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Aliases for BCRP1 Gene

Aliases for BCRP1 Gene

  • Breakpoint Cluster Region Pseudogene 1 2 3 5
  • BCR-1 3

External Ids for BCRP1 Gene

Previous GeneCards Identifiers for BCRP1 Gene

  • GC14U990074
  • GC22M024654
  • GC22M024657
  • GC22M024777
  • GC22M024953
  • GC22M025175
  • GC22M024540
  • GC22M024662
  • GC22M025050
  • GC22M025467

Summaries for BCRP1 Gene

GeneCards Summary for BCRP1 Gene

BCRP1 (Breakpoint Cluster Region Pseudogene 1) is a Pseudogene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for BCRP1 Gene

Genomics for BCRP1 Gene

Regulatory Elements for BCRP1 Gene

Enhancers for BCRP1 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH22F024284 0.9 Ensembl ENCODE 12.6 -25.0 -24973 8.8 PKNOX1 SIN3A FEZF1 YY1 FOS ZNF202 SP3 JUNB TSHZ1 TBX21 POM121L9P GGTLC4P ADORA2A BCRP1 ZNF70 MIF-AS1 UPB1 ENSG00000228923 ENSG00000232545 ENSG00000272578
GH22F024200 0.9 FANTOM5 Ensembl ENCODE 12.1 +58.4 58363 10.8 HDGF ZNF133 ARID4B SIN3A DMAP1 ZNF48 YY1 GTF3C2 ZNF121 FOS SUSD2 MIF-AS1 CABIN1 GGTLC4P POM121L9P BCRP1 RPS10P29 SPECC1L SNRPD3 ENSG00000232545
GH22F024265 0.2 Ensembl 0.8 -2.1 -2136 0.2 ZNF316 EMSY MAFK BCRP1 RPS10P29
GH22F024264 0.7 Ensembl 0.8 -1.0 -1036 1.6 RAD51 ZBTB33 POM121L9P BCRP1 RPS10P29
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around BCRP1 on UCSC Golden Path with GeneCards custom track

Genomic Location for BCRP1 Gene

Chromosome:
22
Start:
24,257,400 bp from pter
End:
24,263,765 bp from pter
Size:
6,366 bases
Orientation:
Minus strand

Genomic View for BCRP1 Gene

Genes around BCRP1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
BCRP1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for BCRP1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for BCRP1 Gene

Proteins for BCRP1 Gene

Post-translational modifications for BCRP1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for BCRP1 Gene

Domains & Families for BCRP1 Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for BCRP1 Gene

Function for BCRP1 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for BCRP1 Gene

Localization for BCRP1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for BCRP1 Gene

Pathways & Interactions for BCRP1 Gene

SuperPathways for BCRP1 Gene

No Data Available

Interacting Proteins for BCRP1 Gene

Gene Ontology (GO) - Biological Process for BCRP1 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for BCRP1 Gene

Transcripts for BCRP1 Gene

mRNA/cDNA for BCRP1 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for BCRP1 Gene

No ASD Table

Relevant External Links for BCRP1 Gene

GeneLoc Exon Structure for
BCRP1
ECgene alternative splicing isoforms for
BCRP1

Expression for BCRP1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for BCRP1 Gene

mRNA differential expression in normal tissues according to GTEx for BCRP1 Gene

This gene is overexpressed in Testis (x16.5).

NURSA nuclear receptor signaling pathways regulating expression of BCRP1 Gene:

BCRP1
genes like me logo Genes that share expression patterns with BCRP1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for BCRP1 Gene

Orthologs for BCRP1 Gene

This gene was present in the common ancestor of animals.

Orthologs for BCRP1 Gene

Organism Taxonomy Gene Similarity Type Details
fruit fly
(Drosophila melanogaster)
Insecta CG7380 36
  • 64 (a)
Species where no ortholog for BCRP1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for BCRP1 Gene

ENSEMBL:
Gene Tree for BCRP1 (if available)
TreeFam:
Gene Tree for BCRP1 (if available)

Paralogs for BCRP1 Gene

No data available for Paralogs for BCRP1 Gene

Variants for BCRP1 Gene

Relevant External Links for BCRP1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
BCRP1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for BCRP1 Gene

Disorders for BCRP1 Gene

Relevant External Links for BCRP1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
BCRP1

No disorders were found for BCRP1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for BCRP1 Gene

Publications for BCRP1 Gene

  1. Linear order of the four BCR-related loci in 22q11. (PMID: 3267213) Budarf M. … Emanuel B.S. (Genomics 1988) 2 3 64
  2. Curcumin Affects Phase II Disposition of Resveratrol Through Inhibiting Efflux Transporters MRP2 and BCRP. (PMID: 26502886) Ge S. … Hu M. (Pharm. Res. 2016) 3 64
  3. The cancer stem cell antigens CD133, BCRP1/ABCG2 and CD117/c-KIT are not associated with prognosis in resected early-stage non-small cell lung cancer. (PMID: 22199321) Herpel E. … Gottschling S. (Anticancer Res. 2011) 3 64

Products for BCRP1 Gene

Sources for BCRP1 Gene

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