Tissue specificity: Widely expressed.
genes like me logo Genes that share expression patterns with BOLA1: view

Protein tissue co-expression partners for BOLA1 Gene

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA differential expression in normal tissues for BOLA1 Gene

Orthologs for BOLA1 Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for BOLA1 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia BOLA1 35
  • 84.46 (n)
  • 86.47 (a)
BOLA1 36
  • 85 (a)
(Canis familiaris)
Mammalia BOLA1 35
  • 83.45 (n)
  • 84.67 (a)
BOLA1 36
  • 85 (a)
(Mus musculus)
Mammalia Bola1 35
  • 80.64 (n)
  • 81.62 (a)
Bola1 16
Bola1 36
  • 81 (a)
(Pan troglodytes)
Mammalia BOLA1 35
  • 99.76 (n)
  • 99.27 (a)
BOLA1 36
  • 99 (a)
(Rattus norvegicus)
Mammalia Bola1 35
  • 80.15 (n)
  • 82.35 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia bola1 35
  • 57.43 (n)
  • 62.38 (a)
(Danio rerio)
Actinopterygii bola1 35
  • 63.04 (n)
  • 64.36 (a)
bola1 36
  • 53 (a)
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP003706 35
  • 49.16 (n)
  • 54.55 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG31126 35
  • 49.39 (n)
  • 48.18 (a)
CG31126 36
  • 36 (a)
(Caenorhabditis elegans)
Secernentea K11H12.1 35
  • 50.17 (n)
  • 49.49 (a)
K11H12.1 36
  • 46 (a)
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes -- 36
  • 32 (a)
-- 38
-- 38
Species with no ortholog for BOLA1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for BOLA1 Gene

Gene Tree for BOLA1 (if available)
Gene Tree for BOLA1 (if available)

Paralogs for BOLA1 Gene

No data available for Paralogs for BOLA1 Gene

Variants for BOLA1 Gene

Sequence variations from dbSNP and Humsavar for BOLA1 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs1044808 - 149,900,352(+) GCTGG(C/G)AGGTC reference, missense
rs11011 -- 149,900,607(-) GGAGA(G/T)TATGT utr-variant-3-prime
rs1548169 -- 149,900,664(-) TGAGT(A/G)ATTCT utr-variant-3-prime
rs1349532 -- 149,899,450(+) CATTG(C/T)TGGGT upstream-variant-2KB
rs1355237 -- 149,899,725(-) TTGTG(A/G)TTGGG intron-variant, utr-variant-5-prime

Structural Variations from Database of Genomic Variants (DGV) for BOLA1 Gene

Variant ID Type Subtype PubMed ID
dgv117e1 CNV Complex 17122850
nsv428235 CNV Gain 18775914
esv2750807 CNV Gain 17911159
dgv123e1 CNV Complex 17122850
dgv125e1 CNV Complex 17122850
nsv831525 CNV Gain 17160897
essv23032 CNV CNV 17122850
nsv831537 CNV Loss 17160897

Variation tolerance for BOLA1 Gene

Residual Variation Intolerance Score: 74.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.80; 47.48% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for BOLA1 Gene

Disorders for BOLA1 Gene

Relevant External Links for BOLA1

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator
Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for BOLA1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for BOLA1 Gene

Publications for BOLA1 Gene

  1. Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. (PMID: 20877624) Hendrickson S.L. … O'Brien S.J. (PLoS ONE 2010) 3 48 67
  2. Solution structure of a BolA-like protein from Mus musculus. (PMID: 14718656) Kasai T. … Yokoyama S. (Protein Sci. 2004) 2 3
  3. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3
  4. Panorama of ancient metazoan macromolecular complexes. (PMID: 26344197) Wan C. … Emili A. (Nature 2015) 3
  5. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3

Products for BOLA1 Gene

Sources for BOLA1 Gene