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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

BHLHA15 Gene

protein-coding   GIFtS: 52
GCID: GC07P097841

Basic Helix-Loop-Helix Family, Member A15

(Previous names: basic helix-loop-helix domain containing, class B, 8)
(Previous symbol: BHLHB8)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Basic Helix-Loop-Helix Family, Member A151 2     MIST12 3
BHLHB81 2 3     Class A Basic Helix-Loop-Helix Protein 152
Basic Helix-Loop-Helix Domain Containing, Class B, 81 2     Class II BHLH Protein MIST12
Class B Basic Helix-Loop-Helix Protein 82 3     bHLHa153
Muscle, Intestine And Stomach Expression 12 3     bHLHb83
MIST-12 3     

External Ids:    HGNC: 222651   Entrez Gene: 1686202   Ensembl: ENSG000001805357   OMIM: 6086065   UniProtKB: Q7RTS13   

Export aliases for BHLHA15 gene to outside databases

Previous GC identifers: GC07P097680 GC07P092442


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for BHLHA15 Gene: 
BHLHA15 (basic helix-loop-helix family, member a15) is a protein-coding gene. Diseases associated with BHLHA15 include pancreatic ductal adenocarcinoma, and maturity-onset diabetes of the young, and among its related super-pathways are Regulation of beta-cell development. GO annotations related to this gene include DNA binding and protein homodimerization activity. An important paralog of this gene is NEUROG3.

UniProtKB/Swiss-Prot: BHA15_HUMAN, Q7RTS1
Function: Plays a role in controlling the transcriptional activity of MYOD1, ensuring that expanding myoblast
populations remain undifferentiated. Repression may occur through muscle-specific E-box occupancy by homodimers.
May also negatively regulate bHLH-mediated transcription through an N-terminal repressor domain. Serves as a key
regulator of acinar cell function, stability, and identity. Also required for normal organelle localization in
exocrine cells and for mitochondrial calcium ion transport. May function as a unique regulator of gene expression
in several different embryonic and postnatal cell lineages. Binds to the E-box consensus sequence 5'-CANNTG-3'
(By similarity)

Gene Wiki entry for BHLHA15 (BHLHB8) Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000007.13  NT_007933.15  NC_018918.2  NT_079595.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the BHLHA15 gene promoter:
         NF-1/L   NF-1   AML1a   deltaCREB   STAT3   LUN-1   CUTL1   C/EBPalpha   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): BHLHA15 promoter sequence
   Search SABiosciences Chromatin IP Primers for BHLHA15

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat BHLHA15


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 7q21.3   Ensembl cytogenetic band:  7q21.3   HGNC cytogenetic band: 7q21.3

BHLHA15 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
BHLHA15 gene location

GeneLoc information about chromosome 7         GeneLoc Exon Structure

GeneLoc location for GC07P097841:  view genomic region     (about GC identifiers)

Start:
97,841,566 bp from pter      End:
97,842,271 bp from pter
Size:
706 bases      Orientation:
plus strand

1 alternative location:
Chr7+,CRA_TCAG 97,166,444-97,167,149     

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: BHA15_HUMAN, Q7RTS1 (See protein sequence)
Recommended Name: Class A basic helix-loop-helix protein 15  
Size: 189 amino acids; 20818 Da
Subunit: Forms homodimers or heterodimers with TCF3 gene products E12 and E47. These dimers bind to the E-box
site, however, heterodimer with MYOD1 does not bind target DNA (By similarity)
Subcellular location: Nucleus (Probable)
Secondary accessions: A4D271 Q14DE4

Explore the universe of human proteins at neXtProt for BHLHA15: NX_Q7RTS1

Explore proteomics data for BHLHA15 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q7RTS1

  • BHLHA15 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    BHLHA15 Protein Expression
    REFSEQ proteins: NP_803238.1  
    ENSEMBL proteins: 
     ENSP00000326391  

    Human Recombinant Protein Products for BHLHA15: 
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    Browse Proteins at Cloud-Clone Corp. 

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IEA--

    BHLHA15 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    bHLH: Basic helix-loop-helix proteins

    1 InterPro protein domain:
     IPR011598 bHLH_dom

    Graphical View of Domain Structure for InterPro Entry Q7RTS1

    ProtoNet protein and cluster: Q7RTS1

    1 Blocks protein domain: IPB001092 Basic helix-loop-helix dimerization domain bHLH

    UniProtKB/Swiss-Prot: BHA15_HUMAN, Q7RTS1
    Domain: Lacks a classic transcription activation domain and instead possesses an N-terminal region capable of
    inhibiting heterologous activators (By similarity)
    Similarity: Contains 1 bHLH (basic helix-loop-helix) domain


    BHLHA15 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: BHA15_HUMAN, Q7RTS1
    Function: Plays a role in controlling the transcriptional activity of MYOD1, ensuring that expanding myoblast
    populations remain undifferentiated. Repression may occur through muscle-specific E-box occupancy by homodimers.
    May also negatively regulate bHLH-mediated transcription through an N-terminal repressor domain. Serves as a key
    regulator of acinar cell function, stability, and identity. Also required for normal organelle localization in
    exocrine cells and for mitochondrial calcium ion transport. May function as a unique regulator of gene expression
    in several different embryonic and postnatal cell lineages. Binds to the E-box consensus sequence 5'-CANNTG-3'
    (By similarity)

         Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003677DNA binding IEA--
    GO:0042803protein homodimerization activity IEA--
    GO:0046983protein dimerization activity ----
         
    BHLHA15 for ontologies           About GeneDecksing


    Phenotypes:
         7 MGI mutant phenotypes (inferred from 3 alleles(MGI details for Bhlha15):
     digestive/alimentary  endocrine/exocrine gland  growth/size  homeostasis/metabolism  liver/biliary system 
     mortality/aging  tumorigenesis 

    BHLHA15 for phenotypes           About GeneDecksing

    Animal Models:
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for BHLHA15


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for BHLHA15 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Regulation of beta-cell development
    Maturity onset diabetes of the young0.56

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways



    1         Kegg Pathway  (Kegg details for BHLHA15):
        Maturity onset diabetes of the young


    BHLHA15 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for BHLHA15

    STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

    2 Interacting proteins for BHLHA15 (Q7RTS13 ENSP000003263914) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    MYOD1P151723, ENSP000002500034I2D: score=1 STRING: ENSP00000250003
    TCF3P159233, ENSP000002629654I2D: score=1 STRING: ENSP00000262965
    About this table

    Gene Ontology (GO): 5/10 biological process terms (GO ID links to tree view) (see all 10):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006351transcription, DNA-dependent IEA--
    GO:0006851mitochondrial calcium ion transport IEA--
    GO:0007030Golgi organization IEA--
    GO:0007186G-protein coupled receptor signaling pathway IEA--
    GO:0007267cell-cell signaling IEA--

    BHLHA15 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for BHLHA15 (BHA15)

    1 HMDB Compound for BHLHA15    About this table
    CompoundSynonyms CAS #PubMed Ids
    CalciumCa (see all 2)7440-70-2--

    Search CenterWatch for drugs/clinical trials and news about BHLHA15 / BHA15

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
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    About This Section

    REFSEQ mRNAs for BHLHA15 gene: 
    NM_177455.3  

    Unigene Cluster for BHLHA15:

    Basic helix-loop-helix family, member a15
    Hs.674510
    Unigene Representative Sequence: NM_177455
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000314018(uc003upf.1 uc022ahw.1)
    miRNA
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    Additional mRNA sequence: 

    BC113394.1 BC113396.1 

    1 DOTS entry:

    DT.86857382 

    24/26 AceView cDNA sequences (see all 26):

    BK000276 NM_177455 AA367338 BU102064 CF135082 BX648200 CB050328 BF513674 
    CB049461 BM794468 AI620424 CB049462 BF000580 BQ636805 R20110 AA809519 
    CB050327 R43162 T83424 BM809037 AW955845 H90438 R19096 R35371 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    BHLHA15 expression in normal human tissues (normalized intensities)      BHLHA15 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TCCAGCAGCC
    BHLHA15 Expression
    About this image


    BHLHA15 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/5 selected tissues (see all 5) fully expand
     
     Pancreas (Endocrine System)    fully expand to see all 4 entries
             Acinar Cells Pancreatic Acini
             pancreas ; exocrine glandular cells   
     
     Stomach (Gastrointestinal Tract)    fully expand to see all 2 entries
             stomach, upper ; glandular cells   
     
     Tonsil (Hematopoietic System)
             tonsil ; non-germinal center cells   
     
     Lymph (Hematopoietic System)
             lymph node ; non-germinal center cells   
     
     Oral Cavity (Gastrointestinal Tract)
             salivary gland ; glandular cells   

    See BHLHA15 Protein Expression from SPIRE MOPED and PaxDB
    SOURCE GeneReport for Unigene cluster: Hs.674510

    UniProtKB/Swiss-Prot: BHA15_HUMAN, Q7RTS1
    Tissue specificity: Expressed in brain, liver, spleen and skeletal muscle

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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for BHLHA15 gene from 5/12 species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Bhlha151 , 5 basic helix-loop-helix family, member a151, 5 80.18(n)1
    83.78(a)1
      5 (83.05 cM)5
    173411  NM_010800.31  NP_034930.11 
     1441902865 
    chicken
    (Gallus gallus)
    Aves BHLHA151 basic helix-loop-helix family, member a15 69.31(n)
    75.25(a)
      427655  XM_425228.3  XP_425228.1 
    lizard
    (Anolis carolinensis)
    Reptilia BHLHA156
    Uncharacterized protein
    71(a)
    1 ↔ 1
    GL343507.1(470305-470661)
    zebrafish
    (Danio rerio)
    Actinopterygii bhlha151 basic helix-loop-helix family, member a15 60.14(n)
    54.05(a)
      777671  NM_001077652.1  NP_001071120.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta dimm6
    dimmed
    13(a)
    1 ↔ 1
    2L(21331756-21342155)


    ENSEMBL Gene Tree for BHLHA15 (if available)
    TreeFam Gene Tree for BHLHA15 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for BHLHA15 gene
    NEUROG32  NEUROD22  NEUROG22  NEUROD12  NEUROD62  ATOH12  ATOH72  NEUROG12  
    NEUROD42  
    2 SIMAP similar genes for BHLHA15 using alignment to 1 protein entry:     BHA15_HUMAN:
    BHLHE23    NEUROG3

    BHLHA15 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/79 SNPs in BHLHA15 are shown (see all 79)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 7 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs346161351,2
    C--92440983(+) GTGTC-/AGGGGGA 1 -- us2k12Minor allele frequency- AG:0.25NA 4
    rs19690061,2
    C,H--97839634(+) ttagcC/Tgggcg 1 -- us2k15Minor allele frequency- T:0.00NA CSA 9
    rs102617501,2
    C--97839717(+) aggttC/Gcggtg 1 -- us2k10--------
    rs19690071,2
    C,H--97839719(+) gttgcC/Ggtgag 1 -- us2k16Minor allele frequency- G:0.00NA WA CSA 11
    rs1434210131,2
    --97839775(+) CGAAAC/GTCCGT 1 -- us2k10--------
    rs592188251,2
    C--97839788(+) ACAAA-/CAAA  
            
    ACAGG
    1 -- us2k10--------
    rs787707861,2
    C--97839915(+) CCGGGC/GGGCGG 1 -- us2k10--------
    rs15323811,2
    C,F--97840024(+) CTGCCC/TCTCCT 1 -- us2k1 trp35Minor allele frequency- T:0.11MN NA CSA WA 308
    rs1176432881,2
    C,F--97840315(+) TCTTGG/CGGGGG 1 -- us2k11Minor allele frequency- C:0.20NA 120
    rs1821583641,2
    --97840392(+) GGGGAA/GGATGG 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for BHLHA15 (97841566 - 97842271 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 6 variations for BHLHA15:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv831066CNV Loss17160897
    nsv888760CNV Loss21882294
    nsv888762CNV Loss21882294
    dgv7395n71CNV Loss21882294
    nsv888763CNV Loss21882294
    nsv888765CNV Gain21882294

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 608606    OMIM disorders: --

    4 diseases for BHLHA15:    About MalaCards
    pancreatic ductal adenocarcinoma    maturity-onset diabetes of the young    adenocarcinoma    pancreatitis


    BHLHA15 for disorders           About GeneDecksing

    Genetic Association Database (GAD): BHLHA15
    Human Genome Epidemiology (HuGE) Navigator: BHLHA15 (1 document)

    Export disorders for BHLHA15 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for BHLHA15 gene, integrated from 9 sources (see all 21):
    (articles sorted by number of sources associating them with BHLHA15)
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    1. Exhaustive identification of human class II basic helix-loop-helix proteins by virtual library screening. (PubMed id 14516699)1, 2, 3 McLellan A.S.... Kealey T. (2002)
    2. Body mass index and von Hippel-Lindau gene mutations in clear-cell renal cancer: Results of the Netherlands Cohort Study on diet and cancer. (PubMed id 20382342)1, 4 Smits K.M....van den Brandt P.A. (2010)
    3. Phylogenetic and expression analysis of the basic helix-loop-helix transcription factor gene family: genomic approach to cellular differentiation. (PubMed id 18557763)1, 3 Stevens J.D....Skinner M.K. (2008)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    5. Human chromosome 7: DNA sequence and biology. (PubMed id 12690205)1, 2 Scherer S.W.... Tsui L.-C. (2003)
    6. The DNA sequence of human chromosome 7. (PubMed id 12853948)1, 2 Hillier L.W.... Wilson R.K. (2003)
    7. The basic helix-loop-helix transcription factor Mist1 functions as a transcriptional repressor of myoD. (PubMed id 9482738)1, 9 Lemercier C....Konieczny S.F. (1998)
    8. Activation of protein kinase Cd leads to increased pan creatic acinar cell dedifferentiation in the absence of MIST1. (PubMed id 22374815)1 Johnson C.L....Pin C.L. (2012)
    9. MIST1-a novel marker of plasmacytic differentiation. (PubMed id 22495370)1 Yeung C.C....Frater J.L. (2012)
    10. Biochemical and phosphoproteomic analysis of the helix -loop-helix protein E47. (PubMed id 22354994)1 Teachenor R....Murre C. (2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 168620 HGNC: 22265 AceView: MIST1 Ensembl:ENSG00000180535 euGenes: HUgn168620
    ECgene: BHLHA15 Kegg: 168620 H-InvDB: BHLHA15

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for BHLHA15 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for BHLHA15 gene:
    Search GeneIP for patents involving BHLHA15

    GeneCards and IP:
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