Aliases for BMPER Gene
External Ids for BMPER Gene
This gene encodes a secreted protein that interacts with, and inhibits bone morphogenetic protein (BMP) function. It has been shown to inhibit BMP2- and BMP4-dependent osteoblast differentiation and BMP-dependent differentiation of the chondrogenic cells. Mutations in this gene are associated with a lethal skeletal disorder, diaphanospondylodysostosis. [provided by RefSeq, Dec 2011]
GeneCards Summary for BMPER Gene
BMPER (BMP Binding Endothelial Regulator) is a Protein Coding gene. Diseases associated with BMPER include diaphanospondylodysostosis and spondylocostal dysostosis. An important paralog of this gene is OTOGL.
UniProtKB/Swiss-Prot for BMPER Gene
Inhibitor of bone morphogenetic protein (BMP) function, it may regulate BMP responsiveness of osteoblasts and chondrocytes.