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Aliases for BLOC1S5-TXNDC5 Gene

Subcategory (RNA class) for BLOC1S5-TXNDC5 Gene

ncRNA

Quality Score for this RNA gene is

3

Aliases for BLOC1S5-TXNDC5 Gene

  • BLOC1S5-TXNDC5 Readthrough (NMD Candidate) 2 3 5
  • MUTED-TXNDC5 Readthrough (Non-Protein Coding) 2 3
  • BLOC1S5-TXNDC5 Readthrough (Non-Protein Coding) 3
  • MUTED-TXNDC5 3

External Ids for BLOC1S5-TXNDC5 Gene

Previous HGNC Symbols for BLOC1S5-TXNDC5 Gene

  • MUTED-TXNDC5

Previous GeneCards Identifiers for BLOC1S5-TXNDC5 Gene

  • GC06U902279
  • GC06M007886
  • GC06M007888

Summaries for BLOC1S5-TXNDC5 Gene

Entrez Gene Summary for BLOC1S5-TXNDC5 Gene

  • This locus represents naturally occurring read-through transcription between the neighboring MUTED (muted homolog) and TXNDC5 (thioredoxin domain containing 5) genes on chromosome 6. The read-through transcript is a candidate for nonsense-mediated mRNA decay (NMD) and is unlikely to produce a protein product. [provided by RefSeq, Dec 2010]

GeneCards Summary for BLOC1S5-TXNDC5 Gene

BLOC1S5-TXNDC5 (BLOC1S5-TXNDC5 Readthrough (NMD Candidate)) is an RNA Gene, and is affiliated with the ncRNA class. GO annotations related to this gene include isomerase activity. An important paralog of this gene is BLOC1S5.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for BLOC1S5-TXNDC5 Gene

Genomics for BLOC1S5-TXNDC5 Gene

Regulatory Elements for BLOC1S5-TXNDC5 Gene

Enhancers for BLOC1S5-TXNDC5 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
- Elite enhancer/Elite enhancer-gene association

Enhancers around BLOC1S5-TXNDC5 on UCSC Golden Path with GeneCards custom track

Promoters for BLOC1S5-TXNDC5 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around BLOC1S5-TXNDC5 on UCSC Golden Path with GeneCards custom track

Genomic Location for BLOC1S5-TXNDC5 Gene

Chromosome:
6
Start:
7,881,250 bp from pter
End:
8,064,414 bp from pter
Size:
183,165 bases
Orientation:
Minus strand

Genomic View for BLOC1S5-TXNDC5 Gene

Genes around BLOC1S5-TXNDC5 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
BLOC1S5-TXNDC5 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for BLOC1S5-TXNDC5 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for BLOC1S5-TXNDC5 Gene

Proteins for BLOC1S5-TXNDC5 Gene

  • Protein details for BLOC1S5-TXNDC5 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    H3BN57
    Recommended name:
    Protein BLOC1S5-TXNDC5
    Protein Accession:
    H3BN57

    Protein attributes for BLOC1S5-TXNDC5 Gene

    Size:
    136 amino acids
    Molecular mass:
    15343 Da
    Quaternary structure:
    No Data Available

neXtProt entry for BLOC1S5-TXNDC5 Gene

Protein Expression for BLOC1S5-TXNDC5 Gene

Post-translational modifications for BLOC1S5-TXNDC5 Gene

No Post-translational modifications

Other Protein References for BLOC1S5-TXNDC5 Gene

ENSEMBL proteins:

No data available for DME Specific Peptides for BLOC1S5-TXNDC5 Gene

Domains & Families for BLOC1S5-TXNDC5 Gene

Protein Domains for BLOC1S5-TXNDC5 Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with BLOC1S5-TXNDC5: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for BLOC1S5-TXNDC5 Gene

Function for BLOC1S5-TXNDC5 Gene

Phenotypes for BLOC1S5-TXNDC5 Gene

genes like me logo Genes that share phenotypes with BLOC1S5-TXNDC5: view

Animal Model Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for BLOC1S5-TXNDC5 Gene

Localization for BLOC1S5-TXNDC5 Gene

Gene Ontology (GO) - Cellular Components for BLOC1S5-TXNDC5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0030133 transport vesicle IEA --
GO:0031083 BLOC-1 complex IBA --
genes like me logo Genes that share ontologies with BLOC1S5-TXNDC5: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Subcellular locations from COMPARTMENTS for BLOC1S5-TXNDC5 Gene

Pathways & Interactions for BLOC1S5-TXNDC5 Gene

SuperPathways for BLOC1S5-TXNDC5 Gene

No Data Available

Interacting Proteins for BLOC1S5-TXNDC5 Gene

Gene Ontology (GO) - Biological Process for BLOC1S5-TXNDC5 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for BLOC1S5-TXNDC5 Gene

Drugs & Compounds for BLOC1S5-TXNDC5 Gene

No Compound Related Data Available

Transcripts for BLOC1S5-TXNDC5 Gene

mRNA/cDNA for BLOC1S5-TXNDC5 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for BLOC1S5-TXNDC5 Gene

No ASD Table

Relevant External Links for BLOC1S5-TXNDC5 Gene

GeneLoc Exon Structure for
BLOC1S5-TXNDC5
ECgene alternative splicing isoforms for
BLOC1S5-TXNDC5

Expression for BLOC1S5-TXNDC5 Gene

mRNA expression in normal human tissues for BLOC1S5-TXNDC5 Gene

Protein differential expression in normal tissues from HIPED for BLOC1S5-TXNDC5 Gene

This gene is overexpressed in Oral epithelium (11.7) and Tonsil (6.4).

Integrated Proteomics: protein expression in normal tissues and cell lines from MOPED for BLOC1S5-TXNDC5 Gene



Protein tissue co-expression partners for BLOC1S5-TXNDC5 Gene

genes like me logo Genes that share expression patterns with BLOC1S5-TXNDC5: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for BLOC1S5-TXNDC5 Gene

Orthologs for BLOC1S5-TXNDC5 Gene

This gene was present in the common ancestor of chordates.

Orthologs for BLOC1S5-TXNDC5 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia -- 35
  • 60 (a)
OneToMany
dog
(Canis familiaris)
Mammalia -- 35
  • 53 (a)
OneToMany
oppossum
(Monodelphis domestica)
Mammalia -- 35
  • 50 (a)
OneToMany
mouse
(Mus musculus)
Mammalia Bloc1s5 35
  • 56 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 35
  • 50 (a)
OneToMany
chimpanzee
(Pan troglodytes)
Mammalia BLOC1S5-TXNDC5 35
  • 91 (a)
OneToOne
chicken
(Gallus gallus)
Aves BLOC1S5 35
  • 40 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia -- 35
  • 41 (a)
OneToMany
zebrafish
(Danio rerio)
Actinopterygii bloc1s5 35
  • 37 (a)
OneToMany
Species where no ortholog for BLOC1S5-TXNDC5 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for BLOC1S5-TXNDC5 Gene

ENSEMBL:
Gene Tree for BLOC1S5-TXNDC5 (if available)
TreeFam:
Gene Tree for BLOC1S5-TXNDC5 (if available)

Paralogs for BLOC1S5-TXNDC5 Gene

Paralogs for BLOC1S5-TXNDC5 Gene

(1) SIMAP similar genes for BLOC1S5-TXNDC5 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with BLOC1S5-TXNDC5: view

Variants for BLOC1S5-TXNDC5 Gene

Sequence variations from dbSNP and Humsavar for BLOC1S5-TXNDC5 Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type
rs910552 -- 8,001,045(+) TATGG(A/C)CTTCA intron-variant
rs910553 -- 8,001,104(+) TGGAT(A/G)GATTA intron-variant
rs959557 -- 8,010,935(+) GAGAT(A/G)GGAAA intron-variant
rs965543 -- 7,963,884(+) ccccc(A/C)aaaag intron-variant
rs967999 -- 7,971,185(+) GATGA(A/T)GACAG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for BLOC1S5-TXNDC5 Gene

Variant ID Type Subtype PubMed ID
esv2658338 CNV deletion 23128226
esv2665768 CNV deletion 23128226
esv2731544 CNV deletion 23290073
esv3306258 CNV mobile element insertion 20981092
esv3356211 CNV insertion 20981092
esv3570751 CNV loss 25503493
esv3570752 CNV loss 25503493
esv3570754 CNV loss 25503493
esv3576096 CNV gain 25503493
esv3608020 CNV loss 21293372
esv3608021 CNV loss 21293372
esv3608022 CNV loss 21293372
esv3890787 CNV loss 25118596
nsv1074375 CNV deletion 25765185
nsv1109758 CNV deletion 24896259
nsv1124025 CNV deletion 24896259
nsv1133014 OTHER inversion 24896259
nsv1140603 CNV deletion 24896259
nsv1140604 CNV deletion 24896259
nsv1145091 CNV deletion 24896259
nsv1151332 OTHER inversion 26484159
nsv462625 CNV loss 19166990
nsv462626 CNV loss 19166990
nsv600924 CNV gain 21841781
nsv600925 CNV loss 21841781
nsv600926 CNV loss 21841781
nsv600927 CNV gain 21841781
nsv819508 CNV loss 19587683
nsv830582 CNV loss 17160897
nsv965680 CNV duplication 23825009

Relevant External Links for BLOC1S5-TXNDC5 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
BLOC1S5-TXNDC5

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for BLOC1S5-TXNDC5 Gene

Disorders for BLOC1S5-TXNDC5 Gene

Relevant External Links for BLOC1S5-TXNDC5

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
BLOC1S5-TXNDC5

No disorders were found for BLOC1S5-TXNDC5 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for BLOC1S5-TXNDC5 Gene

Publications for BLOC1S5-TXNDC5 Gene

  1. Genetics of coronary artery calcification among African Americans, a meta-analysis. (PMID: 23870195) Wojczynski M.K. … Reilly M.P. (BMC Med. Genet. 2013) 3 65
  2. Expression of conjoined genes: another mechanism for gene regulation in eukaryotes. (PMID: 20967262) Prakash T. … Taylor T.D. (PLoS ONE 2010) 3 65
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3 65
  4. The sequence of the human genome. (PMID: 11181995) Venter J.C. … Zhu X. (Science 2001) 3 65

Products for BLOC1S5-TXNDC5 Gene

Sources for BLOC1S5-TXNDC5 Gene

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