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Aliases for BEND7 Gene

Aliases for BEND7 Gene

  • BEN Domain Containing 7 2 3 5
  • C10orf30 3 4
  • Chromosome 10 Open Reading Frame 30 2

External Ids for BEND7 Gene

Previous HGNC Symbols for BEND7 Gene

  • C10orf30

Previous GeneCards Identifiers for BEND7 Gene

  • GC10M013521

Summaries for BEND7 Gene

GeneCards Summary for BEND7 Gene

BEND7 (BEN Domain Containing 7) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for BEND7 Gene

Genomics for BEND7 Gene

Regulatory Elements for BEND7 Gene

Enhancers for BEND7 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around BEND7 on UCSC Golden Path with GeneCards custom track

Promoters for BEND7 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around BEND7 on UCSC Golden Path with GeneCards custom track

Genomic Location for BEND7 Gene

13,438,484 bp from pter
13,528,974 bp from pter
90,491 bases
Minus strand

Genomic View for BEND7 Gene

Genes around BEND7 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
BEND7 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for BEND7 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for BEND7 Gene

Proteins for BEND7 Gene

  • Protein details for BEND7 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    BEN domain-containing protein 7
    Protein Accession:
    Secondary Accessions:
    • Q5SYY7
    • Q5SYY8
    • Q5SYY9
    • Q8N5T7

    Protein attributes for BEND7 Gene

    519 amino acids
    Molecular mass:
    57549 Da
    Quaternary structure:
    No Data Available
    • Sequence=CAI12222.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305}; Sequence=CAI12223.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305}; Sequence=CAI12660.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305}; Sequence=CAI12661.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};

    Alternative splice isoforms for BEND7 Gene


neXtProt entry for BEND7 Gene

Proteomics data for BEND7 Gene at MOPED

Post-translational modifications for BEND7 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for BEND7 Gene

No data available for DME Specific Peptides for BEND7 Gene

Domains & Families for BEND7 Gene

Gene Families for BEND7 Gene

Protein Domains for BEND7 Gene


Suggested Antigen Peptide Sequences for BEND7 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Contains 1 BEN domain.
  • Contains 1 BEN domain.
genes like me logo Genes that share domains with BEND7: view

Function for BEND7 Gene

genes like me logo Genes that share phenotypes with BEND7: view

Animal Model Products

Inhibitory RNA Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for BEND7 Gene

Localization for BEND7 Gene

Subcellular locations from

Jensen Localization Image for BEND7 Gene COMPARTMENTS Subcellular localization image for BEND7 gene
Compartment Confidence
extracellular 5
nucleus 4
cytosol 3

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for BEND7 Gene

Pathways & Interactions for BEND7 Gene

SuperPathways for BEND7 Gene

No Data Available

Gene Ontology (GO) - Biological Process for BEND7 Gene


No data available for Pathways by source and SIGNOR curated interactions for BEND7 Gene

Drugs & Compounds for BEND7 Gene

No Compound Related Data Available

Transcripts for BEND7 Gene

Unigene Clusters for BEND7 Gene

BEN domain containing 7:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for BEND7 Gene

ExUns: 1a · 1b ^ 2 ^ 3a · 3b ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10
SP1: - -
SP2: -

Relevant External Links for BEND7 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for BEND7 Gene

mRNA expression in normal human tissues for BEND7 Gene

Protein differential expression in normal tissues from HIPED for BEND7 Gene

This gene is overexpressed in Cervix (50.3) and Heart (6.4).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for BEND7 Gene

SOURCE GeneReport for Unigene cluster for BEND7 Gene Hs.498740

genes like me logo Genes that share expression patterns with BEND7: view

Protein tissue co-expression partners for BEND7 Gene

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for BEND7 Gene

Orthologs for BEND7 Gene

This gene was present in the common ancestor of chordates.

Orthologs for BEND7 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia BEND7 35
  • 87.56 (n)
  • 91.09 (a)
BEND7 36
  • 85 (a)
(Canis familiaris)
Mammalia BEND7 35
  • 88.27 (n)
  • 90.03 (a)
BEND7 36
  • 65 (a)
(Mus musculus)
Mammalia Bend7 35
  • 85.65 (n)
  • 86.39 (a)
Bend7 16
Bend7 36
  • 72 (a)
(Pan troglodytes)
Mammalia BEND7 35
  • 99.36 (n)
  • 98.93 (a)
BEND7 36
  • 88 (a)
(Rattus norvegicus)
Mammalia Bend7 35
  • 85.69 (n)
  • 87.81 (a)
(Monodelphis domestica)
Mammalia BEND7 36
  • 72 (a)
(Ornithorhynchus anatinus)
Mammalia BEND7 36
  • 76 (a)
(Gallus gallus)
Aves BEND7 35
  • 77.25 (n)
  • 77.72 (a)
BEND7 36
  • 65 (a)
(Anolis carolinensis)
Reptilia BEND7 36
  • 63 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia bend7 35
  • 66.38 (n)
  • 68.19 (a)
(Danio rerio)
Actinopterygii LOC560711 35
  • 58.58 (n)
  • 58.68 (a)
BEND7 36
  • 45 (a)
Species with no ortholog for BEND7:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for BEND7 Gene

Gene Tree for BEND7 (if available)
Gene Tree for BEND7 (if available)

Paralogs for BEND7 Gene Pseudogenes for BEND7 Gene

genes like me logo Genes that share paralogs with BEND7: view

No data available for Paralogs for BEND7 Gene

Variants for BEND7 Gene

Sequence variations from dbSNP and Humsavar for BEND7 Gene

SNP ID Clin Chr 10 pos Sequence Context AA Info Type
VAR_035501 A breast cancer sample
rs12247033 - 13,480,940(+) TCCGG(C/T)TGTCA intron-variant, nc-transcript-variant, reference, missense
rs1538791 -- 13,487,240(-) TTGCA(A/G/T)CTGCA intron-variant
rs1556990 -- 13,508,822(-) TTTGT(C/T)TCCTG intron-variant
rs1556991 -- 13,506,332(-) AGCCA(A/G)GTTCT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for BEND7 Gene

Variant ID Type Subtype PubMed ID
nsv831788 CNV Loss 17160897
nsv508568 CNV Loss 20534489
esv2733395 CNV Deletion 23290073
esv7966 CNV Loss 19470904
esv1007603 CNV Deletion 20482838
nsv825252 CNV Gain 20364138

Variation tolerance for BEND7 Gene

Residual Variation Intolerance Score: 74.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 4.20; 61.98% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for BEND7 Gene

Disorders for BEND7 Gene

Relevant External Links for BEND7

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator
Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for BEND7 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for BEND7 Gene

Publications for BEND7 Gene

  1. A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease. (PMID: 16385451) Grupe A. … Goate A. (Am. J. Hum. Genet. 2006) 3 48 67
  2. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3
  3. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3
  4. Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. (PMID: 23382691) Lauc G. … Rudan I. (PLoS Genet. 2013) 3
  5. Next-generation sequencing to generate interactome datasets. (PMID: 21516116) Yu H. … Vidal M. (Nat. Methods 2011) 3

Products for BEND7 Gene

Sources for BEND7 Gene