BOD1L1 Gene
protein-coding GIFtS: 40
GCID: GC04M013571
|
|
biorientation of chromosomes in cell division 1-like 1(Previous names: family with sequence similarity 44, member A, biorientation...)
(Previous symbols: FAM44A, BOD1L)
| |
Aliases
for BOD1L1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Biorientation Of Chromosomes In Cell Division 1-Like 11 2 | | FLJ332151 | | BOD1L1 2 3 | | Biorientation Of Chromosomes In Cell Division 1-Like1 | | FAM44A1 2 3 | | Biorientation Of Chromosomes In Cell Division Protein 1-Like 12 | | Family With Sequence Similarity 44, Member A1 2 | | Protein FAM44A3 | | KIAA13271 3 | | |
Export aliases for BOD1L1 gene to outside databases |
Summaries
for BOD1L1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for BOD1L1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000004.11 NC_018915.1 NT_006316.16
Regulatory elements:
 Search SABiosciences Regulatory transcription factor binding sites for BOD1L1
Other transcription factors
Search SABiosciences Chromatin IP Primers for BOD1L1
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat BOD1L1 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 4p16.1 Ensembl cytogenetic band: 4p15.33 HGNC cytogenetic band: 4p16.1BOD1L1 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 4 GeneLoc Exon Structure GeneLoc location for GC04M013571: view genomic region
(about GC identifiers)
Start:
|
13,570,362 bp from pter |
End:
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13,629,347 bp from pter |
Size:
|
58,986 bases |
Orientation:
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minus strand |
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Proteins
for BOD1L1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: BD1L1_HUMAN, Q8NFC6 (See
protein sequence)Recommended Name: Biorientation of chromosomes in cell division protein 1-like 1 Size: 3051 amino acids; 330466 Da
Sequence caution: Sequence=AAH16987.1; Type=Erroneous initiation; Note=Translation N-terminally extended;Sequence=BAB15299.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Potential poly-A sequence;Sequence=CAB70705.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Potential poly-A sequence;
Secondary accessions: Q6P0M8 Q96AL1 Q9H6G0 Q9NTD6 Q9P2L9Explore the universe of human proteins at neXtProt for BOD1L1: NX_Q8NFC6
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q8NFC6
BOD1L1 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_683692.2
ENSEMBL proteins: ENSP00000040738 ENSP00000425492 ENSP00000420541
Human Recombinant Protein Products:
BOD1L1 Antibody Products:
Assay Products for BOD1L1: |
Protein
Domains /
Families
for BOD1L1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
BOD1L1 for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q8NFC6ProtoNet protein and cluster: Q8NFC6 UniProtKB/Swiss-Prot: BD1L1_HUMAN, Q8NFC6Similarity: Belongs to the BOD1 familySimilarity: Contains 1 A.T hook DNA-binding domain |
Function
for BOD1L1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for BOD1L1 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for BOD1L1
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript Custom all cDNA clones Services for BOD1L1 | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for BOD1L1 | |  | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat BOD1L1 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for BOD1L1 |
Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0003677 | DNA binding |
IEA | -- |
BOD1L1 for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for BOD1L1:
|
Pathways & Interactions
for BOD1L1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for BOD1L1
STRING Interaction
Network Preview (showing 3 interactants - click image to see more details)
3 Interacting proteins for BOD1L1 (Q8NFC63 ENSP000000407384) via UniProtKB, MINT, STRING, and/or I2DAbout this table
|
Drugs & Compounds
for BOD1L1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for BOD1L1
Search CenterWatch for drugs/clinical trials and news about BOD1L1 / BD1L1
|
Transcripts
for BOD1L1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for BOD1L1 gene: NM_148894.2 Unigene Cluster for BOD1L1: Biorientation of chromosomes in cell division 1-like 1 Hs.444517 [show with all ESTs]Unigene Representative Sequence: NM_1488946 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000040738(uc003gmz.1 uc010idr.1) ENST00000507943 ENST00000505343
ENST00000509897 ENST00000511119 ENST00000482713(uc010ids.1)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for BOD1L1 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for BOD1L1
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript Custom all cDNA clones Services for BOD1L1 | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for BOD1L1 | | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat BOD1L1 |
Additional cDNA sequence: AB037748.2 AF528529.1 AK025361.1 AK025965.1 AK090534.1 AK122806.1 AK298130.1 AL137350.1 AL137652.1 BC016987.1 BC043603.1 BC065546.1 BC087835.1 BX648206.1 11 DOTS entries: DT.95378777 DT.97794305 DT.40250416 DT.212643 DT.100740994 DT.100740779 DT.40308756 DT.100648557 DT.431581 DT.75165416 DT.426944 24/175 AceView cDNA sequences (see all 175): AL137652 NM_148894 CB243155 CA428205 AW075895 AL137350 AL044271 BU735907 BU620995 AI221325 AA974778 CR614809 BM554814 AI784290 AI784648 AI522218 AI889584 AW291533 BM697225 BG058609 AA459784 AW573547 AI587243 AA748754
GeneLoc Exon Structure
5 Alternative Splicing Database (ASD) splice patterns (SP) for BOD1L1 About this scheme
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4a | · | 4b | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11a | · | 11b | ^ | 12 | ^ | 13 | ^ | 14a | · | 14b | ^ | 15 | ^ | 16 | ^ | 17 | ^ | 18a | · | 18b | · | 18c | · | 18d |
|---|
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| SP1: | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | - | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | - | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | | |
ECgene alternative splicing isoforms for BOD1L1
|
Expression
for BOD1L1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| See probesets specificity/sensitivity at GeneAnnot
CGAP TAG: --
See BOD1L1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for BOD1L1
SOURCE GeneReport for Unigene cluster: Hs.444517
SABiosciences Custom PCR Arrays for BOD1L1
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for BOD1L1
Browse OriGene validated miRNA SYBR primer pairs
| | | Search SABiosciences RT2 qPCR
Primer Assays in human, mouse, rat BOD1L1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat BOD1L1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat BOD1L1 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for BOD1L1 |
Orthologs
for BOD1L1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for BOD1L1 gene from 5/16 species (see all 16) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
BOD1L1 |
biorientation of chromosomes in cell division 1-like |
59.83(n)
47.38(a) |
|
422838 XM_420784.3 XP_420784.3 |
lizard
(Anolis carolinensis) |
Reptilia |
BOD1L6 |
-- |
42(a) |
1 ↔ 1 |
GL343366.1(235458-265366) |
African clawed frog
(Xenopus laevis) |
Amphibia |
Xl.212962 |
Xenopus laevis transcribed sequence with weak similarity more |
78.03(n) |
|
BU911331.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
CABZ01073253.16 |
-- |
29(a) |
1 ↔ 1 |
14(9802-19183) |
honey bee
(Apis mellifera) |
Insecta |
-- |
-- |
16(a) |
possible ortholog |
GroupUn.79(50548-55103) |
ENSEMBL Gene Tree for BOD1L1 (if available)
TreeFam Gene Tree for BOD1L1 (if available) |
Paralogs
for BOD1L1 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for BOD1L1 gene
- BOD12 BOD1L22
2 SIMAP similar genes for BOD1L1 using alignment to 3 protein entries: BD1L1_HUMAN (see all proteins):BOD1 BOD1L2
BOD1L1 for paralogs About GeneDecksing
|
Genomic Variants
for BOD1L1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
| | SABiosciences Cancer Mutation PCR Assays |
|
Disorders
/ Diseases
for BOD1L1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
BOD1L1 for disorders About GeneDecksing
3  diseases for BOD1L1: About MalaCardspancreatic cancer myeloma pancreatitis
Export disorders for BOD1L1 gene to outside databases
|
Publications
for BOD1L1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for BOD1L1 gene, integrated from 9 sources (see all 24):
(articles sorted by number of sources associating them with BOD1L1) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Tryptic digestion of ubiquitin standards reveals an improved strategy for identifying ubiquitinated proteins by mass spectrometry. (PubMed id 17370265)1, 2 Denis N.J.... Figeys D. (2007)
- Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (2006)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10718198)1, 2 Nagase T.... Ohara O. (2000)
- Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
- Identification of ubiquitinated proteins from human m ultiple myeloma U266 cells by proteomics. (PubMed id 22108332)1 Jia H....He Q. (2011)
- A data set of human endogenous protein ubiquitination sites. (PubMed id 20972266)1 Shi Y....Qin J. (2011)
- Proliferating cell nuclear antigen (PCNA)-associated KIAA0101/PAF15 protein is a cell cycle-regulated anaphase-promoting complex/cyc losome substrate. (PubMed id 21628590)1 Emanuele M.J....Elledge S.J. (2011)
- System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PubMed id 21406692)2 Rigbolt K.T....Blagoev B. (2011)
|
External Searches for BOD1L1 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing BOD1L1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing BOD1L1 gene
(According to HUGE)
About This Section
| |
Specialized Databases showing BOD1L1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for BOD1L1 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for BOD1L1 gene:
Search GeneIP for patents involving BOD1L1
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for BOD1L1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for BOD1L1 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for BOD1L1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for BOD1L1 | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | Browse OriGene siRNAs | | OriGene 3'-UTR Clone for BOD1L1 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for BOD1L1 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for BOD1L1 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat BOD1L1 | | | Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing BOD1L1 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat BOD1L1 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat BOD1L1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat BOD1L1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat BOD1L1 |
| |
 |  |  |  | |
| | | | Search Tocris compounds for BOD1L1 |
| |  |  |  |  | | | | |
 |
 |
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 | | | BOD1L1 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for BOD1L1 |
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| | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat BOD1L1 |
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