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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

BEST2 Gene

protein-coding   GIFtS: 51
GCID: GC19P012864

Bestrophin 2

(Previous name: vitelliform macular dystrophy 2-like 1)
(Previous symbol: VMD2L1)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Bestrophin 21 2
VMD2L11 2 3 5
Vitelliform Macular Dystrophy 2-Like 11 2
Vitelliform Macular Dystrophy 2-Like Protein 12 3
bestrophin-22
VMD2-Like Gene 12

External Ids:    HGNC: 171071   Entrez Gene: 548312   Ensembl: ENSG000000399877   OMIM: 6073355   UniProtKB: Q8NFU13   

Export aliases for BEST2 gene to outside databases

Previous GC identifers: GC19P012725 GC19P012436


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for BEST2 Gene:
This gene is a member of the bestrophin gene family of anion channels. Bestrophin genes share a similar gene
structure with highly conserved exon-intron boundaries, but with distinct 3' ends. Bestrophins are transmembrane
proteins that contain a homologous region rich in aromatic residues, including an invariant arg-phe-pro motif.
Mutation in one of the family members (bestrophin 1) is associated with vitelliform macular dystrophy. The
bestrophin 2 gene is mainly expressed in the retinal pigment epithelium and colon. (provided by RefSeq, Jul 2008)

GeneCards Summary for BEST2 Gene: 
BEST2 (bestrophin 2) is a protein-coding gene. Diseases associated with BEST2 include bestrophinopathy, and vitelliform macular dystrophy, and among its related super-pathways are Stimuli-sensing channels and SLC-mediated transmembrane transport. GO annotations related to this gene include chloride channel activity and molecular_function. An important paralog of this gene is BEST4.

UniProtKB/Swiss-Prot: BEST2_HUMAN, Q8NFU1
Function: Forms calcium-sensitive chloride channels. Permeable to bicarbonate

Gene Wiki entry for BEST2 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000019.9  NT_011295.11  NC_018930.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the BEST2 gene promoter:
         Pax-5   Sp1   GCNF   Pax-6   AP-2gamma   Tal-1beta   GCNF-1   ITF-2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidBEST2 promoter sequence
   Search SABiosciences Chromatin IP Primers for BEST2

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat BEST2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19p13.2   Ensembl cytogenetic band:  19p13.2   HGNC cytogenetic band: 19p13.2-p13.12

BEST2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
BEST2 gene location

GeneLoc information about chromosome 19         GeneLoc Exon Structure

GeneLoc location for GC19P012864:  view genomic region     (about GC identifiers)

Start:
12,862,516 bp from pter      End:
12,869,272 bp from pter
Size:
6,757 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: BEST2_HUMAN, Q8NFU1 (See protein sequence)
Recommended Name: Bestrophin-2  
Size: 509 amino acids; 57139 Da
Subcellular location: Cell membrane; Multi-pass membrane protein
Sequence caution: Sequence=BAA90970.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Secondary accessions: Q53YQ8 Q9NXP0

Explore the universe of human proteins at neXtProt for BEST2: NX_Q8NFU1

Explore proteomics data for BEST2 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q8NFU1

  • BEST2 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    BEST2 Protein Expression
    REFSEQ proteins: NP_060152.2  
    ENSEMBL proteins: 
     ENSP00000448310   ENSP00000447203   ENSP00000449403   ENSP00000042931  
    Reactome Protein details: Q8NFU1
    Human Recombinant Protein Products for BEST2: 
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    Novus Biologicals BEST2 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for BEST2 

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005886plasma membrane IEA--
    GO:0005929cilium ISS--
    GO:0034707chloride channel complex IEA--

    BEST2 for ontologies           About GeneDecksing



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    Cloud-Clone Corp. CLIAs for BEST2


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    BEST: Ion channels / Chloride channels : Calcium activated : Bestrophins

    2 InterPro protein domains:
     IPR021134 Bestrophin/UPF0187
     IPR000615 Bestrophin

    Graphical View of Domain Structure for InterPro Entry Q8NFU1

    ProtoNet protein and cluster: Q8NFU1

    1 Blocks protein domain: IPB000615 Putative membrane protein

    UniProtKB/Swiss-Prot: BEST2_HUMAN, Q8NFU1
    Similarity: Belongs to the bestrophin family


    BEST2 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: BEST2_HUMAN, Q8NFU1
    Function: Forms calcium-sensitive chloride channels. Permeable to bicarbonate

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003674molecular_function ND--
    GO:0005254contributes to chloride channel activity ISS--
         
    BEST2 for ontologies           About GeneDecksing


    Phenotypes:
         4 MGI mutant phenotypes (inferred from 1 allele(MGI details for Best2):
     digestive/alimentary  homeostasis/metabolism  taste/olfaction  vision/eye 

    BEST2 for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for BEST2 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for BEST2

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for BEST2 
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    miRNA
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    Inhib. RNA
    Products:
        
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for BEST2


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for BEST2 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Ion channel transport
    Ion channel transport0.49
    Stimuli-sensing channels0.49
    2SLC-mediated transmembrane transport
    Transmembrane transport of small molecules0.50
    3Gastric acid secretion
    Salivary secretion0.34

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    3        Reactome Pathways for BEST2
        Transmembrane transport of small molecules
    Stimuli-sensing channels
    Ion channel transport


    1         Kegg Pathway  (Kegg details for BEST2):
        Salivary secretion


    BEST2 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for BEST2

    1 Interacting protein for BEST2 (Q8NFU13) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    DNASE2O001153I2D: score=1 
    About this table

    Gene Ontology (GO): 4 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006821chloride transport ----
    GO:0007608sensory perception of smell ISS--
    GO:0008150biological_process ND--
    GO:0051899membrane depolarization ISS--

    BEST2 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for BEST2

    3 HMDB Compounds for BEST2    About this table
    CompoundSynonyms CAS #PubMed Ids
    CalciumCa (see all 2)7440-70-2--
    ChlorineCl2 (see all 13)16887-00-6--
    Hydrogen carbonateBicarbonate (see all 19)71-52-3--

    Search CenterWatch for drugs/clinical trials and news about BEST2

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for BEST2 gene: 
    NM_017682.2  

    Unigene Cluster for BEST2:

    Bestrophin 2
    Hs.435611  [show with all ESTs]
    Unigene Representative Sequence: NM_017682
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000549706 ENST00000553030(uc002mux.3) ENST00000552539 ENST00000042931

    miRNA
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    Inhib. RNA
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    Additional mRNA sequence: 

    AF440756.1 AK000139.1 AK225232.1 AY515705.1 

    1 DOTS entry:

    DT.435655 

    8 AceView cDNA sequences:

    BX107640 AF440756 CD671941 NM_017682 AK000139 AY515705 AA573517 AA621745 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    BEST2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AGGATGAAAG
    BEST2 Expression
    About this image


    See BEST2 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for BEST2

    SOURCE GeneReport for Unigene cluster: Hs.435611

    UniProtKB/Swiss-Prot: BEST2_HUMAN, Q8NFU1
    Tissue specificity: Mainly confined to the retinal pigment epithelium and colon

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for BEST2

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for BEST2 gene from 6/14 species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Best21 , 5 bestrophin 21, 5 83.04(n)1
    89.94(a)1
      8 (41.46 cM)5
    2129891  NM_001130194.11  NP_001123666.11 
     850072025 
    lizard
    (Anolis carolinensis)
    Reptilia BEST26
    bestrophin 2
    61(a)
    1 ↔ 1
    GL343286.1(870158-891135)
    African clawed frog
    (Xenopus laevis)
    Amphibia MGC536802 similar to vitelliform macular dystrophy 2-like protein more 77.91(n)    BC043854.1 
    zebrafish
    (Danio rerio)
    Actinopterygii best21 bestrophin 2 69.56(n)
    70.6(a)
      567214  XM_690505.1  XP_695597.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta Best11 Bestrophin 1 57.03(n)
    52.43(a)
      53431  NM_001144561.1  NP_001138033.1 
    worm
    (Caenorhabditis elegans)
    Secernentea best-231 Protein BEST-23 48.02(n)
    44.05(a)
      6418643  NM_001129196.1  NP_001122668.1 


    ENSEMBL Gene Tree for BEST2 (if available)
    TreeFam Gene Tree for BEST2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for BEST2 gene
    BEST42  BEST12  BEST32  
    3 SIMAP similar genes for BEST2 using alignment to 2 protein entries:     BEST2_HUMAN (see all proteins):
    BEST3    BEST1    BEST4

    BEST2 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/211 SNPs in BEST2 are shown (see all 211)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 19 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1890496491,2
    --12861460(+) GACAAA/GGTTTT 1 -- us2k10--------
    rs1458403341,2
    --12861552(+) GGAGCA/GTTGGA 1 -- us2k10--------
    rs1153454451,2
    C,F--12861580(+) ATATTG/AGTGTA 1 -- us2k11Minor allele frequency- A:0.04WA 118
    rs1915923471,2
    --12861685(+) GGCCCC/TGCTCT 1 -- us2k10--------
    rs1821784871,2
    C--12861700(+) CTGGGA/TTTGTG 1 -- us2k10--------
    rs1384116581,2
    --12861703(+) GGATTG/TTGTGC 1 -- us2k10--------
    rs1872908011,2
    --12861713(+) CCACCA/GCACTG 1 -- us2k10--------
    rs1176327451,2
    C,F--12861842(+) GGGTGG/AGGTCT 1 -- us2k11Minor allele frequency- A:0.02NA 120
    rs795916791,2
    F--12861854(+) GCACTT/GGGCTG 1 -- us2k11Minor allele frequency- G:0.03EA 120
    rs1416677941,2
    --12861869(+) TGTGGC/GTGTCT 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for BEST2 (12862516 - 12869272 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 3 variations for BEST2:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv911077CNV Loss21882294
    nsv911079CNV Loss21882294
    dgv3733n71CNV Loss21882294

    SABiosciences Cancer Mutation PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 607335    OMIM disorders: --

    5 diseases for BEST2:    About MalaCards
    bestrophinopathy    vitelliform macular dystrophy    retinal degeneration    retinitis
    pancreatitis

    2 diseases from the University of Copenhagen DISEASES database for BEST2:
    Vitelliform macular dystrophy     Bestrophinopathy

    BEST2 for disorders           About GeneDecksing


    Export disorders for BEST2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for BEST2 gene, integrated from 9 sources (see all 20):
    (articles sorted by number of sources associating them with BEST2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Three novel human VMD2-like genes are members of the evolutionary highly conserved RFP-TM family. (PubMed id 12032738)1, 2, 3 Stoehr H.... Weber B.H.F. (2002)
    2. Bestrophin-2 is a candidate calcium-activated chloride channel involved in olfactory transduction. (PubMed id 16912113)1, 3 Pifferi S....Zucchelli S. (2006)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    4. Structure-function analysis of the bestrophin family of anion channels. (PubMed id 12907679)1, 2 Tsunenari T....Nathans J. (2003)
    5. The vitelliform macular dystrophy protein defines a new family of chloride channels. (PubMed id 11904445)1, 2 Sun H.... Nathans J. (2002)
    6. Bestrophin 2 is expressed in human non-pigmented cili ary epithelium but not retinal pigment epithelium. (PubMed id 20157619)1, 9 Zhang Y....Marmorstein A.D. (2010)
    7. Proteomic analysis identifies dysfunction in cellular transport, energy, and protein metabolism in different brain regions of atypical frontotemporal lobar degeneration. (PubMed id 22360420)1 Martins-de-Souza D....Bahn S. (2012)
    8. Bestrophin-2 mediates bicarbonate transport by goblet cells in mouse colon. (PubMed id 20407206)1 Yu K....Hartzell H.C. (2010)
    9. Bestrophin expression and function in the human pancreatic duct cell line, CFPAC-1. (PubMed id 19237432)1 Marsey L.L. and Winpenny J.P. (2009)
    10. Functional roles of bestrophins in ocular epithelia. (PubMed id 19398034)1 Marmorstein A.D....Peachey N.S. (2009)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 54831 HGNC: 17107 AceView: VMD2L1 Ensembl:ENSG00000039987 euGenes: HUgn54831
    ECgene: BEST2 Kegg: 54831 H-InvDB: BEST2

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for BEST2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for BEST2 gene:
    Search GeneIP for patents involving BEST2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
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    About This Section

     
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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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