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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

BOK Gene

protein-coding GIFtS: 54
GCID: GC02P242517

BCL2-related ovarian killer

Explore 48 diseases affiliated with
BOK via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
BCL2-Related Ovarian Killer¹ ²		MGC4631¹
BCL2L9¹ ² ³		Bcl-2-Related Ovarian Killer Protein²
BOKL¹ ²		Bcl2-L-9³
Bcl-2-Like Protein 9² ³		Bcl2-L-9³
HBOK¹

External Ids:	HGNC: 1087¹	Entrez Gene: 666²	Ensembl: ENSG00000176720⁷	OMIM: 605404⁵	UniProtKB: Q9UMX3³

Export aliases for BOK gene to outside databases

Previous GC identifers: GC02U990010 GC02M239779 GC02P242818 GC02P242218 GC02P242146 GC02P234252

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for BOK:

The protein encoded by this gene belongs to the BCL2 family, members of which form homo- or heterodimers, and act as

anti- or proapoptotic regulators that are involved in a wide variety of cellular processes. Studies in rat show that

this protein has restricted expression in reproductive tissues, interacts strongly with some antiapoptotic BCL2

proteins, not at all with proapoptotic BCL2 proteins, and induces apoptosis in transfected cells. Thus, this protein

represents a proapoptotic member of the BCL2 family. (provided by RefSeq, Sep 2011)

UniProtKB/Swiss-Prot: BOK_HUMAN, Q9UMX3

Function: May play a role in apoptosis

Gene Wiki entry for BOK

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000002.11 NC_018913.1 NT_005416.13

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the BOK gene promoter:
AhR c-Fos AP-1 ATF-2 Arnt PPAR-alpha N-Myc c-Jun
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: BOK promoter sequence

Search SABiosciences Chromatin IP Primers for BOK

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat BOK

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2q37.3 Ensembl cytogenetic band: 2q37.3 HGNC cytogenetic band: 2q37.3

BOK Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
BOK gene location

GeneLoc information about chromosome 2 GeneLoc Exon Structure

GeneLoc location for GC02P242517: view genomic region (about GC identifiers)

Start:	242,498,136 bp from pter	End:	242,513,553 bp from pter
Size:	15,418 bases	Orientation:	plus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: BOK_HUMAN, Q9UMX3 (See protein sequence)

Recommended Name: Bcl-2-related ovarian killer protein

Size: 212 amino acids; 23280 Da

Explore the universe of human proteins at neXtProt for BOK: NX_Q9UMX3

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q9UMX3

BOK Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins: NP_115904.1

ENSEMBL proteins:

ENSP00000314132

Human Recombinant Protein Products:

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	Uscn Proteins for BOK

Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005634	nucleus	IDA	19095301
GO:0005737	cytoplasm	IDA	--
GO:0005739	mitochondrion	IDA	19095301
GO:0031966	mitochondrial membrane	IDA	15868100

BOK for ontologies About GeneDecksing

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	ThermoFisher Antibodies for BOK

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	Uscn ELISAs and CLIAs for BOK

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

BOK for domains About GeneDecksing

3 InterPro domains/families:

IPR002475 Bcl2-like

IPR026298 Blc2_fam

IPR026309 BOK

Graphical View of Domain Structure for InterPro Entry Q9UMX3

ProtoNet protein and cluster: Q9UMX3

2 Blocks protein families:

IPB000712 Apoptosis regulator Bcl-2 protein

IPB003093 Apoptosis regulator Bcl-2 protein

UniProtKB/Swiss-Prot: BOK_HUMAN, Q9UMX3

Similarity: Belongs to the Bcl-2 family

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Function Summary:

UniProtKB/Swiss-Prot: BOK_HUMAN, Q9UMX3

Function: May play a role in apoptosis

miRNA Products:		OriGene 3'-UTR Clone: BOK Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat BOK
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		hsa-miR-661 hsa-miR-4267
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Gene Editing
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Cell Line Products:		GenScript Custom overexpressing Cell Line Services for BOK
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In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for BOK

Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005515	protein binding	IPI	15868100
GO:0046982	protein heterodimerization activity	IEA	--
GO:0046983	protein dimerization activity	--	--
GO:0051400	BH domain binding	IEA	--

BOK for ontologies About GeneDecksing

1 GenomeRNAi human phenotype for BOK:

Increased G2M DNA content

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Unified GeneCards pathways About this table

See pathways by source

Super-pathway

contained gene-specific pathways

Apoptosis Modulation and Signaling

Apoptosis Modulation and Signaling

1.00

Apoptosis

0.38

TP53 network

TP53 network

1.00

3 BioSystems Pathways for BOK

	Apoptosis Modulation and Signaling
	Apoptosis
	TP53 network

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for BOK

STRING Interaction Network Preview (showing 5 interactants - click image to see 6)

5/6 Interacting proteins for BOK (Q9UMX3^{2, 3} ENSP00000314132⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 6)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
NOA1	Q8NC60²^,³, ENSP00000264230⁴	MINT-8249652 I2D: score=2 STRING: ENSP00000264230
MCL1	Q07820³, ENSP00000358022⁴	I2D: score=3 STRING: ENSP00000358022
BCL2A1	Q16548³, ENSP00000267953⁴	I2D: score=2 STRING: ENSP00000267953
BCL2L10	ENSP00000260442⁴	STRING: ENSP00000260442
MYC	ENSP00000367207⁴	STRING: ENSP00000367207

About this table

Gene Ontology (GO): 5/9 biological process terms (GO ID links to tree view) (see all 9): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006915	apoptotic process	IDA	15102863
GO:0006917	induction of apoptosis	IMP	--
GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process	IMP	--
GO:0007420	brain development	IEA	--
GO:0008283	cell proliferation	IEP	19095301

BOK for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

BOK for compounds About GeneDecksing

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for BOK
7 Novoseek chemical compound relationships for BOK gene About this table

Compound	-log (P-Val)	Hits	PubMed IDs for Articles with Shared Sentences (# sentences)
progesterone	11.4	2	12209691 (1), 10940486 (1)
estradiol	8.64	1	10940486 (1)
thymidine	8.53	1	18054556 (1)
oxygen	0	1	9274913 (1)
estrogen	0	1	12209691 (1)
retinoic acid	0	1	14592536 (1)
vegf	0	1	11329148 (1)

Search CenterWatch for drugs/clinical trials and news about BOK

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for BOK gene:

NM_032515.4

Unigene Cluster for BOK:

BCL2-related ovarian killer

Hs.293753 [show with all ESTs]

Unigene Representative Sequence: NM_032515

1 Ensembl transcript including schematic representation, and UCSC links where relevant:

ENST00000318407(uc002wbq.3)

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		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat BOK
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		hsa-miR-661 hsa-miR-4267
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Additional cDNA sequence:

AF174487.1 BT007272.1

6 DOTS entries:

DT.97843721 DT.445800 DT.75191678 DT.100728025 DT.100736833 DT.100718955

24/181 AceView cDNA sequences (see all 181):

BI820437 AW169875 BQ937494 BM991020 BQ225038 AI972382 AI754755 BM986756

AI929578 AI250619 W51860 BM761650 BI793225 CA312328 BU729827 BX460019

AA478794 BI792943 NM_032515 BQ648903 AI658760 AK125061 AI369428 BM762787

GeneLoc Exon Structure

5 Alternative Splicing Database (ASD) splice patterns (SP) for BOK About this scheme

ExUns:	1a	·	1b	·	1c	·	1d	·	1e	^	2	^	3	^	4	^	5	^	6a	·	6b	·	6c	·	6d	·	6e
SP1:									-				-
SP2:									-				-		-
SP3:
SP4:									-		-		-		-
SP5:											-		-		-

ECgene alternative splicing isoforms for BOK

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

BOK expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TGCCAGGACA

About this image

BOK expression in embryonic tissues and stem cells

Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

Stem Cell Differentiation: 1 LifeMap Cell

Name

Category

Definitive endoderm-like cells (A scalable, suspensi...)

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See BOK Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for BOK

SOURCE GeneReport for Unigene cluster: Hs.293753

UniProtKB/Swiss-Prot: BOK_HUMAN, Q9UMX3

Tissue specificity: Expressed in brain, liver, appendix and lymphoid tissues

SABiosciences Expression via Pathway-Focused PCR Arrays including BOK:

Apoptosis 384HT in human mouse rat

Apoptosis in human mouse rat

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In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for BOK

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of animals.

Orthologs for BOK gene from 6/17 species (see all 17) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
mouse (Mus musculus)	Mammalia	Bok^{1 , 5}	BCL2-related ovarian killer protein^{1, 5}	88.68(n)¹ 95.75(a)¹		1 (47.28 cM)⁵ 51800¹ NM_016778.2¹ NP_058058.1¹ 93685694⁵
chicken (Gallus gallus)	Aves	BOK¹	BCL2-related ovarian killer	78.62(n) 81.6(a)		395445 NM_204706.1 NP_990037.1
lizard (Anolis carolinensis)	Reptilia	BOK⁶	--	77(a)	1 ↔ 1	3(30476965-30501944)
African clawed frog (Xenopus laevis)	Amphibia	BJ069471.1²	--	71.27(n)		BJ069471.1
zebrafish (Danio rerio)	Actinopterygii	zgc64041²	similar to BCL2-related ovarian killer	75.55(n)		394160 BC053218.1
fruit fly (Drosophila melanogaster)	Insecta	debcl¹	death executioner Bcl-2 homologue	54.79(n) 39.04(a)		53585 NM_176098.2 NP_788278.1

ENSEMBL Gene Tree for BOK (if available)
TreeFam Gene Tree for BOK (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 2 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs145163905^1,2		--	242496194(+)	`CTCCCG/TCATTT`	2	--	us2k¹ int¹		0	--	--	--	--
rs148343525^1,2		--	242496242(+)	`TTTTTA/TAACTG`	2	--	us2k¹ int¹		0	--	--	--	--
rs181417647^1,2		--	242496266(+)	`CTCAAC/TGAAAC`	2	--	us2k¹ int¹		0	--	--	--	--
rs184867852^1,2		--	242496267(+)	`TCAATG/TAAACC`	2	--	us2k¹ int¹		0	--	--	--	--
rs7572476^1,2	C,F,A,H,	--	242496325(+)	`CAATGT/CATTTA`	2	--	us2k¹ int¹		22		NS EA NA WA CSA	2576
rs188436893^1,2		--	242496332(+)	`TTTAAG/TTGGTG`	2	--	us2k¹ int¹		0	--	--	--	--
rs73123521^1,2	C,	--	242496387(+)	`AAGTTG/ATGTAT`	2	--	int¹ us2k¹		2		WA	120
rs180910291^1,2		--	242496464(+)	`TAGTAG/TCTACA`	2	--	int¹ us2k¹		0	--	--	--	--
rs141528340^1,2		--	242496859(+)	`AGCTGA/GGATTA`	2	--	us2k¹ int¹		0	--	--	--	--
rs185124605^1,2		--	242496869(+)	`ACAGAC/GACCTG`	2	--	int¹ us2k¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for BOK (242498136 - 242513553 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 9 variations for BOK
8 CNVs: 4331 61901 68298 63354 44021 3410 39283 98193
1 Indel: 68299

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing BOK

DNA2.0 Custom Variant and Variant Library Synthesis for BOK

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

BOK for disorders           About GeneDecksing

OMIM gene information: 605404    OMIM disorders: --

20/48 diseases for BOK (see all 48):    About MalaCards

werdnig-hoffmann disease pre-eclampsia polycythemia vera myasthenia gravis

granular cell tumor parathyroid adenoma systemic lupus erythematosus lupus erythematosus

myelodysplastic syndrome polycythemia acute myeloid leukemia myasthenia

leukemia/lymphoma myeloid leukemia eclampsia gallbladder carcinoma

endometrial adenocarcinoma rheumatoid arthritis ovarian cancer lymphocytic leukemia

10/11 Novoseek disease relationships for BOK gene (see all 11) About this table

Disease	-log (P-Val)	Hits	PubMed IDs for Articles with Shared Sentences (# sentences)
tumors	24.6	8	15905199 (1), 16528364 (1), 12197230 (1), 16615003 (1) (see all 7)
aggressiveness	17.9	1	12680148 (1)
myelodysplastic syndromes	14.1	1	9886323 (1)
glioma	12.5	1	10873619 (1)
ovarian cancer	10.9	1	9615792 (1)
colorectal cancer	10.5	1	19453036 (1)
carcinoma	8.39	1	12680148 (1)
adenocarcinoma	6.21	1	9180925 (1)
necrosis	0	2	16528364 (1), 10385052 (1)
breast cancer	0	2	14592536 (1), 9252670 (1)

Export disorders for BOK gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for BOK gene, integrated from 9 sources (see all 103):
(articles sorted by number of sources associating them with BOK)

Utopia: connect your pdf to the dynamic
world of online information

Evolutionarily conserved Bok proteins in the Bcl-2 family. (PubMed id 11034351)^{1, 2, 3} Zhang H.... De Geyter C. (2000)
BOK and NOXA are essential mediators of p53-dependent apoptosis. (PubMed id 15102863)^{1, 3} Yakovlev A.G....Faden A.I. (2004)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
Mtd, a novel Bcl-2 family member activates apoptosis in the absence of heterodimerization with Bcl-2 and Bcl-XL. (PubMed id 9535847)^{1, 2} Inohara N.... Nunez G. (1998)
Bok is a pro-apoptotic Bcl-2 protein with restricted expression in reproductive tissues and heterodimerizes with selective anti-apoptotic Bcl-2 family members. (PubMed id 9356461)^{1, 3} Hsu S.Y....Hsueh A.J. (1997)
A natural antisense transcript, BOKAS, regulates the pro-apoptotic activity of human Bok. (PubMed id 19287972)^{1, 9} Zhang H....De Geyter C. (2009)
Functional genomics identifies therapeutic targets for MYC-driven cancer. (PubMed id 22623531)¹ Toyoshima M....Grandori C. (2012)
A directed protein interaction network for investigat ing intracellular signal transduction. (PubMed id 21900206)¹ Vinayagam A....Wanker E.E. (2011)
Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)¹ Kim W....Gygi S.P. (2011)
Mtd/Bok takes a swing: proapoptotic Mtd/Bok regulates trophoblast cell proliferation during human placental development and in preec lampsia. (PubMed id 19942931)¹ Ray J.E....Caniggia I. (2010)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Disorders
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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 666	HGNC: 1087	AceView: BOK	Ensembl:ENSG00000176720	euGenes: HUgn666
ECgene: BOK	H-InvDB: BOK

(According to HUGE)
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(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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Name	Description
PharmGKB entry for BOK	Pharmacogenomics, SNPs, Pathways
ATLAS Chromosomes in Cancer entry for BOK	Genetics and Cytogenetics in Oncology and Haematology

Intellectual Property for BOK gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

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Patent Information for BOK gene:
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GeneCards and IP:
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