Aliases for BEX1 Gene
External Ids for BEX1 Gene
GeneCards Summary for BEX1 Gene
BEX1 (Brain Expressed, X-Linked 1) is a Protein Coding gene. Diseases associated with BEX1 include ischemic optic neuropathy. Among its related pathways are p75(NTR)-mediated signaling. GO annotations related to this gene include RNA polymerase II activating transcription factor binding. An important paralog of this gene is NGFRAP1.
UniProtKB/Swiss-Prot for BEX1 Gene
Signaling adapter molecule involved in p75NTR/NGFR signaling. Plays a role in cell cycle progression and neuronal differentiation. Inhibits neuronal differentiation in response to nerve growth factor (NGF). May act as a link between the cell cycle and neurotrophic factor signaling, possibly by functioning as an upstream modulator of receptor signaling, coordinating biological responses to external signals with internal cellular states (By similarity).