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BCORL2 Gene

protein-coding   GIFtS: 31

GC0YM021617
BCL6 co-repressor-like 2
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc , and/or 7Ensembl, 8miRBase)
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Aliases & Descriptions
BCL6 co-repressor-like 21 2
FLJ398211 2
BCL-6 corepressor-like protein 22 3
BCoR-like protein 22
BCL6 co-repressor pseudogene2

External Ids:    HGNC: 239531   Entrez Gene: 2865542   Ensembl: ENSG000002155807   UniProtKB: Q8N8883   

Search outside databases for aliases for BCORL2 gene

Previous GC identifers: GC0YM020005 GC0YM020076

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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  --
(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC and Ensembl (release 56), Regulatory elements and Epigenetics data according to SABiosciences)
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Regulatory elements:
"" SABiosciences Regulatory transcription factor binding sites in the BCORL2 gene upstream (promoter) region "":
FOXF2   Oct-B1   oct-B3   oct-B2   POU2F1   POU2F2   POU2F2 (Oct-2.1)   POU2F2B   POU2F2C   FAC1   

Epigenetics:
"" SABiosciences Methyl-Profiler DNA Methylation qPCR Primer Assays for BCORL2:  ""
MePH28212-2A   

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: Yq11.222   Ensembl cytogenetic band:  Yq11.223   HGNC cytogenetic band: Yq11.222

BCORL2 Gene in genomic location: bands according to Ensembl, locations according to "" (and/or Entrez Gene and/or Ensembl if different)
""

GeneLoc gene densities for chromosome Y         GeneLoc Exon Structure

GeneLoc location for GC0YM021617:  view genomic region     (about GC identifiers)

Start:
21,617,317 bp from pter
End:
21,665,039 bp from pter
Size:
47,723 bases
Orientation:
minus strand
RefSeq DNA sequence:
NC_000024.9  NT_011875.12  
(According to 1UniProtKB, and/or Ensembl, Phosphorylation sites according to 2Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene, Novus Biologicals, and/or Sino Biological,
Biochemical Assays by Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 May 2010 and Entrez Gene, Antibodies by Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abnova, OriGene, Novus Biologicals, and/or Epitomics)
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UniProtKB/Swiss-Prot: BCOR2_HUMAN, Q8N888 (See protein sequence)
Recommended Name: BCoR-like protein 2  
Size: 145 amino acids; 16258 Da

REFSEQ proteins: NP_001166884.1  
Human Recombinant Proteins 
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""Novus Biologicals Protein for BCORL2  ""
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Antibodies for BCORL2: 
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Assays for BCORL2: 
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(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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ProtoNet protein and cluster: Q8N888

UniProtKB/Swiss-Prot: BCOR2_HUMAN, Q8N888
Similarity: Belongs to the BCOR family

(According to MGI May 08 2010, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Millipore, Abnova, siRNAs from Applied Biosystems, Sigma-Aldrich, Clones from Millipore, Sigma-Aldrich, OriGene, Sino Biological, Ontologies according to Gene Ontology Consortium 01 May 2010 via Entrez Gene.)
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Inhib.
RNA:
""Browse for Gene Knock-down Tools from Millipore
""Browse Abnova for Chimera RNAi Products
"" Origene 29mer shRNA kits in GFP-retroviral vector (see all 3): BCORL2
Origene shRNA RFP (see all 3): BCORL2
Origene basic RS shRNA (see all 3): BCORL2

""Applied Biosystems Silencer® siRNAs for BCORL2
""Sigma-Aldrich siRNA for BCORL2
Sigma-Aldrich shRNA for BCORL2
Explore Sigma-Aldrich super-pooled esiRNAs
Clones:""Browse Clones for the Expression of Recombinant Proteins Available from Millipore
""Browse iPSC Reprogramming Factors at Sigma-Aldrich
""Browse Origene untagged/tagged cDNA clones in CMV expression vector
""Browse Sino Biological Human cDNA Clones  ""
(Pathways according to Millipore, Cell Signaling Technology, Sigma-Aldrich, Applied Biosystems GeneAssist, KEGG and/or UniProtKB, (map by GeneGo),
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to 1UniProtKB, 2MINT, and/or 3STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 May 2010 via Entrez Gene).
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"" Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for BCORL2
(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
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"" Browse drugs & compounds from Enzo Life Sciences
""Browse Small Molecules at Sigma-Aldrich

"" Browse Tocris compounds for BCORL2

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 223 Homo sapiens; Apr 2 2010) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Millipore and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene, microRNA from SABiosciences,
Tagged/untagged cDNA clones from OriGene, Primers from OriGene and/or SABiosciences,
Expression Assays from Applied Biosystems)
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Inhib.
RNA:
""Browse for Gene Knock-down Tools from Millipore
""Browse Abnova for Chimera RNAi Products
"" Origene 29mer shRNA kits in GFP-retroviral vector (see all 3): BCORL2
Origene shRNA RFP (see all 3): BCORL2
Origene basic RS shRNA (see all 3): BCORL2

""Sigma-Aldrich siRNA for BCORL2
Sigma-Aldrich shRNA for BCORL2
Explore Sigma-Aldrich super-pooled esiRNAs

microRNA:""Search SABiosciences for microRNAs that regulate BCORL2: ""

Clones:"" clones: 
Primers:"" Origene genome-wide validated SYBR primer pairs: BCORL2
""SABiosciences RT2 qPCR Primer Assay for BCORL2: PPH14494A ""

REFSEQ mRNAs for BCORL2 gene: 

NM_001173413.1  

Additional cDNA sequence: 

AK303164.1 BC063452.1 BC110520.1 BC110521.1 BC122539.1 

3 DOTS entries:

DT.101978166  DT.95292065  DT.75128822 

6 AceView cDNA sequences:

BX103633 AK097140 NM_173700 BC063452 AI864885 BI827229 

"" highest scoring ESTs for BCORL2:

BC063452 BI827229 AK097140 AI864885 BC110520 BC110521 BC122539 BX103633 DA874086 DA938523 

Unigene Cluster for BCORL2:

BCL6 co-repressor-like 2
Hs.211713  [show with all ESTs]
Unigene Representative Sequence: BC063452


GeneLoc Exon Structure

2 Ensembl transcripts including schematic representations:
ENST00000441139  ENST00000400605  
(Experimental results according to 1GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to 2GeneAnnot , 3GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 223 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems, Primers from OriGene and/or SABiosciences )
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BCORL2 expression in normal and diseased human tissues

"" Applied Biosystems TaqMan ® Gene Expression Assays for BCORL2

1""  / 2""

1 probe-set matching BCORL2 gene

Affymetrix
probe-set
Array  GeneAnnot data GeneNote data GeneTide data
# genes Sensitivity Specificity Correlation Length Gb_Accession Consensus Uniqueness Score Rank
1562313_at2 U133Plus2 1 0.55 1.00 -- -- -- -- -- -- --
About this table
Data from Genenote  (Publications) and GNF BioGPS
    About these images
About these images

CGAP SAGE TAG: GTGCAGTTGA

SOURCE GeneReport for Unigene cluster: Hs.211713
Primers:"" Origene genome-wide validated SYBR primer pairs: BCORL2 ""
""SABiosciences RT2 qPCR Primer Assay for BCORL2: PPH14494A ""
(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD and/or 5MGI May 08 2010, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
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ENSEMBL Gene Tree for BCORL2
(Paralogs according to 1HomoloGene
and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
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(SNPs according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Genotyping Reagents from Applied Biosystems)
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Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)  ""
Database of Genomic Variants (DGV): 1 variation for BCORL2
     1 CNV: 31588
(in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, LSDB, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
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(Possibly Related Articles in Doctor's Guide)
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(in PubMed. Associations of this gene to articles via 1Novoseek, 2HGNC, 3Entrez Gene, 4UniProtKB/Swiss-Prot, 5UniProtKB/TrEMBL, 6GAD, and/or 7PharmGKB)
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4 PubMed articles for BCORL2 gene:
(in PubMed, OMIM, and NCBI Bookshelf)
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 ANDOR
Aliases
Free Text  

  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)
(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 286554 HGNC: 23953 AceView: BCORL2 Ensembl:ENSG00000215580 euGenes: HUgn286554
ECgene: BCORL2 H-InvDB: BCORL2
(According to HUGE)
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  --
(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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  --
(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from XenneX, Inc.)
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Patent Information for BCORL2 gene: ""
Search GeneIP for patents involving BCORL2

GeneCards and IP: ""
Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search


(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Novus Biologicals,
Epitomics, Sigma-Aldrich, R&D Systems, SABiosciences, Millipore, Abnova,
Clones available from OriGene, Sigma-Aldrich, Sino Biological, Drugs and/or compounds by Sigma-Aldrich, Enzo Life Sciences, and/or Tocris Bioscience)
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""
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Products for BCORL2:
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 ""  ""
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"" Recombinant & Natural Proteins  

"" Recombinant Proteins (BCORL2)
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""""""""
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"" Western blot validated antibodies
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"" Custom immunoassay development
"" Search Tocris compounds for BCORL2
"" Regulatory tfbs in BCORL2 upstream (promoter) region
"" Search Chromatin IP Primers for BCORL2
"" DNA Methylation qPCR Primer Assays for BCORL2
"" RT2 qPCR Primer Assay for BCORL2
"" Search GNC Networks for BCORL2
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