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CEACAM1 Gene

protein-coding   GIFtS: 63

GC19M047703
carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
(Previous symbol: BGP)
Services    

Aliases &
Descriptions
for CEACAM1

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc , and/or 7Ensembl, 8miRBase)
About This Section
Aliases
BGP 2, 3, 5
BGP-1 3
BGP1 1, 2, 3
BGPI 2
CD66a 1
Descriptions
Biliary glycoprotein 1 3
CD66a antigen 2, 3
antigen CD66 2
biliary glycoprotein adhesion molecule 2
carcinoembryonic antigen-related cell adhesion molecule 1 2
carcinoembryonic antigen-related cell adhesion molecule 1
(biliary glycoprotein) 2
External Ids
HGNC: 18141
Entrez Gene: 6342
UniProtKB: P136883
Ensembl: ENSG000000793857
Search outside databases for aliases for CEACAM1 gene

Previous GC identifers: GC19M043658 GC19M043403 GC19M047687

Summaries
for CEACAM1

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

 EntrezGene summary for CEACAM1:
This gene encodes a member of the carcinoembryonic antigen (CEA) gene family, which belongs to the
immunoglobulin superfamily. Two subgroups of the CEA family, the CEA cell adhesion molecules and
the pregnancy-specific glycoproteins, are located within a 1.2 Mb cluster on the long arm of
chromosome 19. Eleven pseudogenes of the CEA cell adhesion molecule subgroup are also found in the
cluster. The encoded protein was originally described in bile ducts of liver as biliary
glycoprotein. Subsequently, it was found to be a cell-cell adhesion molecule detected on
leukocytes, epithelia, and endothelia. The encoded protein mediates cell adhesion via homophilic
as well as heterophilic binding to other proteins of the subgroup. Multiple cellular activities
have been attributed to the encoded protein, including roles in the differentiation and
arrangement of tissue three-dimensional structure, angiogenesis, apoptosis, tumor suppression,
metastasis, and the modulation of innate and adaptive immune responses. Multiple transcript
variants encoding different isoforms have been reported, but the full-length nature of only two
has been determined. [provided by RefSeq]

Gene Wiki entry for CEACAM1

Genomic Location
for CEACAM1

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

 Genomic View:
UCSC Golden Path with GeneCards custom track

 Transcription factor binding sites upstream to the CEACAM1 gene  

Entrez Gene cytogenetic band: 19q13.2   Ensembl cytogenetic band:  19q13.2   HGNC cytogenetic band: 19q13.2

CEACAM1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 19         GeneLoc Exon Structure

GeneLoc location for GC19M047703:     (about GC identifiers)

Start:
 47,701,340 bp from pter
End:
 47,724,479 bp from pter
Size:
 23,140 bases
Orientation:
 minus strand
RefSeq DNA sequence:
NC_000019.8  NT_011109.15  

Proteins
for CEACAM1

(According to 1UniProtKB, and/or Ensembl, Phosphorylation sites according to 2Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
About This Section

 UniProtKB/Swiss-Prot: CEAM1_HUMAN, P13688 (See protein sequence)
Recommended Name: Carcinoembryonic antigen-related cell adhesion molecule 1 precursor  
Size: 526 amino acids; 57560 Da
Subcellular location: Isoform A: Cell membrane; Single-pass type I membrane protein
Subcellular location: Isoform B: Cell membrane; Single-pass type I membrane protein
Subcellular location: Isoform C: Cell membrane; Single-pass type I membrane protein
Subcellular location: Isoform G: Secreted
Subcellular location: Isoform H: Secreted
Subcellular location: Isoform I: Secreted
PDB structures from and Proteopedia :
2GK2 (3D)    
Secondary accessions: A6NE38 O60430 Q13858 Q15600 Q9UQV9
Alternative splicing: 7 isoforms:  P13688-1   P13688-2   P13688-3   P13688-4   P13688-5   P13688-6   P13688-7   

Post-translational modifications:

  • View phosphorylation sites using PhosphoSite2


    • REFSEQ proteins (2 alternative transcripts): 
    NP_001020083.1  NP_001703.2  


    ENSEMBL proteins: 
    ENSP00000374317 ENSP00000325946 ENSP00000244291 ENSP00000351165 ENSP00000161559 ENSP00000312184 
    ENSP00000367304 ENSP00000341688 ENSP00000384709 ENSP00000384083 ENSP00000367037 ENSP00000381600 
    ENSP00000384843 


    Human Recombinant Proteins 
    Browse Drug Discovery Central at Invitrogen for human recombinant proteins
    Millipore Purified and/or Recombinant CEACAM1 Protein
    Browse Human Recombinant Proteins at Sigma-Aldrich  
    R&D Systems Recombinant & Natural Proteins for CEACAM1 (CEACAM-1/CD66a)
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Recombinant Proteins from Abcam (pan CEACAM, CD66a + CD66c + CD66d + CD66e, CD66a + CD66c + CD66d, CEACAM1)
    Human Recombinant Proteins from Abnova (CEACAM1)
                    Browse Origene for full length recombinant human proteins expressed in human HEK293 cells 

    4 Gene Ontology (GO) cellular component terms (links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005576 extracellular region IEA--
    GO:0005624 membrane fraction TAS2457922
    GO:0005886 plasma membrane IEA--
    GO:0005887 integral to plasma membrane NAS15687237
    About this table

    Antibodies for CEACAM1: 
    Browse Antibodies Central at Invitrogen
    Millipore Mono- and Polyclonal Antibodies for the study of CEACAM1
    Sigma-Aldrich Antibodies for CEACAM1
    R&D Systems Antibodies for CEACAM1 (CEACAM-1/CD66a)
    Antibodies from Abcam (pan CEACAM, CD66a + CD66c + CD66d + CD66e, CD66a + CD66c + CD66d, CEACAM1), each with their AbpromiseSM
    Monoclonal and Polyclonal Antibodies from Abnova (CEACAM1)
    Novus Biologicals Antibodies for CEACAM1

    Assays for CEACAM1: 
    Browse Invitrogen for biochemical assays
    Browse Kits and Assays available from Millipore
    R&D Systems ELISAs for CEACAM1 (CEACAM-1/CD66a)         (see all)
    Browse biochemical assays available from Enzo Life Sciences

    Protein Domains/
    Families
    for CEACAM1

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    5/6 InterPro domains/families (see all 6 ):
     IPR003598 Ig_sub2
     IPR013783 Ig-like_fold
     IPR013106 Ig_V-set
     IPR007110 Ig-like
     IPR003599 Ig_sub


       GeneDecks  CEACAM1 for the domains selected above  
    About GeneDecksing

    Graphical View of Domain Structure for InterPro Entry P13688

    ProtoNet protein and cluster: P13688

    2 Blocks protein families:
    IPB003598 Immunoglobulin C-2 type
    IPB013106 Immunoglobulin V-set


    UniProtKB/Swiss-Prot: CEAM1_HUMAN, P13688
    Similarity: Belongs to the immunoglobulin superfamily. CEA family
    Similarity: Contains 3 Ig-like C2-type (immunoglobulin-like) domains
    Similarity: Contains 1 Ig-like V-type (immunoglobulin-like) domain

    Gene Function
    for CEACAM1

    (According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
    shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
    RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
    About This Section
    Inhib.
    RNA:    		Invitrogen RNAi Products for gene knock-down (CEACAM1)
    Browse for Gene Knock-down Tools from Millipore
    Abnova Chimera RNAi Products for Gene knock-down (CEACAM1)
                   OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 2): NM_001024912

                  Applied Biosystems Silencer® siRNAs for CEACAM1

                  Sigma-Aldrich siRNA and siRNA Panels for CEACAM1  
                         Sigma-Aldrich shRNA Panels and shRNA for CEACAM1  
                         Explore Sigma-Aldrich super-pooled esiRNAs  

    Clones:Invitrogen Clones for CEACAM1
    Browse Clones for the Expression of Recombinant Proteins Available from Millipore
                   OriGene GFP tagged cDNA clones in CMV expression vector (see all 2): NM_001024912
                                     Myc/DDK tagged cDNA clones in CMV expression vector (see all 2): NM_001024912
                                     untagged cDNA clones in CMV expression vector (see all 2): NM_001024912 

    Primers: Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers
                  OriGene genome-wide validated SYBR primer pairs: NM_001712

    Genatlas biochemistry entry for CEACAM1:
    carcinoembryonic antigen-related cell adhesion molecule 1,biliary glycoprotein (see CEA@)

    5 MGI mutant phenotypes (inferred from 5 alleles) (MGI details for Ceacam1):

    digestive/alimentaryhematopoietic systemhomeostasis/metabolismimmune systemtumorigenesis

    1 Gene Ontology (GO) molecular function term (links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003674 molecular_function ND--
    About this table

    Pathways & Interactions
    for CEACAM1

    (Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
    Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to 1UniProtKB, 2MINT, and/or 3STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
    About This Section

    1 Invitrogen iPath™ Online BioAtlas - Pathway for CEACAM1 (Maps provided by GeneGo):
     IFN gamma signaling pathway

       GeneDecks  CEACAM1 for the pathways selected above  
    About GeneDecksing

     Gene Network CentralTM Interacting Genes and Proteins Network for  CEACAM1 


    5/23 Interacting proteins for CEACAM1 (ENSP000003673043 P136882) via UniProtKB, MINT, and/or STRING (see all 23 )
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CLEC4MQ9H2X32MINT-72826 MINT-72821
    SRCENSP000003626593STRING (score=.971)
    PTPN11ENSP000003409443STRING (score=.964)
    CEACAM6ENSP000001997643STRING (score=.962)
    CEACAM8ENSP000002443363STRING (score=.962)
    About this table

    4 Gene Ontology (GO) biological process terms (links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001525 angiogenesis NAS15687237
    GO:0007156 homophilic cell adhesion NAS15687237
    GO:0007229 integrin-mediated signaling pathway NAS15687237
    GO:0016477 cell migration NAS15687237
    About this table

    Drugs & Compounds
    for CEACAM1

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
    About This Section

    Browse drugs & compounds from Enzo Life Sciences
    Browse Small Molecules at Sigma-Aldrich

    Browse Tocris compounds for CEACAM1
    10/12 Novoseek chemical compound relationships for CEACAM1 gene (see all 12 )
    Compound   Score   Articles   PubMed IDs for Articles with Shared Sentences (# sentences)
    matrigel 47.60 14 19285068 (3), 10564638 (3), 15339048 (2), 14522961 (1) (see all 6)
    glycogen 29.17 11 12378338 (1), 10638593 (1), 11384100 (1), 9583890 (1) (see all 7)
    sialic acid 28.75 1 11322763 (1)
    phosphatidylinositol 21.09 8 17071610 (3), 12571236 (2)
    tyrosine 17.84 14 15004154 (2), 17761831 (2), 9867848 (1), 18453603 (1) (see all 8)
    glucose 2.56 1 17393985 (1)
    phenylalanine 0.00 1 11278391 (1)
    oligonucleotide 0.00 1 8631584 (1)
    lipid 0.00 4 15339048 (2), 18081725 (1)
    steroid 0.00 2 9506857 (1), 11964043 (1)
    About this table


    Transcripts
    for CEACAM1

    (GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView,
    non coding RNAs according to RNAdb,
    ESTs according to GeneTide,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from Invitrogen, Millipore, and/or Abnova,
    siRNAs from Applied Biosystems, Sigma-Aldrich,
    shRNA from Sigma-Aldrich, OriGene,
    Tagged/untagged cDNA clones from OriGene,
    Expression Assays from Applied Biosystems)
    About This Section
    Inhib.
    RNA:    		Invitrogen RNAi Products for gene knock-down (CEACAM1)
    Browse for Gene Knock-down Tools from Millipore
    Abnova Chimera RNAi Products for Gene knock-down (CEACAM1)
                   OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 2): NM_001024912

                  Sigma-Aldrich siRNA and siRNA Panels for CEACAM1  
                         Sigma-Aldrich shRNA Panels and shRNA for CEACAM1  
                         Explore Sigma-Aldrich super-pooled esiRNAs  

    Applied Biosystems Silencer® siRNAs: 

    NM_001024912  NM_001712  

    REFSEQ mRNAs for CEACAM1 gene (2 alternative transcripts): 

    NM_001024912.1   NM_001712.3   

    Applied Biosystems TaqMan ® Gene Expression Assays: 

    NM_001024912  NM_001712  

                   OriGene GFP tagged cDNA clones in CMV expression vector (see all 2): NM_001024912
                                     Myc/DDK tagged cDNA clones in CMV expression vector (see all 2): NM_001024912
                                     untagged cDNA clones in CMV expression vector (see all 2): NM_001024912 

    Additional cDNA sequence: 

    AK314211.1 AL833584.1 AY766113.1 BC014473.1 BC024164.1 CR608576.1 D12502.1 D90311.1 
    D90312.1 D90313.1 J03858.1 M69176.1 M72238.1 M76742.1 M76743.1 M76744.1 
    S71326.1 S74647.1 X14831.1 X16354.1 X16356.1 

    21 DOTS entries:

    DT.95146984  DT.100658676  DT.92439258  DT.91978573  DT.121424607  DT.91781689  DT.92439264  DT.100822614 
    DT.121424012  DT.65286356  DT.95293755  DT.40114371  DT.92420006  DT.100822610  DT.86848472  DT.100712890 
    DT.121424282  DT.121424528  DT.75132501  DT.91714653  DT.95147024 

    24/202 AceView cDNA sequences (see all 202 ):

    AA700605 BX396085 AA593076 AI690507 CD612616 X16356 AW450228 M76744 
    AW951862 CB161535 AW027805 BI031918 AI291145 AI738994 BM759588 AI285093 
    AW611749 BI031917 AA337247 BE048590 J03858 AI346459 BU195866 D12097 

    highest scoring ESTs for CEACAM1:

    S71326 X16354 AL709036 AL710589 AL833584 AU099898 BC014473 BC024164 BF904069 BG398599 

    Unigene Cluster for CEACAM1:

    Carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
    Hs.512682  [show with all ESTs]
    Unigene Representative Sequence: NM_001712


    GeneLoc Exon Structure

    13 Ensembl transcripts including schematic representations:
    ENST00000389666  ENST00000351134  ENST00000352591  ENST00000358394  ENST00000161559  ENST00000308072  
    ENST00000378065  ENST00000344391  ENST00000403444  ENST00000403461  ENST00000377806  ENST00000398599  
    ENST00000403136  

    Expression
    for CEACAM1

    (Experimental results according to 1GeneNote and GNF BioGPS,
    probe sets-to-genes annotations according to 2GeneAnnot , 3GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
    Expression Assays from Applied Biosystems )
    About This Section

    CEACAM1 expression in normal and diseased human tissues

     Applied Biosystems TaqMan ® Gene Expression Assays for CEACAM1

    1 / 2 / 3

    12 probe-sets matching CEACAM1 gene


    		Affymetrix
    probe-set    		 Array  GeneAnnot data GeneNote data GeneTide data
    # genes Sensitivity Specificity Correlation Length Gb_Accession Consensus Uniqueness Score Rank
    988_at2, 3 U95-A 1 1.00 1.00 0.97 1.10 X16354 1.00 1.00 1.00 1
    36082_at2, 3 U95-A 1 1.00 1.00 0.91 0.91 S71326 1.00 1.00 1.00 1

    		209498_at2, 3 U133-A 1 1.00 1.00 -- -- X16354 1.00 1.00 1.00 1

    		206576_s_at2, 3 U133-A 1 1.00 1.00 -- -- NM_001712 0.60 1.00 0.82 1

    		210610_at2, 3 U133-A 1 1.00 1.00 -- -- M69176 0.80 1.00 0.91 1

    		211889_x_at2, 3 U133-A 3 1.00 0.94 -- -- D12502 0.80 1.00 0.91 1

    		211883_x_at2, 3 U133-A 6 1.00 0.72 -- -- M76742 0.80 1.00 0.91 1

    		209498_at2 U133Plus2 1 1.00 1.00 -- -- -- -- -- -- --

    		206576_s_at2 U133Plus2 1 1.00 1.00 -- -- -- -- -- -- --

    		210610_at2 U133Plus2 1 1.00 1.00 -- -- -- -- -- -- --

    		211889_x_at2 U133Plus2 3 1.00 0.94 -- -- -- -- -- -- --

    		211883_x_at2 U133Plus2 6 1.00 0.72 -- -- -- -- -- -- --
    GeneDecks  CEACAM1 for binary patterns associated with the probe-sets selected above  
    About GeneDecksing
    About this table    
    Data from (Publications) and GNF BioGPS
        About these images
    About these images

    CGAP SAGE TAG: --

    SOURCE GeneReport for Unigene cluster: Hs.512682

    Expression variation in blood from EXPOLDB for CEACAM1

    Orthologs
    for CEACAM1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD and/or 5MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
    About This Section
    Orthologs for CEACAM1 gene from 2 species
    Organism Gene Locus Description Human
    Similarity    		 NCBI accessions
    mouse
    (Mus musculus)    		 Ceacam15 7 (5.50 cM) carcinoembryonic antigen-related cell adhesion molecule more   -- X84054 
    zebrafish
    (Danio rerio)    		 ceacam11   -- carcinoembryonic antigen-related cell adhesion molecule more 44.97(n)
    34.59(a)    		 114465  NM_001113794.1  NP_001107266.1 
    About this table        Species with no ortholog for CEACAM1

    ENSEMBL Gene Tree for CEACAM1

    Paralogs
    for CEACAM1

    (Paralogs according to 1HomoloGene
    and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
    About This Section

    Paralogs for CEACAM1 gene
    CEACAM61 2  CEACAM51 2  PSG52  PSG92  PSG82  PSG62  PSG112  CEACAM82  
    CEACAM72  PSG32  PSG22  PSG72  PSG12  

    SNPs/Variants
    for CEACAM1

    (According to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
    About This Section


    10/131 NCBI SNPs in CEACAM1 are shown (see all 131 )
    (Click for Applied Biosystems TaqMan ® Genotyping Assay)  (see all 43)
    ABGenomic DataTranscription DataAllele Frequencies
    SNP IDValidChr 19 posSequenceRecsAA
    Chg    		TypeMoreRecsAllele
    freq    		PopTotal
    sample    		More
    ------------
    rs81032851,2
    		A,C,F,H47724464(+) TCCACT/CCTCTG 2 -- ut51 ese312Minor allele frequency- C:0.18NA MN EA EU WA NS 1122
    rs81109041,2
    		A,C,F,H47723209(+) CTATTG/ACATAT 2 V/A mis16Minor allele frequency- A:0.38EU EA WA NS 512
    rs116663501,2
    		A,C,F,H47705203(+) GTAGAA/GTAAGT 2 Y/Y syn1 ut3113Minor allele frequency- G:0.14EU EA WA NA NS 1076
    rs81055251,2
    		A,C,F,H47724706(+) GTGTCC/TTGGCT 2 -- ng3113Minor allele frequency- T:0.14NA EU EA WA NS 1068
    rs81025191,2
    		A,C,F,H47724401(+) GTGGAG/AGAGAG 2 -- ut5115Minor allele frequency- A:0.18NA MN EA EU WA NS 1390
    rs104135281,2
    		C,F,H47725442(+) GAGGGC/GAAGAC 2 -- ng316Minor allele frequency- G:0.01EU EA WA NS 500
    rs116716491,2
    		C,H47725470(+) CAAGGG/TCTGCC 2 -- ng314Minor allele frequency- T:0.00EU EA WA 412
    --
    rs81111711,2
    		C,F47723354(+) GAGCTG/TGGCAG 2 Q/K mis12Minor allele frequency- T:0.24NS 92
    --
    rs81114681,2
    		C,F47723088(+) ATGACT/GTGTAG 2 H/Q mis1 ese32Minor allele frequency- G:0.23NS 94
    --
    rs413998451,2
    		F47724447(-) CAGAGG/CTGACA 2 -- ut512Minor allele frequency- C:0.02NS 92
    About this table

    HapMap Linkage Disequilibrium images for CEACAM1 (up to first 250kb)

    Disorders & Mutations
    for CEACAM1

    (in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
    About This Section

    		 OMIM: 109770

    UniProtKB/Swiss-Prot: CEAM1_HUMAN, P13688
  • Loss or reduced expression is a major event in colorectal carcinogenesis
  • Increased serum levels of BGP-1 are found in individuals suffering from hepatic disorders

    • 10/48 Novoseek disease relationships for CEACAM1 gene (see all 48 )

    Disease   Score   Articles   PubMed IDs for Articles with Shared Sentences (# sentences)
    endometrial neoplasia 55.14 1 16633066 (1)
    colon carcinoma 48.92 2 1815506 (1), 9028835 (1)
    carcinoma 46.47 63 12469186 (7), 11480789 (4), 11384100 (3), 16332726 (3) (see all 20)
    colon tumor 46.31 4 18927117 (1), 11278391 (1), 18507857 (1), 8402684 (1)
    gastrointestinal carcinoma 43.46 1 8188529 (1)
    tumors 43.07 113 17057731 (8), 12122002 (5), 15568039 (5), 15952183 (5) (see all 50)
    colorectal carcinoma 42.15 13 10638593 (5), 10374690 (2), 7504281 (1), 17057731 (1) (see all 6)
    colon cancer 36.26 11 9858884 (2), 15568039 (2), 9028835 (1), 18278069 (1) (see all 6)
    adenoma 36.08 12 10638593 (2), 10374690 (2), 15476270 (2), 9858884 (1) (see all 7)
    endometrial carcinoma 32.26 7 16332726 (3), 16633066 (2), 7690349 (1)
    About this table

    Genetic Association Database: CEACAM1
    Human Genome Epidemiology Navigator: CEACAM1 (2 documents)

    Medical News
    for CEACAM1

    (Possibly Related Articles in Doctor's Guide)
    About This Section

    		   --

    Publications
    for CEACAM1

    (in PubMed. Associations of this gene to articles via 1Novoseek, 2HGNC, 3Entrez Gene, 4UniProtKB/Swiss-Prot, 5UniProtKB/TrEMBL, 6GAD, and/or 7PharmGKB)
    About This Section

    		10/233 PubMed articles for CEACAM1 gene (see all 233 ):

    Search for CEACAM1

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

     ANDOR
    Aliases
    Free Text  
      Query String
    		PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    Genome Databases showing CEACAM1

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
    About This Section
    Entrez Gene: 634 HGNC: 1814 AceView: CEACAM1 Ensembl:ENSG00000079385 euGenes: HUgn634
    ECgene: CEACAM1 H-InvDB: CEACAM1

    Other Databases showing CEACAM1

    (According to HUGE)
    About This Section

    		   --

    Specialized Databases showing CEACAM1

    (According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    ATLAS Chromosomes in Cancer entry for CEACAM1 Genetics and Cytogenetics in Oncology and Haematology

    Licensable Technologies
    for CEACAM1

    (Available from WIS Yeda, Salk, Tufts)
    About This Section

    		  --

    Services
    for CEACAM1

    (Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
    Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
    Enzo Life Sciences, and/or Tocris Bioscience)
    About This Section



    Products for CEACAM1:
     TaqMan ® Gene Expression Assays
     TaqMan ® Genotyping Assays
    		  Free SNP selection tool



      Invitrogen iPath Pathways  Invitrogen BLOCK-iT™ RNAi
      Invitrogen Antibodies  Invitrogen Assays
      Invitrogen Clones  Invitrogen Q-PCR Products
      Invitrogen Human Recombinant Kinases  Invitrogen Custom Antibody and Peptide Service
      Invitrogen Proteins / Assays / Screening Services  Search Invitrogen catalog for CEACAM1-related products

     Millipore Custom Antibody & Bulk Services
     Millipore Preclinical / Clinical Development Services
     Millipore Immunoassay Services
     Millipore Target Screening & Profiling Services


     Predesigned and custom siRNAs for CEACAM1 Antibodies for CEACAM1
     Explore super-pooled esiRNAs Browse proteins at Sigma-Aldrich
     Lentivirus-delivered shRNAs for CEACAM1 Browse small molecules at Sigma-Aldrich
     "Your Favorite Gene" Pathwaysfeedback


      
     Antibodies   Primer Pairs  
     Cell Culture Products   ELISAs  
     Flow Cytometry Kits   Protease Activity Assays & Reagents  
     Cell Selection/Detection Kits & Reagents   ELISA/Assay Development Kits & Reagents  
     Multiplex/Array Assay Kits & Reagents   ELISpot Kits & Development Modules  
     Recombinant & Natural Proteins  

     Recombinant Proteins (CEACAM1)
     Antibodies (CEACAM1)
     Chimera RNAi (CEACAM1)
     Custom Service for Mouse Mab
     Custom Service for Rabbit Pab from Full-length Protein
      
     Search for Antibodies & Assays

     Recombinant Proteins
    (pan CEACAM, CD66a + CD66c + CD66d + CD66e, CD66a + CD66c + CD66d, CEACAM1)
     Antibodies (pan CEACAM, CD66a + CD66c + CD66d + CD66e, CD66a + CD66c + CD66d, CEACAM1)
     Search OriGene for CEACAM1
     Search Tocris compounds for CEACAM1




     Search www.enzolifesicences.com for proteins, assays, substrates, inhibitors & antibodies
     Antibodies for CEACAM1

    GeneCards Homepage    -    Last full update: 2 Jul 2009        Incremental update: 13 Oct 2009

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