Aliases for BHLHE23 Gene
External Ids for BHLHE23 Gene
Previous HGNC Symbols for BHLHE23 Gene
Previous GeneCards Identifiers for BHLHE23 Gene
This gene encodes a member of the basic helix-loop-helix transcription factor family. Members of this family contain two highly conserved and functionally distinct domains: the basic domain targets sequence-specific DNA binding, while the helix-loop-helix domain facilitates protein interaction. Studies of a related gene in mouse suggest that the encoded protein may function as a transcriptional repressor in the pancreas and brain, and that it is required for normal retinal function. [provided by RefSeq, May 2013]
GeneCards Summary for BHLHE23 Gene
BHLHE23 (Basic Helix-Loop-Helix Family Member E23) is a Protein Coding gene. GO annotations related to this gene include protein dimerization activity. An important paralog of this gene is BHLHE22.
UniProtKB/Swiss-Prot for BHLHE23 Gene
May function as transcriptional repressor. May modulate the expression of genes required for the differentiation and/or maintenance of pancreatic and neuronal cell types. May be important for rod bipolar cell maturation (By similarity).