BIN2 Gene
protein-coding GIFtS: 48
GCID: GC12M051697
|
|
bridging integrator 2
| |
Aliases
for BIN2 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Bridging Integrator 21 2 | | BRAP-11 2 | | Breast Cancer-Associated Protein 12 3 | | Breast Cancer Associated Protein BRAP12 | | Bridging Integrator-22 | | BRAP13 |
Export aliases for BIN2 gene to outside databasesPrevious GC identifers: GC12M051831 GC12M051391 GC12M049961 GC12M048707 |
Summaries
for BIN2 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
UniProtKB/Swiss-Prot: BIN2_HUMAN, Q9UBW5Function: Promotes cell motility and migration, probably via its interaction with the cell membrane and with podosomeproteins that mediate interaction with the cytoskeleton. Modulates membrane curvature and mediates membranetubulation. Plays a role in podosome formation. Inhibits phagocytosis
|
Genomic Views
for BIN2 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000012.11 NC_018923.1 NT_029419.12
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the BIN2 gene promoter:
c-Fos AP-1 AML1a Tal-1 HNF-4alpha2 HNF-4alpha1 E47 c-Jun
Other transcription factors
Search SABiosciences Chromatin IP Primers for BIN2
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat BIN2 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 12q13 Ensembl cytogenetic band: 12q13.13 HGNC cytogenetic band: 12q13.13BIN2 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 12 GeneLoc Exon Structure GeneLoc location for GC12M051697: view genomic region
(about GC identifiers)
Start:
|
51,674,822 bp from pter |
End:
|
51,718,452 bp from pter |
Size:
|
43,631 bases |
Orientation:
|
minus strand |
|
Proteins
for BIN2 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: BIN2_HUMAN, Q9UBW5 (See
protein sequence)Recommended Name: Bridging integrator 2 Size: 565 amino acids; 61874 Da
Subunit: Homodimer. Interacts with BIN1. Interacts with ARHGEF6 (via SH3 domain), ARHGEF7 (via SH3 domain), SH3GL1,SH3GL2 and SH3GL3. Identified in a complex with ARHGEF6 and GIT2
Subcellular location: Cytoplasm. Cell projection, podosome membrane; Peripheral membrane protein; Cytoplasmic side.Cytoplasm, cell cortex. Cell projection, phagocytic cup. Note=Associates with membranes enriched in phosphoinositides.Detected in the actin-rich cell cortex at the leading edge of migrating cells. Detected at podosomes, at an actin-richring-like structure
Sequence caution: Sequence=BAA91376.1; Type=Erroneous initiation; Note=Translation N-terminally extended;Sequence=BAA91376.1; Type=Frameshift; Positions=156;
2 PDB 3D structures from  and Proteopedia  for BIN2:4AVM (3D)
4I1Q (3D)
Secondary accessions: Q86VV0 Q9NWK4 Q9UKN4Alternative splicing: 2 isoforms: Q9UBW5-1 Q9UBW5-2 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for BIN2: NX_Q9UBW5
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9UBW5
BIN2 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_057377.2
ENSEMBL proteins: ENSP00000445874 ENSP00000410217 ENSP00000267012
Human Recombinant Protein Products:
Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table
BIN2 for ontologies About GeneDecksing
BIN2 Antibody Products:
Assay Products for BIN2: |
Protein
Domains /
Families
for BIN2 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
BIN2 for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q9UBW5ProtoNet protein and cluster: Q9UBW5 UniProtKB/Swiss-Prot: BIN2_HUMAN, Q9UBW5Domain: The BAR domain mediates dimerization and interaction with membranes enriched in phosphatidylinositidesSimilarity: Contains 1 BAR domain |
Function
for BIN2 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: BIN2_HUMAN, Q9UBW5Function: Promotes cell motility and migration, probably via its interaction with the cell membrane and with podosomeproteins that mediate interaction with the cytoskeleton. Modulates membrane curvature and mediates membranetubulation. Plays a role in podosome formation. Inhibits phagocytosisInduction: Up-regulated during monocytic differentiation
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for BIN2 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for BIN2
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: BIN2 (NM_016293) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for BIN2 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat BIN2 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for BIN2 |
Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table
BIN2 for ontologies About GeneDecksing
|
Pathways & Interactions
for BIN2 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for BIN2
STRING Interaction
Network Preview (showing 4 interactants - click image to see more details)
4 Interacting proteins for BIN2 (Q9UBW51, 3 ENSP000002670124) via UniProtKB, MINT, STRING, and/or I2DAbout this table
Gene Ontology (GO): 4 biological process terms (GO ID links to tree view): About this table
BIN2 for ontologies About GeneDecksing
|
Drugs & Compounds
for BIN2 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for BIN2
Search CenterWatch for drugs/clinical trials and news about BIN2
|
Transcripts
for BIN2 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for BIN2 gene: NM_016293.2 Unigene Cluster for BIN2: Bridging integrator 2 Hs.14770 [show with all ESTs]Unigene Representative Sequence: AK2259113 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000544402 ENST00000452142(uc009zlz.3) ENST00000267012(uc001ryg.3 uc001ryh.3 uc010sng.2)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for BIN2 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for BIN2
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: BIN2 (NM_016293) | | | DNA2.0 Custom Codon Optimized Gene
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Additional cDNA sequence: AB032698.1 AF146531.1 AK000783.1 AK093638.1 AK225911.1 AK300211.1 AK314304.1 BC047686.1 8 DOTS entries: DT.213694 DT.92423269 DT.40123682 DT.95147399 DT.95265026 DT.100712927 DT.91647061 DT.92423270 24/120 AceView cDNA sequences (see all 120): AW768285 AI052200 BE466294 BG388638 BU753979 AW118269 NM_016293 AI247125 AW440832 AA678263 BQ018830 BX281612 AA776278 AA988660 AA743030 AK093638 CD109693 CD696710 BX372325 BM682716 BU617394 AI476354 AA468710 AA987798
GeneLoc Exon Structure
5 Alternative Splicing Database (ASD) splice patterns (SP) for BIN2 About this scheme
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11a | · | 11b | ^ | 12 | ^ | 13 | ^ | 14 |
|---|
|
| SP1: | | | | | | | | | - | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | - | | | | | | | | - | | - | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for BIN2
|
Expression
for BIN2 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| BIN2 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GTACCAGAAA
About this image
See BIN2 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for BIN2
SOURCE GeneReport for Unigene cluster: Hs.14770
UniProtKB/Swiss-Prot: BIN2_HUMAN, Q9UBW5Tissue specificity: Detected in natural killer cells (at protein level). Highest level expression seen in spleen andperipheral blood leukocytes and is also expressed at high levels in thymus, colon and placenta, suggestingpreferential expression in hematopoietic tissues
SABiosciences Custom PCR Arrays for BIN2
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for BIN2
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat BIN2 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat BIN2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat BIN2 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for BIN2 |
Orthologs
for BIN2 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for BIN2 gene from 6/16 species (see all 16) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
mouse
(Mus musculus) |
Mammalia |
Bin25 |
bridging integrator 2 |
-- |
|
15 (56.37 cM) - |
chicken
(Gallus gallus) |
Aves |
BIN21 |
bridging integrator 2 |
58.65(n)
55.85(a) |
|
777552 NM_001080896.1 NP_001074365.1 |
lizard
(Anolis carolinensis) |
Reptilia |
BIN26 |
-- |
73(a) |
1 ↔ 1 |
2(67629274-67691641) |
zebrafish
(Danio rerio) |
Actinopterygii |
BC044473.12 |
-- |
75.33(n) |
|
327387 BC044473.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
Amph3 |
NOT synaptic vesicle endocytosis |
36(a) |
|
-- |
worm
(Caenorhabditis elegans) |
Secernentea |
F58G6.13 |
amphiphysin like |
38(a) |
|
IV(9644867-9647871) -- |
ENSEMBL Gene Tree for BIN2 (if available)
TreeFam Gene Tree for BIN2 (if available) |
Paralogs
for BIN2 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for BIN2 gene
- BIN12 AMPH2
2 SIMAP similar genes for BIN2 using alignment to 2 protein entries: BIN2_HUMAN (see all proteins):BIN1 AMPH
BIN2 for paralogs About GeneDecksing
3 Pseudogenes.org Pseudogenes for BIN2
PGOHUM00000245980 PGOHUM00000235280 PGOHUM00000235657
|
Genomic Variants
for BIN2 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 12 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for BIN2 (51674822 - 51718452 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for BIN2: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing BIN2 |
|
Disorders
/ Diseases
for BIN2 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
BIN2 for disorders About GeneDecksing
OMIM gene information: 605936
OMIM disorders: --
6  diseases for BIN2: About MalaCardsepididymo-orchitis breast cancer tricuspid valve insufficiency orbital cellulitis
orchitis cellulitis
1 disease from the University of Copenhagen DISEASES database for BIN2:epididymo-orchitis Human Genome Epidemiology (HuGE) Navigator: BIN2 (1 document)
Export disorders for BIN2 gene to outside databases
|
Publications
for BIN2 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for BIN2 gene, integrated from 9 sources (see all 13):
(articles sorted by number of sources associating them with BIN2) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Bin2, a functionally nonredundant member of the BAR adaptor gene family. (PubMed id 10903846)1, 2, 3 Ge K. and Prendergast G.C. (2000)
- The finished DNA sequence of human chromosome 12. (PubMed id 16541075)1, 2 Scherer S.E.... Gibbs R.A. (2006)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Bin2 is a membrane sculpting N-BAR protein that influences leucocyte podosomes, motility and phagocytosis. (PubMed id 23285027)2 Sanchez-Barrena M.J.... McMahon H.T. (2012)
- A genome-wide association study of aging. (PubMed id 21782286)1 Walter S....Franceschini N. (2011)
- A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
- Genome-wide YFP fluorescence complementation screen id entifies new regulators for telomere signaling in human cells. (PubMed id 21044950)1 Lee O.H....Songyang Z. (2011)
- Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1 Rose J.E....Uhl G.R. (2010)
- Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. (PubMed id 19690332)2 Mayya V.... Han D.K. (2009)
|
External Searches for BIN2 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing BIN2 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing BIN2 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing BIN2 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for BIN2 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for BIN2 gene:
Search GeneIP for patents involving BIN2
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for BIN2 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for BIN2 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for BIN2 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for BIN2 | | | OriGene Protein Over-expression Lysate for BIN2 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for BIN2 | | OriGene 3'-UTR Clone for BIN2 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for BIN2 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for BIN2 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for BIN2 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat BIN2 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing BIN2 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat BIN2 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat BIN2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat BIN2 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat BIN2 |
| |
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| |  |  |  |  | | | | |
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 |
 |
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| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for BIN2 |
|  |  |  | | | | ThermoFisher Antibody for BIN2 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat BIN2 |
|
|
|
|
