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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

BIN3 Gene

protein-coding   GIFtS: 52
GCID: GC08M022477

Bridging Integrator 3

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Bridging Integrator 31 2

External Ids:    HGNC: 10541   Entrez Gene: 559092   Ensembl: ENSG000001474397   OMIM: 6063965   UniProtKB: Q9NQY03   

Export aliases for BIN3 gene to outside databases

Previous GC identifers: GC08P022082 GC08M022831 GC08M022298 GC08M022499 GC08M022533 GC08M021021


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for BIN3 Gene:
The product of this gene is a member of the BAR domain protein family. The encoded protein is comprised solely of
a BAR domain which is predicted to form coiled-coil structures and proposed to mediate dimerization, sense and
induce membrane curvature, and bind small GTPases. BAR domain proteins have been implicated in endocytosis,
intracellular transport, and a diverse set of other processes. (provided by RefSeq, Jul 2008)

GeneCards Summary for BIN3 Gene: 
BIN3 (bridging integrator 3) is a protein-coding gene. Diseases associated with BIN3 include ornithosis, and pancreatic cancer. GO annotations related to this gene include cytoskeletal adaptor activity and protein domain specific binding.

UniProtKB/Swiss-Prot: BIN3_HUMAN, Q9NQY0
Function: Involved in cytokinesis and septation where it has a role in the localization of F-actin

Gene Wiki entry for BIN3 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000008.10  NT_167187.1  NC_018919.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the BIN3 gene promoter:
         Nkx3-1   Nkx3-1 v4   AP-1   Nkx3-1 v1   Tal-1beta   LCR-F1   E47   Nkx3-1 v2   GATA-6   Nkx3-1 v3   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): BIN3 promoter sequence
   Search SABiosciences Chromatin IP Primers for BIN3

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat BIN3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 8p21.3   Ensembl cytogenetic band:  8p21.3   HGNC cytogenetic band: 8p21.2

BIN3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
BIN3 gene location

GeneLoc information about chromosome 8         GeneLoc Exon Structure

GeneLoc location for GC08M022477:  view genomic region     (about GC identifiers)

Start:
22,477,931 bp from pter      End:
22,526,661 bp from pter
Size:
48,731 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: BIN3_HUMAN, Q9NQY0 (See protein sequence)
Recommended Name: Bridging integrator 3  
Size: 253 amino acids; 29665 Da
Subcellular location: Cytoplasm, cytoskeleton
Sequence caution: Sequence=AAH01223.1; Type=Erroneous initiation;
Secondary accessions: Q9BVG2 Q9NVY9
Alternative splicing: 2 isoforms:  Q9NQY0-1   Q9NQY0-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for BIN3: NX_Q9NQY0

Explore proteomics data for BIN3 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9NQY0

  • BIN3 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    BIN3 Protein Expression
    REFSEQ proteins: NP_061158.1  
    ENSEMBL proteins: 
     ENSP00000276416   ENSP00000430423   ENSP00000382859   ENSP00000430546   ENSP00000429660  
     ENSP00000428768  

    Human Recombinant Protein Products for BIN3: 
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    OriGene Protein Over-expression Lysate for BIN3
    OriGene MassSpec for BIN3 
    OriGene Custom Protein Services for BIN3
    GenScript Custom Purified and Recombinant Proteins Services for BIN3
    Novus Biologicals BIN3 Proteins
    Novus Biologicals BIN3 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for BIN3 

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm IEA--
    GO:0005856cytoskeleton IEA--

    BIN3 for ontologies           About GeneDecksing



    BIN3 Antibody Products: 
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    Cloud-Clone Corp. Antibodies for BIN3 
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    Assay Products for BIN3: 
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    Cloud-Clone Corp. ELISAs for BIN3 
    Cloud-Clone Corp. CLIAs for BIN3


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    2 InterPro protein domains:
     IPR027267 AH/BAR-dom
     IPR004148 BAR_dom

    Graphical View of Domain Structure for InterPro Entry Q9NQY0

    ProtoNet protein and cluster: Q9NQY0

    UniProtKB/Swiss-Prot: BIN3_HUMAN, Q9NQY0
    Similarity: Contains 1 BAR domain


    BIN3 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: BIN3_HUMAN, Q9NQY0
    Function: Involved in cytokinesis and septation where it has a role in the localization of F-actin

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI18654987
    GO:0008093cytoskeletal adaptor activity NAS11274158
         
    BIN3 for ontologies           About GeneDecksing


    Phenotypes:
         3 GenomeRNAi human phenotypes for BIN3:
     Decreased Hepatitis C virus re  G0/1 arrest  Increased G1 DNA content 

         6 MGI mutant phenotypes (inferred from 1 allele(MGI details for Bin3):
     hematopoietic system  immune system  liver/biliary system  respiratory system  tumorigenesis 
     vision/eye 

    BIN3 for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Bin3tm1Gcp for BIN3

       inGenious Targeting Laboratory - Custom generated mouse model solutions for BIN3 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for BIN3

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for BIN3 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for BIN3 

    miRNA
    Products:
        
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat BIN3
    8/16 QIAGEN miScript miRNA Assays for microRNAs that regulate BIN3 (see all 16):
    hsa-miR-3163 hsa-miR-98 hsa-miR-495 hsa-let-7d hsa-let-7c hsa-miR-4282 hsa-let-7i hsa-miR-184
    SwitchGear 3'UTR luciferase reporter plasmidBIN3 3' UTR sequence
    Inhib. RNA
    Products:
        
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    Gene Editing
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    Sirion Biotech Customized adenovirus for overexpression of BIN3

    Clone
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    Sino Biological Human cDNA Clone for BIN3
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                         Customized lentivirus expression plasmids for stable overexpression of BIN3 

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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for BIN3


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section




    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for BIN3

    STRING Interaction Network Preview (showing 5 interactants - click image to see 22)

    5/23 Interacting proteins for BIN3 (Q9NQY01, 3 ENSP000002764164) via UniProtKB, MINT, STRING, and/or I2D (see all 23)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    DNMBPQ6XZF71, 3, ENSP000003156594EBI-2653038,EBI-2483419 I2D: score=1 STRING: ENSP00000315659
    ERHP840903I2D: score=1 
    DPH3ENSP000004195994STRING: ENSP00000419599
    VBP1ENSP000002864284STRING: ENSP00000286428
    PFDN4ENSP000003604734STRING: ENSP00000360473
    About this table

    Gene Ontology (GO): 5 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000910cytokinesis NAS11274158
    GO:0000917barrier septum assembly IEA--
    GO:0007015actin filament organization NAS11274158
    GO:0008104protein localization IMP11274158
    GO:0009826unidimensional cell growth IMP11274158

    BIN3 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for BIN3

    Search CenterWatch for drugs/clinical trials and news about BIN3

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for BIN3 gene: 
    NM_018688.4  

    Unigene Cluster for BIN3:

    Bridging integrator 3
    Hs.433722  [show with all ESTs]
    Unigene Representative Sequence: BC050314
    11 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000276416(uc003xcl.3 uc010ltw.3) ENST00000520489 ENST00000519513
    ENST00000399977 ENST00000519335 ENST00000519863 ENST00000522687 ENST00000520292
    ENST00000521140 ENST00000518366 ENST00000522268
    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat BIN3
    8/16 QIAGEN miScript miRNA Assays for microRNAs that regulate BIN3 (see all 16):
    hsa-miR-3163 hsa-miR-98 hsa-miR-495 hsa-let-7d hsa-let-7c hsa-miR-4282 hsa-let-7i hsa-miR-184
    SwitchGear 3'UTR luciferase reporter plasmidBIN3 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
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    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat BIN3
    Clone
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    OriGene clones in human, mouse for BIN3 (see all 7)
    OriGene ORF clones in mouse, rat for BIN3
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    GenScript: all cDNA clones in your preferred vector: BIN3 (NM_018688)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for BIN3
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat BIN3
    Sirion Biotech Customized lentivirus for stable overexpression of BIN3 
                         Customized lentivirus expression plasmids for stable overexpression of BIN3 
    Primer
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    OriGene qPCR primer pairs and template standards for BIN3
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat BIN3
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat BIN3

    Additional mRNA sequence: 

    AF271732.1 AK001289.1 AK023980.1 AK124486.1 AK222470.1 BC001223.1 BC009824.2 BC050314.1 

    17 DOTS entries:

    DT.454185  DT.91738811  DT.100848059  DT.307907  DT.100028655  DT.40114938  DT.121471422  DT.121471418 
    DT.91969078  DT.92016419  DT.95104538  DT.95137166  DT.97800537  DT.97845467  DT.100867432  DT.121471393 
    DT.95257484 

    24/278 AceView cDNA sequences (see all 278):

    CR591250 AI961825 CD244345 CB528956 BQ888721 BQ938840 BU634482 AI417058 
    CR612252 BQ953290 AA744592 AK124486 AK023980 BC001223 BE796954 AI276477 
    CR620938 AI917084 BM551488 BE550579 CB852760 CR596305 AK001289 BQ016153 

    GeneLoc Exon Structure

    5/10 Alternative Splicing Database (ASD) splice patterns (SP) for BIN3 (see all 10)    About this scheme

    ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3a · 3b ^ 4 ^ 5 ^ 6 ^ 7a · 7b ^ 8 ^ 9a · 9b · 9c ^ 10 ^ 11a · 11b ^ 12a · 12b · 12c · 12d
    SP1:                                      -           -                 -     -                                                               
    SP2:                                      -           -                 -     -                             -     -                           
    SP3:                                      -           -                 -     -                                                               
    SP4:                                      -     -     -                 -     -                             -     -                           
    SP5:                                      -                             -     -                                                               


    ECgene alternative splicing isoforms for BIN3

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    BIN3 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CGTTGTGGGC
    BIN3 Expression
    About this image


    See BIN3 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for BIN3

    SOURCE GeneReport for Unigene cluster: Hs.433722

    UniProtKB/Swiss-Prot: BIN3_HUMAN, Q9NQY0
    Tissue specificity: Ubiquitously expressed except in brain

        SABiosciences Custom PCR Arrays for BIN3
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for BIN3

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals and fungi.

    Orthologs for BIN3 gene from 5/16 species (see all 16)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Bin31 , 5 bridging integrator 31, 5 87.88(n)1
    94.47(a)1
      14 (36.21 cM)5
    577841  NM_021328.31  NP_067303.11 
     701001455 
    lizard
    (Anolis carolinensis)
    Reptilia BIN36
    Uncharacterized protein
    86(a)
    1 ↔ 1
    GL343443.1(591835-647059)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia Str.99142 Transcribed sequence with moderate similarity to protein more 75.9(n)    CF378560.1 
    zebrafish
    (Danio rerio)
    Actinopterygii zgc:1584151 zgc:158415 76.55(n)
    81.82(a)
      323976  NM_001123044.1  NP_001116516.1 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes RVS161(YCR009C)4
    RVS1611
    Amphiphysin-like lipid raft protein; interacts with more4
    Rvs161p1
    40.86(n)1
    28.63(a)1
      3(131542-130745)4
    8503671, 4  NP_009935.11, 4 


    ENSEMBL Gene Tree for BIN3 (if available)
    TreeFam Gene Tree for BIN3 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for BIN3 gene
    1 SIMAP similar gene for BIN3 using alignment to 6 protein entries:     BIN3_HUMAN (see all proteins):
    FLJ00367

    BIN3 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/1143 SNPs in BIN3 are shown (see all 1143)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 8 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs774510211,2
    F--22478489(+) GTTCAG/TGGCCT 1 -- ut311Minor allele frequency- T:0.01WA 118
    rs1412498141,2
    C--22478545(+) AGAGGG/TCTCCC 1 -- ut310--------
    rs1449621941,2
    --22478590(+) ACAACA/GCATGC 1 -- ut310--------
    rs70009931,2
    C,F--22478591(+) CAACGC/TATGCA 1 -- ut31 ese31Minor allele frequency- T:0.08WA 118
    rs70084291,2
    C,F,A--22478592(+) AACGCA/GTGCAA 1 -- ut31 ese37Minor allele frequency- G:0.18NA WA EA 382
    rs1380987241,2
    C--22478663(+) AGGCCA/GTGGGC 1 -- ut310--------
    rs70010411,2
    C,F--22478685(+) CTGGAC/TGGTTC 1 -- ut31 ese34Minor allele frequency- T:0.03NA WA 260
    rs2020372711,2
    --22478792(+) CTCAG-/GAAGAGTC 1 -- cds10--------
    rs1839287891,2
    --22478816(+) AGGGCC/TGGCAA 1 -- ut310--------
    rs1147382441,2
    C,F--22478817(+) GGGCCG/AGCAAG 1 -- ut311Minor allele frequency- A:0.01WA 118

    HapMap Linkage Disequilibrium report for BIN3 (22477931 - 22526661 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 5 variations for BIN3:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv1939469CNV Deletion18987734
    esv1623916CNV Insertion17803354
    nsv890673CNV Loss21882294
    essv21913CNV CNV17122850
    essv19243CNV CNV17122850

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing BIN3
    DNA2.0 Custom Variant and Variant Library Synthesis for BIN3

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 606396    OMIM disorders: --

    3 diseases for BIN3:    About MalaCards
    ornithosis    pancreatic cancer    pancreatitis

    1 disease from the University of Copenhagen DISEASES database for BIN3:
    Ornithosis

    BIN3 for disorders           About GeneDecksing

    Genetic Association Database (GAD): BIN3

    Export disorders for BIN3 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for BIN3 gene, integrated from 9 sources (see all 14):
    (articles sorted by number of sources associating them with BIN3)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Human BIN3 complements the F-actin localization defects caused by loss of Hob3p, the fission yeast homolog of Rvs161p. (PubMed id 11274158)1, 2, 9 Routhier E.L....Prendergast G.C. (2001)
    2. The BAR domain proteins: molding membranes in fission, fusion, and phagy. (PubMed id 16524918)1, 3 Ren G....Munn A.L. (2006)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    5. Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
    6. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
    7. Identification of multi-SH3 domain-containing protein interactome in pancreatic cancer: a yeast two-hybrid approach. (PubMed id 18654987)1 Thalappilly S....Dusetti N.J. (2008)
    8. A quantitative atlas of mitotic phosphorylation. (PubMed id 18669648)2 Dephoure N.... Gygi S.P. (2008)
    9. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965)1 Lamesch P.... Vidal M. (2007)
    10. Large-scale mapping of human protein-protein interactions by mass spectrometry. (PubMed id 17353931)1 Ewing R.M.... Figeys D. (2007)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 55909 HGNC: 1054 AceView: BIN3 Ensembl:ENSG00000147439 euGenes: HUgn55909
    ECgene: BIN3 H-InvDB: BIN3

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for BIN3 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for BIN3 gene:
    Search GeneIP for patents involving BIN3

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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