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BLCAP Gene

protein-coding   GIFtS: 50
GCID: GC20M036130

Bladder Cancer Associated Protein

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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This gene clusters with an RNA gene
Subcategory (RNA class): antisense

Quality score for the ORGUL clustered with this gene is 3

Aliases
Bladder Cancer Associated Protein1 2
BC102 3 5
Bladder Cancer 10 KDa Protein2 3
Bladder Cancer Related Protein (10kD)2
Bladder Cancer-Associated Protein2
Bc103

External Ids:    HGNC: 10551   Entrez Gene: 109042   Ensembl: ENSG000001666197   OMIM: 6131105   UniProtKB: P629523   
ORGUL members:         

Export aliases for BLCAP gene to outside databases

Previous GC identifers: GC20M035874 GC20M036784 GC20M036831 GC20M035579 GC20M032881


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for BLCAP Gene:
This gene encodes a tumor suppressor protein that reduces cell growth by stimulating apoptosis. The first intron
of this gene contains the neuronatin gene, which is imprinted and only expressed from the paternal allele. This
gene is imprinted in brain where it is differentially expressed from different promoters. Transcription from the
upstream promoter occurs preferentially on the maternal allele, and transcripts are preferentially expressed from
the downstream promoter on the paternal allele. Alternative promoters and alternative splicing result in multiple
transcript variants that encode the same protein.(provided by RefSeq, Nov 2009)

GeneCards Summary for BLCAP Gene:
BLCAP (bladder cancer associated protein) is a protein-coding gene. Diseases associated with BLCAP include bladder transitional cell carcinoma, and transitional cell carcinoma.

UniProtKB/Swiss-Prot: BLCAP_HUMAN, P62952
Function: May regulate cell proliferation and coordinate apoptosis and cell cycle progression via a novel
mechanism independent of both p53/TP53 and NF-kappa-B

Gene Wiki entry for BLCAP Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000020.11  NC_018931.2  NT_011362.11  
Regulatory elements:
   Regulatory transcription factor binding sites in the BLCAP gene promoter:
         NF-kappaB   HNF-4alpha1   C/EBPalpha   AREB6   PPAR-gamma1   PPAR-gamma2   NF-kappaB1   c-Myc   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidBLCAP promoter sequence
   Search Chromatin IP Primers for BLCAP

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat BLCAP


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 20q11.23   Ensembl cytogenetic band:  20q11.23   HGNC cytogenetic band: 20q11.23

BLCAP Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
BLCAP gene location

GeneLoc information about chromosome 20         GeneLoc Exon Structure

GeneLoc location for GC20M036130:  view genomic region     (about GC identifiers)

Start:
36,120,874 bp from pter      End:
36,156,333 bp from pter
Size:
35,460 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: BLCAP_HUMAN, P62952 (See protein sequence)
Recommended Name: Bladder cancer-associated protein  
Size: 87 amino acids; 9876 Da
Rna editing: Modified_positions=2, 5, 15; Note=Partially edited. Decreased editing levels seen in astrocytomas,
bladder cancer and colorectal cancer as compared to the related normal tissues
Secondary accessions: A2A2K7 O60629 Q9D3B5

Explore the universe of human proteins at neXtProt for BLCAP: NX_P62952

Explore proteomics data for BLCAP at MOPED


See BLCAP Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

REFSEQ proteins (5 alternative transcripts): 
NP_001161292.1  NP_001161293.1  NP_001161294.1  NP_001161295.1  NP_006689.1  

ENSEMBL proteins: 
 ENSP00000380326   ENSP00000362637   ENSP00000380324   ENSP00000380323   ENSP00000380320  
 ENSP00000414973   ENSP00000405953   ENSP00000391768   ENSP00000389735   ENSP00000397172  

BLCAP Human Recombinant Protein Products:

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Novus Biologicals BLCAP Protein
Novus Biologicals BLCAP Lysate
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Cloud-Clone Corp. Proteins for BLCAP

BLCAP Antibody Products:

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Novus Biologicals BLCAP Antibody
Abcam antibodies for BLCAP
Cloud-Clone Corp. Antibodies for BLCAP
Search ThermoFisher Antibodies for BLCAP
LSBio Antibodies in human, mouse, rat for BLCAP

BLCAP Assay Products:

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Cloud-Clone Corp. ELISAs for BLCAP
Cloud-Clone Corp. CLIAs for BLCAP


(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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2 InterPro protein domains:
 IPR018015 BC10-like
 IPR009598 BC10

Graphical View of Domain Structure for InterPro Entry P62952

ProtoNet protein and cluster: P62952

1 Blocks protein domain: IPB009598 Bladder cancer-related BC10

UniProtKB/Swiss-Prot: BLCAP_HUMAN, P62952
Similarity: Belongs to the BLCAP family


BLCAP for domains           About GeneDecksing


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Molecular Function:

     UniProtKB/Swiss-Prot Summary: BLCAP_HUMAN, P62952
Function: May regulate cell proliferation and coordinate apoptosis and cell cycle progression via a novel
mechanism independent of both p53/TP53 and NF-kappa-B

     Gene Ontology (GO): 1 molecular function term:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005515protein binding IPI--
     
BLCAP for ontologies           About GeneDecksing


Animal Models:
   inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for BLCAP
   inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for BLCAP

   genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for BLCAP
   genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for BLCAP

miRNA
Products:
    
miRTarBase miRNAs that target BLCAP:
hsa-mir-1 (MIRT002760), hsa-mir-19b-3p (MIRT031277), hsa-mir-130b-3p (MIRT020294), hsa-mir-218-5p (MIRT024216), hsa-mir-138-5p (MIRT006865), hsa-mir-1301-3p (MIRT035995)

Block miRNA regulation of human, mouse, rat BLCAP using miScript Target Protectors
Selected qRT-PCR Assays for microRNAs that regulate BLCAP (see all 81):
hsa-miR-607 hsa-miR-520e hsa-miR-519a hsa-miR-4274 hsa-miR-200b hsa-miR-130b hsa-miR-520b hsa-miR-130a*
SwitchGear 3'UTR luciferase reporter plasmidBLCAP 3' UTR sequence
Inhib. RNA
Products:
    
OriGene RNAi products in human, mouse, rat for BLCAP
Predesigned siRNA for gene silencing in human, mouse, rat BLCAP

Gene Editing
Products:
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Clone
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OriGene clones in human, mouse for BLCAP (see all 24)
OriGene ORF clones in mouse, rat for BLCAP
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript: all cDNA clones in your preferred vector (see all 5): BLCAP (NM_006698)
Sino Biological Human cDNA Clone for BLCAP
DNA2.0 Custom Codon Optimized Gene Synthesis Service for BLCAP
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat BLCAP

Cell Line
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In Situ Assay
Products:
   

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for BLCAP


(According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Subcellular locations from UniProtKB/Swiss-Prot
BLCAP_HUMAN, P62952: Membrane; Multi-pass membrane protein (Potential)
Subcellular locations from COMPARTMENTS: 

CompartmentConfidence
extracellular3
cytosol1
mitochondrion1

Gene Ontology (GO): 1 cellular component term:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0016021integral component of membrane IEA--

BLCAP for ontologies           About GeneDecksing


(SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for BLCAP
Interactions:

    Search GeneGlobe Interaction Network for BLCAP

STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

2 Interacting proteins for BLCAP (P629521 ENSP000003626374) via UniProtKB, MINT, STRING, and/or I2D
InteractantInteraction Details
GeneCardExternal ID(s)
ESR1P033721, ENSP000002062494EBI-3895726,EBI-78473 STRING: ENSP00000206249
ELAVL1ENSP000003852694STRING: ENSP00000385269
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Gene Ontology (GO): 2 biological process terms:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0007049cell cycle IEA--
GO:0030262apoptotic nuclear changes IDA17031575

BLCAP for ontologies           About GeneDecksing



(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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Browse Small Molecules at EMD Millipore
   Browse drugs & compounds from Enzo Life Sciences
  Browse compounds at ApexBio 

Browse Tocris compounds for BLCAP



(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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REFSEQ mRNAs for BLCAP gene (5 alternative transcripts): 
NM_001167820.1  NM_001167821.1  NM_001167822.1  NM_001167823.1  NM_006698.3  

Unigene Cluster for BLCAP:

Bladder cancer associated protein
Hs.472651  [show with all ESTs]
Unigene Representative Sequence: NM_001167820
13 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000411780 ENST00000447625 ENST00000467603 ENST00000397137(uc021wde.1 uc021wdf.1 uc002xhb.3)
ENST00000373537(uc002xhc.3) ENST00000397135 ENST00000397134 ENST00000397131
ENST00000432507 ENST00000445723 ENST00000414080 ENST00000456058 ENST00000414542(uc002xha.3)

miRNA
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Block miRNA regulation of human, mouse, rat BLCAP using miScript Target Protectors
Selected qRT-PCR Assays for microRNAs that regulate BLCAP (see all 81):
hsa-miR-607 hsa-miR-520e hsa-miR-519a hsa-miR-4274 hsa-miR-200b hsa-miR-130b hsa-miR-520b hsa-miR-130a*
SwitchGear 3'UTR luciferase reporter plasmidBLCAP 3' UTR sequence
Inhib. RNA
Products:
     
OriGene RNAi products in human, mouse, rat for BLCAP
Predesigned siRNA for gene silencing in human, mouse, rat BLCAP
Clone
Products:
     
OriGene clones in human, mouse for BLCAP (see all 24)
OriGene ORF clones in mouse, rat for BLCAP
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript: all cDNA clones in your preferred vector (see all 5): BLCAP (NM_006698)
DNA2.0 Custom Codon Optimized Gene Synthesis Service for BLCAP
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat BLCAP
Primer
Products:
    
OriGene qPCR primer pairs and template standards for BLCAP
OriGene qSTAR qPCR primer pairs in human, mouse for BLCAP
Search Pre-validated RT2 qPCR Primer Assays in human, mouse, rat BLCAP
  QuantiTect SYBR Green Assays in human, mouse, rat BLCAP
  QuantiFast Probe-based Assays in human, mouse, rat BLCAP

Additional mRNA sequence: 

AF053470.1 AK074498.1 AK124822.1 AL049288.1 BC047692.1 BC071704.1 

Selected DOTS entries (see all 28):

DT.75161816  DT.100805412  DT.95358487  DT.100823516  DT.100816553  DT.100823506  DT.120814301  DT.120814331 
DT.95166666  DT.100664452  DT.100823526  DT.120814283  DT.92415967  DT.100645682  DT.100823524  DT.120814277 
DT.120814289  DT.120814298  DT.120814407  DT.120814440  DT.91929558  DT.92035427  DT.92450736  DT.100687865 

Selected AceView cDNA sequences (see all 495):

BG402872 CB128256 BM844015 C05276 BM772584 BQ186271 BX388166 CR595359 
BG763756 BM909486 CR596766 CB215262 BM562736 BQ691432 BU196278 BQ880353 
BF792096 AA311080 BP375258 BQ936778 CR597740 BQ069521 BX107792 BQ073514 

GeneLoc Exon Structure

5 Alternative Splicing Database (ASD) splice patterns (SP) for BLCAP    About this scheme

ExUns: 1 ^ 2a · 2b · 2c ^ 3 ^ 4 ^ 5a · 5b · 5c
SP1:                                -                     
SP2:                                                      
SP3:        -     -     -     -     -                     
SP4:                    -     -     -                     
SP5:                          -     -                     


ECgene alternative splicing isoforms for BLCAP

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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BLCAP expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: CCTGTCCTTT
BLCAP Expression
About this image

BLCAP Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

BLCAP Protein Expression

SOURCE GeneReport for Unigene cluster: Hs.472651

UniProtKB/Swiss-Prot: BLCAP_HUMAN, P62952
Tissue specificity: Ubiquitous. Expressed in cervical tissues. Down-regulated in bladder invasive carcinoma, renal
cell carcinoma and in primary cervical carcinoma

    Custom PCR Arrays for BLCAP
Primer
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QuantiTect SYBR Green Assays in human, mouse, rat BLCAP
QuantiFast Probe-based Assays in human, mouse, rat BLCAP
In Situ
Assay Products:
 

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for BLCAP

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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This gene was present in the common ancestor of animals.

Orthologs for BLCAP gene from Selected species (see all 14)    About this table
Organism Taxonomic
classification
Gene Description Human
Similarity
Orthology
Type
Details
mouse
(Mus musculus)
Mammalia Blcap1 , 5 bladder cancer associated protein homolog (human)1, 5 95.02(n)1
100(a)1
  2 (78.40 cM)5
536191  NM_016916.31  NP_058612.31 
 1575563625 
chicken
(Gallus gallus)
Aves BLCAP1 bladder cancer associated protein 86.59(n)
94.25(a)
  100857695  XM_003642478.2  XP_003642526.2 
lizard
(Anolis carolinensis)
Reptilia BLCAP6
bladder cancer associated protein
94(a)
1 ↔ 1
GL343291.1(1565740-1566000)
African clawed frog
(Xenopus laevis)
Amphibia Xl.125252 Xenopus laevis transcribed sequence with strong similarity more 84.11(n)    BJ070504.1 
zebrafish
(Danio rerio)
Actinopterygii blcap2 bladder cancer associated protein 83.45(n)   57918  AB038320.1 
fruit fly
(Drosophila melanogaster)
Insecta bc106
bc10
61(a)
1 ↔ 1
3L(5558331-5559867)
worm
(Caenorhabditis elegans)
Secernentea Y73E7A.66
Protein Y73E7A.6 (Y73E7A.6) mRNA, complete cds
40(a)
1 ↔ 1
I(1607679-1610134) WBGene00022273


ENSEMBL Gene Tree for BLCAP (if available)
TreeFam Gene Tree for BLCAP (if available)

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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  --

(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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Selected SNPs for BLCAP (see all 152)    About this table    
Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 20 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
rs60632361,2
C,F,H--36145356(+) CTCTCG/AGCACT 5 -- ds50015Minor allele frequency- A:0.01NS EA NA 538
rs1460015711,2
--36145616(+) TCAGAC/GTCCCT 5 -- ds50010--------
rs1386496971,2
--36145767(+) AACTCC/TGAAAT 5 -- ds50010--------
rs1418687911,2
--36145863(+) TGCAAA/CGAACA 5 -- ut310--------
rs1926323851,2
--36145973(+) TGGCCA/CATCTC 5 -- ut310--------
rs3763303801,2
C--36145975(+) GGCCC-/TCCTCTC 5 -- ut310--------
rs37523111,2
C,F,H--36145996(+) GGCAAG/CAGAGA 5 -- ut31 ese3 trp35Minor allele frequency- C:0.01EA NS 1920
rs1174708921,2
C,F--36145998(+) CAAGAG/CAGAGA 5 -- ut311Minor allele frequency- C:0.02EA 120
rs1844793111,2
--36146042(+) ATCTCC/TAGCAG 5 -- ut310--------
rs1391242881,2
C--36146108(+) AGCAGC/TAAGTG 5 -- ut310--------

HapMap Linkage Disequilibrium report for BLCAP (36120874 - 36156333 bp)

Structural Variations
     Database of Genomic Variants (DGV) 1 variation for BLCAP:    About this table    
Variant IDTypeSubtypePubMed ID
nsv833968CNV Gain17160897

Site Specific Mutation Identification with PCR Assays
SeqTarget long-range PCR primers for resequencing BLCAP
DNA2.0 Custom Variant and Variant Library Synthesis for BLCAP

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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OMIM gene information: 613110    OMIM disorders: --

12 diseases for BLCAP:    About MalaCards
bladder transitional cell carcinoma    transitional cell carcinoma    intrahepatic cholangiocarcinoma    cholangiocarcinoma
renal cell carcinoma    astrocytoma    osteosarcoma    cervical cancer
cervicitis    colorectal cancer    malaria    breast cancer

1 disease from the University of Copenhagen DISEASES database for BLCAP:
Urinary bladder cancer

BLCAP for disorders           About GeneDecksing

2 Novoseek inferred disease relationships for BLCAP gene    About this table

Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
bladder cancer 57.8 3 8603421 (1), 11920613 (1), 19783793 (1)
tumors 11.2 6 16675915 (2), 11920613 (1), 19908260 (1), 19783793 (1)


Export disorders for BLCAP gene to outside databases

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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PubMed articles for BLCAP gene, integrated from 10 sources (see all 21):
(articles sorted by number of sources associating them with BLCAP)
    Utopia: connect your pdf to the dynamic
world of online information

  1. Identification of true differentially expressed mRNAs in a pair of human bladder transitional cell carcinomas using an improved differential display procedure. (PubMed id 10197429)1, 2, 3 Gromova I.... Celis J.E. (Electrophoresis 1999)
  2. Functional analysis of bladder cancer-related protein gene: a putative cervical cancer tumor suppressor gene in cervical carcinoma. (PubMed id 16675915)1, 2, 9 Zuo Z.... Wu X. (Tumor Biol. 2006)
  3. Human BLCAP transcript: new editing events in normal and cancerous tissues. (PubMed id 19908260)1, 2, 9 Galeano F.... Gallo A. (Int. J. Cancer 2010)
  4. Overexpression of BLCAP induces S phase arrest and apoptosis independent of p53 and NF-kappaB in human tongue carcinoma: BLCAP overexpression induces S phase arrest and apoptosis. (PubMed id 17031575)1, 2 Yao J.... Wu X. (Mol. Cell. Biochem. 2007)
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
  6. The DNA sequence and comparative analysis of human chromosome 20. (PubMed id 11780052)1, 2 Deloukas P....Rogers J. (Nature 2001)
  7. Bladder cancer-associated protein, a potential prognostic biomarker in human bladder cancer. (PubMed id 19783793)1, 9 Moreira J.M....Gromova I. (amp 2010)
  8. Transcript- and tissue-specific imprinting of a tumour suppressor gene. (PubMed id 18836209)1, 9 Schulz R....Oakey R.J. (Hum. Mol. Genet. 2009)
  9. Immunoexpression analysis and prognostic value of BLCAP in breast cancer. (PubMed id 23049907)1 Gromova I....Moreira J.M. (PLoS ONE 2012)
  10. Ubiquitin-mediated proteolysis of HuR by heat shock. (PubMed id 19322201)1 Abdelmohsen K....Gorospe M. (EMBO J. 2009)

(in PubMed, OMIM, and NCBI Bookshelf)
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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 10904 HGNC: 1055 AceView: BLCAP Ensembl:ENSG00000166619 euGenes: HUgn10904
ECgene: BLCAP H-InvDB: BLCAP

(According to HUGE)
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(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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NameDescription
PharmGKB entry for BLCAP Pharmacogenomics, SNPs, Pathways
ATLAS Chromosomes in Cancer entry for BLCAP Genetics and Cytogenetics in Oncology and Haematology

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
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Patent Information for BLCAP gene:
Search GeneIP for patents involving BLCAP

GeneCards and IP:
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(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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