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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

BCL9L Gene

protein-coding   GIFtS: 49
GCID: GC11M118766

B-Cell CLL/Lymphoma 9-Like

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
B-Cell CLL/Lymphoma 9-Like1 2     BCL9-Like Protein2 3
Protein BCL9-22 3     BCL9-22
DLNB112 3     B-Cell CLL/Lymphoma 9-Like Protein2
B-Cell Lymphoma 9-Like Protein2 3     Nuclear Co-Factor Of Beta-Catenin Signalling2

External Ids:    HGNC: 236881   Entrez Gene: 2831492   Ensembl: ENSG000001861747   OMIM: 6090045   UniProtKB: Q86UU03   

Export aliases for BCL9L gene to outside databases

Previous GC identifers: GC11M118304 GC11M118272 GC11M114706


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for BCL9L Gene: 
BCL9L (B-cell CLL/lymphoma 9-like) is a protein-coding gene. Diseases associated with BCL9L include b-cell lymphomas, and adenoma, and among its related super-pathways are Wnt signaling pathway. GO annotations related to this gene include transcription coactivator activity and beta-catenin binding. An important paralog of this gene is BCL9.

UniProtKB/Swiss-Prot: BCL9L_HUMAN, Q86UU0
Function: Transcriptional regulator that acts as an activator. Promotes beta-catenin transcriptional activity.
Plays a role in tumorigenesis. Enhances the neoplastic transforming activity of CTNNB1 (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000011.9  NT_033899.8  NC_018922.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the BCL9L gene promoter:
         E2F-4   E2F-3a   E2F-5   E2F-2   E47   c-Ets-1   E2F   E2F-1   Hand1   AP-2alpha   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): BCL9L promoter sequence
   Search SABiosciences Chromatin IP Primers for BCL9L

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat BCL9L


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 11q23.3   Ensembl cytogenetic band:  11q23.3   HGNC cytogenetic band: 11q23.3

BCL9L Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
BCL9L gene location

GeneLoc information about chromosome 11         GeneLoc Exon Structure

GeneLoc location for GC11M118766:  view genomic region     (about GC identifiers)

Start:
118,764,584 bp from pter      End:
118,796,317 bp from pter
Size:
31,734 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: BCL9L_HUMAN, Q86UU0 (See protein sequence)
Recommended Name: B-cell CLL/lymphoma 9-like protein  
Size: 1499 amino acids; 157129 Da
Subunit: Found in a complex with CDC73; CTNNB1 and PYGO1. Interacts with CTNNB1
Subcellular location: Nucleus
Sequence caution: Sequence=AAH33257.1; Type=Erroneous initiation; Sequence=BAC85500.1; Type=Erroneous initiation;
Sequence=BAC85512.1; Type=Erroneous initiation;
1 PDB 3D structure from and Proteopedia for BCL9L:
2XB1 (3D)    
Secondary accessions: A1A4C1 Q67FY1 Q6ZWJ0 Q6ZWK2
Alternative splicing: 4 isoforms:  Q86UU0-1   Q86UU0-2   Q86UU0-3   Q86UU0-4   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for BCL9L: NX_Q86UU0

Explore proteomics data for BCL9L at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q86UU0

  • BCL9L Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    BCL9L Protein Expression
    REFSEQ proteins: NP_872363.1  
    ENSEMBL proteins: 
     ENSP00000335320   ENSP00000432804  

    Human Recombinant Protein Products for BCL9L: 
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    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Browse Proteins at Cloud-Clone Corp. 

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA--
    GO:0005730NOT nucleolus IDA--

    BCL9L for ontologies           About GeneDecksing



    BCL9L Antibody Products: 
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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    2 InterPro protein domains:
     IPR024670 BCL9_beta-catenin-bd_dom
     IPR015668 Bcl-9

    Graphical View of Domain Structure for InterPro Entry Q86UU0

    ProtoNet protein and cluster: Q86UU0

    UniProtKB/Swiss-Prot: BCL9L_HUMAN, Q86UU0
    Domain: Tne C-terminal domain is important for its transactivation activity (By similarity)
    Similarity: Belongs to the BCL9 family


    BCL9L for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: BCL9L_HUMAN, Q86UU0
    Function: Transcriptional regulator that acts as an activator. Promotes beta-catenin transcriptional activity.
    Plays a role in tumorigenesis. Enhances the neoplastic transforming activity of CTNNB1 (By similarity)

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003713transcription coactivator activity NAS19328798
    GO:0008013beta-catenin binding IDA15574752
         
    BCL9L for ontologies           About GeneDecksing


    Phenotypes:
         2 GenomeRNAi human phenotypes for BCL9L:
     Decreased Wnt reporter activit  Wnt reporter downregulated 

         1 MGI mutant phenotype (inferred from 1 allele(MGI details for Bcl9l):
     muscle 

    BCL9L for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for BCL9L 
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for BCL9L 
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    miRNA
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    SwitchGear 3'UTR luciferase reporter plasmidBCL9L 3' UTR sequence
    Inhib. RNA
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for BCL9L


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for BCL9L About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Wnt signaling pathway
    Wnt Signaling Pathway0.40

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways

    1 R&D Systems Pathway for BCL9L
        Wnt Signaling Pathway



    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for BCL9L

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    2 Interacting proteins for BCL9L (Q86UU02, 3 ENSP000003353204) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CTNNB1P352223, ENSP000003444564I2D: score=1 STRING: ENSP00000344456
    --P310162MINT-8105937 MINT-8106343
    About this table

    Gene Ontology (GO): 5/8 biological process terms (GO ID links to tree view) (see all 8):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006351transcription, DNA-dependent IEA--
    GO:0010718positive regulation of epithelial to mesenchymal transition IMP19328798
    GO:0022604regulation of cell morphogenesis IMP19328798
    GO:0030512negative regulation of transforming growth factor beta receptor signaling pathway IMP19328798
    GO:0035019somatic stem cell maintenance IEA--

    BCL9L for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for BCL9L

    Search CenterWatch for drugs/clinical trials and news about BCL9L

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for BCL9L gene: 
    NM_182557.2  

    Unigene Cluster for BCL9L:

    B-cell CLL/lymphoma 9-like
    Hs.414740  [show with all ESTs]
    Unigene Representative Sequence: NM_182557
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000334801(uc001pug.3 uc009zal.3) ENST00000526143 ENST00000526514
    ENST00000530293 ENST00000527266 ENST00000532899
    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat BCL9L
    8/74 QIAGEN miScript miRNA Assays for microRNAs that regulate BCL9L (see all 74):
    hsa-miR-607 hsa-miR-15a hsa-miR-1224-3p hsa-miR-138-2* hsa-miR-637 hsa-miR-761 hsa-miR-34c-5p hsa-miR-130a*
    SwitchGear 3'UTR luciferase reporter plasmidBCL9L 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for BCL9L
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat BCL9L
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    Primer
    Products:
        
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat BCL9L
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat BCL9L

    Additional mRNA sequence: 

    AB094091.1 AK122650.1 AK122882.1 AY296059.1 BC033257.1 

    7 DOTS entries:

    DT.40250888  DT.100671753  DT.40109977  DT.95335895  DT.120727423  DT.212254  DT.40250893 

    24/135 AceView cDNA sequences (see all 135):

    BF476567 AB094091 BQ937674 BF438189 BQ931752 AW024061 BU624696 AY296059 
    BU624631 AI348687 BC033257 BQ226630 BQ879029 BU838512 AK122650 BM466326 
    BU729067 BU170053 AI298130 AL534956 AW295172 AA470525 CR606474 BU159314 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    BCL9L expression in normal human tissues (normalized intensities)      BCL9L embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    BCL9L Expression
    About this image


    BCL9L expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/32 selected tissues (see all 32) fully expand
     
     Bone (Muscoskeletal System)    fully expand to see all 12 entries
             Zeugopod Long Bone
             skeleton/pectoral girdle and thoracic body wall/sternum   
     
     Cartilage (Muscoskeletal System)    fully expand to see all 5 entries
             Meckel's Cartilage
             sensory organ/ear/inner ear   
     
     Epithelium (Reproductive System)    fully expand to see all 5 entries
             vagina ; squamous epithelial cells   
     
     Neural Crest (Gastrulation Derivatives)    fully expand to see all 3 entries
             skeleton/cranium/chondrocranium   
     
     Testis (Reproductive System)    fully expand to see all 2 entries
             Leydig Cells Testis Interstitium
             seminal vesicle ; glandular cells   

    See BCL9L Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for BCL9L

    SOURCE GeneReport for Unigene cluster: Hs.414740

    UniProtKB/Swiss-Prot: BCL9L_HUMAN, Q86UU0
    Tissue specificity: Expressed in breast, ductal and invasive ductal carcinomas of the breast, sporadic colorectal
    adenomas and carcinomas (at protein level). Expressed in fetal brain. Expressed in lung, amygdala, eye, prostate,
    pancreatic and prostate cancers, head and neck tumors and embryonal tumor

        SABiosciences Expression via Pathway-Focused PCR Array including BCL9L: 
              Stem Cell Signaling in human mouse rat

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for BCL9L

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals and fungi.

    Orthologs for BCL9L gene from 7/13 species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Bcl9l1 , 5 B cell CLL/lymphoma 9-like1, 5 90.05(n)1
    94.24(a)1
      9 (24.84 cM)5
    802881  NM_030256.21  NP_084532.21 
     444991365 
    chicken
    (Gallus gallus)
    Aves BCL9L1 B-cell CLL/lymphoma 9-like 74.03(n)
    75.76(a)
      419785  XM_417923.3  XP_417923.3 
    lizard
    (Anolis carolinensis)
    Reptilia BCL9L6
    Uncharacterized protein
    65(a)
    1 ↔ 1
    GL344088.1(4915-15100)
    zebrafish
    (Danio rerio)
    Actinopterygii bcl9l1 B-cell CLL/lymphoma 9-like 57.34(n)
    54.06(a)
      449532  NM_001005575.1  NP_001005575.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta DLP6
    ph-d6
    (see all 8)
    polyhomeotic distal
    (see all 8)
    5(a)
    5(a)
    (see all 8)
    possible ortholog
    possible ortholog
    (see all 8)
    2L(6480956-6487585)
    X(2010899-2017164)
    worm
    (Caenorhabditis elegans)
    Secernentea nra-36
    pqn-206
    (see all 9)
    Protein PQN-20
    (see all 9)
    9(a)
    5(a)
    (see all 9)
    possible ortholog
    possible ortholog
    (see all 9)
    X(9925923-9931460)
    I(6791025-6797470)
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes GAL116
    Subunit of the RNA polymerase II mediator complex;...
    1(a)
    1 → many
    XV(234940-238185)


    ENSEMBL Gene Tree for BCL9L (if available)
    TreeFam Gene Tree for BCL9L (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for BCL9L gene
    BCL92  

    BCL9L for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/404 SNPs in BCL9L are shown (see all 404)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 11 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs754380461,2
    C,F--118767564(+) CTCCCG/AAGGCA 1 -- ut311Minor allele frequency- A:0.01EA 120
    rs1810365451,2
    --118767605(+) TTACTC/TCTGGG 1 -- ut310--------
    rs1164546801,2
    C,F--118767666(+) AAAGGC/TGGATA 1 -- ut311Minor allele frequency- T:0.02WA 118
    rs5199251,2
    H--118767769(-) CCTCTG/TCCCAG 1 -- ut31 ese35Minor allele frequency- T:0.00MN NS EA 598
    rs1159266451,2
    C,F--118767811(+) AGGAGG/ACGGCA 1 -- ut311Minor allele frequency- A:0.04WA 118
    rs735754111,2
    C,F--118767832(+) TCCCCG/AATTCC 1 -- ut312Minor allele frequency- A:0.50WA 4
    rs783483291,2
    C,F--118767925(+) CAGCAG/ACCTCT 1 -- ut312Minor allele frequency- A:0.05WA 120
    rs1472833861,2
    --118768029(+) GGGGG-/CCCACA 1 -- ut310--------
    rs1855007741,2
    --118768100(+) GGCTAA/TGATGT 1 -- ut310--------
    rs1898454131,2
    --118768182(+) ATGCAA/CGTGCA 1 -- ut310--------

    HapMap Linkage Disequilibrium report for BCL9L (118764584 - 118796317 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for BCL9L: --

    Human Gene Mutation Database (HGMD): BCL9L
    SABiosciences Cancer Mutation PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 609004    OMIM disorders: --

    7 diseases for BCL9L:    About MalaCards
    b-cell lymphomas    adenoma    colorectal cancer    prostate cancer
    prostatitis    pancreatitis    breast cancer


    BCL9L for disorders           About GeneDecksing

    Genetic Association Database (GAD): BCL9L

    Export disorders for BCL9L gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for BCL9L gene, integrated from 9 sources (see all 25):
    (articles sorted by number of sources associating them with BCL9L)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Identification and characterization of human BCL9L gene and mouse Bcl9l gene in silico. (PubMed id 12964048)1, 2, 3, 9 Katoh M. and Katoh M. (2003)
    2. BCL9-2 binds Arm/beta-catenin in a Tyr142-independent manner and requires Pygopus for its function in Wg/Wnt signaling. (PubMed id 17113272)1, 2, 9 Hoffmans R. and Basler K. (2007)
    3. Crystal structure of a beta-catenin/BCL9/Tcf4 complex. (PubMed id 17052462)1, 2 Sampietro J.... Xu W. (2006)
    4. Essential role of BCL9-2 in the switch between beta-catenin's adhesive and transcriptional functions. (PubMed id 15371335)1, 2 Brembeck F.H.... Birchmeier W. (2004)
    5. Identification of a link between Wnt/b-catenin signall ing and the cell fusion pathway. (PubMed id 22109522)1 Matsuura K....Akiyama T. (2011)
    6. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
    7. BCL9-2 promotes early stages of intestinal tumor prog ression. (PubMed id 21703997)1 Brembeck F.H....Birchmeier W. (2011)
    8. System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PubMed id 21406692)2 Rigbolt K.T....Blagoev B. (2011)
    9. Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. (PubMed id 20068231)2 Olsen J.V....Mann M. (2010)
    10. The SH3 domain of postsynaptic density 95 mediates inf lammatory pain through phosphatidylinositol-3-kinase recruitment. (PubMed id 20467438)1 Arbuckle M.I....Grant S.G. (2010)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
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      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 283149 HGNC: 23688 AceView: BCL9L Ensembl:ENSG00000186174 euGenes: HUgn283149
    ECgene: BCL9L H-InvDB: BCL9L

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for BCL9L Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for BCL9L Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for BCL9L gene:
    Search GeneIP for patents involving BCL9L

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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