Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 
or upload a file of gene symbols


Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

BMP2K Gene

protein-coding   GIFtS: 54
GCID: GC04P079697

BMP2 inducible kinase

 Explore 9 diseases affiliated with
BMP2K via our new
 Human Malady Compendium 
Biological research products
for BMP2K
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
BMP2 Inducible Kinase1 2
BIKe1 3
BIKE2 3
EC 2.7.11.13 8
DKFZp434K06141
BMP-2-Inducible Protein Kinase2

External Ids:    HGNC: 180411   Entrez Gene: 555892   Ensembl: ENSG000001387567   UniProtKB: Q9NSY13   

Export aliases for BMP2K gene to outside databases

Previous GC identifers: GC04P080090 GC04P080155 GC04P080054 GC04P079916 GC04P075443


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for BMP2K:
This gene is the human homolog of mouse BMP-2-inducible kinase. Bone morphogenic proteins (BMPs) play a key role in
skeletal development and patterning. Expression of the mouse gene is increased during BMP-2 induced differentiation
and the gene product is a putative serine/threonine protein kinase containing a nuclear localization signal.
Therefore, the protein encoded by this human homolog is thought to be a protein kinase with a putative regulatory role
in attenuating the program of osteoblast differentiation. Two transcript variants encoding different isoforms have
been found for this gene. (provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: BMP2K_HUMAN, Q9NSY1
Function: May be involved in osteoblast differentiation

Gene Wiki entry for BMP2K


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000004.11  NC_018915.1  NT_016354.19  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the BMP2K gene promoter:
         Oct-B1   HFH-3   Max1   FOXI1   S8   c-Myc   En-1   ATF6   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidBMP2K promoter sequence
   Search SABiosciences Chromatin IP Primers for BMP2K

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat BMP2K


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 4q21.21   Ensembl cytogenetic band:  4q21.21   HGNC cytogenetic band: 4q21.21

BMP2K Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
BMP2K gene location

GeneLoc information about chromosome 4         GeneLoc Exon Structure

GeneLoc location for GC04P079697:  view genomic region     (about GC identifiers)

Start:
79,697,496 bp from pter      End:
79,837,526 bp from pter
Size:
140,031 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: BMP2K_HUMAN, Q9NSY1 (See protein sequence)
Recommended Name: BMP-2-inducible protein kinase  
Size: 1161 amino acids; 129172 Da
Subcellular location: Nucleus
Secondary accessions: O94791 Q8IYF2 Q8N2G7 Q8NHG9 Q9NTG8
Alternative splicing: 3 isoforms:  Q9NSY1-1   Q9NSY1-2   Q9NSY1-3   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for BMP2K: NX_Q9NSY1

Post-translational modifications:

  • Autophosphorylated (By similarity)1
  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q9NSY1

  • 4/9 DME Specific Peptides for BMP2K (Q9NSY1) (see all 9)
     DNFSKLT  VWEVLILM  FTIPDNSRYS  DIWALGCLLYKL 

    BMP2K Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins (2 alternative transcripts): 
    NP_060063.2  NP_942595.1  

    ENSEMBL proteins: 
     ENSP00000373662   ENSP00000421768   ENSP00000424668   ENSP00000334836  

    Human Recombinant Protein Products: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    OriGene Purified Protein: BMP2K
    OriGene Protein Over-expression Lysate: BMP2K
    OriGene Custom Protein Services for BMP2K 
    GenScript Custom Purified and Recombinant Proteins Services for BMP2K
    Novus Biologicals BMP2K Proteins
    Novus Biologicals BMP2K Lysate
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for BMP2K

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA--
    GO:0005730NOT nucleolus IDA--


    BMP2K for ontologies           About GeneDecksing



    BMP2K Antibody Products: 
    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for BMP2K 
    GenScript Custom Superior Antibodies Services for BMP2K
    Novus Biologicals BMP2K Antibodies
    Search for Antibodies for BMP2K at Abcam  
    Uscn Antibodies for BMP2K
    ThermoFisher Antibodies for BMP2K

    Assay Products for BMP2K: 
    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Immunoassay Development
    Browse OriGene Fluorogenic Cell Assay Kits
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for BMP2K
    Browse Enzo Life Sciences for kits & assays
    Uscn ELISAs and CLIAs for BMP2K


    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    BMP2K for domains           About GeneDecksing

    4 InterPro domains/families:
     IPR026105 BMP-2-ind_kinase
     IPR011009 Kinase-like_dom
     IPR008271 Ser/Thr_kinase_AS
     IPR000719 Prot_kinase_cat_dom

    Graphical View of Domain Structure for InterPro Entry Q9NSY1

    ProtoNet protein and cluster: Q9NSY1

    UniProtKB/Swiss-Prot: BMP2K_HUMAN, Q9NSY1
    Similarity: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family
    Similarity: Contains 1 protein kinase domain


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: BMP2K_HUMAN, Q9NSY1
    Function: May be involved in osteoblast differentiation
    Catalytic activity: ATP + a protein = ADP + a phosphoprotein

    Enzyme Number (IUBMB): EC 2.7.11.11 2

    miRNA
    Products:
        
    OriGene 3'-UTR Clone (see all 2): BMP2K
    Browse MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat BMP2K
    3 QIAGEN miScript miRNA Assays for microRNAs that regulate BMP2K:
    hsa-miR-186 hsa-miR-3143 hsa-miR-105
    SwitchGear 3'UTR luciferase reporter plasmidBMP2K 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for BMP2K (see all 4)
    OriGene shRNA RFP: BMP2K
    OriGene siRNA: BMP2K
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat BMP2K

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for BMP2K

    Clone
    Products:
         
    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for BMP2K (see all 3)
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for BMP2K (see all 2)
    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector (see all 2): BMP2K (NM_017593)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for BMP2K
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat BMP2K 

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for BMP2K
    Search LifeMap BioReagents cell lines for BMP2K

    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for BMP2K

    Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004672protein kinase activity ----
    GO:0004674protein serine/threonine kinase activity IEA--
    GO:0005524ATP binding IEA--
    GO:0019208phosphatase regulator activity IEA--


    BMP2K for ontologies           About GeneDecksing


    3 GenomeRNAi human phenotypes for BMP2K:
     Decreased substrate adherent c  Decreased telomerase activity  Increased TP53 protein express 


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for BMP2K

    STRING Interaction Network Preview (showing 5 interactants - click image to see 6)

    5/8 Interacting proteins for BMP2K (Q9NSY13 ENSP000003348364) via UniProtKB, MINT, STRING, and/or I2D (see all 8)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    MBPP026863, ENSP000003482734I2D: score=1 STRING: ENSP00000348273
    TERF1P542743, ENSP000002766034I2D: score=1 STRING: ENSP00000276603
    EPS15P425663, ENSP000003607984I2D: score=1 STRING: ENSP00000360798
    KDM5BQ9UGL13, ENSP000003562344I2D: score=1 STRING: ENSP00000356234
    TERF2Q155543, ENSP000002549424I2D: score=1 STRING: ENSP00000254942
    About this table

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006468protein phosphorylation ----
    GO:0030500regulation of bone mineralization IEA--


    BMP2K for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for BMP2K

    2 HMDB Compounds for BMP2K    About this table
    CompoundSynonyms CAS #PubMed Ids
    ADPadenosindiphosphorsaeure (see all 8)58-64-0--
    Adenosine triphosphate5'-(tetrahydrogen triphosphate) Adenosine (see all 24)56-65-5--
    Search CenterWatch for drugs/clinical trials and news about BMP2K 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for BMP2K gene (2 alternative transcripts): 
    NM_017593.3  NM_198892.1  

    Unigene Cluster for BMP2K:

    BMP2 inducible kinase
    Hs.146551  [show with all ESTs]
    Unigene Representative Sequence: BX641162
    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000389010(uc010ijl.1) ENST00000502871(uc003hlj.3) ENST00000505725
    ENST00000515075 ENST00000502613 ENST00000507670(uc003hll.3) ENST00000335016(uc003hlk.3)


    miRNA
    Products:
         
    OriGene 3'-UTR Clone (see all 2): BMP2K
    Browse OriGene MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat BMP2K
    3 QIAGEN miScript miRNA Assays for microRNAs that regulate BMP2K:
    hsa-miR-186 hsa-miR-3143 hsa-miR-105
    SwitchGear 3'UTR luciferase reporter plasmidBMP2K 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for BMP2K (see all 4)
    OriGene shRNA RFP: BMP2K
    OriGene siRNA: BMP2K
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat BMP2K
    Clone
    Products:
         
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for BMP2K (see all 3)
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for BMP2K (see all 2)
    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector (see all 2): BMP2K (NM_017593)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for BMP2K
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat BMP2K 
    Primer
    Products:
        
    OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for BMP2K
    Browse OriGene validated miRNA SYBR primer pairs
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat BMP2K
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat BMP2K
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat BMP2K

    Additional cDNA sequence: 

    AB015331.1 AK021725.1 AK075278.1 AK094144.1 AK292147.1 AL137275.1 AL137661.1 BC036021.1 
    BX641162.1 

    10 DOTS entries:

    DT.310672  DT.100746794  DT.121256274  DT.121256245  DT.86839226  DT.70100355  DT.121256227  DT.75183646 
    DT.92047207  DT.97826435 

    24/130 AceView cDNA sequences (see all 130):

    AL137661 AA491136 AA343337 BM477048 AA490949 AI800989 BM710805 AI369613 
    AA491060 BX104243 AL137275 AA926798 AK075278 AW300795 AI939552 BG776990 
    AI472106 AW070638 BX641162 BM667636 AB015331 AK094144 CA446589 NM_017593 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for BMP2K    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7a · 7b ^ 8a · 8b ^ 9 ^ 10a · 10b ^ 11a · 11b ^ 12a · 12b ^ 13 ^ 14 ^ 15 ^ 16
    SP1:                                      -           -                                   -                                       
    SP2:                                                  -           -                                                               
    SP3:                                                                                                                              
    SP4:                                                              -                                                               


    ECgene alternative splicing isoforms for BMP2K

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    BMP2K expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: ATTTGGGGTT

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image
    See BMP2K Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for BMP2K

    SOURCE GeneReport for Unigene cluster: Hs.146551
        SABiosciences Custom PCR Arrays for BMP2K
    Primer
    Products:
    OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for BMP2K
    Browse OriGene validated miRNA SYBR primer pairs
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat BMP2K
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat BMP2K
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat BMP2K
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for BMP2K

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for BMP2K gene from 7/24 species (see all 24)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Bmp2k1 , 5 BMP2 inducible kinase1, 5 84.22(n)1
    84.81(a)1
      5 (47.29 cM)5
    1407801  NM_080708.11  NP_542439.11 
     969976895 
    chicken
    (Gallus gallus)
    Aves BMP2K1 BMP2 inducible kinase 72.54(n)
    74.4(a)
      422578  XM_420537.3  XP_420537.2 
    lizard
    (Anolis carolinensis)
    Reptilia BMP2K6
    --
    68(a)
    1 ↔ 1
    5(145419936-145450165)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.93352 Xenopus laevis transcribed sequence with weak similarity more 78.77(n)    BJ097576.1 
    zebrafish
    (Danio rerio)
    Actinopterygii bmp2k1 BMP2 inducible kinase 63.22(n)
    62.22(a)
      494101  NM_001193540.1  NP_001180469.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta Nak6
    Numb-associated kinase
    17(a)
    1 → many
    2L(18957900-18968721)
    worm
    (Caenorhabditis elegans)
    Secernentea sel-56
    Suppressor/Enhancer of Lin-12 family member (sel-5...
    20(a)
    1 → many
    III(4571721-4578405)


    ENSEMBL Gene Tree for BMP2K (if available)
    TreeFam Gene Tree for BMP2K (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for BMP2K gene
    AAK12  
    5 SIMAP similar genes for BMP2K using alignment to 4 protein entries:     BMP2K_HUMAN (see all proteins):
    BMP2KL    AAK1    GAK    DKFZp564L2416    NUAK1

    BMP2K for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for BMP2K
    PGOHUM00000262171


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 1 variation for BMP2K
         1 Indel: 68755
    Human Gene Mutation Database (HGMD): BMP2K
    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing BMP2K
    DNA2.0 Custom Variant and Variant Library Synthesis for BMP2K

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    BMP2K for disorders           About GeneDecksing

    9 diseases for BMP2K:    About MalaCards
    internuclear ophthalmoplegia    vaginal discharge    ulnar neuropathy    ophthalmoplegia
    myopia    neuropathy    vaginitis    osteoporosis
    malaria

    Human Genome Epidemiology (HuGE) Navigator: BMP2K (3 documents)

    Export disorders for BMP2K gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for BMP2K gene, integrated from 9 sources (see all 25):
    (articles sorted by number of sources associating them with BMP2K)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (2006)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    4. Selection system for genes encoding nuclear-targeted proteins. (PubMed id 9853615)1, 2 Ueki N.... Muramatsu M.-A. (1998)
    5. A novel genetic variant of BMP2K contributes to high myopia. (PubMed id 19927351)1, 9 Liu H.P....Tsai F.J. (2009)
    6. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
    7. Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. (PubMed id 20068231)2 Olsen J.V....Mann M. (2010)
    8. The protein network surrounding the human telomere re peat binding factors TRF1, TRF2, and POT1. (PubMed id 20811636)1 Giannone R.J....Liu Y. (2010)
    9. The PcG protein hPc2 interacts with the N-terminus of histone demethylase JARID1B and acts as a transcriptional co-repressor. (PubMed id 19336002)1 Zhou W....Zhang L. (2009)
    10. Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. (PubMed id 19690332)2 Mayya V.... Han D.K. (2009)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 55589 HGNC: 18041 AceView: BMP2K Ensembl:ENSG00000138756 euGenes: HUgn55589
    ECgene: BMP2K H-InvDB: BMP2K

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for BMP2K Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for BMP2K gene:
    Search GeneIP for patents involving BMP2K

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
    In Situ Hybridization Assays from
    Advanced Cell Diagnostics
    About This Section

     
     EMD Millipore Custom Antibody & Bulk Services
     EMD Millipore Preclinical / Clinical Development Services
     EMD Millipore Immunoassay Services
     EMD Millipore Target Screening & Profiling Services

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Kinase Activity Assays/Reagents  
     Browse ELISpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Multiplex/Array Assay Kits/Reagents  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Phosphatase Activity Assays/Reagents   Browse Recombinant/Natural Proteins  
     Browse OriGene Antibodies   OriGene shRNA RFP for BMP2K  
     OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for BMP2K   OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for BMP2K  
     OriGene Protein Over-expression Lysate for BMP2K   Browse OriGene Fluorogenic Cell Assay Kits  
     OriGene siRNA for BMP2K   OriGene 3'-UTR Clone for BMP2K  
     OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for BMP2K   OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for BMP2K  
     Browse OriGene GFP tagged cDNA clones in CMV expression vector   Browse OriGene MicroRNA Expression Plasmids  
     Browse OriGene basic RS shRNAs   Browse OriGene validated miRNA SYBR primer pairs  
     OriGene Purified Protein for BMP2K   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for BMP2K   OriGene Custom Protein Services for BMP2K  
     OriGene Custom Immunoassay Development  

     
     
     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat BMP2K
     QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing BMP2K
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat BMP2K
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat BMP2K
     QIAGEN QuantiFast Probe-based Assays in human, mouse, rat BMP2K
     QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat BMP2K
     GenScript Custom Purified and Recombinant Proteins Services for BMP2K GenScript cDNA clones with any tag delivered in your preferred vector for BMP2K
     GenScript Custom Assay Services for BMP2K GenScript Custom Superior Antibodies Services for BMP2K
     GenScript Custom overexpressing Cell Line Services for BMP2K CloneReady with Over 120,000 Genes
     Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
     Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
     Custom Peptide Services
     Search for Antibodies & Assays

     Regulatory tfbs in BMP2K promoter
     Search Chromatin IP Primers for BMP2K
     RT2 qPCR Primer Assay in human, mouse, rat BMP2K
     Search GNC Networks for BMP2K
     SABiosciences Custom PCR Arrays for BMP2K
     Search Tocris compounds for BMP2K
     Browse Sino Biological Proteins and Antibodies
     Browse Sino Biological cDNA Clones
     Antibodies/Proteins Production Services
     Rabbit Monoclonal Antibody Platform
     Bulk Purchasing
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Tissue Slides
     BMP2K antibodies
     BMP2K proteins
     BMP2K lysates
     Search for Antibodies for BMP2K at Abcam
     See all of Abcam's Antibodies, Kits and Proteins for BMP2K
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins




     BMP2K Proteins, Antibodies, CLIAs, and ELISAs
     Search LifeMap BioReagents cell lines for BMP2K
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for BMP2K
     SwitchGear 3'UTR luciferase reporter plasmids for BMP2K
     SwitchGear Promoter luciferase reporter plasmids for BMP2K
     ThermoFisher Antibodies for BMP2K
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat BMP2K
           
    GeneCards Homepage - Last full update: 18 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013

    View Random Gene

    Category
    VWF
    (GIFTS: 73)
    von Willebrand factor
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      BMP2K gene at Home site.
    hostname: 356977-web1.xennexinc.com index build: 100 solr: 1.4