Aliases for BMP15 Gene
External Ids for BMP15 Gene
Previous GeneCards Identifiers for BMP15 Gene
The protein encoded by this gene is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The transforming growth factor-beta superfamily includes large families of growth and differentiation factors. It is thought that this protein may be involved in oocyte maturation and follicular development as a homodimer or by forming heterodimers with a related protein, Gdf9. Defects in this gene are the cause of ovarian dysgenesis 2.[provided by RefSeq, Sep 2009]
GeneCards Summary for BMP15 Gene
BMP15 (Bone Morphogenetic Protein 15) is a Protein Coding gene. Diseases associated with BMP15 include Ovarian Dysgenesis 2 and 46,Xx Testicular Disorder Of Sex Development. Among its related pathways are ERK Signaling and TGF-Beta Pathway. GO annotations related to this gene include cytokine activity and transforming growth factor beta receptor binding. An important paralog of this gene is GDF10.
UniProtKB/Swiss-Prot for BMP15 Gene
May be involved in follicular development. Oocyte-specific growth/differentiation factor that stimulates folliculogenesis and granulosa cell (GC) growth.