Aliases for BICD1 Gene
External Ids for BICD1 Gene
Previous GeneCards Identifiers for BICD1 Gene
This gene is one of two human homologs of Drosophila bicaudal-D. It has been implicated in COPI-independent membrane transport from the Golgi apparatus to the endoplasmic reticulum. Two alternative splice variants have been described. Other alternative splice variants that encode different protein isoforms have been described but their full-length nature has not been determined. [provided by RefSeq, Jul 2008]
GeneCards Summary for BICD1 Gene
BICD1 (BICD Cargo Adaptor 1) is a Protein Coding gene. Diseases associated with BICD1 include Lissencephaly 1. Among its related pathways are Vesicle-mediated transport and COPI-independent Golgi-to-ER retrograde traffic. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding and structural constituent of cytoskeleton. An important paralog of this gene is BICD2.
UniProtKB/Swiss-Prot for BICD1 Gene
Regulates coat complex coatomer protein I (COPI)-independent Golgi-endoplasmic reticulum transport by recruiting the dynein-dynactin motor complex.