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BIK Gene

protein-coding GIFtS: 63

GC22P041831

BCL2-interacting killer (apoptosis-inducing)
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

Aliases
BIP1 ^², ³
BP4 ^², ³
NBK ^¹, ², ³, ⁵
OTTHUMP00000028974 ^²

Descriptions
Apoptosis inducer NBK ^³
BCL2-interacting killer ^²
BCL2-interacting killer (apoptosis-inducing) ^²
apoptosis-inducing NBK ^²

External Ids
HGNC: 1051¹
Entrez Gene: 638²
UniProtKB: Q13323³
Ensembl: ENSG00000100290⁷

Search outside databases for aliases for BIK gene

Previous GC identifers: GC22P040109 GC22P041737

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

EntrezGene summary for BIK:

The protein encoded by this gene is known to interact with cellular and viral survival-promoting

proteins, such as BCL2 and the Epstein-Barr virus in order to enhance programed cell death.

Because its activity is suppressed in the presence of survival-promoting proteins, this protein is

suggested as a likely target for antiapoptotic proteins. This protein shares a critical BH3 domain

with other death-promoting proteins, BAX and BAK. [provided by RefSeq]

UniProtKB/Swiss-Prot: BIK_HUMAN, Q13323

Function: Accelerates programmed cell death. Binding to the apoptosis repressors Bcl-X(L), BHRF1,

Bcl-2 or its adenovirus homolog E1B 19k protein suppresses this death-promoting activity. Does not

interact with BAX

Gene Wiki entry for BIK (Bcl-2-interacting_killer)

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the BIK gene

Entrez Gene cytogenetic band: 22q13.31 Ensembl cytogenetic band: 22q13.2 HGNC chromosome: 22

BIK Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 22 GeneLoc Exon Structure

GeneLoc location for GC22P041831: (about GC identifiers)

Start:	41,836,701 bp from pter
End:	41,855,662 bp from pter
Size:	18,962 bases
Orientation:	plus strand

RefSeq DNA sequence:

NC_000022.9 NT_011520.11

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
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UniProtKB/Swiss-Prot: BIK_HUMAN, Q13323 (See protein sequence)

Recommended Name: Bcl-2-interacting killer

Size: 160 amino acids; 18016 Da

Subcellular location: Endomembrane system; Single-pass membrane protein. Note=Around the nuclear

envelope, and in cytoplasmic membranes

PDB structures from and Proteopedia :

2IPE (3D)

Secondary accessions: Q16582

Post-translational modifications:

View phosphorylation sites using PhosphoSite²

REFSEQ proteins: NP_001188.1

ENSEMBL proteins:

ENSP00000216115

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
	Browse Human Recombinant Proteins at Sigma-Aldrich
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (Bik)
	Human Recombinant Proteins from Abnova (BIK)

Browse Origene for full length recombinant human proteins expressed in human HEK293 cells

4 Gene Ontology (GO) cellular component terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005740	mitochondrial envelope	IEA	--
GO:0012505	endomembrane system	IEA	--
GO:0016020	membrane	IEA	--
GO:0016021	integral to membrane	IEA	--

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Antibodies for BIK:

	Browse Antibodies Central at Invitrogen
	Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Sigma-Aldrich Antibodies for BIK
	Browse R&D Systems for Antibodies
	Antibodies from Abcam (Bik), each with their Abpromise^SM
	Monoclonal and Polyclonal Antibodies from Abnova (BIK)
	Novus Biologicals Antibodies for BIK

Assays for BIK:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

Graphical View of Domain Structure for InterPro Entry Q13323

ProtoNet protein and cluster: Q13323

1 Blocks protein family: IPB000712 Apoptosis regulator Bcl-2 protein

UniProtKB/Swiss-Prot: BIK_HUMAN, Q13323

Domain: Intact BH3 motif is required by BIK, BID, BAK, BAD and BAX for their pro-apoptotic activity

and for their interaction with anti-apoptotic members of the Bcl-2 family

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
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Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (BIK)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (BIK)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_001197

Applied Biosystems Silencer® siRNAs for BIK

Sigma-Aldrich siRNA and siRNA Panels for BIK

Sigma-Aldrich shRNA Panels and shRNA for BIK

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Invitrogen Clones for BIK
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clone in CMV expression vector: NM_001197
Myc/DDK tagged cDNA clone in CMV expression vector: NM_001197
untagged cDNA clone in CMV expression vector: NM_001197

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_001197

UniProtKB/Swiss-Prot: BIK_HUMAN, Q13323

Function: Accelerates programmed cell death. Binding to the apoptosis repressors Bcl-X(L), BHRF1,

Bcl-2 or its adenovirus homolog E1B 19k protein suppresses this death-promoting activity. Does not

interact with BAX

Genatlas biochemistry entry for BIK:

BCL2-interacting killer (apoptosis-inducing)

8 MGI mutant phenotypes (inferred from 2 alleles) (MGI details for Bik):

endocrine/exocrine gland	growth/size	hematopoietic system	immune system	life span-post-weaning/aging
normal	renal/urinary system	reproductive system

1 Gene Ontology (GO) molecular function term (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005515	protein binding	IPI	15694340 16697956

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
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1 Sigma-Aldrich "Your Favorite Gene" Pathway for BIK (Your Favorite Gene powered by Ingenuity)

Docosahexaenoic Acid (DHA) Signaling

GeneDecks BIK for the pathways selected above

About GeneDecksing

Gene Network Central^TM Interacting Genes and Proteins Network for BIK

5/18 Interacting proteins for BIK (Q13323^{1, 2} ENSP00000216115³) via UniProtKB, MINT, and/or STRING (see all 18 )

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
BCL2	P10415¹, ENSP00000329623³	EBI-700794, EBI-77694 STRING (score=.999)
BCL2L1	Q07817¹, ENSP00000365230³	EBI-700794, EBI-78035 STRING (score=.999)
MCL1	Q07820¹, ENSP00000358022³	EBI-700794, EBI-1003422 STRING (score=.97)
BCL2L2	Q92843¹, ENSP00000250405³	EBI-700794, EBI-707714 STRING (score=.902)
Bcl2a1 Bcl2a1 (xeno)	Q07440¹	EBI-700794, EBI-707754

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2 Gene Ontology (GO) biological process terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006917	induction of apoptosis	TAS	10381623
GO:0042981	regulation of apoptosis	IEA	--

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(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Compounds for BIK available from Tocris Bioscience
1 Novoseek chemical compound relationship for BIK gene

Compound	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
sp 600125	46.01	1	16082182 (1)

About this table

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (BIK)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (BIK)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_001197

Sigma-Aldrich siRNA and siRNA Panels for BIK

Sigma-Aldrich shRNA Panels and shRNA for BIK

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_001197

REFSEQ mRNAs for BIK gene:

NM_001197.3

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_001197

              OriGene GFP tagged cDNA clone in CMV expression vector: NM_001197
                                 Myc/DDK tagged cDNA clone in CMV expression vector: NM_001197
                                 untagged cDNA clone in CMV expression vector: NM_001197

Additional cDNA sequence:

BC001599.1 BT006728.1 CR456390.1 CR541863.1 CR541883.1 U34584.1 U49730.1

2 DOTS entries:

DT.311800 DT.120646528

24/47 AceView cDNA sequences (see all 47 ):

AI620444 BM765910 AW510740 BM982248 BC001599 BX107823 NM_001197 BG057298

AI347538 BE269083 AI797545 AA731232 AA291322 BF514281 BG697020 AA835642

AI684897 BF063173 BF064055 AI798122 AI478735 AI659037 U34584 U49730

highest scoring ESTs for BIK:

U34584 AA291322 AA291323 AA576942 AA642457 AA689434 AA731232 AA731234 AA835642 AA947102

Unigene Cluster for BIK:

BCL2-interacting killer (apoptosis-inducing)

Hs.475055 [show with all ESTs]

Unigene Representative Sequence: BE561321

GeneLoc Exon Structure

1 Ensembl transcript including schematic representation:

ENST00000216115

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

BIK expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for BIK

¹ / ² / ³

3 probe-sets matching BIK gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
2011_s_at²^{, 3}	U95-A	1	1.00	1.00	1.00	1.00	U34584	1.00	1.00	1.00	1
205780_at²^{, 3}	U133-A	1	0.82	1.00	--	--	NM_001197	0.60	1.00	0.82	1
205780_at²	U133Plus2	1	0.82	1.00	--	--	--	--	--	--	--

GeneDecks BIK for binary patterns associated with the probe-sets selected above

About GeneDecksing

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Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: ATGCCTTTTT

SOURCE GeneReport for Unigene cluster: Hs.475055
Expression variation in blood from EXPOLDB for BIK

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for BIK gene from 3 species

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
chimpanzee (Pan troglodytes)	BIK¹	--	BCL2-interacting killer (apoptosis-inducing)	98.92(n) 98.71(a)	470232 XM_525617.2 XP_525617.2
rat (Rattus norvegicus)	Bik¹	--	BCL2-interacting killer (apoptosis-inducing)	64.02(n) 49.01(a)	114496 NM_053704.1 NP_446156.1
mouse (Mus musculus)	Bik^{1, 5}	15⁵	BCL2-interacting killer^{1, 5}	61.33(n)¹ 43.33(a)¹	12124¹ NM_007546.2¹ NP_031572.1¹ AF048838⁵ AK144937⁵ (see all 8)

About this table Species with no ortholog for BIK

ENSEMBL Gene Tree for BIK

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/211 NCBI SNPs in BIK are shown (see all 211 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 96)

AB	SNP ID	Valid	Chr 22 pos	Sequence	Recs	AA Chg	Type	More	Recs	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--			--
	rs926328^1,2	A,C,F,H	41836209(+)	`GGCTTA/TAAAAC`	1	--	ng5¹		20	EA NS MN EU WA	1896
	rs4988366^1,2	A,C,F,H	41835639(+)	`TTCACA/GGATGA`	1	--	ng5¹		12	NS EU EA WA NA	1290
--	rs4988361^1,2	C,F,H	41835016(+)	`ACCCCG/ATGTCA`	1	--	ng5¹		5	NS EU EA WA	592
--	rs4988364^1,2	A,C,F	41835388(+)	`tgaggC/Agggag`	1	--	ng5¹		2	NS NA	220
	rs4988360^1,2	C,F,H	41835015(+)	`GACCCC/TGTGTC`	1	--	ng5¹		12	NS NA EU EA WA	1298
	rs4988443^1,2	C,F,H	41855596(+)	`GCCCTC/TGGCAA`	1	--	ut3¹		9	NS NA EU EA WA	900
--	rs4988374^1,2	A,C,F	41836697(+)	`CGGGCC/AGCAGA`	1	--	ng5¹		1	NS	126
	rs4988362^1,2	C,F,H	41835101(+)	`TCCCTA/GCTCCT`	1	--	ng5¹		11	NS NA EA WA	1178
	rs11090141^1,2	F,H	41834934(+)	`CCTACA/TTACCT`	1	--	ng5¹		5	NA EU EA WA	458
	rs11090143^1,2	C,H	41850049(+)	`CCCGAC/TCATGG`	1	T/I	mis¹ ese³		10	NA EU EA WA	916

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HapMap Linkage Disequilibrium images for BIK (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 603392

8 Novoseek disease relationships for BIK gene

Disease	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
cancer	23.62	9	14633680 (2), 17027756 (2), 12467227 (1), 17064661 (1) (see all 6)
lymphoma b-cell	18.49	4	12874789 (3)
breast cancer	17.30	13	14983013 (3), 17440086 (3), 17047080 (3), 11782349 (1)
tumors	7.59	13	16060964 (3), 12467227 (2), 14633680 (2), 12696008 (1) (see all 7)
ovarian cancer	3.83	2	15498571 (2)
lymphoma	2.52	2	12874789 (1)
necrosis	0.00	1	12696008 (1)
metastasis	0.00	3	17194181 (1), 14633680 (1)

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Human Genome Epidemiology Navigator: BIK (6 documents)

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
About This Section

10/83 PubMed articles for BIK gene (see all 83 ):

Bik, a novel death-inducing protein shares a distinct sequence motif with Bcl-2 family proteins and interacts with viral and cellular survival-promoting proteins. (PubMed id 7478623)^{1, 2, 3, 4} Boyd J.M....Chinnadurai G. (1995)
The DNA sequence of human chromosome 22. (PubMed id 10591208)^{2, 3, 4} Dunham I....O'Brien K.P. (1999)
Induction of apoptosis by human Nbk/Bik, a BH3-containing protein that interacts with E1B 19K. (PubMed id 8816500)^{1, 3, 4} Han J.... White E. (1996)
A genome annotation-driven approach to cloning the human ORFeome. (PubMed id 15461802)^{3, 4} Collins J.E.... Dunham I. (2004)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{3, 4} Gerhard D.S....Malek J. (2004)
Mapping of a target region of allelic loss to a 0.5-cM interval on chromosome 22q13 in human colorectal cancer. (PubMed id 10500065)^{3, 4} Castells A.... Rustgi A.K. (1999)
A conserved domain in Bak, distinct from BH1 and BH2, mediates cell death and protein binding functions. (PubMed id 8521816)^{3, 4} Chittenden T.... Lutz R.J. (1995)
Regulation of expression of BIK proapoptotic protein in human breast cancer cells: p53-dependent induction of BIK mRNA by fulvestrant and proteasomal degradation of BIK protein. (PubMed id 17047080)^{1, 3} Hur J....Shioda T. (2006)
Involvement of Bik, a proapoptotic member of the Bcl-2 family, in surface IgM-mediated B cell apoptosis. (PubMed id 11342619)^{1, 3} Jiang A. and Clark E.A. (2001)
Transcriptional activation of the proapoptotic bik gene by E2F proteins in cancer cells. (PubMed id 17027756)^{1, 3} Real P.J....Fernandez-Luna J.L. (2006)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
About This Section

Entrez Gene: 638	HGNC: 1051	AceView: BIK	Ensembl:ENSG00000100290	euGenes: HUgn638
ECgene: BIK	H-InvDB: BIK

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
ATLAS Chromosomes in Cancer entry for BIK	Genetics and Cytogenetics in Oncology and Haematology
NIEHS-SNPs	http://egp.gs.washington.edu/data/bik/

Licensable Technologies for BIK
(Available from WIS Yeda, Salk, Tufts)

About This Section

(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
About This Section

Products for BIK:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for BIK-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for BIK		Antibodies for BIK
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for BIK		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

	Antibodies		Primer Pairs
	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
	Cell Selection/Detection Kits & Reagents		ELISA/Assay Development Kits & Reagents
	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
	Recombinant & Natural Proteins

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Tocris compounds for BIK

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Antibodies for BIK

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BIK Gene

protein-coding GIFtS: 63

Aliases &
Descriptions
for BIK

Summaries
for BIK

Genomic Location
for BIK

Proteins
for BIK

Protein Domains/
Families
for BIK

Gene Function
for BIK

Pathways & Interactions
for BIK

Drugs & Compounds
for BIK

Transcripts
for BIK

Expression
for BIK

Orthologs
for BIK

Paralogs
for BIK

SNPs/Variants
for BIK

Disorders & Mutations
for BIK

Medical News
for BIK

Publications
for BIK

Search for BIK

Genome Databases showing BIK

Other Databases showing BIK

Specialized Databases showing BIK

Licensable Technologies
for BIK

Services
for BIK

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

BIK Gene

protein-coding GIFtS: 63

Aliases & Descriptionsfor BIK

Summariesfor BIK

Genomic Locationfor BIK

Proteinsfor BIK

Protein Domains/Familiesfor BIK

Gene Functionfor BIK

Pathways & Interactionsfor BIK

Drugs & Compoundsfor BIK

Transcriptsfor BIK

Expression for BIK

Orthologsfor BIK

Paralogsfor BIK

SNPs/Variantsfor BIK

Disorders & Mutationsfor BIK

Medical Newsfor BIK

Publicationsfor BIK

Search for BIK

Genome Databases showing BIK

Other Databases showing BIK

Specialized Databases showing BIK

Licensable Technologiesfor BIK

Servicesfor BIK

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for BIK

Summaries
for BIK

Genomic Location
for BIK

Proteins
for BIK

Protein Domains/
Families
for BIK

Gene Function
for BIK

Pathways & Interactions
for BIK

Drugs & Compounds
for BIK

Transcripts
for BIK

Expression
for BIK

Orthologs
for BIK

Paralogs
for BIK

SNPs/Variants
for BIK

Disorders & Mutations
for BIK

Medical News
for BIK

Publications
for BIK

Licensable Technologies
for BIK

Services
for BIK