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Aliases for BIRC3 Gene

Aliases for BIRC3 Gene

  • Baculoviral IAP Repeat Containing 3 2 3 5
  • Inhibitor Of Apoptosis Protein 1 2 3 4
  • Apoptosis Inhibitor 2 2 3 4
  • RING-Type E3 Ubiquitin Transferase BIRC3 3 4
  • TNFR2-TRAF-Signaling Complex Protein 1 3 4
  • TNFR2-TRAF Signaling Complex Protein 2 3
  • Cellular Inhibitor Of Apoptosis 2 3 4
  • Mammalian IAP Homolog C 2 3
  • RING Finger Protein 49 3 4
  • IAP Homolog C 3 4
  • C-IAP2 3 4
  • HIAP1 3 4
  • RNF49 3 4
  • API2 3 4
  • MIHC 3 4
  • Baculoviral IAP Repeat-Containing Protein 3 3
  • Baculoviral IAP Repeat-Containing 3 2
  • EC 2.3.2.27 4
  • HIAP-1 4
  • CIAP2 3
  • HAIP1 3
  • IAP-1 3
  • MALT2 3
  • AIP1 3

External Ids for BIRC3 Gene

Previous HGNC Symbols for BIRC3 Gene

  • API2

Previous GeneCards Identifiers for BIRC3 Gene

  • GC11P104381
  • GC11P103545
  • GC11P102222
  • GC11P101725
  • GC11P101693
  • GC11P098114
  • GC11P102188

Summaries for BIRC3 Gene

Entrez Gene Summary for BIRC3 Gene

  • This gene encodes a member of the IAP family of proteins that inhibit apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. The encoded protein inhibits apoptosis induced by serum deprivation but does not affect apoptosis resulting from exposure to menadione, a potent inducer of free radicals. It contains 3 baculovirus IAP repeats and a ring finger domain. Transcript variants encoding the same isoform have been identified. [provided by RefSeq, Aug 2011]

CIViC summary for BIRC3 Gene

GeneCards Summary for BIRC3 Gene

BIRC3 (Baculoviral IAP Repeat Containing 3) is a Protein Coding gene. Diseases associated with BIRC3 include Lymphoma, Malt, Somatic and B-Cell Lymphoma Of Mucosa-Associated Lymphoid Tissue. Among its related pathways are TRAF Pathway and Apoptosis and survival Caspase cascade. GO annotations related to this gene include ligase activity and cysteine-type endopeptidase inhibitor activity involved in apoptotic process. An important paralog of this gene is BIRC2.

UniProtKB/Swiss-Prot for BIRC3 Gene

  • Multi-functional protein which regulates not only caspases and apoptosis, but also modulates inflammatory signaling and immunity, mitogenic kinase signaling and cell proliferation, as well as cell invasion and metastasis. Acts as an E3 ubiquitin-protein ligase regulating NF-kappa-B signaling and regulates both canonical and non-canonical NF-kappa-B signaling by acting in opposite directions: acts as a positive regulator of the canonical pathway and suppresses constitutive activation of non-canonical NF-kappa-B signaling. The target proteins for its E3 ubiquitin-protein ligase activity include: RIPK1, RIPK2, RIPK3, RIPK4, CASP3, CASP7, CASP8, IKBKE, TRAF1, and BCL10. Acts as an important regulator of innate immune signaling via regulation of Toll-like receptors (TLRs), Nodlike receptors (NLRs) and RIG-I like receptors (RLRs), collectively referred to as pattern recognition receptors (PRRs). Protects cells from spontaneous formation of the ripoptosome, a large multi-protein complex that has the capability to kill cancer cells in a caspase-dependent and caspase-independent manner. Suppresses ripoptosome formation by ubiquitinating RIPK1 and CASP8.

Gene Wiki entry for BIRC3 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for BIRC3 Gene

Genomics for BIRC3 Gene

Regulatory Elements for BIRC3 Gene

Enhancers for BIRC3 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH11G102311 2 FANTOM5 Ensembl ENCODE dbSUPER 23.4 +0.3 290 13.2 HDGF HNRNPUL1 PKNOX1 FOXA2 MLX WRNIP1 SIN3A ARID4B FEZF1 ZNF2 BIRC2 BIRC3 ENSG00000256916 MMP20 MMP7 TMEM123
GH11G102303 1.8 FANTOM5 Ensembl ENCODE dbSUPER 19.5 -11.5 -11453 4.7 PKNOX1 FOXA2 ARID4B FOS REST NFIL3 MAFF MIER3 ETV4 STAT3 BIRC3 BIRC2 MMP7 ENSG00000270868 RPS6P17
GH11G102287 1.3 Ensembl ENCODE dbSUPER 20.4 -28.4 -28351 3.8 CTCF SAP130 ARID4B RAD21 RFX5 ZNF143 SMC3 RELB DEK GATAD2A BIRC3 RPS6P17 LOC105369460
GH11G102293 1.3 Ensembl ENCODE dbSUPER 20 -22.5 -22465 2.5 CTCF PKNOX1 ARID4B ZNF2 RAD21 RFX5 ZNF143 SMC3 RELB IKZF2 BIRC3 BIRC2 RPS6P17 LOC105369460
GH11G102341 1.5 Ensembl ENCODE dbSUPER 12.1 +24.5 24503 0.7 HDGF PKNOX1 ATF1 ARNT WRNIP1 ARID4B SIN3A E2F7 ZNF2 TCF12 BIRC3 RNU6-952P TMEM123 BIRC2
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around BIRC3 on UCSC Golden Path with GeneCards custom track

Promoters for BIRC3 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000265604 327 1401 HDGF PKNOX1 FOXA2 WRNIP1 SIN3A FEZF1 ZNF2 YY1 ZNF143 ZNF207
ENSR00000044006 1527 201 CTCF MXI1 ZBED1 TARDBP CHD1 RCOR1 IKZF2 SPI1 RELA

Genomic Location for BIRC3 Gene

Chromosome:
11
Start:
102,317,373 bp from pter
End:
102,339,403 bp from pter
Size:
22,031 bases
Orientation:
Plus strand

Genomic View for BIRC3 Gene

Genes around BIRC3 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
BIRC3 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for BIRC3 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for BIRC3 Gene

Proteins for BIRC3 Gene

  • Protein details for BIRC3 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q13489-BIRC3_HUMAN
    Recommended name:
    Baculoviral IAP repeat-containing protein 3
    Protein Accession:
    Q13489
    Secondary Accessions:
    • Q16628
    • Q9HC27
    • Q9UP46

    Protein attributes for BIRC3 Gene

    Size:
    604 amino acids
    Molecular mass:
    68372 Da
    Quaternary structure:
    • Interacts with DIABLO/SMAC and with PRSS25; these interactions inhibit apoptotic suppressor activity. The BIR motifs region interacts with TNF receptor associated factors 1 and 2 (TRAF1 and TRAF2) to form a heteromeric complex, which is then recruited to the tumor necrosis factor receptor 2 (TNFR2). Interaction with TRAF2 is required for ubiquitination of IKBKE, degradation of NFKBIA and activation of NF-kappa-B. Interacts with RIP1, RIP2, RIP3, RIP4 and USP19.

    Three dimensional structures from OCA and Proteopedia for BIRC3 Gene

neXtProt entry for BIRC3 Gene

Post-translational modifications for BIRC3 Gene

  • Auto-ubiquitinated and degraded by the proteasome in apoptotic cells.
  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for BIRC3 Gene

Antibody Products

  • R&D Systems Antibodies for BIRC3 (cIAP-2/HIAP-1)
  • Cell Signaling Technology (CST) Antibodies for BIRC3 (cIAP2)
  • Abcam antibodies for BIRC3

No data available for DME Specific Peptides for BIRC3 Gene

Domains & Families for BIRC3 Gene

Suggested Antigen Peptide Sequences for BIRC3 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q13489

UniProtKB/Swiss-Prot:

BIRC3_HUMAN :
  • Belongs to the IAP family.
Family:
  • Belongs to the IAP family.
genes like me logo Genes that share domains with BIRC3: view

Function for BIRC3 Gene

Molecular function for BIRC3 Gene

UniProtKB/Swiss-Prot CatalyticActivity:
S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.
UniProtKB/Swiss-Prot EnzymeRegulation:
USP19 regulates the stability of BIRC3/c-IAP2 by preventing its ubiquitination.
UniProtKB/Swiss-Prot Function:
Multi-functional protein which regulates not only caspases and apoptosis, but also modulates inflammatory signaling and immunity, mitogenic kinase signaling and cell proliferation, as well as cell invasion and metastasis. Acts as an E3 ubiquitin-protein ligase regulating NF-kappa-B signaling and regulates both canonical and non-canonical NF-kappa-B signaling by acting in opposite directions: acts as a positive regulator of the canonical pathway and suppresses constitutive activation of non-canonical NF-kappa-B signaling. The target proteins for its E3 ubiquitin-protein ligase activity include: RIPK1, RIPK2, RIPK3, RIPK4, CASP3, CASP7, CASP8, IKBKE, TRAF1, and BCL10. Acts as an important regulator of innate immune signaling via regulation of Toll-like receptors (TLRs), Nodlike receptors (NLRs) and RIG-I like receptors (RLRs), collectively referred to as pattern recognition receptors (PRRs). Protects cells from spontaneous formation of the ripoptosome, a large multi-protein complex that has the capability to kill cancer cells in a caspase-dependent and caspase-independent manner. Suppresses ripoptosome formation by ubiquitinating RIPK1 and CASP8.

Enzyme Numbers (IUBMB) for BIRC3 Gene

Gene Ontology (GO) - Molecular Function for BIRC3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004842 ubiquitin-protein transferase activity TAS --
GO:0005515 protein binding IPI 11907583
GO:0008270 zinc ion binding IEA --
GO:0016740 transferase activity EXP 19008929
GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process IBA --
genes like me logo Genes that share ontologies with BIRC3: view
genes like me logo Genes that share phenotypes with BIRC3: view

Human Phenotype Ontology for BIRC3 Gene

HPO Id HPO Name Alternative Ids Definition Synonyms

Animal Models for BIRC3 Gene

MGI Knock Outs for BIRC3:

Animal Model Products

CRISPR Products

miRNA for BIRC3 Gene

Inhibitory RNA Products

Clone Products

  • Addgene plasmids for BIRC3

No data available for Transcription Factor Targets and HOMER Transcription for BIRC3 Gene

Localization for BIRC3 Gene

Subcellular locations from UniProtKB/Swiss-Prot for BIRC3 Gene

Cytoplasm. Nucleus.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for BIRC3 gene
Compartment Confidence
nucleus 5
cytosol 5
mitochondrion 2
plasma membrane 1
extracellular 1
peroxisome 1
endoplasmic reticulum 1
golgi apparatus 1

Gene Ontology (GO) - Cellular Components for BIRC3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA,IDA 15665297
GO:0005654 nucleoplasm IDA --
GO:0005737 cytoplasm IDA,IEA 15665297
GO:0005829 cytosol TAS --
GO:0043234 protein complex IEA --
genes like me logo Genes that share ontologies with BIRC3: view

Pathways & Interactions for BIRC3 Gene

genes like me logo Genes that share pathways with BIRC3: view

SIGNOR curated interactions for BIRC3 Gene

Activates:
Inactivates:
Is activated by:
Is inactivated by:

Gene Ontology (GO) - Biological Process for BIRC3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006915 apoptotic process IEA --
GO:0007166 cell surface receptor signaling pathway TAS 8548810
GO:0007249 I-kappaB kinase/NF-kappaB signaling TAS --
GO:0007283 spermatogenesis IEA --
GO:0010803 regulation of tumor necrosis factor-mediated signaling pathway TAS --
genes like me logo Genes that share ontologies with BIRC3: view

Drugs & Compounds for BIRC3 Gene

(33) Drugs for BIRC3 Gene - From: ApexBio, DGIdb, and Novoseek

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
GDC-0152 Pharma IAP antagonist,potent amd samll-molecule 0
LCL161 Pharma Antagonist Antagonist of IAPs inhibitor, Inhibitor of apoptosis proteins (IAPS) antagonist 0
AT-406 (SM-406) Pharma 0
BV6 Pharma 0
SM-164 Pharma Anticancer agent 0

(12) Additional Compounds for BIRC3 Gene - From: Novoseek

Name Synonyms Role CAS Number PubChem IDs PubMed IDs

(5) ApexBio Compounds for BIRC3 Gene

Compound Action Cas Number
AT-406 (SM-406) 1071992-99-8
BV6 1001600-56-1
GDC-0152 IAP antagonist,potent amd samll-molecule 873652-48-3
LCL161 Antagonist of IAPs inhibitor 1005342-46-0
SM-164 Anticancer agent 957135-43-2
genes like me logo Genes that share compounds with BIRC3: view

Drug Products

Transcripts for BIRC3 Gene

Unigene Clusters for BIRC3 Gene

Baculoviral IAP repeat containing 3:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

  • Addgene plasmids for BIRC3

Alternative Splicing Database (ASD) splice patterns (SP) for BIRC3 Gene

ExUns: 1a · 1b ^ 2 ^ 3 ^ 4a · 4b · 4c ^ 5a · 5b · 5c ^ 6 ^ 7 ^ 8 ^ 9 ^ 10a · 10b ^ 11 ^ 12 ^ 13a · 13b
SP1: - - - -
SP2: -
SP3:
SP4:
SP5: -

Relevant External Links for BIRC3 Gene

GeneLoc Exon Structure for
BIRC3
ECgene alternative splicing isoforms for
BIRC3

Expression for BIRC3 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for BIRC3 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for BIRC3 Gene

This gene is overexpressed in Blymphocyte (33.1), Peripheral blood mononuclear cells (27.7), and CD4 Tcells (8.3).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for BIRC3 Gene



Protein tissue co-expression partners for BIRC3 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of BIRC3 Gene:

BIRC3

SOURCE GeneReport for Unigene cluster for BIRC3 Gene:

Hs.127799

mRNA Expression by UniProt/SwissProt for BIRC3 Gene:

Q13489-BIRC3_HUMAN
Tissue specificity: Highly expressed in fetal lung, and kidney. In the adult, expression is mainly seen in lymphoid tissues, including spleen, thymus and peripheral blood lymphocytes.

Evidence on tissue expression from TISSUES for BIRC3 Gene

  • Liver(4.4)
  • Intestine(2.8)
  • Stomach(2.7)
  • Lung(2.6)
  • Lymph node(2.6)
  • Spleen(2.4)
  • Blood(2.3)
  • Heart(2.1)

Phenotype-based relationships between genes and organs from Gene ORGANizer for BIRC3 Gene

Germ Layers:
  • ectoderm
  • endoderm
  • mesoderm
Systems:
  • digestive
  • integumentary
  • nervous
  • respiratory
Organs:
Head and neck:
  • brain
  • head
Thorax:
  • esophagus
  • lung
Abdomen:
  • intestine
  • large intestine
  • stomach
Pelvis:
  • rectum
General:
  • skin
  • sweat gland
genes like me logo Genes that share expression patterns with BIRC3: view

Primer Products

No data available for mRNA differential expression in normal tissues for BIRC3 Gene

Orthologs for BIRC3 Gene

This gene was present in the common ancestor of animals.

Orthologs for BIRC3 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia BIRC3 34 35
  • 99.12 (n)
cow
(Bos Taurus)
Mammalia BIRC3 34 35
  • 88.69 (n)
mouse
(Mus musculus)
Mammalia Birc3 34 16 35
  • 77.19 (n)
rat
(Rattus norvegicus)
Mammalia Birc3 34
  • 76.91 (n)
dog
(Canis familiaris)
Mammalia BIRC3 34 35
  • 76.43 (n)
oppossum
(Monodelphis domestica)
Mammalia -- 35
  • 74 (a)
ManyToMany
-- 35
  • 72 (a)
ManyToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 35
  • 73 (a)
OneToMany
chicken
(Gallus gallus)
Aves ITA 35
  • 70 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia -- 35
  • 67 (a)
OneToMany
zebrafish
(Danio rerio)
Actinopterygii birc2 35
  • 51 (a)
OneToMany
fruit fly
(Drosophila melanogaster)
Insecta Iap2 36 35
  • 28 (a)
th 35
  • 24 (a)
ManyToMany
sea squirt
(Ciona savignyi)
Ascidiacea -- 35
  • 55 (a)
ManyToMany
-- 35
  • 41 (a)
ManyToMany
-- 35
  • 40 (a)
ManyToMany
-- 35
  • 30 (a)
ManyToMany
-- 35
  • 29 (a)
ManyToMany
-- 35
  • 28 (a)
ManyToMany
-- 35
  • 26 (a)
ManyToMany
-- 35
  • 21 (a)
ManyToMany
Species where no ortholog for BIRC3 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for BIRC3 Gene

ENSEMBL:
Gene Tree for BIRC3 (if available)
TreeFam:
Gene Tree for BIRC3 (if available)

Paralogs for BIRC3 Gene

Paralogs for BIRC3 Gene

(19) SIMAP similar genes for BIRC3 Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with BIRC3: view

Variants for BIRC3 Gene

Sequence variations from dbSNP and Humsavar for BIRC3 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type
rs1000216597 -- 102,339,222(+) TTTTT(A/G)TCTAG utr-variant-3-prime
rs1000279607 -- 102,326,827(+) CTCGA(A/G)CCTCG intron-variant
rs1000310889 -- 102,331,821(+) TTTTT(A/C)GTAGA intron-variant
rs1000399584 -- 102,332,744(+) TATAG(C/G)ATCAT intron-variant
rs1000616550 -- 102,338,992(+) CCAAG(C/T)GAGGG utr-variant-3-prime

Structural Variations from Database of Genomic Variants (DGV) for BIRC3 Gene

Variant ID Type Subtype PubMed ID
dgv1269n100 CNV gain 25217958
nsv556141 CNV gain 21841781
nsv556142 CNV loss 21841781

Variation tolerance for BIRC3 Gene

Residual Variation Intolerance Score: 29.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.84; 34.49% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for BIRC3 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
BIRC3

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for BIRC3 Gene

Disorders for BIRC3 Gene

MalaCards: The human disease database

(10) MalaCards diseases for BIRC3 Gene - From: Orphanet, DISEASES, Novoseek, and GeneCards

Disorder Aliases PubMed IDs
lymphoma, malt, somatic
  • lymphoma, mucosa-associated lymphoid type
b-cell lymphoma of mucosa-associated lymphoid tissue
marginal zone b-cell lymphoma
  • marginal zone lymphoma
b-cell lymphomas
  • b-cell lymphoma
chronic neutrophilic leukemia
  • cnl
- elite association - COSMIC cancer census association via MalaCards
Search BIRC3 in MalaCards View complete list of genes associated with diseases

UniProtKB/Swiss-Prot

BIRC3_HUMAN
  • Note=A chromosomal aberration involving BIRC3 is recurrent in low-grade mucosa-associated lymphoid tissue (MALT lymphoma). Translocation t(11;18)(q21;q21) with MALT1. This translocation is found in approximately 50% of cytogenetically abnormal low-grade MALT lymphoma.

Relevant External Links for BIRC3

Genetic Association Database (GAD)
BIRC3
Human Genome Epidemiology (HuGE) Navigator
BIRC3
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
BIRC3
genes like me logo Genes that share disorders with BIRC3: view

No data available for Genatlas for BIRC3 Gene

Publications for BIRC3 Gene

  1. Structure of the MLT gene and molecular characterization of the genomic breakpoint junctions in the t(11;18)(q21;q21) of marginal zone B-cell lymphomas of MALT type. (PMID: 11066071) Baens M. … Marynen P. (Genes Chromosomes Cancer 2000) 3 4 22 64
  2. Suppression of apoptosis in mammalian cells by NAIP and a related family of IAP genes. (PMID: 8552191) Liston P. … Korneluk R.G. (Nature 1996) 2 3 4 64
  3. The TNFR2-TRAF signaling complex contains two novel proteins related to baculoviral inhibitor of apoptosis proteins. (PMID: 8548810) Rothe M. … Goeddel D.V. (Cell 1995) 2 3 4 64
  4. IKKI/-mediated tumorigenesis requires K63-linked polyubiquitination by a cIAP1/cIAP2/TRAF2 E3 ubiquitin ligase complex. (PMID: 23453969) Zhou A.Y. … Hahn W.C. (Cell Rep 2013) 3 4 64
  5. Inhibitor of apoptosis (IAP) proteins in regulation of inflammation and innate immunity. (PMID: 21447281) Damgaard R.B. … Gyrd-Hansen M. (Discov. Med. 2011) 3 4 64

Products for BIRC3 Gene

  • Addgene plasmids for BIRC3

Sources for BIRC3 Gene

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