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Breakpoint Cluster Region Pseudogene 3(Previous names: breakpoint cluster region-like 6, breakpoint cluster region-like...)
(Previous symbols: BCR3, BCRL6, BCRL3)
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Aliases
for BCRP3 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
10fRNAdb,
12H-InvDB,
13NCBI,
14NONCODE,
and/or 15RNAdb)
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| Aliases |
|---|
| Breakpoint Cluster Region Pseudogene 31 2 | | BCRL31 2 5 | | BCR31 2 | | BCRL61 2 | | Breakpoint Cluster Region-Like 31 | | Breakpoint Cluster Region-Like 61 |
Export aliases for BCRP3 gene to outside databases |
Summaries
for BCRP3 gene(According to Entrez Gene,
GeneCards,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
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GeneCards Summary for BCRP3 Gene:
BCRP3 (breakpoint cluster region pseudogene 3) is a pseudogene.
|
Genomic Views
for BCRP3 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 75),
Regulatory elements and Epigenetics data according to
QIAGEN, and/or
SwitchGear Genomics)
About This Section
TryGeneCards Plus | RefSeq DNA sequence:- NC_000022.11 NC_018933.2 NT_011520.13
Regulatory elements:
 Search for regulatory transcription factor binding sites for BCRP3
Other transcription factors
Search Chromatin IP Primers for BCRP3
Epigenetics:
| | DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat BCRP3 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 22q11.23 Ensembl cytogenetic band: 22q11.23 HGNC cytogenetic band: 22q11BCRP3 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 22 GeneLoc Exon Structure GeneLoc location for GC22P025030: view genomic region
(about GC identifiers)
Start:
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25,028,882 bp from pter |
End:
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25,049,327 bp from pter |
Size:
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20,446 bases |
Orientation:
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plus strand |
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Proteins
for BCRP3 gene
(According to
1UniProtKB,
HORDE,
2neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to PhosphoSitePlus,
Specific Peptides from DME,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Cloud-Clone Corp.,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Cloud-Clone Corp.,
Antibodies by
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
LSBio,
Abcam, and/or
Cloud-Clone Corp.)
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UniProtKB: --
|
Domains /
Families
for BCRP3 gene(According to HGNC, IUPHAR, InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
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Function
for BCRP3 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
genOway,
transcription factor targeting from QIAGEN
and/or HOMER,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
SwitchGear Genomics,
Gene Editing from DNA2.0,
Clones from OriGene,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
ESI BIO,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Apr 2014 via
Entrez Gene.)
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Animal Models:
Cell Line
Products: |  | GenScript Custom overexpressing Cell Line Services for BCRP3 | |  | Browse ESI BIO Cell Lines and PureStem Progenitors for BCRP3  | In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for BCRP3 |
Localization
for BCRP3 gene
(According to UniProtKB, COMPARTMENTS Subcellular localization database,
Ontologies according to Gene Ontology Consortium 01 Apr 2014 via
Entrez Gene.)
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Pathways & Interactions
for BCRP3 gene
(SuperPaths according to PathCards,
Pathways according to
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Sino Biological,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
QIAGEN,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Apr 2014 via
Entrez Gene).
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Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for BCRP3
Interactions:
Search GeneGlobe Interaction Network for BCRP3
|
Drugs & Compounds
for BCRP3 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience,
ApexBio,
HMDB,
BitterDB, and/or
Novoseek,
Ligands according to IUPHAR,
and Drugs according to DrugBank,
Enzo Life Sciences, and/or
PharmGKB)
About This Section
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 Browse compounds at ApexBio
 Browse Tocris compounds for BCRP3
|
Transcripts
for BCRP3 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
Conferences by KenesGroup,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
SwitchGear Genomics,
Tagged/untagged cDNA clones from
OriGene,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene, and/or
QIAGEN
)
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Unigene Cluster for BCRP3: Breakpoint cluster region pseudogene 3 Hs.655234 [show with all ESTs]Unigene Representative Sequence: AK2970382 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000382243 ENST00000447261(uc011ajv.2)
Additional mRNA sequence: AK297038.1 NR_024494.1 6 DOTS entries: DT.40272767 DT.99964341 DT.100826983 DT.100826988 DT.102841720 DT.120677784
GeneLoc Exon Structure
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Expression
for BCRP3 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
Protein expression images according to data from SPIRE 1MOPED,
2PaxDb, and 3MaxQB,
plus additional links to
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
QIAGEN,
Primers from
OriGene, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
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BCRP3 expression in normal human tissues
(normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: CCACTTGGTG
About this image BCRP3 Protein expression data from MOPED1, PaxDb2 and
MaxQB3:  --
SOURCE GeneReport for Unigene cluster: Hs.655234
Custom PCR Arrays for BCRP3
Primer
Products: |  | Browse OriGene qPCR
| | | Search Pre-validated RT2 qPCR
Primer Assays in human, mouse, rat BCRP3 | | | QuantiTect SYBR Green Assays in human, mouse, rat BCRP3 | | | QuantiFast Probe-based Assays in human, mouse, rat BCRP3 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for BCRP3 |
Orthologs
for BCRP3 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
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--
ENSEMBL Gene Tree for BCRP3 (if available)
TreeFam Gene Tree for BCRP3 (if available) |
Paralogs
for BCRP3 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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Genomic Variants
for BCRP3 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
4UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD), the Human Cytochrome P450 Allele
Nomenclature Database, and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 22 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for BCRP3 (25028882 - 25049327 bp)
Structural Variations
Database of Genomic Variants (DGV) 7 variations for BCRP3: About this table
| | Site Specific Mutation Identification with PCR Assays |
|
Disorders
/ Diseases
for BCRP3 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Conferences by KenesGroup,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
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OMIM gene information: 113640
OMIM disorders: --
BCRP3 for disorders About GeneDecksing
Export disorders for BCRP3 gene to outside databases
|
Publications
for BCRP3 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
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PubMed articles for BCRP3 gene integrated from 10 sources:
(articles sorted by number of sources associating them with BCRP3) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Linear order of the four BCR-related loci in 22q11. (PubMed id 3267213)1, 3 Budarf M....Emanuel B.S. (Genomics 1988)
- Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (Genome Res. 2006)
- The DNA sequence of human chromosome 22. (PubMed id 10591208)1 Dunham I.... Wright H. (Nature 1999)
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External Searches for BCRP3 gene (in PubMed,
OMIM, and NCBI Bookshelf)
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|
Genome Databases showing BCRP3 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
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|
Other Databases showing BCRP3 gene
(According to HUGE)
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Specialized Databases showing BCRP3 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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About This Section
TryGeneCards Plus | Patent Information for BCRP3 gene:
Search GeneIP for patents involving BCRP3
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for BCRP3 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or
ApexBio, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory,
genOway)
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 | |
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| | | | |
 |
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|  | Block miRNA regulation of human, mouse, rat BCRP3 using miScript Target Protectors | | SeqTarget long-range PCR primers for resequencing BCRP3 | | | DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat BCRP3 | | Predesigned siRNA for gene silencing in human, mouse, rat BCRP3 | | | QuantiFast Probe-based Assays in human, mouse, rat BCRP3 | | QuantiTect SYBR Green Assays in human, mouse, rat BCRP3 | | | Custom PCR Arrays for BCRP3 | | Search Chromatin IP Primers for BCRP3 | | | Search Pre-validated RT2 qPCR Primer Assays in human, mouse, rat BCRP3 | | Search GeneGlobe Interaction Network for BCRP3 | | | Search Regulatory tfbs for BCRP3 |
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 |  |  |  | |
| | | Search Tocris compounds for BCRP3 |
| | |  |  |  |
 | | | | |
 |
 |
 |  | | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for BCRP3 |
| |  |  |  |  | | | Search ThermoFisher Antibodies for BCRP3 |
| | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat BCRP3 |
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