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Aliases for BDNF-AS Gene

Subcategory (RNA class) for BDNF-AS Gene

non-coding RNA

Quality Score for this RNA gene is

13

Aliases for BDNF-AS Gene

  • BDNF Antisense RNA 2 3 5
  • BDNF Antisense RNA 1 (Non-Protein Coding) 2 3
  • BDNF Opposite Strand (Non-Protein Coding) 2 3
  • BDNF Antisense RNA (Non-Protein Coding) 2 3
  • Brain-Derived Neurotrophic Factor Opposite Strand 3
  • Non-Protein Coding RNA 49 2
  • NCRNA00049 3
  • ANTI-BDNF 3
  • BDNF-AS1 3
  • BDNFAS 3
  • BDNFOS 3
  • BDNF 3

External Ids for BDNF-AS Gene

Previous HGNC Symbols for BDNF-AS Gene

  • BDNFOS

Summaries for BDNF-AS Gene

GeneCards Summary for BDNF-AS Gene

BDNF-AS (BDNF Antisense RNA) is an RNA Gene, and is affiliated with the non-coding RNA class. Diseases associated with BDNF-AS include Substance Abuse.

Additional gene information for BDNF-AS Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for BDNF-AS Gene

Genomics for BDNF-AS Gene

GeneHancer (GH) Regulatory Elements for BDNF-AS Gene

Promoters and enhancers for BDNF-AS Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH11I027505 Promoter/Enhancer 2 EPDnew Ensembl ENCODE 550.8 -0.2 -166 2.5 PKNOX1 SMAD1 ARNT ARID4B SIN3A DMAP1 ZNF2 YY1 SLC30A9 POLR2B LIN7C BDNF-AS GC11P027508 GC11P027483
GH11I027460 Enhancer 1.3 FANTOM5 Ensembl ENCODE 10.4 -46.3 -46341 1.8 ELF3 FOXA2 ZFP64 ARID4B DMAP1 DNMT3B ZSCAN9 RAD21 RARA CREM LIN7C BDNF-AS GC11P027468 LGR4 GC11P027442
GH11I027447 Enhancer 0.9 ENCODE dbSUPER 14.1 -58.8 -58788 1.7 MEIS2 ZNF639 STAT1 PKNOX1 ZNF362 RFX1 JUN CEBPB ZNF384 FEZF1 BDNF-AS LIN7C LGR4 LOC105376671 GC11P027442 GC11P027468
GH11I027463 Promoter/Enhancer 2.4 EPDnew Ensembl ENCODE dbSUPER 4.4 -38.4 -38395 10.8 PKNOX1 FOXA2 ARNT ARID4B SIN3A ZNF48 YY1 GTF3C2 ZNF766 GLIS2 GC11P027468 LGR4 LIN7C BDNF-AS LOC105376671
GH11I027443 Enhancer 0.9 ENCODE dbSUPER 10.2 -62.2 -62203 2.5 MEIS2 PKNOX1 USF1 ARID4B MZF1 SIN3A MNT SP1 PRDM6 POLR2A GC11P027442 LIN7C LOC105376671 LGR4 BDNF-AS GC11P027468
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around BDNF-AS on UCSC Golden Path with GeneCards custom track

Genomic Locations for BDNF-AS Gene

Genomic Locations for BDNF-AS Gene
chr11:27,506,838-27,698,174
(GRCh38/hg38)
Size:
191,337 bases
Orientation:
Plus strand
chr11:27,528,385-27,719,721
(GRCh37/hg19)

Genomic View for BDNF-AS Gene

Genes around BDNF-AS on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
BDNF-AS Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for BDNF-AS Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for BDNF-AS Gene

Proteins for BDNF-AS Gene

Post-translational modifications for BDNF-AS Gene

No Post-translational modifications

No data available for DME Specific Peptides for BDNF-AS Gene

Domains & Families for BDNF-AS Gene

Gene Families for BDNF-AS Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with BDNF-AS: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for BDNF-AS Gene

Function for BDNF-AS Gene

Phenotypes From GWAS Catalog for BDNF-AS Gene

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for BDNF-AS Gene

Localization for BDNF-AS Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for BDNF-AS gene
Compartment Confidence
cytoskeleton 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for BDNF-AS Gene

Pathways & Interactions for BDNF-AS Gene

SuperPathways for BDNF-AS Gene

No Data Available

Interacting Proteins for BDNF-AS Gene

Gene Ontology (GO) - Biological Process for BDNF-AS Gene

None

No data available for Pathways by source and SIGNOR curated interactions for BDNF-AS Gene

Drugs & Compounds for BDNF-AS Gene

(1) Drugs for BDNF-AS Gene - From: PharmGKB

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
antipsychotics Pharma 0
genes like me logo Genes that share compounds with BDNF-AS: view

Transcripts for BDNF-AS Gene

mRNA/cDNA for BDNF-AS Gene

(34) Additional mRNA sequences :
(9) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for BDNF-AS Gene

BDNF antisense RNA:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for BDNF-AS Gene

No ASD Table

Relevant External Links for BDNF-AS Gene

GeneLoc Exon Structure for
BDNF-AS
ECgene alternative splicing isoforms for
BDNF-AS

Expression for BDNF-AS Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for BDNF-AS Gene

mRNA differential expression in normal tissues according to GTEx for BDNF-AS Gene

This gene is overexpressed in Brain - Spinal cord (cervical c-1) (x4.6).

SOURCE GeneReport for Unigene cluster for BDNF-AS Gene:

Hs.675323
genes like me logo Genes that share expression patterns with BDNF-AS: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for BDNF-AS Gene

Orthologs for BDNF-AS Gene

Evolution for BDNF-AS Gene

ENSEMBL:
Gene Tree for BDNF-AS (if available)
TreeFam:
Gene Tree for BDNF-AS (if available)

No data available for Orthologs for BDNF-AS Gene

Paralogs for BDNF-AS Gene

No data available for Paralogs for BDNF-AS Gene

Variants for BDNF-AS Gene

Sequence variations from dbSNP and Humsavar for BDNF-AS Gene

SNP ID Clin Chr 11 pos Variation AA Info Type
rs6265 risk-factor, protective, benign, Memory impairment, susceptibility to, Obsessive-compulsive disorder, protection against, Anorexia nervosa 2, Bulimia nervosa 2, Bipolar affective disorder, susceptibility to, Parkinson disease, not specified 27,658,369(+) C/T non_coding_transcript_variant
rs8192466 pathogenic, Congenital central hypoventilation 27,658,560(+) G/A/T intron_variant
rs2353512 benign, not specified 27,658,115(+) C/T intron_variant
rs1000008594 -- 27,623,536(+) C/T intron_variant
rs1000019582 -- 27,602,719(+) G/T intron_variant

Structural Variations from Database of Genomic Variants (DGV) for BDNF-AS Gene

Variant ID Type Subtype PubMed ID
dgv135e201 CNV deletion 23290073
dgv607n106 CNV deletion 24896259
esv1476336 CNV insertion 17803354
esv1745758 CNV deletion 17803354
esv2064689 CNV deletion 18987734
esv2672678 CNV deletion 23128226
esv2744288 CNV deletion 23290073
esv2744290 CNV deletion 23290073
esv2744292 CNV deletion 23290073
esv2744293 CNV deletion 23290073
esv2744294 CNV deletion 23290073
esv3258052 CNV deletion 24192839
esv3357461 CNV insertion 20981092
esv3454 CNV loss 18987735
esv3547509 CNV deletion 23714750
esv3625772 CNV loss 21293372
esv3625773 CNV loss 21293372
esv5866 CNV loss 19470904
nsv1076609 CNV deletion 25765185
nsv1141919 OTHER inversion 24896259
nsv474533 CNV novel sequence insertion 20440878
nsv819223 CNV gain 19587683
nsv832095 CNV gain 17160897
nsv957875 CNV insertion 24416366
nsv958620 CNV deletion 24416366
nsv971997 CNV duplication 23825009
nsv982998 CNV duplication 23825009

Additional Variant Information for BDNF-AS Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
BDNF-AS

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for BDNF-AS Gene

Disorders for BDNF-AS Gene

MalaCards: The human disease database

(1) MalaCards diseases for BDNF-AS Gene - From: GeneCards

Disorder Aliases PubMed IDs
substance abuse
  • substance-related disorders
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for BDNF-AS

genes like me logo Genes that share disorders with BDNF-AS: view

No data available for UniProtKB/Swiss-Prot and Genatlas for BDNF-AS Gene

Publications for BDNF-AS Gene

  1. Knockdown of long noncoding antisense RNA brain-derived neurotrophic factor attenuates hypoxia/reoxygenation-induced nerve cell apoptosis through the BDNF-TrkB-PI3K/Akt signaling pathway. (PMID: 28777258) Zhong JB … Wu XY (Neuroreport 2017) 2 3 58
  2. Inhibition of natural antisense transcripts in vivo results in gene-specific transcriptional upregulation. (PMID: 22446693) Modarresi F … Wahlestedt C (Nature biotechnology 2012) 2 3 58
  3. Human brain derived neurotrophic factor (BDNF) genes, splicing patterns, and assessments of associations with substance abuse and Parkinson's Disease. (PMID: 15666411) Liu QR … Uhl GR (American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2005) 2 3 58
  4. BDNF Variants May Modulate Long-Term Visual Memory Performance in a Healthy Cohort. (PMID: 28304362) Avgan N … Griffiths LR (International journal of molecular sciences 2017) 3 58
  5. Meta-analysis of genome-wide association studies in East Asian-ancestry populations identifies four new loci for body mass index. (PMID: 24861553) Wen W … Tanaka T (Human molecular genetics 2014) 3 58

Products for BDNF-AS Gene

Sources for BDNF-AS Gene

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