External Ids for BEND3 Gene
Previous HGNC Symbols for BEND3 Gene
Previous GeneCards Identifiers for BEND3 Gene
GeneCards Summary for BEND3 Gene
BEND3 (BEN Domain Containing 3) is a Protein Coding gene.
UniProtKB/Swiss-Prot for BEND3 Gene
Transcriptional repressor which associates with the NoRC (nucleolar remodeling complex) complex and plays a key role in repressing rDNA transcription. The sumoylated form modulates the stability of the NoRC complex component BAZ2A/TIP5 by controlling its USP21-mediated deubiquitination (PubMed:21914818, PubMed:26100909). Binds to unmethylated major satellite DNA and is involved in the recruitment of the Polycomb repressive complex 2 (PRC2) to major satellites (By similarity).