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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

BICD2 Gene

protein-coding   GIFtS: 52
GCID: GC09M095473

Bicaudal D Homolog 2 (Drosophila)

  Search for BICD2
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Bicaudal D Homolog 2 (Drosophila)1 2     Coiled-Coil Protein BICD22
Bic-D 22 3     Cytoskeleton-Like Bicaudal D Protein Homolog 22
KIAA06993 5     Homolog Of Drosophila Bicaudal D2
SMALED22     Protein Bicaudal D Homolog 22
bA526D8.12     

External Ids:    HGNC: 172081   Entrez Gene: 232992   Ensembl: ENSG000001859637   OMIM: 6097975   UniProtKB: Q8TD163   

Export aliases for BICD2 gene to outside databases

Previous GC identifers: GC09M086300 GC09M087201 GC09M088772 GC09M090815 GC09M090816 GC09M092553 GC09M094513 GC09M065151


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for BICD2 Gene:
This gene is one of two human homologs of Drosophila bicaudal-D and a member of the Bicoid family. It has been
implicated in dynein-mediated, minus end-directed motility along microtubules. It has also been reported to be a
phosphorylation target of NIMA related kinase 8. Two alternative splice variants have been described. (provided
by RefSeq, Jul 2008)

GeneCards Summary for BICD2 Gene: 
BICD2 (bicaudal D homolog 2 (Drosophila)) is a protein-coding gene. GO annotations related to this gene include protein binding and Rab GTPase binding. An important paralog of this gene is BICD1.

UniProtKB/Swiss-Prot: BICD2_HUMAN, Q8TD16
Function: May play a role in the dynein-dynactin interactions on the surface of membranous organelles, by
associating with these complexes. Regulates coat complex coatomer protein I (COPI)-independent Golgi-endoplasmic
reticulum transport by recruiting the dynein-dynactin motor complex (By similarity)

Gene Wiki entry for BICD2 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000009.11  NC_018920.2  NT_008470.19  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the BICD2 gene promoter:
         NF-YA   NF-YC   CBF-C   NF-YB   CBF-A   CBF-B   CP1A   CP1C   NF-Y   CBF(2)   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidBICD2 promoter sequence
   Search SABiosciences Chromatin IP Primers for BICD2

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat BICD2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 9q22.31   Ensembl cytogenetic band:  9q22.31   HGNC cytogenetic band: 9q22.32

BICD2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
BICD2 gene location

GeneLoc information about chromosome 9         GeneLoc Exon Structure

GeneLoc location for GC09M095473:  view genomic region     (about GC identifiers)

Start:
95,473,645 bp from pter      End:
95,527,094 bp from pter
Size:
53,450 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: BICD2_HUMAN, Q8TD16 (See protein sequence)
Recommended Name: Protein bicaudal D homolog 2  
Size: 824 amino acids; 93533 Da
Subunit: Interacts with DCTN2 and RAB6A (By similarity). Interacts with NEK9
Subcellular location: Golgi apparatus. Cytoplasm, cytoskeleton. Note=In interphase cells mainly localizes to the
Golgi complex and colocalizes with dynactin at microtubule plus ends (By similarity). Its localization is
dependent on microtubule morphology
Sequence caution: Sequence=BAA31674.1; Type=Erroneous initiation;
Secondary accessions: O75181 Q5TBQ2 Q5TBQ3 Q96LH2 Q9BT84 Q9H561
Alternative splicing: 2 isoforms:  Q8TD16-1   Q8TD16-2   (Due to intron retention. No experimental confirmation available)

Explore the universe of human proteins at neXtProt for BICD2: NX_Q8TD16

Explore proteomics data for BICD2 at MOPED 

Post-translational modifications:

  • UniProtKB: Phosphorylated by NEK9 in vitro
  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q8TD16

  • BICD2 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    BICD2 Protein Expression
    REFSEQ proteins (2 alternative transcripts): 
    NP_001003800.1  NP_056065.1  

    ENSEMBL proteins: 
     ENSP00000349351   ENSP00000364662  

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    Gene Ontology (GO): 5 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm IDA--
    GO:0005794Golgi apparatus IDA--
    GO:0005856cytoskeleton IEA--
    GO:0005886plasma membrane IDA--
    GO:0031410cytoplasmic vesicle ISS--

    BICD2 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    1 InterPro protein domain:
     IPR018477 Bicaudal-D_microtubule-assoc

    Graphical View of Domain Structure for InterPro Entry Q8TD16

    ProtoNet protein and cluster: Q8TD16

    UniProtKB/Swiss-Prot: BICD2_HUMAN, Q8TD16
    Domain: The fourth coiled coil region is involved in Golgi targeting and in the interaction with DCTN2 (By
    similarity)
    Similarity: Belongs to the BicD family


    BICD2 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: BICD2_HUMAN, Q8TD16
    Function: May play a role in the dynein-dynactin interactions on the surface of membranous organelles, by
    associating with these complexes. Regulates coat complex coatomer protein I (COPI)-independent Golgi-endoplasmic
    reticulum transport by recruiting the dynein-dynactin motor complex (By similarity)

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI16417406
    GO:0017137Rab GTPase binding ISS--
         
    BICD2 for ontologies           About GeneDecksing


    Animal Models:
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for BICD2

    STRING Interaction Network Preview (showing 5 interactants - click image to see 14)

    5/15 Interacting proteins for BICD2 (Q8TD163 ENSP000003493514) via UniProtKB, MINT, STRING, and/or I2D (see all 15)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    DCTN2Q135613, ENSP000004089104I2D: score=3 STRING: ENSP00000408910
    DCTN1Q142033, ENSP000003547914I2D: score=2 STRING: ENSP00000354791
    ZRANB1Q9UGI03, ENSP000003526764I2D: score=2 STRING: ENSP00000352676
    GSK3BP498413, ENSP000003248064I2D: score=1 STRING: ENSP00000324806
    NEK8Q86SG63, ENSP000002687664I2D: score=1 STRING: ENSP00000268766
    About this table

    Gene Ontology (GO): 4 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006810transport ----
    GO:0007018microtubule-based movement ----
    GO:0072385minus-end-directed organelle transport along microtubule ISS--
    GO:0072393microtubule anchoring at microtubule organizing center ISS--

    BICD2 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
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    Browse Tocris compounds for BICD2

    Search CenterWatch for drugs/clinical trials and news about BICD2

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for BICD2 gene (2 alternative transcripts): 
    NM_001003800.1  NM_015250.3  

    Unigene Cluster for BICD2:

    Bicaudal D homolog 2 (Drosophila)
    Hs.436939  [show with all ESTs]
    Unigene Representative Sequence: BC073970
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000356884(uc004asp.1) ENST00000375512(uc004aso.1)
    miRNA
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    hsa-miR-411* hsa-miR-193a-3p hsa-miR-106a hsa-miR-218-1* hsa-miR-578 hsa-miR-519a hsa-miR-93 hsa-miR-200b
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    Additional mRNA sequence: 

    AB014599.1 AY052562.1 BC004296.1 BC010428.1 BC073970.1 

    6 DOTS entries:

    DT.97803436  DT.80100690  DT.121188556  DT.100815322  DT.91914250  DT.99976382 

    24/246 AceView cDNA sequences (see all 246):

    CA428462 BU839273 CA439423 AW612194 BM981859 AI138873 AB014599 BU626377 
    BF476382 AI140257 N89907 CF147462 AI202770 AW131261 BU947613 AY052562 
    NM_001003800 Z42312 AI597762 AI080012 AA621608 BM677805 BE046492 T11454 

    GeneLoc Exon Structure

    2 Alternative Splicing Database (ASD) splice patterns (SP) for BICD2    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8a · 8b
    SP1:                                                      
    SP2:                                                      


    ECgene alternative splicing isoforms for BICD2

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    BICD2 expression in normal human tissues (normalized intensities)      BICD2 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GAAAAGGAAT
    BICD2 Expression
    About this image


    BICD2 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/19 selected tissues (see all 19) fully expand
     
     Brain (Nervous System)    fully expand to see all 8 entries
             Medulla Oblongata
             ganglion/cranial/facial VII   
     
     Neural Tube (Nervous System)    fully expand to see all 7 entries
             Metencephalon
             spinal cord/lateral wall/ventricular layer   
     
     Epithelium (Reproductive System)    fully expand to see all 4 entries
             vagina ; squamous epithelial cells   
     
     Peripheral Nervous System (Nervous System)    fully expand to see all 2 entries
             colon ; peripheral nerve/ganglion   
             spinal/ganglion/dorsal root ganglion   
     
     Tonsil (Hematopoietic System)    fully expand to see all 2 entries
             tonsil ; squamous epithelial cells   

    See BICD2 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for BICD2

    SOURCE GeneReport for Unigene cluster: Hs.436939

    UniProtKB/Swiss-Prot: BICD2_HUMAN, Q8TD16
    Tissue specificity: Ubiquitous

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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for BICD2 gene from 7/16 species (see all 16)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Bicd21 , 5 bicaudal D homolog 2 (Drosophila)1, 5 90.11(n)1
    95.64(a)1
      13 (25.22 cM)5
    768951  NM_001039179.11  NP_001034268.11 
     493415495 
    chicken
    (Gallus gallus)
    Aves BICD21 bicaudal D homolog 2 (Drosophila) 75.72(n)
    83.05(a)
      415990  XM_414332.3  XP_414332.3 
    lizard
    (Anolis carolinensis)
    Reptilia BICD26
    --
    --
    82(a)
    44(a)
    1 ↔ 1
    possible ortholog
    GL343225.1(2235799-2290863)
    2(88709332-88735372)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.269432 Xenopus laevis transcribed sequence with weak similarity more 75.13(n)    BU914482.1 
    zebrafish
    (Danio rerio)
    Actinopterygii LOC5573831 protein bicaudal D homolog 2-like 67.91(n)
    71.15(a)
      557383  XM_680437.2  XP_685529.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta BicD3 egg chamber formation 38(a)   2 36C9   --
    worm
    (Caenorhabditis elegans)
    Secernentea C43G2.23 cytoskeleton-like protein 30(a)   IV(6566088-6572516)   --


    ENSEMBL Gene Tree for BICD2 (if available)
    TreeFam Gene Tree for BICD2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for BICD2 gene
    BICD12  
    1 SIMAP similar gene for BICD2 using alignment to 2 protein entries:     BICD2_HUMAN (see all proteins):
    BICD1

    BICD2 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/1132 SNPs in BICD2 are shown (see all 1132)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 9 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs132865661,2
    C,F,A--95473178(+) TCTTAC/TCAACA 2 -- ds500113Minor allele frequency- T:0.39NA WA CSA EA 514
    rs789445061,2
    C,F--95473248(+) GAGGCG/ATCAGG 2 -- ds50011Minor allele frequency- A:0.02WA 118
    rs1461112811,2
    C--95473280(+) TCCAGG/TGGGGG 2 -- ds50010--------
    rs1839134961,2
    --95473286(+) GGGGGA/GCATTG 2 -- ds50010--------
    rs1389788151,2
    --95473545(+) TGATAA/GGCTTG 2 -- ds50010--------
    rs1903416721,2
    --95473615(+) GAGCAC/TGGAGT 2 -- ds50010--------
    rs1422323501,2
    --95473616(+) AGCACA/GGAGTC 2 -- ds50010--------
    rs1825986991,2
    --95473620(+) CGGAGA/TCAGAA 2 -- ds50010--------
    rs1871980561,2
    C--95473645(+) AAACAA/TGTGCT 2 -- ut310--------
    rs5561,2
    C,F,O,A,H--95473719(+) TATGCG/ACACTG 2 -- ut31 ese333Minor allele frequency- A:0.42MN NS EA NA WA 4200

    HapMap Linkage Disequilibrium report for BICD2 (95473645 - 95527094 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for BICD2:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv999632CNV Deletion20482838
    nsv6616CNV Insertion18451855

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    BICD2 for disorders           About MalaCards
    OMIM gene information: 609797    OMIM disorders: --


    BICD2 for disorders           About GeneDecksing


    Export disorders for BICD2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for BICD2 gene, integrated from 9 sources (see all 33):
    (articles sorted by number of sources associating them with BICD2)
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    1. Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. (PubMed id 9734811)1, 2, 3 Ishikawa K.... Ohara O. (1998)
    2. Purification, cloning, and characterization of Nek8, a novel NIMA- related kinase, and its candidate substrate Bicd2. (PubMed id 11864968)1, 2, 9 Holland P.M.... Virca G.D. (2002)
    3. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (2006)
    4. DNA sequence and analysis of human chromosome 9. (PubMed id 15164053)1, 2 Humphray S.J.... Dunham I. (2004)
    5. Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using immobilized metal affinity chromatography and tandem mass spectrometry. (PubMed id 15144186)1, 2 Brill L.M....Peters E.C. (2004)
    6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    7. Interlaboratory reproducibility of large-scale human p rotein-complex analysis by standardized AP-MS. (PubMed id 23455922)1 Varjosalo M....Superti-Furga G. (2013)
    8. Global landscape of HIV-human protein complexes. (PubMed id 22190034)1 Jager S....Krogan N.J. (2012)
    9. Genome-wide association for abdominal subcutaneous and visceral adipose reveals a novel locus for visceral fat in women. (PubMed id 22589738)1 Fox C.S....Borecki I.B. (2012)
    10. Human Asunder promotes dynein recruitment and centroso mal tethering to the nucleus at mitotic entry. (PubMed id 23097494)1 Jodoin J.N....Lee L.A. (2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 23299 HGNC: 17208 AceView: BICD2 Ensembl:ENSG00000185963 euGenes: HUgn23299
    ECgene: BICD2 H-InvDB: BICD2

    (According to HUGE)
    About This Section
    HUGE: KIAA0699

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for BICD2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for BICD2 gene:
    Search GeneIP for patents involving BICD2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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