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Aliases for BOD1 Gene

Aliases for BOD1 Gene

  • Biorientation Of Chromosomes In Cell Division 1 2 3
  • Family With Sequence Similarity 44, Member B 2 3
  • Biorientation Defective 1 2 3
  • FAM44B 3 4
  • Biorientation Of Chromosomes In Cell Division Protein 1 3
  • Biorientation Defective Protein 1 4
  • Protein FAM44B 4

External Ids for BOD1 Gene

Previous HGNC Symbols for BOD1 Gene

  • FAM44B

Previous GeneCards Identifiers for BOD1 Gene

  • GC05M172968
  • GC05M168131

Summaries for BOD1 Gene

GeneCards Summary for BOD1 Gene

BOD1 (Biorientation Of Chromosomes In Cell Division 1) is a Protein Coding gene. An important paralog of this gene is BOD1L1.

UniProtKB/Swiss-Prot for BOD1 Gene

  • Required for proper chromosome biorientation through the detection or correction of syntelic attachments in mitotic spindles.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for BOD1 Gene

Genomics for BOD1 Gene

Regulatory Elements for BOD1 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for BOD1 Gene

173,607,145 bp from pter
173,616,703 bp from pter
9,559 bases
Minus strand

Genomic View for BOD1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for BOD1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for BOD1 Gene

Proteins for BOD1 Gene

  • Protein details for BOD1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Biorientation of chromosomes in cell division protein 1
    Protein Accession:
    Secondary Accessions:
    • B4DXH8
    • Q9BTW1

    Protein attributes for BOD1 Gene

    185 amino acids
    Molecular mass:
    19196 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for BOD1 Gene


neXtProt entry for BOD1 Gene

Proteomics data for BOD1 Gene at MOPED

Post-translational modifications for BOD1 Gene

  • Ubiquitination at Lys79 and Lys140
  • Modification sites at PhosphoSitePlus

Other Protein References for BOD1 Gene

No data available for DME Specific Peptides for BOD1 Gene

Domains for BOD1 Gene

Protein Domains for BOD1 Gene


Suggested Antigen Peptide Sequences for BOD1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the BOD1 family.
  • Belongs to the BOD1 family.
genes like me logo Genes that share domains with BOD1: view

No data available for Gene Families for BOD1 Gene

Function for BOD1 Gene

Molecular function for BOD1 Gene

UniProtKB/Swiss-Prot Function:
Required for proper chromosome biorientation through the detection or correction of syntelic attachments in mitotic spindles.

Animal Model Products

miRNA for BOD1 Gene

miRTarBase miRNAs that target BOD1

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , Transcription Factor Targets and HOMER Transcription for BOD1 Gene

Localization for BOD1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for BOD1 Gene

Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Chromosome, centromere, kinetochore. Note=Localizes at the centrosomes throughout the cell cycle, only dissociating during cytokinesis. Localizes at the kinetochore from prometaphase until anaphase.

Subcellular locations from

Jensen Localization Image for BOD1 Gene COMPARTMENTS Subcellular localization image for BOD1 gene
Compartment Confidence
cytoskeleton 5
cytosol 2
extracellular 1
nucleus 1

Gene Ontology (GO) - Cellular Components for BOD1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000776 kinetochore --
GO:0000777 condensed chromosome kinetochore IEA --
GO:0005737 cytoplasm IEA --
GO:0005815 microtubule organizing center IEA --
GO:0005856 cytoskeleton --
genes like me logo Genes that share ontologies with BOD1: view

Pathways for BOD1 Gene

SuperPathways for BOD1 Gene

No Data Available

Interacting Proteins for BOD1 Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
Selected Interacting proteins: ENSP00000309644 for BOD1 Gene via STRING

Symbol External ID(s) Details

Gene Ontology (GO) - Biological Process for BOD1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007067 mitotic nuclear division IEA --
GO:0051301 cell division IEA --
genes like me logo Genes that share ontologies with BOD1: view

No data available for Pathways by source for BOD1 Gene

Transcripts for BOD1 Gene

Unigene Clusters for BOD1 Gene

Biorientation of chromosomes in cell division 1:
Representative Sequences:

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for BOD1

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for BOD1 Gene

ExUns: 1a · 1b ^ 2a · 2b · 2c ^ 3a · 3b ^ 4 ^ 5a · 5b · 5c · 5d · 5e · 5f
SP1: - - -
SP2: - - - -
SP3: - -
SP4: - - - - -
SP5: - - -
SP6: - - - - - -

Relevant External Links for BOD1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for BOD1 Gene

mRNA expression in normal human tissues for BOD1 Gene

Protein differential expression in normal tissues for BOD1 Gene

This gene is overexpressed in Plasma (36.1), Fetal Brain (15.7), and Fetal ovary (10.2).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for BOD1 Gene

SOURCE GeneReport for Unigene cluster for BOD1 Gene Hs.425091

genes like me logo Genes that share expressions with BOD1: view

Expression partners for BOD1 Gene

* - Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for BOD1 Gene

Orthologs for BOD1 Gene

This gene was present in the common ancestor of animals.

Orthologs for BOD1 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia BOD1 35
  • 93.92 (n)
  • 96.62 (a)
BOD1 36
  • 93 (a)
(Canis familiaris)
Mammalia BOD1 35
  • 94.37 (n)
  • 96.62 (a)
BOD1 36
  • 92 (a)
(Mus musculus)
Mammalia Bod1 35
  • 89.19 (n)
  • 96.62 (a)
Bod1 16
Bod1 36
  • 88 (a)
(Pan troglodytes)
Mammalia BOD1 35
  • 99.82 (n)
  • 100 (a)
BOD1 36
  • 90 (a)
(Rattus norvegicus)
Mammalia Bod1 35
  • 89.57 (n)
  • 97.28 (a)
(Monodelphis domestica)
Mammalia -- 36
  • 61 (a)
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 63 (a)
(Gallus gallus)
Aves BOD1 35
  • 84.25 (n)
  • 92.47 (a)
-- 36
  • 79 (a)
(Anolis carolinensis)
Reptilia -- 36
  • 73 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia bod1 35
  • 72.83 (n)
  • 83.56 (a)
Str.4589 35
African clawed frog
(Xenopus laevis)
Amphibia Xl.3658 35
(Danio rerio)
Actinopterygii bod1 35
  • 72.63 (n)
  • 78.05 (a)
wufb24f11 35
bod1 36
  • 48 (a)
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.8879 35
fruit fly
(Drosophila melanogaster)
Insecta CG5514 36
  • 5 (a)
Species with no ortholog for BOD1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for BOD1 Gene

Gene Tree for BOD1 (if available)
Gene Tree for BOD1 (if available)

Paralogs for BOD1 Gene

Paralogs for BOD1 Gene

(2) SIMAP similar genes for BOD1 Gene using alignment to 4 proteins: Pseudogenes for BOD1 Gene

genes like me logo Genes that share paralogs with BOD1: view

Variants for BOD1 Gene

Sequence variations from dbSNP and Humsavar for BOD1 Gene

SNP ID Clin Chr 05 pos Sequence Context AA Info Type MAF
rs540844362 -- 173,609,003(+) AATGA(A/G)GCATC intron-variant
rs541011030 -- 173,610,015(+) AATAG(-/ACAA)ACAAA intron-variant
rs541632197 -- 173,615,507(+) TGAAA(A/G)GGAAG intron-variant
rs541989802 -- 173,611,635(+) AGGAA(A/G)GTACA intron-variant
rs542211375 -- 173,613,295(+) TTATA(C/T)GCACC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for BOD1 Gene

Variant ID Type Subtype PubMed ID
esv34083 CNV Loss 18971310
esv2145234 CNV Deletion 18987734
esv2731116 CNV Deletion 23290073
esv2184384 CNV Deletion 18987734

Relevant External Links for BOD1 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for BOD1 Gene

Disorders for BOD1 Gene

Relevant External Links for BOD1

Genetic Association Database (GAD)

No disorders were found for BOD1 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships and Genatlas for BOD1 Gene

Publications for BOD1 Gene

  1. Bod1, a novel kinetochore protein required for chromosome biorientation. (PMID: 17938248) Porter I.M. … Swedlow J.R. (J. Cell Biol. 2007) 2 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  5. Hundreds of variants clustered in genomic loci and biological pathways affect human height. (PMID: 20881960) Lango Allen H. … Hirschhorn J.N. (Nature 2010) 3

Products for BOD1 Gene

Sources for BOD1 Gene

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