BOD1L2 Gene
protein-coding GIFtS: 29
GCID: GC18P054831
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biorientation of chromosomes in cell division 1-like 2(Previous names: family with sequence similarity 44, member C, biorientation...)
(Previous symbols: FAM44C, BOD1P)
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Aliases
for BOD1L2 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA
Quality score for the ORGUL clustered with this gene is 3
| Aliases |
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| Biorientation Of Chromosomes In Cell Division 1-Like 21 2 | | Putative Biorientation Of Chromosomes In Cell Division Protein 1 Pseudogene2 3 | | BOD1P1 2 3 | | Putative Protein FAM44C2 3 | | FAM44C1 2 3 | | MGC336081 | | Biorientation Of Chromosomes In Cell Division 1 Pseudogene1 2 | | Biorientation Of Chromosomes In Cell Division Protein 1-Like 22 | | Family With Sequence Similarity 44, Member C1 2 | | Putative Biorientation Of Chromosomes In Cell Division Protein 1-Like 22 |
| External Ids: | HGNC: 285051 | Entrez Gene: 2842572 | Ensembl: ENSG000002280757 | UniProtKB: Q8IYS83 | | ORGUL members: | |
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| NONCODE:n409206 | |
Export aliases for BOD1L2 gene to outside databasesPrevious GC identifer: GC18P054826
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Summaries
for BOD1L2 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for BOD1L2 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000018.9 NC_018929.1 NT_025028.14
Regulatory elements:
 Search SABiosciences Regulatory transcription factor binding sites for BOD1L2
Other transcription factors
Search SABiosciences Chromatin IP Primers for BOD1L2
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat BOD1L2 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 18q21.31 Ensembl cytogenetic band: 18q21.31 HGNC cytogenetic band: 18q21.31BOD1L2 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 18 GeneLoc Exon Structure GeneLoc location for GC18P054831: view genomic region
(about GC identifiers)
Start:
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54,814,293 bp from pter |
End:
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54,817,639 bp from pter |
Size:
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3,347 bases |
Orientation:
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plus strand |
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Proteins
for BOD1L2 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: BD1L2_HUMAN, Q8IYS8 (See
protein sequence)Recommended Name: Putative biorientation of chromosomes in cell division protein 1-like 2 Size: 172 amino acids; 18075 Da
Caution: Could be the product of a pseudogene
Secondary accessions: B3KXU4 Q8WW13Explore the universe of human proteins at neXtProt for BOD1L2: NX_Q8IYS8
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q8IYS8
BOD1L2 Protein expression data from MOPED and PaxDb: --
REFSEQ proteins: NP_001244893.1
ENSEMBL proteins: ENSP00000467843 ENSP00000442342
Human Recombinant Protein Products for BOD1L2:
BOD1L2 Antibody Products:
Assay Products for BOD1L2: |
Protein
Domains /
Families
for BOD1L2 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
BOD1L2 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q8IYS8ProtoNet protein and cluster: Q8IYS8 UniProtKB/Swiss-Prot: BD1L2_HUMAN, Q8IYS8Similarity: Belongs to the BOD1 family |
Function
for BOD1L2 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
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Animal Models:
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for BOD1L2 |
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Pathways & Interactions
for BOD1L2 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for BOD1L2
|
Drugs & Compounds
for BOD1L2 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for BOD1L2
Search CenterWatch for drugs/clinical trials and news about BOD1L2 / BD1L2 
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Transcripts
for BOD1L2 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
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REFSEQ mRNAs for BOD1L2 gene: NM_001257964.1 Unigene Cluster for BOD1L2: Biorientation of chromosomes in cell division 1-like 2 Hs.127882 [show with all ESTs]Unigene Representative Sequence: NM_0012579642 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000585477 ENST00000420277
Additional cDNA sequence: AK127964.1 BC021740.1 BC035018.1 1 DOTS entry: DT.411211 24/76 AceView cDNA sequences (see all 76): AA992718 BC035018 AL042836 AA403023 AA725583 AA398422 AA993365 AI198878 AI221130 BC021740 BM564054 BI830357 AK127964 AI183840 AI184568 BI830029 BI826208 BU567719 BM553953 AI018804 BG773463 BI830866 BM553229 BG717138
GeneLoc Exon Structure
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Expression
for BOD1L2 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| See probesets specificity/sensitivity at GeneAnnot
CGAP TAG: --
Genevestigator expression for BOD1L2
SOURCE GeneReport for Unigene cluster: Hs.127882
SABiosciences Custom PCR Arrays for BOD1L2
Primer
Products: |  | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for BOD1L2
Browse OriGene validated miRNA SYBR primer pairs
| | | Search SABiosciences RT2 qPCR
Primer Assays in human, mouse, rat BOD1L2 | | | Search QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat BOD1L2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat BOD1L2 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for BOD1L2 |
Orthologs
for BOD1L2 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
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This gene was present in the common ancestor of animals.
Orthologs for BOD1L2 gene from 4/13 species (see all 13) About this table
ENSEMBL Gene Tree for BOD1L2 (if available)
TreeFam Gene Tree for BOD1L2 (if available) |
Paralogs
for BOD1L2 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for BOD1L2 gene
- BOD1L12 BOD12
2 SIMAP similar genes for BOD1L2 using alignment to 2 protein entries: BD1L2_HUMAN (see all proteins):BOD1 BOD1L1
BOD1L2 for paralogs About GeneDecksing
1 Pseudogenes.org Pseudogene for BOD1L2
PGOHUM00000258676
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Genomic Variants
for BOD1L2 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
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| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 18 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
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HapMap Linkage Disequilibrium report for BOD1L2 (54814293 - 54817639 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for BOD1L2: -- | SABiosciences Cancer Mutation PCR Assays |
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Disorders
/ Diseases
for BOD1L2 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for BOD1L2 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for BOD1L2 gene integrated from 9 sources:
(articles sorted by number of sources associating them with BOD1L2) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Bod1, a novel kinetochore protein required for chromosome biorientation. (PubMed id 17938248)1, 3 Porter I.M.... Swedlow J.R. (2007)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (2002)
- DNA sequence and analysis of human chromosome 18. (PubMed id 16177791)2 Nusbaum C.... Lander E.S. (2005)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)2 Ota T.... Sugano S. (2004)
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External Searches for BOD1L2 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
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Genome Databases showing BOD1L2 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
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Other Databases showing BOD1L2 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing BOD1L2 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for BOD1L2 | Pharmacogenomics, SNPs, Pathways |
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About This Section
| Patent Information for BOD1L2 gene:
Search GeneIP for patents involving BOD1L2
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for BOD1L2 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
|
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|  | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat BOD1L2 | | | Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing BOD1L2 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat BOD1L2 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat BOD1L2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat BOD1L2 | | | Search QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat BOD1L2 |
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| | | | Search Tocris compounds for BOD1L2 |
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 | | | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for BOD1L2 |
|  |  |  |  | | | | Search ThermoFisher Antibodies for BOD1L2 |
| | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat BOD1L2 |
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