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Aliases for BIVM-ERCC5 Gene

Aliases for BIVM-ERCC5 Gene

  • BIVM-ERCC5 Readthrough 2 3
  • BIVM-ERCC5 Protein 3
  • ERCC5-202 3

External Ids for BIVM-ERCC5 Gene

Previous GeneCards Identifiers for BIVM-ERCC5 Gene

  • GC13U900839
  • GC13P103460
  • GC13P103461

Summaries for BIVM-ERCC5 Gene

Entrez Gene Summary for BIVM-ERCC5 Gene

  • This locus represents naturally occurring read-through transcription between the neighboring BIVM (basic, immunoglobulin-like variable motif containing) and ERCC5 (excision repair cross-complementing rodent repair deficiency, complementation group 5) genes on chromosome 13. The read-through transcript encodes a fusion protein that shares sequence identity with the products of each individual gene. [provided by RefSeq, Feb 2011]

GeneCards Summary for BIVM-ERCC5 Gene

BIVM-ERCC5 (BIVM-ERCC5 Readthrough) is a Protein Coding gene. Among its related pathways are Global Genomic NER (GG-NER). An important paralog of this gene is ERCC5.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for BIVM-ERCC5 Gene

Genomics for BIVM-ERCC5 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for BIVM-ERCC5 Gene

102,807,146 bp from pter
102,876,001 bp from pter
68,856 bases
Plus strand

Genomic View for BIVM-ERCC5 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for BIVM-ERCC5 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for BIVM-ERCC5 Gene

No data available for Regulatory Elements for BIVM-ERCC5 Gene

Proteins for BIVM-ERCC5 Gene

  • Protein details for BIVM-ERCC5 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    Recommended name:
    Protein BIVM-ERCC5
    Protein Accession:
    Secondary Accessions:

    Protein attributes for BIVM-ERCC5 Gene

    1385 amino acids
    Molecular mass:
    156070 Da
    Quaternary structure:
    No Data Available

neXtProt entry for BIVM-ERCC5 Gene

Proteomics data for BIVM-ERCC5 Gene at MOPED

Post-translational modifications for BIVM-ERCC5 Gene

No Post-translational modifications

Other Protein References for BIVM-ERCC5 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for BIVM-ERCC5 Gene

Domains for BIVM-ERCC5 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with BIVM-ERCC5: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for BIVM-ERCC5 Gene

Function for BIVM-ERCC5 Gene

Gene Ontology (GO) - Molecular Function for BIVM-ERCC5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding --
GO:0003697 single-stranded DNA binding --
GO:0003824 catalytic activity --
GO:0004518 nuclease activity --
GO:0004519 endonuclease activity --
genes like me logo Genes that share ontologies with BIVM-ERCC5: view

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for BIVM-ERCC5 Gene

Localization for BIVM-ERCC5 Gene

Gene Ontology (GO) - Cellular Components for BIVM-ERCC5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus --
genes like me logo Genes that share ontologies with BIVM-ERCC5: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Subcellular locations from COMPARTMENTS for BIVM-ERCC5 Gene

Pathways for BIVM-ERCC5 Gene

SuperPathways for BIVM-ERCC5 Gene

Superpath Contained pathways
1 Global Genomic NER (GG-NER)
genes like me logo Genes that share pathways with BIVM-ERCC5: view

Pathways by source for BIVM-ERCC5 Gene

1 KEGG pathway for BIVM-ERCC5 Gene

Interacting Proteins for BIVM-ERCC5 Gene

Gene Ontology (GO) - Biological Process for BIVM-ERCC5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006281 DNA repair --
GO:0006289 nucleotide-excision repair --
genes like me logo Genes that share ontologies with BIVM-ERCC5: view

Transcripts for BIVM-ERCC5 Gene


(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for BIVM-ERCC5 Gene

No ASD Table

Relevant External Links for BIVM-ERCC5 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for BIVM-ERCC5 Gene

No Expression Related Data Available

Primer Products

In Situ Assay Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Expression partners for BIVM-ERCC5 Gene

Orthologs for BIVM-ERCC5 Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for BIVM-ERCC5 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia ERCC5 36
  • 69 (a)
(Canis familiaris)
Mammalia BIVM 36
  • 71 (a)
(Mus musculus)
Mammalia Ercc5 36
  • 56 (a)
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 49 (a)
(Pan troglodytes)
Mammalia BIVM-ERCC5 36
  • 84 (a)
(Gallus gallus)
Aves ERCC5 36
  • 45 (a)
(Anolis carolinensis)
Reptilia -- 36
  • 47 (a)
(Danio rerio)
Actinopterygii ercc5 36
  • 38 (a)
fruit fly
(Drosophila melanogaster)
Insecta mus201 36
  • 21 (a)
(Caenorhabditis elegans)
Secernentea gen-1 36
  • 21 (a)
xpg-1 36
  • 20 (a)
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes RAD2 36
  • 21 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 29 (a)
Species with no ortholog for BIVM-ERCC5:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)

Evolution for BIVM-ERCC5 Gene

Gene Tree for BIVM-ERCC5 (if available)
Gene Tree for BIVM-ERCC5 (if available)

Paralogs for BIVM-ERCC5 Gene

Paralogs for BIVM-ERCC5 Gene

(3) SIMAP similar genes for BIVM-ERCC5 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with BIVM-ERCC5: view

Variants for BIVM-ERCC5 Gene

Sequence variations from dbSNP and Humsavar for BIVM-ERCC5 Gene

SNP ID Clin Chr 13 pos Sequence Context AA Info Type MAF
rs1985702 -- 102,842,774(-) CGCCT(A/G)TAATC intron-variant
rs4400916 -- 102,842,421(+) CTTTA(G/T)ATAGC intron-variant
rs7316963 -- 102,842,294(+) AATTT(C/G)AAGAA intron-variant
rs34973231 -- 102,843,514(+) ATTTA(-/G)GGGCC intron-variant
rs77560234 -- 102,843,644(+) ACAAG(A/G)CAACA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for BIVM-ERCC5 Gene

Variant ID Type Subtype PubMed ID
nsv900972 CNV Loss 21882294
esv2661939 CNV Deletion 23128226

Relevant External Links for BIVM-ERCC5 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for BIVM-ERCC5 Gene

Disorders for BIVM-ERCC5 Gene

No disorders were found for BIVM-ERCC5 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for BIVM-ERCC5 Gene

Publications for BIVM-ERCC5 Gene

  1. Expression of conjoined genes: another mechanism for gene regulation in eukaryotes. (PMID: 20967262) Prakash T. … Taylor T.D. (PLoS ONE 2010) 3
  2. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PMID: 21890473) Wagner S.A. … Choudhary C. (Mol. Cell Proteomics 2011) 3
  3. Global identification of modular cullin-RING ligase substrates. (PMID: 21963094) Emanuele M.J. … Elledge S.J. (Cell 2011) 3
  4. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PMID: 23000965) Povlsen L.K. … Choudhary C. (Nat. Cell Biol. 2012) 3

Products for BIVM-ERCC5 Gene

Sources for BIVM-ERCC5 Gene

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