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Aliases for BEND4 Gene

Aliases for BEND4 Gene

  • BEN Domain Containing 4 2 3
  • Coiled-Coil Domain-Containing Protein 4 3 4
  • Coiled-Coil Domain Containing 4 2 3
  • CCDC4 3 4
  • BEN Domain-Containing Protein 4 3

External Ids for BEND4 Gene

Previous Symbols for BEND4 Gene

  • CCDC4

Summaries for BEND4 Gene

GeneCards Summary for BEND4 Gene

BEND4 (BEN Domain Containing 4) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for BEND4 Gene

Genomics for BEND4 Gene

Genomic Location for BEND4 Gene

Start:
42,110,853 bp from pter
End:
42,152,878 bp from pter
Size:
42,026 bases
Orientation:
Minus strand

Genomic View for BEND4 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for BEND4 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for BEND4 Gene

Regulatory Elements for BEND4 Gene

Proteins for BEND4 Gene

  • Protein details for BEND4 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6ZU67-BEND4_HUMAN
    Recommended name:
    BEN domain-containing protein 4
    Protein Accession:
    Q6ZU67
    Secondary Accessions:
    • A1A5D6
    • A1A5D7
    • C9JQZ5
    • Q58A26
    • Q58A27

    Protein attributes for BEND4 Gene

    Size:
    534 amino acids
    Molecular mass:
    58375 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAI28593.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=AAI28594.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=BAD93191.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=BAD93192.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};

    Alternative splice isoforms for BEND4 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for BEND4 Gene

Proteomics data for BEND4 Gene at MOPED

Post-translational modifications for BEND4 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for BEND4 Gene

No data available for DME Specific Peptides for BEND4 Gene

Domains for BEND4 Gene

Gene Families for BEND4 Gene

HGNC:
  • BEND :BEN domain containing

Protein Domains for BEND4 Gene

InterPro:
ProtoNet:

UniProtKB/Swiss-Prot:

BEND4_HUMAN
Domain:
  • Contains 1 BEN domain.:
    • Q6ZU67
genes like me logo Genes that share domains with BEND4: view

Function for BEND4 Gene

Phenotypes for BEND4 Gene

genes like me logo Genes that share phenotypes with BEND4: view

miRNA for BEND4 Gene

miRTarBase miRNAs that target BEND4

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , Transcription Factor Targeting and HOMER Transcription for BEND4 Gene

Localization for BEND4 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for BEND4 Gene COMPARTMENTS Subcellular localization image for BEND4 gene
Compartment Confidence
nucleus 3
cytosol 2

No data available for Gene Ontology (GO) - Cellular Components for BEND4 Gene

Pathways for BEND4 Gene

SuperPathways for BEND4 Gene

No Data Available

Interacting Proteins for BEND4 Gene

Gene Ontology (GO) - Biological Process for BEND4 Gene

None

No data available for Pathways by source for BEND4 Gene

Transcripts for BEND4 Gene

mRNA/cDNA for BEND4 Gene

(2) REFSEQ mRNAs :
(6) Additional mRNA sequences :
(7) Selected AceView cDNA sequences:
(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for BEND4 Gene

BEN domain containing 4:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for BEND4 Gene

No ASD Table

Relevant External Links for BEND4 Gene

GeneLoc Exon Structure for
BEND4
ECgene alternative splicing isoforms for
BEND4

Expression for BEND4 Gene

mRNA expression in normal human tissues for BEND4 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for BEND4 Gene

This gene is overexpressed in Testis (10.2).

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for BEND4 Gene

SOURCE GeneReport for Unigene cluster for BEND4 Gene Hs.120591

genes like me logo Genes that share expressions with BEND4: view

Orthologs for BEND4 Gene

This gene was present in the common ancestor of chordates.

Orthologs for BEND4 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia BEND4 36
  • 98.56 (n)
  • 98.31 (a)
BEND4 37
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia BEND4 36
  • 90.58 (n)
  • 93.22 (a)
BEND4 37
  • 93 (a)
OneToOne
dog
(Canis familiaris)
Mammalia BEND4 36
  • 92.34 (n)
  • 95.72 (a)
BEND4 37
  • 90 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Bend4 36
  • 87.23 (n)
  • 89.81 (a)
Bend4 16
Bend4 37
  • 88 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia BEND4 37
  • 83 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia BEND4 37
  • 74 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Bend4 36
  • 88.47 (n)
  • 95.64 (a)
chicken
(Gallus gallus)
Aves BEND4 36
  • 84.49 (n)
  • 90.43 (a)
BEND4 37
  • 83 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia BEND4 37
  • 74 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia bend4 36
  • 74.83 (n)
  • 75.9 (a)
zebrafish
(Danio rerio)
Actinopterygii BEND4 37
  • 58 (a)
OneToOne
LOC566937 36
  • 65.38 (n)
  • 69.51 (a)
Species with no ortholog for BEND4:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for BEND4 Gene

ENSEMBL:
Gene Tree for BEND4 (if available)
TreeFam:
Gene Tree for BEND4 (if available)

Paralogs for BEND4 Gene

No data available for Paralogs for BEND4 Gene

Variants for BEND4 Gene

Sequence variations from dbSNP and Humsavar for BEND4 Gene

SNP ID Clin Chr 04 pos Sequence Context AA Info Type MAF
rs13756 -- 42,111,224(-) ATAAA(A/G)CTACA utr-variant-3-prime
rs2343617 -- 42,119,395(+) TCTAG(C/G)TCTGT intron-variant
rs2880666 -- 42,118,492(+) GAGCT(A/G)GAGAC intron-variant
rs3810840 -- 42,119,757(-) TGGAG(C/T)ATAGG intron-variant
rs3923787 -- 42,151,242(-) CCTTT(C/T)TCCTT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for BEND4 Gene

Variant ID Type Subtype PubMed ID
dgv5532n71 CNV Loss 21882294
nsv527340 CNV Loss 19592680
nsv523585 CNV Gain 19592680
nsv822545 CNV Gain 20364138
dgv870n67 CNV Gain 20364138

Relevant External Links for BEND4 Gene

HapMap Linkage Disequilibrium report
BEND4

Disorders for BEND4 Gene

Relevant External Links for BEND4

Genetic Association Database (GAD)
BEND4
genes like me logo Genes that share disorders with BEND4: view

No data available for UniProtKB/Swiss-Prot for BEND4 Gene

Publications for BEND4 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4
  3. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PMID: 15815621) Hillier L.W. … Wilson R.K. (Nature 2005) 4
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for BEND4 Gene

Sources for BEND4 Gene

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