Aliases for BMP6 Gene
External Ids for BMP6 Gene
Previous HGNC Symbols for BMP6 Gene
Previous GeneCards Identifiers for BMP6 Gene
The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. Based on its expression early in embryogenesis, the BMP encoded by this gene has a proposed role in early development. In addition, the fact that this BMP is closely related to BMP5 and BMP7 has lead to speculation of possible bone inductive activity. [provided by RefSeq, Jul 2008]
GeneCards Summary for BMP6 Gene
BMP6 (Bone Morphogenetic Protein 6) is a Protein Coding gene. Diseases associated with BMP6 include bone marrow necrosis and hypertrophic scars. Among its related pathways are Apoptotic Pathways in Synovial Fibroblasts and ERK Signaling. GO annotations related to this gene include protein heterodimerization activity and growth factor activity. An important paralog of this gene is BMP2.
UniProtKB/Swiss-Prot for BMP6 Gene
Induces cartilage and bone formation.