BLMH Gene
protein-coding GIFtS: 66
GCID: GC17M028575
|
|
bleomycin hydrolase
| |
Aliases for BLMH gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb) About This Section
|
| Aliases |
|---|
| Bleomycin Hydrolase1 2 | | BH1 2 3 | | BMH2 3 5 | | BLM Hydrolase2 3 | | EC 3.4.22.403 8 |
Export aliases for BLMH gene to outside databasesPrevious GC identifers: GC17M028328 GC17M030481 GC17M028720 GC17M025599 GC17M024785 |
Summaries for BLMH gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| Entrez Gene summary for BLMH: Bleomycin hydrolase (BMH) is a cytoplasmic cysteine peptidase that is highly conserved through evolution; however, theonly known activity of the enzyme is metabolic inactivation of the glycopeptide bleomycin (BLM), an essentialcomponent of combination chemotherapy regimens for cancer. The protein contains the signature active site residues ofthe cysteine protease papain superfamily. (provided by RefSeq, Jul 2008) UniProtKB/Swiss-Prot: BLMH_HUMAN, Q13867Function: The normal physiological role of BLM hydrolase is unknown, but it catalyzes the inactivation of the antitumordrug BLM (a glycopeptide) by hydrolyzing the carboxamide bond of its B-aminoalaninamide moiety thus protecting normaland malignant cells from BLM toxicity (By similarity) Gene Wiki entry for BLMH
|
Genomic Views for BLMH gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics) About This Section
| RefSeq DNA sequence:- NC_000017.10 NC_018928.1 NT_010799.15
Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the BLMH gene promoter: HFH-3 GR Pbx1a GR-beta Tal-1beta E47 AREB6 c-Myb GR-alpha Other transcription factors
Search SABiosciences Chromatin IP Primers for BLMH
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat BLMH |
Genomic Location: Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 17q11.2 Ensembl cytogenetic band: 17q11.2 HGNC cytogenetic band: 17q11.2BLMH Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different)

GeneLoc information about chromosome 17 GeneLoc Exon Structure GeneLoc location for GC17M028575: view genomic region
(about GC identifiers)
Start:
|
28,575,218 bp from pter |
End:
|
28,619,074 bp from pter |
Size:
|
43,857 bases |
Orientation:
|
minus strand |
|
Proteins for BLMH gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
| UniProtKB/Swiss-Prot: BLMH_HUMAN, Q13867 (See
protein sequence)Recommended Name: Bleomycin hydrolase Size: 455 amino acids; 52562 Da
Subunit: Homohexamer
Subcellular location: Cytoplasm
2 PDB 3D structures from and Proteopedia for BLMH:1CB5 (3D)
  2CB5 (3D)
 
Secondary accessions: B2R796 Q53F86 Q9UER9Explore the universe of human proteins at neXtProt for BLMH: NX_Q13867
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q13867 4/17 DME Specific Peptides for BLMH (Q13867) (see all 17)
BLMH Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_000377.1 ENSEMBL proteins: ENSP00000261714 ENSP00000462353 ENSP00000468681 ENSP00000462442 ENSP00000468486 ENSP00000466527 ENSP00000466948 ENSP00000378296 Reactome Protein details: Q13867 Human Recombinant Protein Products:
Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view): About this table
BLMH for ontologies About GeneDecksing
BLMH Antibody Products: Assay Products for BLMH: |
Protein
Domains / Families for BLMH gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
BLMH for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q13867ProtoNet protein and cluster: Q13867 1 Blocks protein family: IPB004134 Peptidase C1-like family
UniProtKB/Swiss-Prot: BLMH_HUMAN, Q13867Similarity: Belongs to the peptidase C1 family |
Function for BLMH gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
| Function Summary: UniProtKB/Swiss-Prot: BLMH_HUMAN, Q13867Function: The normal physiological role of BLM hydrolase is unknown, but it catalyzes the inactivation of the antitumordrug BLM (a glycopeptide) by hydrolyzing the carboxamide bond of its B-aminoalaninamide moiety thus protecting normaland malignant cells from BLM toxicity (By similarity)Catalytic activity: Inactivates bleomycin B2 (a cytotoxic glycometallopeptide) by hydrolysis of a carboxyamide bond ofbeta-aminoalanine, but also shows general aminopeptidase activity. The specificity varies somewhat with source, butamino acid arylamides of Met, Leu and Ala are preferred Genatlas biochemistry entry for BLMH:bleomycin hydrolase,neutral cysteine protease,papain superfamily,widely expressed,maybe involved in bleomycin inducedpulmonary fibrosis Enzyme Number (IUBMB): EC 3.4.22.401 2
Clone Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for BLMH (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for BLMH OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: BLMH (NM_000386) | |  | Sino Biological Human cDNA Clone for BLMH | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for BLMH | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat BLMH  |
In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for BLMH |
Gene Ontology (GO): 5/6 molecular function terms (GO ID links to tree view) (see all 6): About this table
BLMH for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for BLMH: Animal Models: Mouse knock-out Blmhtm1Geh for BLMH 8 MGI mutant phenotypes (inferred from 1 allele ) (MGI details for Blmh):
BLMH for phenotypes About GeneDecksing
|
Pathways & Interactions for BLMH gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
| Unified GeneCards pathways  About this table  See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Immune System | | | 2 | Antigen processing: Ubiquitination & Proteasome degradation | | | 3 | Trimming of N-ter extended precursor fragments by cytosolic aminopeptidases | |
Pathway sources See GeneCards unified pathways Show all pathways
5
Reactome Pathways for BLMH
BLMH for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for BLMH
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
 5/83 Interacting proteins for BLMH (Q138671, 2, 3 ENSP000002617144) via UniProtKB, MINT, STRING, and/or I2D (see all 83)About this table
Gene Ontology (GO): 5 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0000209 | protein polyubiquitination |
TAS | -- | | GO:0002474 | antigen processing and presentation of peptide antigen via MHC class I |
TAS | -- | | GO:0006508 | proteolysis |
IEA | -- | | GO:0009636 | response to toxin |
IEA | -- | | GO:0042493 | response to drug |
IEA | -- |
BLMH for ontologies About GeneDecksing
|
Drugs & Compounds for BLMH gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
BLMH for compounds About GeneDecksing
Browse Tocris compounds for BLMH 5 Novoseek chemical compound relationships for BLMH gene About this table
Search CenterWatch for drugs/clinical trials and news about BLMH 
|
Transcripts for BLMH gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
) About This Section
| REFSEQ mRNAs for BLMH gene: NM_000386.3 Unigene Cluster for BLMH: Bleomycin hydrolase Hs.371914 [show with all ESTs]Unigene Representative Sequence: NM_00038614 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000261714(uc002hez.2 uc010wbn.2) ENST00000578795 ENST00000578090 ENST00000577623 ENST00000579957 ENST00000581037 ENST00000577306 ENST00000584603 ENST00000582669 ENST00000579325 ENST00000580709 ENST00000577290 ENST00000582749 ENST00000394819
Clone Products: |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for BLMH (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for BLMH OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: BLMH (NM_000386) | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for BLMH | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat BLMH  |
Additional cDNA sequence: AF091082.1 AK057600.1 AK223403.1 AK301948.1 AK312896.1 BC003616.2 BT007018.1 X92106.1 17 DOTS entries: DT.101983117 DT.315911 DT.95124813 DT.100807028 DT.95124820 DT.100810339 DT.100810343 DT.100810344 DT.417729 DT.120916053 DT.92458086 DT.95124811 DT.100693584 DT.92458092 DT.95124772 DT.97859808 DT.75186169 24/342 AceView cDNA sequences (see all 342): BQ072971 AA927540 BM676957 BQ424536 AA994117 AA705502 BU167345 AI318426 AU130273 AA774218 AA701306 BQ687565 BE782971 CA426434 BE780996 W74447 AA417881 AU121157 BQ690347 BE396899 AU123836 AU279450 CB988732 AA903743 GeneLoc Exon Structure
5/15 Alternative Splicing Database (ASD) splice patterns (SP) for BLMH (see all 15) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2a | · | 2b | · | 2c | ^ | 3 | ^ | 4a | · | 4b | · | 4c | ^ | 5a | · | 5b | ^ | 6a | · | 6b | ^ | 7a | · | 7b | · | 7c | · | 7d | ^ | 8a | · | 8b | ^ | 9 | ^ | 10a | · | 10b | ^ | 11a | · | 11b | ^ | 12a | · | |
| SP1: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | - |   | - |   | |   | |   | |   | - |   | - |   | - |   | |   | |   | |   | |   | |
| SP2: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | - |   | - |   | |   | |   | |   | - |   | - |   | - |   | |   | |   | - |   | |   | |
| SP3: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | - |   | - |   | - |   | |   | |   | - |   | |   | |
| SP4: | |   | |   | |   | |   | - |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | - |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP5: | |   | |   | |   | |   | - |   | - |   | |   | - |   | - |   | - |   | - |   | - |   | - |   | - |   | - |   | - |   | - |   | - |   | - |   | - |   | - |   | - |   | - |   | - |   | - |   | - |   |
| ExUns: | 12b | ^ | 13 | ^ | 14a | · | 14b | |
| SP1: | |   | |   | |   | |   | |
| SP2: | |   | |   | |   | |   | |
| SP3: | |   | |   | |   | |   | |
| SP4: | |   | |   | |   | |   | |
| SP5: | |   | |   | |   | |   |
ECgene alternative splicing isoforms for BLMH
|
Expression for BLMH gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| BLMH expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this imageBioGPS CGAP TAG: GTCTCAGTCA
About this image See BLMH Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for BLMH
SOURCE GeneReport for Unigene cluster: Hs.371914 SABiosciences Expression via Pathway-Focused PCR Array including BLMH:
Primer Products: |  | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for BLMH Browse OriGene validated miRNA SYBR primer pairs
| |  | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat BLMH | |  | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat BLMH | |  | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat BLMH | In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for BLMH |
Orthologs for BLMH gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals and fungi.
Orthologs for BLMH gene from 7/25 species (see all 25) About this table
| Organism |
Taxonomic classification |
Gene |
Description |
Human Similarity |
Orthology Type |
Details |
mouse (Mus musculus) |
Mammalia |
Blmh1 , 5 |
bleomycin hydrolase1, 5 |
91.14(n)1 93.19(a)1 |
  |
11 (46.16 cM)5 1041841 NM_178645.41 NP_848760.11 769248095 |
chicken (Gallus gallus) |
Aves |
BLMH1 |
bleomycin hydrolase |
74.51(n) 75.38(a) |
  |
395996 NM_205104.1 NP_990435.1 |
lizard (Anolis carolinensis) |
Reptilia |
BLMH6 |
-- |
73(a) |
1 ↔ 1 |
GL343462.1(509660-521692) |
African clawed frog (Xenopus laevis) |
Amphibia |
Xl.98462 |
Xenopus laevis transcribed sequence with moderate similarity more |
77.18(n) |
  |
BJ033232.1 |
zebrafish (Danio rerio) |
Actinopterygii |
wufb13c012 |
wufb13c01 |
75.48(n) |
  |
336541 BC055572.1 |
fruit fly (Drosophila melanogaster) |
Insecta |
CG14401 , 3 |
cysteine-type endopeptidase3 CG14401 |
54(a) (best of 2)3 59.22(n)1 57.6(a)1 |
  |
7E93 317761 NM_001103437.11 NP_001096907.11 |
baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes |
LAP3(YNL239W)4 LAP31 |
Cysteine aminopeptidase with homocysteine-thiolactonase more4 Lap3p1 |
48.38(n)1 40.86(a)1 |
  |
14(200569-201933)4 8554821, 4 NP_014160.21, 4 |
ENSEMBL Gene Tree for BLMH (if available) TreeFam Gene Tree for BLMH (if available)  |
Paralogs for BLMH gene(Paralogs according to
1HomoloGene, 2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68) About This Section
| -- |
Genomic Variants for BLMH gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical significance | Chr 17 pos | Sequence | # | AA Chg | Type | More | # | Allele freq | Pop | Total sample | More |
|---|
HapMap Linkage Disequilibrium report for BLMH (28575218 - 28619074 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV): 1 variation for BLMH 1 CNV: 102436 Human Gene Mutation Database (HGMD): BLMH
 | SABiosciences Cancer Mutation PCR Assays |
|  | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing BLMH |
|
Disorders
/ Diseases for BLMH gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
BLMH for disorders About GeneDecksing
OMIM gene information: 602403 OMIM disorders: 104300 20/21 diseases for BLMH (see all 21): About MalaCardspityriasis rubra pilaris hydrops fetalis mutagen sensitivity testicular germ cell cancer iron overload alpha thalassemia intellectual disability autistic disorder alzheimer's disease atopic dermatitis neurodegenerative disease germ cell cancer thalassemia pulmonary fibrosis dermatitis dementia homocysteine fibrosis hepatocellular carcinoma pneumonia
1 disease from the University of Copenhagen DISEASES database for BLMH:Alzheimer's disease 7 Novoseek disease relationships for BLMH gene About this table
Genetic Association Database (GAD): BLMH Human Genome Epidemiology (HuGE) Navigator: BLMH (9 documents) Export disorders for BLMH gene to outside databases
|
Publications for BLMH gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for BLMH gene, integrated from 9 sources (see all 82): (articles sorted by number of sources associating them with BLMH) | |  | Utopia: connect your pdf to the dynamic world of online information |
- Cloning and expression analysis of human bleomycin hydrolase, a cysteine proteinase involved in chemotherapy resistance. (PubMed id 8620487)1, 2, 9 Ferrando A.A.... Lopez-Otin C. (1996)
- Genetic variation in the bleomycin hydrolase gene and bleomycin-induced pulmonary toxicity in germ cell cancer patients. (PubMed id 15900213)1, 4, 9 Nuver J....Gietema J.A. (2005)
- Crystal structure of human bleomycin hydrolase, a self- compartmentalizing cysteine protease. (PubMed id 10404591)1, 2, 9 O'Farrell P.A.... Joshua-Tor L. (1999)
- Human bleomycin hydrolase: molecular cloning, sequencing, functional expression, and enzymatic characterization. (PubMed id 8639621)1, 2, 9 Broemme D.... Payan D.G. (1996)
- Gene characterization, promoter analysis, and chromosomal localization of human bleomycin hydrolase. (PubMed id 9407121)1, 3, 9 Ferrando A.A....Lopez-Otin C. (1997)
- Genomic structure and genetic mapping of the human neutral cysteine protease bleomycin hydrolase. (PubMed id 9331073)1, 3, 9 Montoya S.E....Lazo J.S. (1997)
- Lack of replication of association findings in complex disease: an analysis of 15 polymorphisms in prior candidate genes for sporadic Alzheimer's disease. (PubMed id 11436125)1, 4, 9 Prince J.A....Brookes A.J. (2001)
- Genetic risk factors of sporadic Alzheimer's disease among Chinese in Taiwan. (PubMed id 11099722)1, 4, 9 Hu C.J....Chang J.G. (2000)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Genetic polymorphisms of DNA repair and xenobiotic-metabolizing enzymes: role in mutagen sensitivity. (PubMed id 12082022)1, 4 Tuimala J....Norppa H. (2002)
|
External Searches for BLMH gene
(in PubMed,
OMIM, and NCBI Bookshelf) About This Section
|
|
Genome Databases showing BLMH gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing BLMH gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing BLMH gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
|
|
About This Section
| Patent Information for BLMH gene: Search GeneIP for patents involving BLMH
GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products for BLMH gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences), In Situ Hybridization Assays from Advanced Cell Diagnostics About This Section
|
 | |
 | |
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| | | | Browse OriGene Antibodies | | OriGene shRNA RFP for BLMH | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for BLMH | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for BLMH | | OriGene Protein Over-expression Lysate for BLMH | | Browse OriGene Fluorogenic Cell Assay Kits | | OriGene siRNA for BLMH | | OriGene 3'-UTR Clone for BLMH | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for BLMH | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for BLMH | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | OriGene Custom Antibody Services for BLMH | | OriGene Custom Protein Services for BLMH | | OriGene Custom Immunoassay Development | | |
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| | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat BLMH | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing BLMH | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat BLMH | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat BLMH | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat BLMH | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat BLMH |
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| | | Search Tocris compounds for BLMH |
| |  |  |  |  | | | | | Recombinant Protein for BLMH |
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 | | BLMH Proteins, Antibodies, CLIAs, and ELISAs |
| | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for BLMH |
|  |  |  | | | Search ThermoFisher Antibodies for BLMH |
| | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat BLMH |
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