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BHLHB9 Gene

protein-coding   GIFtS: 50
GCID: GC0XP101975

Basic Helix-Loop-Helix Domain Containing, Class B, 9

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA

Quality score for the ORGUL clustered with this gene is 3

Aliases
Basic Helix-Loop-Helix Domain Containing, Class B, 91 2     P60-Like Protein2
Transcription Regulator Of 60 KDa2 3     Protein BHLHb92
p60TRP2 3     KIAA17013
GASP32     bHLHb93

External Ids:    HGNC: 293531   Entrez Gene: 808232   Ensembl: ENSG000001989087   UniProtKB: Q6PI773   
ORGUL members:         

Export aliases for BHLHB9 gene to outside databases

Previous GC identifers: GC0XP101781 GC0XP101865 GC0XP091573


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for BHLHB9 Gene:
This gene is a member of a gene family which encodes proteins with a basic helix-loop-helix domain. Other members
of this gene family encode proteins which function as transcription factors, either enhancing or inhibiting
transcription depending on the activity of other DNA binding proteins. The coding region of this gene is located
entirely within the terminal exon. The encoded protein may be involved in the survival of neurons (PMID:
15034937). Multiple alternatively spliced variants, encoding the same protein, have been identified. (provided by
RefSeq, Sep 2011)

GeneCards Summary for BHLHB9 Gene:
BHLHB9 (basic helix-loop-helix domain containing, class B, 9) is a protein-coding gene. An important paralog of this gene is GPRASP2.

UniProtKB/Swiss-Prot: BHLH9_HUMAN, Q6PI77
Function: May play a role in the control of cellular aging and survival




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000023.10  NC_018934.2  NT_011651.18  
Regulatory elements:
   Regulatory transcription factor binding sites in the BHLHB9 gene promoter:
         AREB6   AML1a   POU3F1   NF-kappaB2   Egr-1   HSF1 (long)   Nkx2-5   NF-kappaB   NF-kappaB1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidBHLHB9 promoter sequence
   Search Chromatin IP Primers for BHLHB9

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat BHLHB9


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: Xq23   Ensembl cytogenetic band:  Xq22.1   HGNC cytogenetic band: Xq23

BHLHB9 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
BHLHB9 gene location

GeneLoc information about chromosome X         GeneLoc Exon Structure

GeneLoc location for GC0XP101975:  view genomic region     (about GC identifiers)

Start:
101,975,616 bp from pter      End:
102,008,468 bp from pter
Size:
32,853 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: BHLH9_HUMAN, Q6PI77 (See protein sequence)
Recommended Name: Protein BHLHb9  
Size: 547 amino acids; 60291 Da
Caution: Despite its name, no basic helix-loop-helix (bHLH) domain is detected by any prediction tool
Sequence caution: Sequence=BAB21792.1; Type=Erroneous initiation;
Secondary accessions: Q9C0G2

Explore the universe of human proteins at neXtProt for BHLHB9: NX_Q6PI77

Explore proteomics data for BHLHB9 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys342
  • Modification sites at PhosphoSitePlus

  • See BHLHB9 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (8 alternative transcripts): 
    NP_001135996.1  NP_001135997.1  NP_001135998.1  NP_001135999.1  NP_001136000.1  NP_001136001.1  NP_001136002.1  NP_085142.1  

    ENSEMBL proteins: 
     ENSP00000354675   ENSP00000361820   ENSP00000403226   ENSP00000405893   ENSP00000391722  

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    ARMC: Armadillo repeat containing
    bHLH: Basic helix-loop-helix proteins

    3 InterPro protein domains:
     IPR011989 ARM-like
     IPR006911 ARM-rpt_dom
     IPR016024 ARM-type_fold

    Graphical View of Domain Structure for InterPro Entry Q6PI77

    ProtoNet protein and cluster: Q6PI77

    UniProtKB/Swiss-Prot: BHLH9_HUMAN, Q6PI77
    Similarity: Belongs to the GPRASP family


    Find genes that share domains with BHLHB9           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: BHLH9_HUMAN, Q6PI77
    Function: May play a role in the control of cellular aging and survival
    Induction: Down-regulated in colon cancer cells, due to CpG hypermethylation of its promoter

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005488binding ----
    GO:0042803protein homodimerization activity ISS--
         
    Find genes that share ontologies with BHLHB9           About GenesLikeMe


    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for BHLHB9

    miRNA
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    miRTarBase miRNAs that target BHLHB9:
    hsa-mir-425-5p (MIRT016652)

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    Selected qRT-PCR Assays for microRNAs that regulate BHLHB9 (see all 16):
    hsa-miR-34c-3p hsa-miR-582-3p hsa-miR-579 hsa-miR-24-1* hsa-miR-708* hsa-miR-551b* hsa-miR-3923 hsa-miR-664
    SwitchGear 3'UTR luciferase reporter plasmidBHLHB9 3' UTR sequence
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    BHLH9_HUMAN, Q6PI77: Cytoplasm. Nucleus. Note=Mainly cytoplasmic, and nuclear at lower level
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus5
    cytosol2

    Gene Ontology (GO): 3 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IEA--
    GO:0005737cytoplasm IEA--
    GO:0070062extracellular vesicular exosome IDA19056867

    Find genes that share ontologies with BHLHB9           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for BHLHB9
    Interactions:

        Search GeneGlobe Interaction Network for BHLHB9

    STRING Interaction Network Preview (showing 3 interactants - click image to see more details)

    3 Interacting proteins for BHLHB9 (Q6PI773 ENSP000003546754) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    IPO5O004103, ENSP000002615744I2D: score=1 STRING: ENSP00000261574
    PPP2R5EQ165373, ENSP000003376414I2D: score=1 STRING: ENSP00000337641
    UBCENSP000003448184STRING: ENSP00000344818
    About this table

    Gene Ontology (GO): 5 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007611learning or memory ISS--
    GO:0043524negative regulation of neuron apoptotic process ISS--
    GO:0050769positive regulation of neurogenesis ISS--
    GO:0051965positive regulation of synapse assembly ISS--
    GO:0061003positive regulation of dendritic spine morphogenesis ISS--

    Find genes that share ontologies with BHLHB9           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for BHLHB9 (BHLH9)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for BHLHB9 gene (8 alternative transcripts): 
    NM_001142524.1  NM_001142525.1  NM_001142526.1  NM_001142527.1  NM_001142528.1  NM_001142529.1  NM_001142530.1  NM_030639.2  

    Unigene Cluster for BHLHB9:

    Basic helix-loop-helix domain containing, class B, 9
    Hs.4276  [show with all ESTs]
    Unigene Representative Sequence: NM_001142524
    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000483294 ENST00000361229 ENST00000486988 ENST00000372735 ENST00000457056(uc010nog.3 uc011mrq.2 uc011mrr.2 uc011mrs.2 uc011mrt.2 uc004ejo.3)
    ENST00000447531(uc011mru.2) ENST00000448867(uc011mrv.2)
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    hsa-miR-34c-3p hsa-miR-582-3p hsa-miR-579 hsa-miR-24-1* hsa-miR-708* hsa-miR-551b* hsa-miR-3923 hsa-miR-664
    SwitchGear 3'UTR luciferase reporter plasmidBHLHB9 3' UTR sequence
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    Additional mRNA sequence: 

    AB051488.1 AF035288.1 AF547055.1 AK054934.1 BC041409.2 

    14 DOTS entries:

    DT.95101844  DT.414780  DT.121305774  DT.121305744  DT.95362962  DT.95205075  DT.121305742  DT.100746259 
    DT.121305613  DT.121305675  DT.121305813  DT.95362963  DT.97766110  DT.121305677 

    Selected AceView cDNA sequences (see all 50):

    BC041409 CD656228 BE044386 AB051488 AK054934 AA970070 Z42961 BM987572 
    BM788325 NM_030639 Z39080 N64005 CA335213 BQ721693 AF035288 BX503788 
    BE735754 AA970925 AA192962 H11797 T32425 CD244544 T10236 AF547055 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for BHLHB9 (see all 12)    About this scheme

    ExUns: 1a · 1b · 1c · 1d ^ 2a · 2b ^ 3 ^ 4a · 4b ^ 5a · 5b ^ 6a · 6b · 6c · 6d · 6e · 6f · 6g · 6h
    SP1:                                -     -     -     -                                                               
    SP2:                                      -     -     -                                                               
    SP3:                                -     -     -     -     -                                                         
    SP4:                                      -     -     -     -                                                         
    SP5:                                -     -     -     -     -                                                         


    ECgene alternative splicing isoforms for BHLHB9

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    BHLHB9 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TCAATAAATA
    BHLHB9 Expression
    About this image


    BHLHB9 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 3) fully expand
     
     Epithelial Cells
             Presumptive Podocytes Podocyte Layer
     
     Bone (Muscoskeletal System)
             Endochondral Facial Bones
     
     Kidney (Urinary System)
             Presumptive Podocytes Podocyte Layer
    BHLHB9 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    BHLHB9 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.4276

    UniProtKB/Swiss-Prot: BHLH9_HUMAN, Q6PI77
    Tissue specificity: Highly expressed in brain. Not expressed in lung or liver. Down-regulated in brain from
    patients suffering from Alzheimer disease

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for BHLHB9

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for BHLHB9 gene from Selected species (see all 9)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Bhlhb91 , 5 basic helix-loop-helix domain containing, class B91, 5 80.45(n)1
    74.67(a)1
      X (57.31 cM)5
    702371  NM_198161.21  NP_937804.11 
     1358858535 
    chicken
    (Gallus gallus)
    Aves --
    Uncharacterized protein
    21(a)
    1 → many
    1(12726364-12735694)
    lizard
    (Anolis carolinensis)
    Reptilia --
    Uncharacterized protein
    18(a)
    1 → many
    5(95300984-95312074)
    zebrafish
    (Danio rerio)
    Actinopterygii ARMCX36
    armadillo repeat containing, X-linked 3
    16(a)
    1 → many
    25(19368321-19378457) ENSDARG00000062960


    ENSEMBL Gene Tree for BHLHB9 (if available)
    TreeFam Gene Tree for BHLHB9 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for BHLHB9 gene
    GPRASP22  ARMCX12  ARMCX22  ARMCX52  GPRASP12  ARMCX62  ARMC102  ARMCX32  
    1 SIMAP similar gene for BHLHB9 using alignment to 1 protein entry:     BHLH9_HUMAN:
    ARMCX5

    Find genes that share paralogs with BHLHB9           About GenesLikeMe


    1 Pseudogenes.org Pseudogene for BHLHB9
    PGOHUM00000248241


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for BHLHB9 (see all 417)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr X posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs591077441,2
    C--101942864(+) AGAAAA/GACTAG 6 -- us2k10--------
    rs1853012801,2
    --101942869(+) GACTAA/GCTTTT 6 -- us2k10--------
    rs1890310421,2
    --101942947(+) CCTTTA/GGGAGG 6 -- us2k10--------
    rs1814257301,2
    --101942981(+) CTCAAC/GAGTTC 6 -- us2k10--------
    rs1855189021,2
    --101943196(+) AAAAAA/TAAAAT 6 -- us2k10--------
    rs1425682411,2
    --101943208(+) AAATAA/TAATAA 6 -- us2k10--------
    rs1899108601,2
    --101943352(+) ATACAA/CAAACT 6 -- us2k10--------
    rs105461291,2
    C--101943367(+) caggc-/ATGgtggt 6 -- us2k11Minor allele frequency- ATG:0.00CSA 2
    rs113361431,2
    F--101943514(+) AAAAAA/-AAAAA 6 -- us2k1 trp32Minor allele frequency- -:0.50NA CSA 4
    rs78779341,2
    C,F,A--101943710(+) aaatgG/Ttaaat 6 -- us2k1 tfbs31Minor allele frequency- T:0.00CSA 1

    HapMap Linkage Disequilibrium report for BHLHB9 (101975616 - 102008468 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for BHLHB9:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv526716CNV Gain19592680

    Locus Specific Mutation Databases (LSDB): BHLHB9

    Site Specific Mutation Identification with PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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      --

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for BHLHB9 gene, integrated from 10 sources (see all 15):
    (articles sorted by number of sources associating them with BHLHB9)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Characterizing the new transcription regulator protein p60TRP. (PubMed id 15034937)1, 2, 3 Heese K....Sawada T. (J. Cell. Biochem. 2004)
    2. Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 11214970)1, 2, 3 Nagase T.... Ohara O. (DNA Res. 2000)
    3. Mammalian BEX, WEX and GASP genes: coding and non-coding chimaerism sustained by gene conversion events. (PubMed id 16221301)1, 3 Winter E.E. and Ponting C.P. (BMC Evol. Biol. 2005)
    4. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PubMed id 23000965)1 Povlsen L.K....Choudhary C. (Nat. Cell Biol. 2012)
    5. Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PubMed id 21832049)1 OlA!h J....OvA!di J. (J. Biol. Chem. 2011)
    6. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (amp 2011)
    7. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (amp 2011)
    8. Large-scale proteomics and phosphoproteomics of urinary exosomes. (PubMed id 19056867)1 Gonzales P.A....Knepper M.A. (J. Am. Soc. Nephrol. 2009)
    9. Discovery of epigenetically silenced genes by methylated DNA immunoprecipitation in colon cancer cells. (PubMed id 18089774)2 Jacinto F.V.... Esteller M. (Cancer Res. 2007)
    10. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (Genome Res. 2006)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
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      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 80823 HGNC: 29353 AceView: BHLHB9 Ensembl:ENSG00000198908 euGenes: HUgn80823
    ECgene: BHLHB9 H-InvDB: BHLHB9

    (According to HUGE)
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    HUGE: KIAA1701

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for BHLHB9 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for BHLHB9 gene:
    Search GeneIP for patents involving BHLHB9

    GeneCards and IP:
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