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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

BLZF1 Gene

protein-coding   GIFtS: 57
GCID: GC01P169337

basic leucine zipper nuclear factor 1

 Explore 104 diseases affiliated with
BLZF1 via our new
 Human Malady Compendium 
Biological research products
for BLZF1
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
Basic Leucine Zipper Nuclear Factor 11 2 3     Golgin-452
JEM-11 2 3     JEM-1s2
JEM12 3     Cytoplasmic Protein2
P45 Basic Leucine-Zipper Nuclear Factor2 3     JEM-1short Protein2
GOLGIN-452     

External Ids:    HGNC: 10651   Entrez Gene: 85482   Ensembl: ENSG000001174757   OMIM: 6086925   UniProtKB: Q9H2G93   

Export aliases for BLZF1 gene to outside databases

Previous GC identifers: GC01P166966 GC01P164988 GC01P166033 GC01P166524 GC01P166068 GC01P167603 GC01P140560


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: GO45_HUMAN, Q9H2G9
Function: Required for normal Golgi structure and for protein transport from the endoplasmic reticulum (ER) through the
Golgi apparatus to the cell surface

Gene Wiki entry for BLZF1


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000001.10  NC_018912.1  NT_004487.19  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the BLZF1 gene promoter:
         Bach1   STAT1   p53   STAT1beta   LUN-1   STAT1alpha   Egr-2   Sox9   ATF6   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidBLZF1 promoter sequence
   Search SABiosciences Chromatin IP Primers for BLZF1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat BLZF1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1q24   Ensembl cytogenetic band:  1q24.2   HGNC cytogenetic band: 1q24

BLZF1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
BLZF1 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01P169337:  view genomic region     (about GC identifiers)

Start:
169,337,194 bp from pter      End:
169,365,782 bp from pter
Size:
28,589 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: GO45_HUMAN, Q9H2G9 (See protein sequence)
Recommended Name: Golgin-45  
Size: 400 amino acids; 44910 Da
Subunit: Interacts with GORASP2 and with the GTP-bound form of RAB2, but not with other Golgi Rab proteins. GORASP2 and
BLZF1 form a RAB2 effector complex on medial Golgi
Subcellular location: Golgi apparatus lumen
Subcellular location: Isoform 1: Nucleus
Subcellular location: Isoform 2: Cytoplasm
Caution: Because of the presence of a potential basic motif and leucine-zipper domain, PubMed:9129147 and
PubMed:11056056 have thought that BLZF1 is a potential transcription factor. They found it localized in the nucleus,
except isoform 2, which was cytoplasmic. However, homology at several typical position for basic or hydrophobic
residues is missing
Secondary accessions: O15298 Q5T531 Q5T533 Q9GZX4
Alternative splicing: 2 isoforms:  Q9H2G9-1   Q9H2G9-2   

Explore the universe of human proteins at neXtProt for BLZF1: NX_Q9H2G9

Post-translational modifications:

  • ADP-ribosylated by tankyrase TNKS and TNKS2. Poly-ADP-ribosylated protein is recognized by RNF146, followed by
  • ubiquitination1
  • Ubiquitinated by RNF146 when poly-ADP-ribosylated, leading to its degradation1
  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q9H2G9

  • BLZF1 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_003657.1  
    ENSEMBL proteins: 
     ENSP00000356782   ENSP00000327541   ENSP00000356781   ENSP00000414668   ENSP00000404408  
    Reactome Protein details: Q9H2G9
    Human Recombinant Protein Products: 
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    Uscn Proteins for BLZF1

    Gene Ontology (GO): 5/6 cellular component terms (GO ID links to tree view) (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000139Golgi membrane IEA--
    GO:0005634nucleus NAS9129147
    GO:0005730NOT nucleolus IDA--
    GO:0005737cytoplasm NAS11056056
    GO:0005794Golgi apparatus ----


    BLZF1 for ontologies           About GeneDecksing



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    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    BLZF1 for domains           About GeneDecksing

    2 InterPro domains/families:
     IPR027095 Golgin-45
     IPR013183 Hsk3_like

    Graphical View of Domain Structure for InterPro Entry Q9H2G9

    ProtoNet protein and cluster: Q9H2G9

    UniProtKB/Swiss-Prot: GO45_HUMAN, Q9H2G9
    Domain: The tankyrase-binding motif (also named TBD) is required for interaction with tankyrase TNKS and TNKS2


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: GO45_HUMAN, Q9H2G9
    Function: Required for normal Golgi structure and for protein transport from the endoplasmic reticulum (ER) through the
    Golgi apparatus to the cell surface
    Induction: Up-regulated by retinoids

         Genatlas biochemistry entry for BLZF1:
    basic leucine zipper nuclear factor,45kDa,upregulated during retinoid-induced maturation of NB4-promyelocytic leukemia
    cells

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    Gene Ontology (GO): 5 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003677DNA binding NAS9129147
    GO:0003700sequence-specific DNA binding transcription factor activity NAS9129147
    GO:0005515protein binding ----
    GO:0019899enzyme binding IPI--
    GO:0031625ubiquitin protein ligase binding IPI--


    BLZF1 for ontologies           About GeneDecksing


    1 GenomeRNAi human phenotype for BLZF1:
     Synthetic lethal with c-Myc af 

    Animal Models:
         2 MGI mutant phenotypes (inferred from 1 allele(MGI details for Blzf1):
     limbs/digits/tail  skeleton 

    BLZF1 for phenotypes           About GeneDecksing


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1M Phase
    M Phase1.00
    Mitotic M-M/G1 phases0.88
    2Cell Cycle
    Cell Cycle1.00
    Cell Cycle, Mitotic0.84
    3Clearance of Nuclear Envelope Membranes from Chromatin
    Mitotic Prophase0.26
    Golgi Cisternae Pericentriolar Stack Reorganization0.00

    Pathway sources
    See GeneCards unified pathways
    Show all pathways


    5/6        Reactome Pathways for BLZF1 (see all 6)
        Golgi Cisternae Pericentriolar Stack Reorganization
    Mitotic Prophase
    Cell Cycle
    M Phase
    Mitotic M-M/G1 phases



    BLZF1 for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for BLZF1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 8)

    5/9 Interacting proteins for BLZF1 (Q9H2G93 ENSP000003275414) via UniProtKB, MINT, STRING, and/or I2D (see all 9)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    GORASP2Q9H8Y83, ENSP000002341604I2D: score=2 STRING: ENSP00000234160
    RAB2AP610193, ENSP000002626464I2D: score=1 STRING: ENSP00000262646
    ORC2Q134163, ENSP000002342964I2D: score=1 STRING: ENSP00000234296
    EWSR1Q018443, ENSP000003810314I2D: score=1 STRING: ENSP00000381031
    HCLS1P143173, ENSP000003201764I2D: score=1 STRING: ENSP00000320176
    About this table

    Gene Ontology (GO): 5/6 biological process terms (GO ID links to tree view) (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001558regulation of cell growth NAS9129147
    GO:0006355regulation of transcription, DNA-dependent ----
    GO:0006357regulation of transcription from RNA polymerase II promoter TAS9129147
    GO:0007030Golgi organization IDA11739401
    GO:0008283cell proliferation TAS9129147


    BLZF1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    BLZF1 for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
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    Browse Tocris compounds for BLZF1

    1 HMDB Compound for BLZF1    About this table
    CompoundSynonyms CAS #PubMed Ids
    Guanosine triphosphate5'-GTP (see all 10)86-01-1--
    10/90 Novoseek chemical compound relationships for BLZF1 gene (see all 90)    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    tyrosine 53.8 53 11215526 (7), 11341776 (2), 1825054 (1), 17964991 (1) (see all 43)
    phosphotyrosine 52.3 6 17964991 (1), 7515480 (1), 17439981 (1), 7531695 (1) (see all 6)
    n-acetylglucosamine 48.5 13 9452489 (2), 17909453 (1), 8639509 (1), 8742080 (1) (see all 12)
    threonine 42 17 19028792 (1), 19607882 (1), 20409980 (1), 17507370 (1) (see all 17)
    serine 38.1 21 11341776 (1), 19028792 (1), 19607882 (1), 20409980 (1) (see all 21)
    lumazine 33.6 3 11874879 (1), 10482294 (1)
    cycloheximide 29.8 6 9093376 (1), 1731978 (1), 2339053 (1), 8158254 (1) (see all 6)
    phosphatidylinositol 22.9 4 15187135 (1), 8382465 (1), 8822210 (1), 12837292 (1)
    mg 132 20.5 1 11172811 (1)
    retinoic acid 18 13 11215526 (2), 7488392 (1), 7716736 (1), 11580199 (1) (see all 6)

    Search CenterWatch for drugs/clinical trials and news about BLZF1 / GO45 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for BLZF1 gene: 
    NM_003666.2  

    Unigene Cluster for BLZF1:

    Basic leucine zipper nuclear factor 1
    Hs.130746  [show with all ESTs]
    Unigene Representative Sequence: U79751
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000367808(uc001gfx.2) ENST00000329281(uc009wvp.1 uc001gfy.3)
    ENST00000367807(uc001gfw.3) ENST00000420531 ENST00000426663

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    Additional cDNA sequence: 

    AF288161.1 AK223533.1 AK291725.1 AK307151.1 BC020716.1 U79751.1 

    14 DOTS entries:

    DT.453121  DT.100820040  DT.100820048  DT.97820048  DT.65288030  DT.97809884  DT.100720242  DT.121401583 
    DT.97770498  DT.100765610  DT.86849733  DT.105627  DT.121401667  DT.121401732 

    24/199 AceView cDNA sequences (see all 199):

    CR599652 BQ186102 AA737828 AA577225 BI711453 BI764470 CA413059 BQ582226 
    AL599568 AI435014 AA169606 BG621216 BM457967 BE859004 BX401251 D62974 
    BG617529 BQ549474 CR591083 NM_003666 CB160151 AL601677 BX328880 BM692501 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for BLZF1    About this scheme

    ExUns: 1a · 1b · 1c · 1d · 1e ^ 2a · 2b · 2c ^ 3a · 3b · 3c ^ 4a · 4b ^ 5 ^ 6
    SP1:                          -                 -                 -                           
    SP2:                                            -                 -                           
    SP3:                          -     -           -                                             
    SP4:                          -                 -                                             
    SP5:                          -                                                               


    ECgene alternative splicing isoforms for BLZF1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    BLZF1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: CTAGTTTTAT

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image
    See BLZF1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for BLZF1

    SOURCE GeneReport for Unigene cluster: Hs.130746

    UniProtKB/Swiss-Prot: GO45_HUMAN, Q9H2G9
    Tissue specificity: Ubiquitous. Also found in cell lines derived from several hematopoietic pathologies, such as T-cell
    leukemia, pro-B, pre-B, myeloma, and plasmacytoma cell lines, but not in Burkitt lymphoma cells

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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for BLZF1 gene from 7/20 species (see all 20)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Blzf11 , 5 basic leucine zipper nuclear factor 11, 5 83.75(n)1
    83.67(a)1
      1 (71.60 cM)5
    663521  NM_001160208.11  NP_001153680.11 
     1642898005 
    chicken
    (Gallus gallus)
    Aves BLZF11 basic leucine zipper nuclear factor 1 72.28(n)
    72.19(a)
      418371  XM_416590.3  XP_416590.1 
    lizard
    (Anolis carolinensis)
    Reptilia BLZF16
    --
    70(a)
    1 ↔ 1
    3(175652280-175660306)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.83062 Xenopus laevis transcribed sequence with weak similarity more 74.53(n)    CA987396.1 
    zebrafish
    (Danio rerio)
    Actinopterygii blzf12 Danio rerio cDNA clone MGC66280 IMAGE5411912, complete more 71.8(n)    BC055578.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG93566
    --
    21(a)
    1 ↔ 1
    3R(5228286-5229991)
    worm
    (Caenorhabditis elegans)
    Secernentea R12B2.26
    Protein R12B2.2
    23(a)
    1 ↔ 1
    III(5807007-5809162)


    ENSEMBL Gene Tree for BLZF1 (if available)
    TreeFam Gene Tree for BLZF1 (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for BLZF1 gene

    BLZF1 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for BLZF1
    PGOHUM00000247841


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/508 NCBI SNPs in BLZF1 are shown (see all 508    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs9258921,2
    C,F,O,A,--169335254(-) CTTCCT/CGGACA 3 -- int1 us2k115Minor allele frequency- C:0.29NA WA CSA EA 517
    rs1441659471,2
    --169335288(+) TCTGAG/TAGGAA 3 -- int1 us2k10--------
    rs1150184321,2
    --169335290(+) TGAGAA/GGAAAA 3 -- us2k1 int10--------
    rs1511458261,2
    --169335324(+) AGGTGG/TTAGTA 3 -- int1 us2k10--------
    rs1861187551,2
    --169335347(+) GTGGAA/CAAAAT 3 -- us2k1 int10--------
    rs1894285351,2
    --169335607(+) TGTTTC/GATATA 3 -- us2k1 int10--------
    rs1814728851,2
    --169335792(+) AAAAAC/TAACTG 3 -- us2k1 int10--------
    rs730368491,2
    C,--169335875(+) TTCTCC/TACACT 3 -- us2k1 int11Minor allele frequency- T:0.50WA 2
    rs1860001151,2
    --169335972(+) CATCAC/TGTTTA 3 -- us2k1 int10--------
    rs1490830821,2
    C,--169336121(+) GAGGG-/CCTCTG 3 -- int1 us2k10--------

    HapMap Linkage Disequilibrium report for BLZF1 (169337194 - 169365782 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 1 variation for BLZF1
         1 CNV: 65206

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    BLZF1 for disorders           About GeneDecksing

    OMIM gene information: 608692    OMIM disorders: --

    20/104 diseases for BLZF1 (see all 104):    About MalaCards
    lissencephaly x-linked    peutz-jeghers syndrome    paraneoplastic cerebellar degeneration    wiskott-aldrich syndrome
    spinal muscular atrophy    machado-joseph disease    human t-cell leukemia virus type 1    spinocerebellar ataxia type 6
    dna topoisomerase i    cerebellar degeneration    myocardial infarction    muscular atrophy
    acute myocardial infarction    soft tissue sarcoma    spinocerebellar ataxia    myofibrillar myopathy
    myasthenic syndrome    congenital myasthenic syndrome    connective tissue disease    fanconi's anemia

    1 disease from the University of Copenhagen DISEASES database for BLZF1:
    Lyme disease

    10/65 Novoseek disease relationships for BLZF1 gene (see all 65)    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    lissencephaly, x-linked 43.6 1 12223548 (1)
    paraneoplastic cerebellar degeneration 42 1 11771954 (1)
    pemphigus 28.2 1 10863179 (1)
    tumors 25.5 11 9795272 (1), 16425368 (1), 15994306 (1), 12414522 (1) (see all 11)
    neurodegenerative diseases 24.4 4 17894839 (1), 15694337 (1), 15240551 (1), 18414043 (1)
    neurodegeneration 22.8 2 19738442 (1), 20153326 (1)
    leukemia t-cell 21.7 2 7615529 (1), 18599479 (1)
    brucellosis 20.5 4 11303810 (2), 8852961 (1), 10482294 (1)
    shock 19.9 16 8655591 (1), 10865880 (1), 17663445 (1), 8886893 (1) (see all 15)
    cancer 13 5 19204029 (1), 20003713 (1), 18550844 (1), 16503970 (1) (see all 5)

    Human Genome Epidemiology (HuGE) Navigator: BLZF1 (2 documents)

    Export disorders for BLZF1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for BLZF1 gene, integrated from 9 sources (see all 491):
    (articles sorted by number of sources associating them with BLZF1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. JEM-1, a novel gene encoding a leucine-zipper nuclear factor upregulated during retinoid-induced maturation of NB4 promyelocytic leukaemia. (PubMed id 9129147)1, 2, 3 Duprez E....Lanotte M. (1997)
    2. Genomic organization of the JEM-1 (BLZF1) gene on human chromosome 1q24: molecular cloning and analysis of its promoter region. (PubMed id 11056056)1, 2, 9 Tong J.-H.... Lanotte M. (2000)
    3. A GRASP55-rab2 effector complex linking Golgi structure to membrane traffic. (PubMed id 11739401)1, 2, 9 Short B....Barr F.A. (2001)
    4. RNF146 is a poly(ADP-ribose)-directed E3 ligase that regulates axin degradation and Wnt signalling. (PubMed id 21478859)1, 2 Zhang Y.... Cong F. (2011)
    5. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (2006)
    6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    7. Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
    8. An atlas of combinatorial transcriptional regulation in mouse and man. (PubMed id 20211142)1 Ravasi T....Hayashizaki Y. (2010)
    9. Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. (PubMed id 20068231)2 Olsen J.V....Mann M. (2010)
    10. The steroid receptor RNA activator protein is recruit ed to promoter regions and acts as a transcriptional repressor. (PubMed id 20398657)1 Chooniedass-Kothari S....Leygue E. (2010)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Disorders
    Free Text  

      Query String
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    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 8548 HGNC: 1065 AceView: BLZF1 Ensembl:ENSG00000117475 euGenes: HUgn8548
    ECgene: BLZF1 H-InvDB: BLZF1

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for BLZF1 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for BLZF1 Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for BLZF1 gene:
    Search GeneIP for patents involving BLZF1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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     Regulatory tfbs in BLZF1 promoter
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