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Aliases for BEND7 Gene

Aliases for BEND7 Gene

  • BEN Domain Containing 7 2 3
  • C10orf30 3 4
  • Chromosome 10 Open Reading Frame 30 2
  • BEN Domain-Containing Protein 7 3

External Ids for BEND7 Gene

Previous HGNC Symbols for BEND7 Gene

  • C10orf30

Previous GeneCards Identifiers for BEND7 Gene

  • GC10M013521

Summaries for BEND7 Gene

GeneCards Summary for BEND7 Gene

BEND7 (BEN Domain Containing 7) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for BEND7 Gene

Genomics for BEND7 Gene

Regulatory Elements for BEND7 Gene

Genomic Location for BEND7 Gene

Start:
13,438,484 bp from pter
End:
13,528,974 bp from pter
Size:
90,491 bases
Orientation:
Minus strand

Genomic View for BEND7 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for BEND7 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for BEND7 Gene

Proteins for BEND7 Gene

  • Protein details for BEND7 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8N7W2-BEND7_HUMAN
    Recommended name:
    BEN domain-containing protein 7
    Protein Accession:
    Q8N7W2
    Secondary Accessions:
    • Q5SYY7
    • Q5SYY8
    • Q5SYY9
    • Q8N5T7

    Protein attributes for BEND7 Gene

    Size:
    519 amino acids
    Molecular mass:
    57549 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=CAI12222.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305}; Sequence=CAI12223.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305}; Sequence=CAI12660.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305}; Sequence=CAI12661.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};

    Alternative splice isoforms for BEND7 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for BEND7 Gene

Proteomics data for BEND7 Gene at MOPED

Post-translational modifications for BEND7 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for BEND7 Gene

No data available for DME Specific Peptides for BEND7 Gene

Domains for BEND7 Gene

Gene Families for BEND7 Gene

HGNC:
  • BEND :BEN domain containing

Protein Domains for BEND7 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for BEND7 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q8N7W2

UniProtKB/Swiss-Prot:

BEND7_HUMAN :
  • Q8N7W2
Domain:
  • Contains 1 BEN domain.
genes like me logo Genes that share domains with BEND7: view

Function for BEND7 Gene

Gene Ontology (GO) - Molecular Function for BEND7 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 16189514
genes like me logo Genes that share ontologies with BEND7: view

Phenotypes for BEND7 Gene

GenomeRNAi human phenotypes for BEND7:
genes like me logo Genes that share phenotypes with BEND7: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for BEND7

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for BEND7 Gene

Localization for BEND7 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for BEND7 Gene COMPARTMENTS Subcellular localization image for BEND7 gene
Compartment Confidence
nucleus 3
cytosol 2

Gene Ontology (GO) - Cellular Components for BEND7 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0070062 extracellular exosome IDA 19056867
genes like me logo Genes that share ontologies with BEND7: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for BEND7 Gene

Pathways for BEND7 Gene

SuperPathways for BEND7 Gene

No Data Available

Gene Ontology (GO) - Biological Process for BEND7 Gene

None

No data available for Pathways by source for BEND7 Gene

Transcripts for BEND7 Gene

Unigene Clusters for BEND7 Gene

BEN domain containing 7:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for BEND7

Primer Products

  • OriGene qSTAR qPCR primer pairs in human,mouse,rat for BEND7

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for BEND7 Gene

ExUns: 1a · 1b ^ 2 ^ 3a · 3b ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10
SP1: - -
SP2: -

Relevant External Links for BEND7 Gene

GeneLoc Exon Structure for
BEND7
ECgene alternative splicing isoforms for
BEND7

Expression for BEND7 Gene

mRNA expression in normal human tissues for BEND7 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for BEND7 Gene

SOURCE GeneReport for Unigene cluster for BEND7 Gene Hs.498740

genes like me logo Genes that share expressions with BEND7: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for BEND7 Gene

Orthologs for BEND7 Gene

This gene was present in the common ancestor of chordates.

Orthologs for BEND7 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia BEND7 35
  • 99.36 (n)
  • 98.93 (a)
BEND7 36
  • 88 (a)
OneToOne
cow
(Bos Taurus)
Mammalia BEND7 35
  • 87.56 (n)
  • 91.09 (a)
BEND7 36
  • 85 (a)
OneToOne
dog
(Canis familiaris)
Mammalia BEND7 35
  • 88.27 (n)
  • 90.03 (a)
BEND7 36
  • 65 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Bend7 35
  • 85.65 (n)
  • 86.39 (a)
Bend7 16
Bend7 36
  • 72 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia BEND7 36
  • 72 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia BEND7 36
  • 76 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Bend7 35
  • 85.69 (n)
  • 87.81 (a)
chicken
(Gallus gallus)
Aves BEND7 35
  • 77.25 (n)
  • 77.72 (a)
BEND7 36
  • 65 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia BEND7 36
  • 63 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia bend7 35
  • 66.38 (n)
  • 68.19 (a)
zebrafish
(Danio rerio)
Actinopterygii BEND7 36
  • 45 (a)
OneToOne
LOC560711 35
  • 58.58 (n)
  • 58.68 (a)
Species with no ortholog for BEND7:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for BEND7 Gene

ENSEMBL:
Gene Tree for BEND7 (if available)
TreeFam:
Gene Tree for BEND7 (if available)

Paralogs for BEND7 Gene

Pseudogenes.org Pseudogenes for BEND7 Gene

genes like me logo Genes that share paralogs with BEND7: view

No data available for Paralogs for BEND7 Gene

Variants for BEND7 Gene

Sequence variations from dbSNP and Humsavar for BEND7 Gene

SNP ID Clin Chr 10 pos Sequence Context AA Info Type MAF
rs756324 -- 13,484,617(-) TGAGT(A/G)TCAAA intron-variant
rs878017 -- 13,524,204(-) TTCTG(C/T)TGTGT intron-variant
rs878018 -- 13,524,013(-) ATGAA(A/G)GACCA intron-variant
rs946858 -- 13,467,987(-) TCTTC(A/C)CAACA intron-variant
rs946859 -- 13,523,429(+) CCTCT(A/G)CCACA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for BEND7 Gene

Variant ID Type Subtype PubMed ID
nsv831788 CNV Loss 17160897
nsv508568 CNV Loss 20534489
esv2733395 CNV Deletion 23290073
esv7966 CNV Loss 19470904
esv1007603 CNV Deletion 20482838
nsv825252 CNV Gain 20364138

Relevant External Links for BEND7 Gene

HapMap Linkage Disequilibrium report
BEND7

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for BEND7 Gene

Disorders for BEND7 Gene

Relevant External Links for BEND7

Genetic Association Database (GAD)
BEND7
Human Genome Epidemiology (HuGE) Navigator
BEND7
genes like me logo Genes that share disorders with BEND7: view

No data available for UniProtKB/Swiss-Prot for BEND7 Gene

Publications for BEND7 Gene

  1. A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease. (PMID: 16385451) Grupe A. … Goate A. (Am. J. Hum. Genet. 2006) 3 48
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. The DNA sequence and comparative analysis of human chromosome 10. (PMID: 15164054) Deloukas P. … Rogers J. (Nature 2004) 3 4
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  5. Towards a proteome-scale map of the human protein-protein interaction network. (PMID: 16189514) Rual J.F. … Vidal M. (Nature 2005) 3

Products for BEND7 Gene

Sources for BEND7 Gene

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