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BLOC1S4 Gene

protein-coding   GIFtS: 46
GCID: GC04P006718

Biogenesis Of Lysosomal Organelles Complex-1, Subunit 4,...

(Previous name: cappuccino homolog (mouse))
(Previous symbol: CNO)
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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Biogenesis Of Lysosomal Organelles Complex-1, Subunit 4, Cappuccino1 2     Cappuccino Homolog (Mouse)1
CNO1 2 3 5     BCAS4L2
Protein Cappuccino Homolog2 3     Biogenesis Of Lysosome-Related Organelles Complex 1 Subunit 42
BLOC-1 Subunit 42 3     Cappuccino Homolog2
BLOS42 5     

External Ids:    HGNC: 242061   Entrez Gene: 553302   Ensembl: ENSG000001862227   OMIM: 6056955   UniProtKB: Q9NUP13   

Export aliases for BLOC1S4 gene to outside databases


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for BLOC1S4 Gene:
This intronless gene encodes a protein that may play a role in organelle biogenesis associated with melanosomes,
platelet dense granules, and lysosomes. A similar protein in mouse is a component of a protein complex termed
biogenesis of lysosome-related organelles complex 1 (BLOC-1), and is a model for Hermansky-Pudlak syndrome. The
encoded protein may play a role in intracellular vesicular trafficking. (provided by RefSeq, Jul 2008)

GeneCards Summary for BLOC1S4 Gene:
BLOC1S4 (biogenesis of lysosomal organelles complex-1, subunit 4, cappuccino) is a protein-coding gene. An important paralog of this gene is BCAS4.

UniProtKB/Swiss-Prot: BL1S4_HUMAN, Q9NUP1
Function: Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related
organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1
complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into
neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be
involved in neurite extension. Plays a role in intracellular vesicle trafficking

Gene Wiki entry for BLOC1S4 (CNO) Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000004.11  NC_018915.2  NT_006051.19  
Regulatory elements:
   Search for regulatory transcription factor binding sites for BLOC1S4
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidBLOC1S4 promoter sequence
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Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat BLOC1S4


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 4p16.1   Ensembl cytogenetic band:  4p16.1   HGNC cytogenetic band: 4p16.1

BLOC1S4 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
BLOC1S4 gene location

GeneLoc information about chromosome 4         GeneLoc Exon Structure

GeneLoc location for GC04P006718:  view genomic region     (about GC identifiers)

Start:
6,717,842 bp from pter      End:
6,719,387 bp from pter
Size:
1,546 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: BL1S4_HUMAN, Q9NUP1 (See protein sequence)
Recommended Name: Biogenesis of lysosome-related organelles complex 1 subunit 4  
Size: 217 amino acids; 23351 Da
Subunit: Interacts with BLOC1S5 and BLOC1S6 (By similarity). Component of the biogenesis of lysosome-related
organelles complex 1 (BLOC-1) composed of BLOC1S1, BLOC1S2, BLOC1S3, BLOC1S4, BLOC1S5, BLOC1S6, DTNBP1/BLOC1S7
and SNAPIN/BLOC1S8. Octamer composed of one copy each BLOC1S1, BLOC1S2, BLOC1S3, BLOC1S4, BLOC1S5, BLOC1S6,
DTNBP1/BLOC1S7 and SNAPIN/BLOC1S8. The BLOC-1 complex associates with the AP-3 protein complex and membrane
protein cargos
Secondary accessions: Q6NVY6 Q96G84

Explore the universe of human proteins at neXtProt for BLOC1S4: NX_Q9NUP1

Explore proteomics data for BLOC1S4 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See BLOC1S4 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_060836.1  
    ENSEMBL proteins: 
     ENSP00000318128  
    Reactome Protein details: Q9NUP1

    BLOC1S4 Human Recombinant Protein Products:

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    BLOC1S: Biogenesis of lysosomal organelles complex-1 subunits

    1 InterPro protein domain:
     IPR024857 Cappuccino

    Graphical View of Domain Structure for InterPro Entry Q9NUP1

    ProtoNet protein and cluster: Q9NUP1

    UniProtKB/Swiss-Prot: BL1S4_HUMAN, Q9NUP1
    Similarity: Belongs to the BLOC1S4 family


    Find genes that share domains with BLOC1S4           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: BL1S4_HUMAN, Q9NUP1
    Function: Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related
    organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1
    complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into
    neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be
    involved in neurite extension. Plays a role in intracellular vesicle trafficking

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI15102850
         
    Find genes that share ontologies with BLOC1S4           About GenesLikeMe


    Phenotypes:
         3 GenomeRNAi human phenotypes for BLOC1S4:
     Increased G2M DNA content  Increased HPV18 LCR reporter a  Increased gamma-H2AX phosphory 

         10 MGI mutant phenotypes (inferred from 1 allele(MGI details for Bloc1s4):
     behavior/neurological  cellular  hematopoietic system  homeostasis/metabolism  integument 
     liver/biliary system  pigmentation  renal/urinary system  respiratory system  vision/eye 

    Find genes that share phenotypes with BLOC1S4           About GenesLikeMe

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for BLOC1S4
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    miRNA
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    miRTarBase miRNAs that target BLOC1S4:
    hsa-mir-30c-5p (MIRT048016)

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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    BL1S4_HUMAN, Q9NUP1: Cytoplasm (By similarity)

    Gene Ontology (GO): 3 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm ISS--
    GO:0005829cytosol TAS--
    GO:0031083BLOC-1 complex IDA--

    Find genes that share ontologies with BLOC1S4           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for BLOC1S4 About    
    See pathways by source

    SuperPathContained pathways About
    1Clathrin derived vesicle budding
    Clathrin derived vesicle budding0.89
    trans-Golgi Network Vesicle Budding0.89
    Golgi Associated Vesicle Biogenesis0.89
    Membrane Trafficking0.32


    Find genes that share SuperPaths with BLOC1S4           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 Reactome Pathway for BLOC1S4
        Golgi Associated Vesicle Biogenesis


        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for BLOC1S4
    Interactions:

        Search GeneGlobe Interaction Network for BLOC1S4

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for BLOC1S4 (Q9NUP11, 2, 3 ENSP000003181284) via UniProtKB, MINT, STRING, and/or I2D (see all 27)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    BLOC1S6Q9UL451, 3, ENSP000002205314EBI-465852,EBI-465781 I2D: score=5 STRING: ENSP00000220531
    AIMP2Q131552, 3, ENSP000002230294MINT-8258828 I2D: score=2 STRING: ENSP00000223029
    EPB42P164523, ENSP000003002154I2D: score=1 STRING: ENSP00000300215
    BLOC1S5Q8TDH93, ENSP000003805984I2D: score=3 STRING: ENSP00000380598
    SNAPINO952953, ENSP000003576744I2D: score=4 STRING: ENSP00000357674
    About this table

    Gene Ontology (GO): Selected biological process terms (see all 8):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006892post-Golgi vesicle-mediated transport TAS--
    GO:0008089anterograde axon cargo transport ISS--
    GO:0031175neuron projection development ISS--
    GO:0032438melanosome organization NAS--
    GO:0048490anterograde synaptic vesicle transport ISS--

    Find genes that share ontologies with BLOC1S4           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for BLOC1S4 (BL1S4)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for BLOC1S4 gene: 
    NM_018366.2  

    Unigene Cluster for BLOC1S4:

    Biogenesis of lysosomal organelles complex-1, subunit 4, cappuccino
    Hs.7570  [show with all ESTs]
    Unigene Representative Sequence: NM_018366
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000320776(uc003gjp.1)
    miRNA
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      QuantiTect SYBR Green Assays in human, mouse, rat BLOC1S4
      QuantiFast Probe-based Assays in human, mouse, rat BLOC1S4

    Additional mRNA sequence: 

    AF085849.1 AK002092.1 BC001818.2 BC009890.2 BC067815.1 

    5 DOTS entries:

    DT.111572  DT.100663270  DT.100663286  DT.40236235  DT.100663285 

    Selected AceView cDNA sequences (see all 104):

    BQ061216 BC001818 BM916494 BQ020453 BG054967 BG479247 C01626 BM844808 
    CR598245 CR613059 BU849885 BM760698 BC009890 AF085849 CR599774 CR603319 
    BF197408 AW294343 BM842490 AI679712 NM_018366 BX104396 CR625701 BM843183 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    BLOC1S4 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    BLOC1S4 Expression
    About this image

    BLOC1S4 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    BLOC1S4 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.7570
        Custom PCR Arrays for BLOC1S4
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    In Situ
    Assay Products:
     

     
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for BLOC1S4 gene from Selected species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Bloc1s41 , 5 cappuccino5
    biogenesis of lysosomal organelles complex-1, subunit more1
    82.75(n)1
    82.41(a)1
      5 (19.24 cM)5
    1171971  NM_133724.31  NP_598485.11 
     367473745 
    chicken
    (Gallus gallus)
    Aves CNO1 cappuccino homolog (mouse) 65.05(n)
    59.46(a)
      421000  XM_419086.4  XP_419086.4 
    lizard
    (Anolis carolinensis)
    Reptilia BLOC1S46
    biogenesis of lysosomal organelles complex-1, subu...
    67(a)
    1 ↔ 1
    4(53252733-53255248)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia bloc1s41 biogenesis of lysosomal organelles complex-1, subunit more 54.58(n)
    49.45(a)
      733711  NM_001044488.2  NP_001037953.1 
    zebrafish
    (Danio rerio)
    Actinopterygii bloc1s41 biogenesis of lysosomal organelles complex-1, subunit more 56.47(n)
    53.01(a)
      445081  NM_001003475.1  NP_001003475.1 


    ENSEMBL Gene Tree for BLOC1S4 (if available)
    TreeFam Gene Tree for BLOC1S4 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for BLOC1S4 gene
    BCAS42  
    1 SIMAP similar gene for BLOC1S4 using alignment to 1 protein entry:     BL1S4_HUMAN:
    BCAS4

    Find genes that share paralogs with BLOC1S4           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for BLOC1S4 (see all 88)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 4 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1820085011,2
    --6651552(+) CCTCTC/TGAAAT 1 -- ds50010--------
    rs1816161591,2
    --6715880(+) GTGTAC/TGACCA 1 -- us2k10--------
    rs357900541,2
    C--6715897(+) GCTAA-/TTTTTG 1 -- us2k11Minor allele frequency- T:0.00NA 2
    rs1872513991,2
    --6715938(+) CCAGGA/CTGGTC 1 -- us2k10--------
    rs1907678341,2
    --6715940(+) AGGCTG/TGTCTT 1 -- us2k10--------
    rs117315911,2
    H--6716128(+) ttgccC/Ttaagc 1 -- us2k10--------
    rs1413946811,2
    --6716305(+) TCACTA/GAGTCC 1 -- us2k10--------
    rs592907361,2
    C,F--6716428(+) ATTCTT/GCATGC 1 -- us2k12Minor allele frequency- G:0.13WA 120
    rs1818104361,2
    --6716568(+) TCAATA/CAGATC 1 -- us2k10--------
    rs1508262461,2
    --6716834(+) GCCATC/GCAGTC 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for BLOC1S4 (6717842 - 6719387 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for BLOC1S4: --
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing BLOC1S4
    DNA2.0 Custom Variant and Variant Library Synthesis for BLOC1S4

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 605695    OMIM disorders: --


    Find genes that share disorders with BLOC1S4           About GenesLikeMe


    Export disorders for BLOC1S4 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for BLOC1S4 gene, integrated from 10 sources (see all 17):
    (articles sorted by number of sources associating them with BLOC1S4)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    3. Cappuccino, a mouse model of Hermansky-Pudlak syndrome, encodes a novel protein that is part of the pallidin-muted complex (BLOC-1). (PubMed id 12576321)1, 3 Ciciotte S.L....Peters L.L. (Blood 2003)
    4. Defects in the cappuccino (cno) gene on mouse chromosome 5 and human 4p cause Hermansky-Pudlak syndrome by an AP-3-independent mechanism. (PubMed id 11110696)1, 3 Gwynn B....Peters L.L. (Blood 2000)
    5. Pathway Analysis of ChIP-Seq-Based NRF1 Target Genes Suggests a Logical Hypothesis of their Involvement in the Pathogenesis of Neurodegenerative Diseases. (PubMed id 24250222)1 Satoh J....Yamamoto Y. (Gene Regul Syst Bio 2013)
    6. Targeting protein-trafficking pathways alters melanoma treatment sensitivity. (PubMed id 22203954)1 Huang Z.M....Wei M.L. (Proc. Natl. Acad. Sci. U.S.A. 2012)
    7. Assembly and architecture of biogenesis of lysosome-related organelles complex-1 (BLOC-1). (PubMed id 22203680)2 Lee H.H.... Hurley J.H. (J. Biol. Chem. 2012)
    8. A directed protein interaction network for investigating intracellular signal transduction. (PubMed id 21900206)1 Vinayagam A....Wanker E.E. (Sci Signal 2011)
    9. BLOC-1 is required for cargo-specific sorting from vacuolar early endosomes toward lysosome-related organelles. (PubMed id 17182842)2 Setty S.R.... Marks M.S. (Mol. Biol. Cell 2007)
    10. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PubMed id 15815621)2 Hillier L.W.... Wilson R.K. (Nature 2005)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    Aliases
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      Query String
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    OMIM
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 55330 HGNC: 24206 AceView: CNO Ensembl:ENSG00000186222 euGenes: HUgn55330
    ECgene: BLOC1S4 H-InvDB: BLOC1S4

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for BLOC1S4 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for BLOC1S4 gene:
    Search GeneIP for patents involving BLOC1S4

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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