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Aliases for BEND3 Gene

Aliases for BEND3 Gene

  • BEN Domain Containing 3 2 3
  • KIAA1553 2 3 4
  • BEN Domain-Containing Protein 3 3

External Ids for BEND3 Gene

Previous HGNC Symbols for BEND3 Gene

  • KIAA1553

Previous GeneCards Identifiers for BEND3 Gene

  • GC06M107494
  • GC06M107386
  • GC06M104957

Summaries for BEND3 Gene

GeneCards Summary for BEND3 Gene

BEND3 (BEN Domain Containing 3) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for BEND3 Gene

Genomics for BEND3 Gene

Regulatory Elements for BEND3 Gene

Genomic Location for BEND3 Gene

Start:
107,065,181 bp from pter
End:
107,115,269 bp from pter
Size:
50,089 bases
Orientation:
Minus strand

Genomic View for BEND3 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for BEND3 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for BEND3 Gene

Proteins for BEND3 Gene

  • Protein details for BEND3 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q5T5X7-BEND3_HUMAN
    Recommended name:
    BEN domain-containing protein 3
    Protein Accession:
    Q5T5X7
    Secondary Accessions:
    • A2RRH2
    • Q9HCL9

    Protein attributes for BEND3 Gene

    Size:
    828 amino acids
    Molecular mass:
    94475 Da
    Quaternary structure:
    No Data Available

neXtProt entry for BEND3 Gene

Proteomics data for BEND3 Gene at MOPED

Post-translational modifications for BEND3 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for BEND3 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for BEND3 Gene

Domains for BEND3 Gene

Gene Families for BEND3 Gene

HGNC:
  • BEND :BEN domain containing

Protein Domains for BEND3 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for BEND3 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q5T5X7

UniProtKB/Swiss-Prot:

BEND3_HUMAN :
  • Q5T5X7
Domain:
  • Contains 4 BEN domains.
genes like me logo Genes that share domains with BEND3: view

Function for BEND3 Gene

Gene Ontology (GO) - Molecular Function for BEND3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with BEND3: view

Phenotypes for BEND3 Gene

genes like me logo Genes that share phenotypes with BEND3: view

miRNA for BEND3 Gene

miRTarBase miRNAs that target BEND3

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for BEND3 Gene

Localization for BEND3 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for BEND3 Gene COMPARTMENTS Subcellular localization image for BEND3 gene
Compartment Confidence
nucleus 3
cytosol 2
golgi apparatus 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for BEND3 Gene

Pathways for BEND3 Gene

SuperPathways for BEND3 Gene

No Data Available

Gene Ontology (GO) - Biological Process for BEND3 Gene

None

No data available for Pathways by source for BEND3 Gene

Transcripts for BEND3 Gene

mRNA/cDNA for BEND3 Gene

Unigene Clusters for BEND3 Gene

BEN domain containing 3:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for BEND3 Gene

No ASD Table

Relevant External Links for BEND3 Gene

GeneLoc Exon Structure for
BEND3
ECgene alternative splicing isoforms for
BEND3

Expression for BEND3 Gene

mRNA expression in normal human tissues for BEND3 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for BEND3 Gene

SOURCE GeneReport for Unigene cluster for BEND3 Gene Hs.418045

genes like me logo Genes that share expressions with BEND3: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for BEND3 Gene

Orthologs for BEND3 Gene

This gene was present in the common ancestor of chordates.

Orthologs for BEND3 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia BEND3 35
  • 99.36 (n)
  • 99.64 (a)
BEND3 36
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia BEND3 35
  • 89.86 (n)
  • 93.84 (a)
BEND3 36
  • 94 (a)
OneToOne
dog
(Canis familiaris)
Mammalia BEND3 35
  • 90.74 (n)
  • 93.72 (a)
BEND3 36
  • 93 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Bend3 35
  • 86.34 (n)
  • 91.15 (a)
Bend3 16
Bend3 36
  • 91 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia BEND3 36
  • 83 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Bend3 35
  • 87.21 (n)
  • 92.01 (a)
chicken
(Gallus gallus)
Aves BEND3 35
  • 71.11 (n)
  • 77.72 (a)
BEND3 36
  • 76 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia BEND3 36
  • 66 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia bend3 35
  • 63.75 (n)
  • 69.38 (a)
zebrafish
(Danio rerio)
Actinopterygii bend3 35
  • 63.07 (n)
  • 62.63 (a)
bend3 36
  • 54 (a)
OneToOne
Species with no ortholog for BEND3:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for BEND3 Gene

ENSEMBL:
Gene Tree for BEND3 (if available)
TreeFam:
Gene Tree for BEND3 (if available)

Paralogs for BEND3 Gene

Pseudogenes.org Pseudogenes for BEND3 Gene

genes like me logo Genes that share paralogs with BEND3: view

No data available for Paralogs for BEND3 Gene

Variants for BEND3 Gene

Sequence variations from dbSNP and Humsavar for BEND3 Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type MAF
rs311208 -- 107,108,854(-) cactc(C/T)atcct intron-variant
rs311209 -- 107,108,234(-) CAGGC(A/G)CGCGG intron-variant, upstream-variant-2KB
rs311210 -- 107,107,404(-) GTAAC(A/T)TTGAG intron-variant, upstream-variant-2KB
rs311211 -- 107,106,892(-) ggtgg(C/G/T)ttgca intron-variant, upstream-variant-2KB
rs311212 -- 107,106,749(-) cacct(A/G)tagtc intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for BEND3 Gene

Variant ID Type Subtype PubMed ID
esv2732546 CNV Deletion 23290073
dgv87n68 CNV Loss 17160897
esv2732547 CNV Deletion 23290073
esv2732548 CNV Deletion 23290073
nsv521601 CNV Loss 19592680
esv1657137 CNV Deletion 17803354
dgv1063n67 CNV Gain 20364138
esv27390 CNV Loss 19812545

Relevant External Links for BEND3 Gene

HapMap Linkage Disequilibrium report
BEND3

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for BEND3 Gene

Disorders for BEND3 Gene

Relevant External Links for BEND3

Human Genome Epidemiology (HuGE) Navigator
BEND3
genes like me logo Genes that share disorders with BEND3: view

No data available for UniProtKB/Swiss-Prot for BEND3 Gene

Publications for BEND3 Gene

  1. Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PMID: 10997877) Nagase T. … Ohara O. (DNA Res. 2000) 3 4
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  3. Distinct and overlapping sets of SUMO-1 and SUMO-2 target proteins revealed by quantitative proteomics. (PMID: 17000644) Vertegaal A.C. … Lamond A.I. (Mol. Cell Proteomics 2006) 3
  4. System-wide changes to SUMO modifications in response to heat shock. (PMID: 19471022) Golebiowski F. … Hay R.T. (Sci Signal 2009) 3
  5. Defining the human deubiquitinating enzyme interaction landscape. (PMID: 19615732) Sowa M.E. … Harper J.W. (Cell 2009) 3

Products for BEND3 Gene

Sources for BEND3 Gene

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