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Aliases for BOD1L2 Gene

Aliases for BOD1L2 Gene

  • Biorientation Of Chromosomes In Cell Division 1-Like 2 2 3
  • Biorientation Of Chromosomes In Cell Division Protein 1 Pseudogene 3 4
  • Biorientation Of Chromosomes In Cell Division 1 Pseudogene 2 3
  • Family With Sequence Similarity 44, Member C 2 3
  • FAM44C 3 4
  • BOD1P 3 4
  • Putative Biorientation Of Chromosomes In Cell Division Protein 1 Pseudogene 3
  • Putative Biorientation Of Chromosomes In Cell Division Protein 1-Like 2 3
  • Biorientation Of Chromosomes In Cell Division Protein 1-Like 2 3
  • Putative Protein FAM44C 3
  • Protein FAM44C 4

External Ids for BOD1L2 Gene

Previous HGNC Symbols for BOD1L2 Gene

  • FAM44C
  • BOD1P

Previous GeneCards Identifiers for BOD1L2 Gene

  • GC18P054826
  • GC18P054831
  • GC18P054835
  • GC18P054840

Summaries for BOD1L2 Gene

GeneCards Summary for BOD1L2 Gene

BOD1L2 (Biorientation Of Chromosomes In Cell Division 1-Like 2) is a Protein Coding gene. An important paralog of this gene is BOD1L1.

UniProtKB/Swiss-Prot for BOD1L2 Gene

  • May play a role in proper chromosome biorientation through the detection or correction of syntelic attachments in mitotic spindles.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for BOD1L2 Gene

Genomics for BOD1L2 Gene

Genomic Location for BOD1L2 Gene

Start:
57,147,062 bp from pter
End:
57,150,408 bp from pter
Size:
3,347 bases
Orientation:
Plus strand

Genomic View for BOD1L2 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for BOD1L2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for BOD1L2 Gene

No data available for Regulatory Elements for BOD1L2 Gene

Proteins for BOD1L2 Gene

  • Protein details for BOD1L2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8IYS8-BD1L2_HUMAN
    Recommended name:
    Biorientation of chromosomes in cell division protein 1-like 2
    Protein Accession:
    Q8IYS8
    Secondary Accessions:
    • B3KXU4
    • Q8WW13

    Protein attributes for BOD1L2 Gene

    Size:
    172 amino acids
    Molecular mass:
    18075 Da
    Quaternary structure:
    No Data Available

neXtProt entry for BOD1L2 Gene

Proteomics data for BOD1L2 Gene at MOPED

Post-translational modifications for BOD1L2 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for BOD1L2 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for BOD1L2 Gene

Domains for BOD1L2 Gene

Protein Domains for BOD1L2 Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

Q8IYS8

UniProtKB/Swiss-Prot:

BD1L2_HUMAN :
  • Q8IYS8
Family:
  • Belongs to the BOD1 family.
genes like me logo Genes that share domains with BOD1L2: view

No data available for Gene Families and Suggested Antigen Peptide Sequences for BOD1L2 Gene

Function for BOD1L2 Gene

Molecular function for BOD1L2 Gene

UniProtKB/Swiss-Prot Function: May play a role in proper chromosome biorientation through the detection or correction of syntelic attachments in mitotic spindles.

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for BOD1L2 Gene

Localization for BOD1L2 Gene

Subcellular locations from UniProtKB/Swiss-Prot for BOD1L2 Gene

Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Chromosome, centromere, kinetochore.

Gene Ontology (GO) - Cellular Components for BOD1L2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000777 condensed chromosome kinetochore IEA --
GO:0005737 cytoplasm IEA --
GO:0005815 microtubule organizing center IEA --
genes like me logo Genes that share ontologies with BOD1L2: view

No data available for Subcellular locations from COMPARTMENTS for BOD1L2 Gene

Pathways for BOD1L2 Gene

SuperPathways for BOD1L2 Gene

No Data Available

Interacting Proteins for BOD1L2 Gene

Gene Ontology (GO) - Biological Process for BOD1L2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007067 mitotic nuclear division IEA --
GO:0051301 cell division IEA --
genes like me logo Genes that share ontologies with BOD1L2: view

No data available for Pathways by source for BOD1L2 Gene

Transcripts for BOD1L2 Gene

mRNA/cDNA for BOD1L2 Gene

(76) Selected AceView cDNA sequences:
(3) Additional mRNA sequences :
(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for BOD1L2 Gene

Biorientation of chromosomes in cell division 1-like 2:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for BOD1L2

Primer Products

  • OriGene qSTAR qPCR primer pairs in human,mouse,rat for BOD1L2
  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for BOD1L2 Gene

No ASD Table

Relevant External Links for BOD1L2 Gene

GeneLoc Exon Structure for
BOD1L2
ECgene alternative splicing isoforms for
BOD1L2

Expression for BOD1L2 Gene

mRNA expression in normal human tissues for BOD1L2 Gene

mRNA differential expression in normal tissues according to GTEx for BOD1L2 Gene

This gene is overexpressed in Testis (52.7).

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for BOD1L2 Gene

SOURCE GeneReport for Unigene cluster for BOD1L2 Gene Hs.127882

genes like me logo Genes that share expressions with BOD1L2: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for BOD1L2 Gene

Orthologs for BOD1L2 Gene

This gene was present in the common ancestor of animals.

Orthologs for BOD1L2 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia BOD1L2 35
  • 99.79 (n)
  • 100 (a)
BOD1L2 36
  • 91 (a)
OneToOne
cow
(Bos Taurus)
Mammalia BOD1 36
  • 71 (a)
OneToMany
dog
(Canis familiaris)
Mammalia BOD1 36
  • 71 (a)
OneToMany
mouse
(Mus musculus)
Mammalia Bod1 36
  • 77 (a)
OneToMany
Bod1-ps 16
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 50 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 52 (a)
OneToMany
chicken
(Gallus gallus)
Aves -- 36
  • 67 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia -- 36
  • 61 (a)
OneToMany
zebrafish
(Danio rerio)
Actinopterygii bod1 36
  • 42 (a)
OneToMany
fruit fly
(Drosophila melanogaster)
Insecta CG5514 36
  • 5 (a)
OneToMany
Species with no ortholog for BOD1L2:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for BOD1L2 Gene

ENSEMBL:
Gene Tree for BOD1L2 (if available)
TreeFam:
Gene Tree for BOD1L2 (if available)

Paralogs for BOD1L2 Gene

Paralogs for BOD1L2 Gene

Selected SIMAP similar genes for BOD1L2 Gene using alignment to 1 proteins:

Pseudogenes.org Pseudogenes for BOD1L2 Gene

genes like me logo Genes that share paralogs with BOD1L2: view

Variants for BOD1L2 Gene

Sequence variations from dbSNP and Humsavar for BOD1L2 Gene

SNP ID Clin Chr 18 pos Sequence Context AA Info Type MAF
rs7234572 -- 57,150,335(+) CATGC(A/C)TGCCC utr-variant-3-prime
rs8085797 -- 57,149,352(+) AAAGA(A/G)ACCAG utr-variant-3-prime
rs8086063 -- 57,149,529(+) AAATG(A/G)TTCTT utr-variant-3-prime
rs9956688 -- 57,148,963(+) GGTCT(A/G)ACGAA utr-variant-3-prime
rs12605647 -- 57,150,847(+) CAGGG(C/T)GACTC downstream-variant-500B

Relevant External Links for BOD1L2 Gene

HapMap Linkage Disequilibrium report
BOD1L2

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for BOD1L2 Gene

Disorders for BOD1L2 Gene

No disorders were found for BOD1L2 Gene.

No data available for UniProtKB/Swiss-Prot for BOD1L2 Gene

Publications for BOD1L2 Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  2. Bod1, a novel kinetochore protein required for chromosome biorientation. (PMID: 17938248) Porter I.M. … Swedlow J.R. (J. Cell Biol. 2007) 2 3
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 4
  4. DNA sequence and analysis of human chromosome 18. (PMID: 16177791) Nusbaum C. … Lander E.S. (Nature 2005) 4
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for BOD1L2 Gene

Sources for BOD1L2 Gene

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