BNIP3L Gene
protein-coding GIFtS: 61
GCID: GC08P026240
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|
BCL2/adenovirus E1B 19kDa interacting protein 3-like(Previous name: BCL2/adenovirus E1B 19kD-interacting protein 3-like )
| |
Aliases
for BNIP3L gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| BCL2/Adenovirus E1B 19kDa Interacting Protein 3-Like1 2 | | Nix1 | | NIX2 3 5 | | BCL2/Adenovirus E1B 19kD-Interacting Protein 3-Like1 | | BNIP3a1 2 | | BCL2/Adenovirus E1B 19 KDa Protein-Interacting Protein 3-Like2 | | Adenovirus E1B19K-Binding Protein B52 3 | | BCL2/Adenovirus E1B 19-Kd Protein-Interacting Protein 3a2 | | NIP3L2 3 | | BNIP3A3 | | BCL2/Adenovirus E1B 19 KDa Protein-Interacting Protein 3A2 3 | | BNIP3H3 | | NIP3-Like Protein X2 3 | | |
Export aliases for BNIP3L gene to outside databasesPrevious GC identifers: GC08P026013 GC08P026594 GC08P026262 GC08P026296 GC08P024785 |
Summaries
for BNIP3L gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for BNIP3L:
This gene is a member of the BCL2/adenovirus E1B 19 kd-interacting protein (BNIP) family. It interacts with the E1B 19kDa protein, which protects cells from virally-induced cell death. The encoded protein also interacts with E1B 19kDa-like sequences of BCL2, another apoptotic protector. This protein counteracts the apoptotic inducer BNIP3 and mayplay a role in tumor suppression. (provided by RefSeq, Mar 2011)
UniProtKB/Swiss-Prot: BNI3L_HUMAN, O60238Function: Induces apoptosis. Interacts with viral and cellular anti-apoptosis proteins. Can overcome the suppressorsBCL-2 and BCL-XL, although high levels of BCL-XL expression will inhibit apoptosis. Inhibits apoptosis induced byBNIP3. Involved in mitochondrial quality control via its interaction with SPATA18/MIEAP: in response to mitochondrialdamage, participates to mitochondrial protein catabolic process (also named MALM) leading to the degradation ofdamaged proteins inside mitochondria. The physical interaction of SPATA18/MIEAP, BNIP3 and BNIP3L/NIX at themitochondrial outer membrane regulates the opening of a pore in the mitochondrial double membrane in order to mediatethe translocation of lysosomal proteins from the cytoplasm to the mitochondrial matrix. May function as a tumorsuppressor
Gene Wiki entry for BNIP3L
|
Genomic Views
for BNIP3L gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000008.10 NC_018919.1 NT_167187.1
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the BNIP3L gene promoter:
PPAR-gamma1 Sp1 AP-1 ATF-2 PPAR-gamma2 c-Jun
Other transcription factors
Search SABiosciences Chromatin IP Primers for BNIP3L
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat BNIP3L |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 8p21 Ensembl cytogenetic band: 8p21.2 HGNC cytogenetic band: 8p21BNIP3L Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 8 GeneLoc Exon Structure GeneLoc location for GC08P026240: view genomic region
(about GC identifiers)
Start:
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26,240,414 bp from pter |
End:
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26,363,152 bp from pter |
Size:
|
122,739 bases |
Orientation:
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plus strand |
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Proteins
for BNIP3L gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: BNI3L_HUMAN, O60238 (See
protein sequence)Recommended Name: BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like Size: 219 amino acids; 23930 Da
Subunit: Self-associates. Interacts with BNIP3 and STEAP3. Interacts with human adenovirus-2 E1B 19 kDa protein.Interacts (via BH3 domain) with SPATA18 (via coiled-coil domains)
Subcellular location: Nucleus envelope. Endoplasmic reticulum. Mitochondrion outer membrane. Membrane; Single-passmembrane protein (Potential). Note=Colocalizes with SPATA18 at the mitochondrion outer membrane
Sequence caution: Sequence=CAI46217.1; Type=Erroneous termination; Positions=122; Note=Translated as Glu;
Secondary accessions: Q5JW63 Q8NF87Explore the universe of human proteins at neXtProt for BNIP3L: NX_O60238
Post-translational modifications:
Undergoes progressive proteolysis to an 11 kDa C-terminal fragment, which is blocked by the proteasome inhibitorlactacystin1
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_O60238
BNIP3L Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_004322.1
ENSEMBL proteins: ENSP00000370003 ENSP00000428919 ENSP00000429171 ENSP00000429698 ENSP00000428597 ENSP00000429851
Human Recombinant Protein Products:
Gene Ontology (GO): 5/7 cellular component terms (GO ID links to tree view) (see all 7): About this table
BNIP3L for ontologies About GeneDecksing
BNIP3L Antibody Products:
Assay Products for BNIP3L: |
Protein
Domains /
Families
for BNIP3L gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
BNIP3L for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry O60238ProtoNet protein and cluster: O60238 1 Blocks protein family: IPB010548 BNIP3
UniProtKB/Swiss-Prot: BNI3L_HUMAN, O60238Similarity: Belongs to the NIP3 family |
Function
for BNIP3L gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: BNI3L_HUMAN, O60238Function: Induces apoptosis. Interacts with viral and cellular anti-apoptosis proteins. Can overcome the suppressorsBCL-2 and BCL-XL, although high levels of BCL-XL expression will inhibit apoptosis. Inhibits apoptosis induced byBNIP3. Involved in mitochondrial quality control via its interaction with SPATA18/MIEAP: in response to mitochondrialdamage, participates to mitochondrial protein catabolic process (also named MALM) leading to the degradation ofdamaged proteins inside mitochondria. The physical interaction of SPATA18/MIEAP, BNIP3 and BNIP3L/NIX at themitochondrial outer membrane regulates the opening of a pore in the mitochondrial double membrane in order to mediatethe translocation of lysosomal proteins from the cytoplasm to the mitochondrial matrix. May function as a tumorsuppressor Genatlas biochemistry entry for BNIP3L:BCL2/adenovirus E1B,interacting 3-like,proapoptotic,inhibiting growth of cancer cells,widely expressed (see TSG8A) andexpressed in target of the mitochondria,when inducing apoptosis
Clone
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OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for BNIP3L
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
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Synthesis Service for BNIP3L | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat BNIP3L |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for BNIP3L |
Gene Ontology (GO): 5 molecular function terms (GO ID links to tree view): About this table
BNIP3L for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for BNIP3L:
Animal Models:
Mouse knock-outs for BNIP3L: Bnip3ltm1Ney Bnip3ltm1.1Gwd
8 MGI mutant phenotypes (inferred from 4 alleles ) (MGI details for Bnip3l):
BNIP3L for phenotypes About GeneDecksing
|
Pathways & Interactions
for BNIP3L gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Apoptosis and Autophagy | | | 2 | Direct p53 effectors | | | 3 | Selected targets of p53 | | | 4 | Apoptosis Modulation and Signaling | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1 EMD Millipore Pathway for BNIP3L
1 
Cell Signaling Technology (CST) Pathway for BNIP3L
2  BioSystems Pathways for BNIP3L
BNIP3L for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for BNIP3L
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/38 Interacting proteins for BNIP3L (O602381, 2, 3 ENSP000003700034) via UniProtKB, MINT, STRING, and/or I2D (see all 38)| Interactant | Interaction Details |
|---|
| GeneCard | External ID(s) |
|---|
| DOK5 | Q9P1042, 3, ENSP000002625934 | MINT-66031 I2D:
score=5 STRING: ENSP00000262593 | | BCL2 | P104151, 3, ENSP000003296234 | EBI-849893,EBI-77694 I2D:
score=4 STRING: ENSP00000329623 | | RINT1 | Q6NUQ12, 3, ENSP000002577004 | MINT-64660 I2D:
score=4 STRING: ENSP00000257700 | | GBP2 | P324562, 3, ENSP000003594974 | MINT-8249608 I2D:
score=2 STRING: ENSP00000359497 | | BAD | Q929341, 3, ENSP000003091034 | EBI-849893,EBI-700771 I2D:
score=1 STRING: ENSP00000309103 |
About this table
Gene Ontology (GO): 5/9 biological process terms (GO ID links to tree view) (see all 9): About this table
BNIP3L for ontologies About GeneDecksing
|
Drugs & Compounds
for BNIP3L gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for BNIP3L
Search CenterWatch for drugs/clinical trials and news about BNIP3L / BNI3L
|
Transcripts
for BNIP3L gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for BNIP3L gene: NM_004331.2 Unigene Cluster for BNIP3L: BCL2/adenovirus E1B 19kDa interacting protein 3-like Hs.131226 [show with all ESTs]Unigene Representative Sequence: AF3704577 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000380629(uc003xex.1 uc010luh.1 uc010lui.1 uc003xey.2)
ENST00000520077 ENST00000523949 ENST00000523515 ENST00000520409 ENST00000518611
ENST00000521254
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for BNIP3L (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for BNIP3L
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: BNIP3L (NM_004331) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for BNIP3L | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat BNIP3L |
Additional cDNA sequence: AB004788.1 AF060922.1 AF067396.1 AF079221.1 AF370457.1 AF452712.2 AF536326.1 AK290213.1 AK300286.1 AK300727.1 AK307195.1 AK315870.1 AK316315.1 AL132665.1 BC001559.1 BC009603.1 BT019500.1 BT019501.1 CR456701.1 24/28 DOTS entries (see all 28): DT.100875672 DT.101968353 DT.75101763 DT.100678973 DT.100810182 DT.446546 DT.99944390 DT.97807005 DT.121481886 DT.121482091 DT.101971536 DT.121482024 DT.95167586 DT.99977619 DT.121481889 DT.95193355 DT.115466 DT.95238563 DT.100678969 DT.100696071 DT.121481951 DT.65284807 DT.92016057 DT.100744572 24/770 AceView cDNA sequences (see all 770): AA283080 CB306845 AA745623 AA479305 BQ003519 CA425049 AW273268 BF064273 AF452712 BU736119 CA425822 W24294 BM980344 BG576924 CA950525 BQ640049 AA988969 AW024831 CB068825 AA382068 CB243519 CA435978 BM984365 BU655963
GeneLoc Exon Structure
|
Expression
for BNIP3L gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| BNIP3L expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TATAACTTGT
About this image
See BNIP3L Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for BNIP3L
SOURCE GeneReport for Unigene cluster: Hs.131226
SABiosciences Expression via Pathway-Focused PCR Arrays including BNIP3L:
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for BNIP3L
Browse OriGene validated miRNA SYBR primer pairs
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Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for BNIP3L |
Orthologs
for BNIP3L gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for BNIP3L gene from 5/17 species (see all 17) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
BNIP3L1 |
BCL2/adenovirus E1B 19kDa interacting protein 3-like |
80.77(n)
84.13(a) |
|
419522 NM_001030885.1 NP_001026056.1 |
lizard
(Anolis carolinensis) |
Reptilia |
BNIP3L6 |
-- |
82(a) |
1 ↔ 1 |
GL343445.1(594165-599327) |
African clawed frog
(Xenopus laevis) |
Amphibia |
Xl.197702 |
Xenopus laevis transcribed sequence with moderate similarity more |
79.06(n) |
|
BU915724.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
wufb52b032 |
Transcribed sequence with moderate similarity to protein more |
77.5(n) |
|
57045247 |
fruit fly
(Drosophila melanogaster) |
Insecta |
CG50596 |
-- |
18(a) |
1 → many |
3L(20507698-20512493) |
ENSEMBL Gene Tree for BNIP3L (if available)
TreeFam Gene Tree for BNIP3L (if available) |
Paralogs
for BNIP3L gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for BNIP3L gene
- BNIP32
1 SIMAP similar gene for BNIP3L using alignment to 5 protein entries: BNI3L_HUMAN (see all proteins):BNIP3
BNIP3L for paralogs About GeneDecksing
5 Pseudogenes.org Pseudogenes for BNIP3L
PGOHUM00000258718 PGOHUM00000234547 PGOHUM00000259668 PGOHUM00000259765 PGOHUM00000240656
|
Genomic Variants
for BNIP3L gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 8 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for BNIP3L (26240414 - 26363152 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for BNIP3L: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing BNIP3L |
|
Disorders
/ Diseases
for BNIP3L gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
BNIP3L for disorders About GeneDecksing
OMIM gene information: 605368
OMIM disorders: --
13  diseases for BNIP3L: About MalaCardsglossopharyngeal neuralgia ductal carcinoma in situ hellp syndrome acute pancreatitis
oral cancer hepatocellular carcinoma colorectal cancer lung cancer
carcinoma prostate cancer pancreatitis hypoxia
prostatitis
1 disease from the University of Copenhagen DISEASES database for BNIP3L:Visual epilepsy 3 Novoseek disease relationships for BNIP3L gene About this table
Human Genome Epidemiology (HuGE) Navigator: BNIP3L (2 documents)
Export disorders for BNIP3L gene to outside databases
|
Publications
for BNIP3L gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for BNIP3L gene, integrated from 9 sources (see all 50):
(articles sorted by number of sources associating them with BNIP3L) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Isolation, mapping, and functional analysis of a novel human cDNA (BNIP3L) encoding a protein homologous to human NIP3. (PubMed id 9523198)1, 2, 3, 9 Matsushima M.... Nakamura Y. (1998)
- Nix and Nip3 form a subfamily of pro-apoptotic mitochondrial proteins. (PubMed id 9867803)1, 2, 9 Chen G.... Greenberg A. (1999)
- The proapoptotic factor Nix is coexpressed with Bcl-xL during terminal erythroid differentiation. (PubMed id 12663450)1, 2, 9 Aerbajinai W.... Miller J.L. (2003)
- Mieap, a p53-inducible protein, controls mitochondrial quality by repairing or eliminating unhealthy mitochondria. (PubMed id 21264228)1, 2 Kitamura N.... Arakawa H. (2011)
- Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (2006)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- The p53-inducible TSAP6 gene product regulates apoptosis and the cell cycle and interacts with Nix and the Myt1 kinase. (PubMed id 12606722)1, 2 Passer B.J....Telerman A. (2003)
- BNIP3alpha: a human homolog of mitochondrial proapoptotic protein BNIP3. (PubMed id 9973195)1, 3 Yasuda M....Chinnadurai G. (1999)
- A novel adenovirus E1B19K-binding protein B5 inhibits apoptosis induced by Nip3 by forming a heterodimer through the C-terminal hydrophobic region. (PubMed id 10381623)1, 2 Ohi N.... Nakajima T. (1999)
- [Expression and structure of BNIP3L in lung cancer] (PubMed id 14720367)1, 9 Sun J.L....Chen Z.C. (2004)
|
External Searches for BNIP3L gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing BNIP3L gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing BNIP3L gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing BNIP3L gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
|
About This Section
| Patent Information for BNIP3L gene:
Search GeneIP for patents involving BNIP3L
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for BNIP3L gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
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| | |  | OriGene Antibodies for BNIP3L | | OriGene shRNA RFP for BNIP3L | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for BNIP3L | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for BNIP3L | | | OriGene Protein Over-expression Lysate for BNIP3L | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for BNIP3L | | OriGene 3'-UTR Clone for BNIP3L | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for BNIP3L | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for BNIP3L | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for BNIP3L | | OriGene Custom Protein Services for BNIP3L | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat BNIP3L | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing BNIP3L | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat BNIP3L | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat BNIP3L | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat BNIP3L | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat BNIP3L |
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| | Antibodies & Assays for BNIP3L |
| | | | Search Tocris compounds for BNIP3L |
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 | | | BNIP3L Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for BNIP3L |
|  |  |  | | | | ThermoFisher Antibodies for BNIP3L |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat BNIP3L |
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