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Aliases for BIVM Gene

Aliases for BIVM Gene

  • Basic, Immunoglobulin-Like Variable Motif Containing 2 3

External Ids for BIVM Gene

Previous GeneCards Identifiers for BIVM Gene

  • GC13P101819
  • GC13P097838
  • GC13P102288
  • GC13P101149
  • GC13P102249
  • GC13P103451
  • GC13P084043

Summaries for BIVM Gene

GeneCards Summary for BIVM Gene

BIVM (Basic, Immunoglobulin-Like Variable Motif Containing) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for BIVM Gene

Genomics for BIVM Gene

Regulatory Elements for BIVM Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for BIVM Gene

Start:
102,799,049 bp from pter
End:
102,841,538 bp from pter
Size:
42,490 bases
Orientation:
Plus strand

Genomic View for BIVM Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for BIVM Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for BIVM Gene

Proteins for BIVM Gene

  • Protein details for BIVM Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q86UB2-BIVM_HUMAN
    Recommended name:
    Basic immunoglobulin-like variable motif-containing protein
    Protein Accession:
    Q86UB2
    Secondary Accessions:
    • Q2M1J2
    • Q9NXM4

    Protein attributes for BIVM Gene

    Size:
    503 amino acids
    Molecular mass:
    56774 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAH51813.2; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=BAA90986.1; Type=Erroneous initiation; Evidence={ECO:0000305};

    Alternative splice isoforms for BIVM Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for BIVM Gene

Proteomics data for BIVM Gene at MOPED

Post-translational modifications for BIVM Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for BIVM Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for BIVM Gene

Domains for BIVM Gene

Protein Domains for BIVM Gene

ProtoNet:

Suggested Antigen Peptide Sequences for BIVM Gene

Graphical View of Domain Structure for InterPro Entry

Q86UB2

UniProtKB/Swiss-Prot:

BIVM_HUMAN :
  • Q86UB2
Family:
  • Belongs to the BIVM family.
genes like me logo Genes that share domains with BIVM: view

No data available for Gene Families for BIVM Gene

Function for BIVM Gene

Animal Model Products

miRNA for BIVM Gene

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for BIVM

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for BIVM Gene

Localization for BIVM Gene

Subcellular locations from UniProtKB/Swiss-Prot for BIVM Gene

Cytoplasm. Nucleus.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for BIVM Gene COMPARTMENTS Subcellular localization image for BIVM gene
Compartment Confidence
nucleus 5
cytosol 2
golgi apparatus 2

Gene Ontology (GO) - Cellular Components for BIVM Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005615 extracellular space IDA 23580065
GO:0005634 nucleus IEA --
GO:0005737 cytoplasm IEA --
genes like me logo Genes that share ontologies with BIVM: view

Pathways for BIVM Gene

SuperPathways for BIVM Gene

No Data Available

Interacting Proteins for BIVM Gene

STRING Interaction Network Preview (showing 2 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000257336%0d%0a9606.ENSP00000347978%0d%0a9606.ENSP00000385269%0d%0a
Selected Interacting proteins: ENSP00000257336 for BIVM Gene via STRING

Gene Ontology (GO) - Biological Process for BIVM Gene

None

No data available for Pathways by source for BIVM Gene

Transcripts for BIVM Gene

Unigene Clusters for BIVM Gene

Basic, immunoglobulin-like variable motif containing:
Representative Sequences:

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for BIVM

Primer Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for BIVM Gene

ExUns: 1a · 1b · 1c · 1d · 1e · 1f · 1g ^ 2 ^ 3a · 3b ^ 4a · 4b ^ 5 ^ 6 ^ 7a · 7b · 7c · 7d ^ 8a · 8b · 8c · 8d · 8e · 8f ^ 9a · 9b ^
SP1: - - - - - -
SP2:
SP3:
SP4:
SP5: - - - - - - - - - - - - - - - - -
SP6:
SP7: - - - - - - -
SP8: - - - - -
SP9: - - - - -
SP10: - - - - - - - - - - -
SP11: - - - - - - - - - -
SP12:
SP13: - - - - -
SP14: - - -
SP15: - - - - - - - -
SP16: - - - - - - -
SP17: - - - - - - - - - - -
SP18:

ExUns: 10 ^ 11a · 11b ^ 12 ^ 13a · 13b ^ 14a · 14b ^ 15 ^ 16 ^ 17 ^ 18a · 18b · 18c · 18d
SP1: - - -
SP2: - - - - -
SP3: -
SP4: -
SP5: - -
SP6: -
SP7:
SP8:
SP9:
SP10:
SP11:
SP12:
SP13:
SP14:
SP15:
SP16:
SP17:
SP18:

Relevant External Links for BIVM Gene

GeneLoc Exon Structure for
BIVM
ECgene alternative splicing isoforms for
BIVM

Expression for BIVM Gene

mRNA expression in normal human tissues for BIVM Gene

Protein differential expression in normal tissues for BIVM Gene

This gene is overexpressed in Urine (54.6) and Fetal heart (14.4).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for BIVM Gene

SOURCE GeneReport for Unigene cluster for BIVM Gene Hs.288809

mRNA Expression by UniProt/SwissProt for BIVM Gene

Q86UB2-BIVM_HUMAN
Tissue specificity: Widely expressed. Expressed at higher level in spleen, ovary, small intestine, colon, peripheral blood leukocytes and liver. Also expressed in testis, ovary, aorta, appendix, trachea, pituitary gland, bladder, uterus, spinal cord, salivary gland, stomach, mammary gland and bone marrow. Weakly or not expressed in fetal spleen, adult thymus and certain cancer cell lines.
genes like me logo Genes that share expressions with BIVM: view

Expression partners for BIVM Gene

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA differential expression in normal tissues for BIVM Gene

Orthologs for BIVM Gene

This gene was present in the common ancestor of chordates.

Orthologs for BIVM Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia BIVM 35
  • 90.9 (n)
  • 92.83 (a)
dog
(Canis familiaris)
Mammalia BIVM 35
  • 93.8 (n)
  • 98.91 (a)
mouse
(Mus musculus)
Mammalia Bivm 35
  • 87.12 (n)
  • 87.65 (a)
Bivm 16
Bivm 36
  • 88 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia BIVM 35
  • 99.14 (n)
  • 99.2 (a)
rat
(Rattus norvegicus)
Mammalia LOC102548228 35
  • 87.38 (n)
  • 87.85 (a)
oppossum
(Monodelphis domestica)
Mammalia BIVM 36
  • 86 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia BIVM 36
  • 88 (a)
OneToOne
chicken
(Gallus gallus)
Aves BIVM 35
  • 76.58 (n)
  • 77.05 (a)
BIVM 36
  • 76 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia BIVM 36
  • 73 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia bivm 35
  • 69.89 (n)
  • 68.81 (a)
African clawed frog
(Xenopus laevis)
Amphibia bivm-A-prov 35
zebrafish
(Danio rerio)
Actinopterygii bivm 35
bivm 36
  • 55 (a)
OneToOne
Species with no ortholog for BIVM:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for BIVM Gene

ENSEMBL:
Gene Tree for BIVM (if available)
TreeFam:
Gene Tree for BIVM (if available)

Paralogs for BIVM Gene

Selected SIMAP similar genes for BIVM Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with BIVM: view

No data available for Paralogs for BIVM Gene

Variants for BIVM Gene

Sequence variations from dbSNP and Humsavar for BIVM Gene

SNP ID Clin Chr 13 pos Sequence Context AA Info Type MAF
rs2031645 -- 102,804,781(+) GAATA(C/G)AGAAA intron-variant
rs4387459 -- 102,804,872(+) TCCAT(C/G)AAAGC intron-variant
rs7326915 -- 102,801,263(+) TTTTT(C/T)TGAGA intron-variant
rs7492173 -- 102,803,450(+) gtgag(C/T)tgaga intron-variant
rs9514058 -- 102,802,019(+) CCATC(A/T)GGAGT intron-variant

Relevant External Links for BIVM Gene

HapMap Linkage Disequilibrium report
BIVM

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for BIVM Gene

Disorders for BIVM Gene

Relevant External Links for BIVM

Genetic Association Database (GAD)
BIVM
Human Genome Epidemiology (HuGE) Navigator
BIVM

No disorders were found for BIVM Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships and Genatlas for BIVM Gene

Publications for BIVM Gene

  1. BIVM, a novel gene widely distributed among deuterostomes, shares a core sequence with an unusual gene in Giardia lamblia. (PMID: 12036287) Yoder J.A. … Litman G.W. (Genomics 2002) 2 3 4
  2. Association between genetic variants in VEGF, ERCC3 and occupational benzene haematotoxicity. (PMID: 19773279) Hosgood H.D. … Lan Q. (Occup Environ Med 2009) 3 48
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  4. Ubiquitin-mediated proteolysis of HuR by heat shock. (PMID: 19322201) Abdelmohsen K. … Gorospe M. (EMBO J. 2009) 3
  5. The transcriptome of human CD34+ hematopoietic stem-progenitor cells. (PMID: 19416867) Kim Y.C. … Wang S.M. (Proc. Natl. Acad. Sci. U.S.A. 2009) 3

Products for BIVM Gene

Sources for BIVM Gene

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