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Aliases for BIVM Gene

Aliases for BIVM Gene

  • Basic, Immunoglobulin-Like Variable Motif Containing 2 3 5

External Ids for BIVM Gene

Previous GeneCards Identifiers for BIVM Gene

  • GC13P101819
  • GC13P097838
  • GC13P102288
  • GC13P101149
  • GC13P102249
  • GC13P103451
  • GC13P084043

Summaries for BIVM Gene

GeneCards Summary for BIVM Gene

BIVM (Basic, Immunoglobulin-Like Variable Motif Containing) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for BIVM Gene

Genomics for BIVM Gene

Regulatory Elements for BIVM Gene

Enhancers for BIVM Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
- Elite enhancer/Elite enhancer-gene association

Enhancers around BIVM on UCSC Golden Path with GeneCards custom track

Promoters for BIVM Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

Genomic Location for BIVM Gene

102,799,049 bp from pter
102,841,538 bp from pter
42,490 bases
Plus strand

Genomic View for BIVM Gene

Genes around BIVM on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
BIVM Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for BIVM Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for BIVM Gene

Proteins for BIVM Gene

  • Protein details for BIVM Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Basic immunoglobulin-like variable motif-containing protein
    Protein Accession:
    Secondary Accessions:
    • Q2M1J2
    • Q9NXM4

    Protein attributes for BIVM Gene

    503 amino acids
    Molecular mass:
    56774 Da
    Quaternary structure:
    No Data Available
    • Sequence=AAH51813.2; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=BAA90986.1; Type=Erroneous initiation; Evidence={ECO:0000305};

    Alternative splice isoforms for BIVM Gene


neXtProt entry for BIVM Gene

Post-translational modifications for BIVM Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for BIVM Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for BIVM Gene

Domains & Families for BIVM Gene

Protein Domains for BIVM Gene


Suggested Antigen Peptide Sequences for BIVM Gene

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the BIVM family.
  • Belongs to the BIVM family.
genes like me logo Genes that share domains with BIVM: view

No data available for Gene Families for BIVM Gene

Function for BIVM Gene

Phenotypes for BIVM Gene

genes like me logo Genes that share phenotypes with BIVM: view

Animal Models for BIVM Gene

MGI Knock Outs for BIVM:
  • Bivm tm1b(KOMP)Wtsi

Animal Model Products

CRISPR Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for BIVM Gene

Localization for BIVM Gene

Subcellular locations from UniProtKB/Swiss-Prot for BIVM Gene

Cytoplasm. Nucleus.

Subcellular locations from

Jensen Localization Image for BIVM Gene COMPARTMENTS Subcellular localization image for BIVM gene
Compartment Confidence
extracellular 5
nucleus 4
cytosol 2
golgi apparatus 2

Gene Ontology (GO) - Cellular Components for BIVM Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005615 extracellular space IDA 23580065
GO:0005634 nucleus IEA --
GO:0005737 cytoplasm IEA --
genes like me logo Genes that share ontologies with BIVM: view

Pathways & Interactions for BIVM Gene

SuperPathways for BIVM Gene

No Data Available

Interacting Proteins for BIVM Gene

STRING Interaction Network Preview (showing 2 interactants - click image to see details)
Selected Interacting proteins: ENSP00000257336 Q86UB2-BIVM_HUMAN for BIVM Gene via STRING IID

Gene Ontology (GO) - Biological Process for BIVM Gene


No data available for Pathways by source and SIGNOR curated interactions for BIVM Gene

Drugs & Compounds for BIVM Gene

No Compound Related Data Available

Transcripts for BIVM Gene

Unigene Clusters for BIVM Gene

Basic, immunoglobulin-like variable motif containing:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for BIVM Gene

ExUns: 1a · 1b · 1c · 1d · 1e · 1f · 1g ^ 2 ^ 3a · 3b ^ 4a · 4b ^ 5 ^ 6 ^ 7a · 7b · 7c · 7d ^ 8a · 8b · 8c · 8d · 8e · 8f ^ 9a · 9b ^
SP1: - - - - - -
SP5: - - - - - - - - - - - - - - - - -
SP7: - - - - - - -
SP8: - - - - -
SP9: - - - - -
SP10: - - - - - - - - - - -
SP11: - - - - - - - - - -
SP13: - - - - -
SP14: - - -
SP15: - - - - - - - -
SP16: - - - - - - -
SP17: - - - - - - - - - - -

ExUns: 10 ^ 11a · 11b ^ 12 ^ 13a · 13b ^ 14a · 14b ^ 15 ^ 16 ^ 17 ^ 18a · 18b · 18c · 18d
SP1: - - -
SP2: - - - - -
SP3: -
SP4: -
SP5: - -
SP6: -

Relevant External Links for BIVM Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for BIVM Gene

mRNA expression in normal human tissues for BIVM Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for BIVM Gene

This gene is overexpressed in Urine (54.6) and Fetal heart (14.4).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for BIVM Gene

Protein tissue co-expression partners for BIVM Gene

NURSA nuclear receptor signaling pathways regulating expression of BIVM Gene:


SOURCE GeneReport for Unigene cluster for BIVM Gene:


mRNA Expression by UniProt/SwissProt for BIVM Gene:

Tissue specificity: Widely expressed. Expressed at higher level in spleen, ovary, small intestine, colon, peripheral blood leukocytes and liver. Also expressed in testis, ovary, aorta, appendix, trachea, pituitary gland, bladder, uterus, spinal cord, salivary gland, stomach, mammary gland and bone marrow. Weakly or not expressed in fetal spleen, adult thymus and certain cancer cell lines.
genes like me logo Genes that share expression patterns with BIVM: view

Primer Products

No data available for mRNA differential expression in normal tissues for BIVM Gene

Orthologs for BIVM Gene

This gene was present in the common ancestor of chordates.

Orthologs for BIVM Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia BIVM 34
  • 90.9 (n)
  • 92.83 (a)
(Canis familiaris)
Mammalia BIVM 34
  • 93.8 (n)
  • 98.91 (a)
(Mus musculus)
Mammalia Bivm 34
  • 87.12 (n)
  • 87.65 (a)
Bivm 16
Bivm 35
  • 88 (a)
(Pan troglodytes)
Mammalia BIVM 34
  • 99.14 (n)
  • 99.2 (a)
(Rattus norvegicus)
Mammalia LOC102548228 34
  • 87.38 (n)
  • 87.85 (a)
(Monodelphis domestica)
Mammalia BIVM 35
  • 86 (a)
(Ornithorhynchus anatinus)
Mammalia BIVM 35
  • 88 (a)
(Gallus gallus)
Aves BIVM 34
  • 76.58 (n)
  • 77.05 (a)
  • 76 (a)
(Anolis carolinensis)
Reptilia BIVM 35
  • 73 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia bivm 34
  • 69.89 (n)
  • 68.81 (a)
African clawed frog
(Xenopus laevis)
Amphibia bivm-A-prov 34
(Danio rerio)
Actinopterygii bivm 34
bivm 35
  • 55 (a)
Species where no ortholog for BIVM was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for BIVM Gene

Gene Tree for BIVM (if available)
Gene Tree for BIVM (if available)

Paralogs for BIVM Gene

(1) SIMAP similar genes for BIVM Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with BIVM: view

No data available for Paralogs for BIVM Gene

Variants for BIVM Gene

Sequence variations from dbSNP and Humsavar for BIVM Gene

SNP ID Clin Chr 13 pos Sequence Context AA Info Type
rs2031645 -- 102,804,781(+) GAATA(C/G)AGAAA intron-variant
rs7326915 -- 102,801,263(+) TTTTT(C/T)TGAGA intron-variant
rs7492173 -- 102,803,450(+) gtgag(C/T)tgaga intron-variant
rs9518840 -- 102,801,969(+) GGGGG(A/G)TGGGG intron-variant
rs9514058 -- 102,802,019(+) CCATC(A/T)GGAGT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for BIVM Gene

Variant ID Type Subtype PubMed ID
nsv1048497 CNV gain 25217958
nsv562981 CNV gain 21841781

Variation tolerance for BIVM Gene

Residual Variation Intolerance Score: 21.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.27; 25.42% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for BIVM Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for BIVM Gene

Disorders for BIVM Gene

Relevant External Links for BIVM

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator
Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for BIVM Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for BIVM Gene

Publications for BIVM Gene

  1. BIVM, a novel gene widely distributed among deuterostomes, shares a core sequence with an unusual gene in Giardia lamblia. (PMID: 12036287) Yoder J.A. … Litman G.W. (Genomics 2002) 2 3 4 65
  2. Association between genetic variants in VEGF, ERCC3 and occupational benzene haematotoxicity. (PMID: 19773279) Hosgood H.D. … Lan Q. (Occup Environ Med 2009) 3 46 65
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 65
  4. Shotgun proteomics reveals specific modulated protein patterns in tears of patients with primary open angle glaucoma naA^ve to therapy. (PMID: 23580065) Pieragostino D. … Del Boccio P. (Mol Biosyst 2013) 3 65
  5. Ubiquitin-mediated proteolysis of HuR by heat shock. (PMID: 19322201) Abdelmohsen K. … Gorospe M. (EMBO J. 2009) 3 65

Products for BIVM Gene

Sources for BIVM Gene

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