Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



BCL7C Gene

protein-coding   GIFtS: 53
GCID: GC16M030849

B-Cell CLL/Lymphoma 7C

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

Aliases
B-Cell CLL/Lymphoma 7C1 2
B-Cell CLL/Lymphoma 7 Protein Family Member C2

External Ids:    HGNC: 10061   Entrez Gene: 92742   Ensembl: ENSG000000993857   OMIM: 6058475   UniProtKB: Q8WUZ03   

Export aliases for BCL7C gene to outside databases

Previous GC identifers: GC16P9B0085 GC16M031396 GC16M030896 GC16M030935 GC16M030806 GC16M030847


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

Entrez Gene summary for BCL7C Gene:
This gene is identified by the similarity of its product to the N-terminal region of BCL7A protein. The BCL7A
protein is encoded by the gene known to be directly involved in a three-way gene translocation in a Burkitt
lymphoma cell line. The function of this gene has not yet been determined. Two transcript variants encoding
different isoforms have been found for this gene. (provided by RefSeq, Nov 2013)

GeneCards Summary for BCL7C Gene:
BCL7C (B-cell CLL/lymphoma 7C) is a protein-coding gene. Diseases associated with BCL7C include burkitt's lymphoma, and hodgkin's lymphoma. An important paralog of this gene is BCL7B.

UniProtKB/Swiss-Prot: BCL7C_HUMAN, Q8WUZ0
Function: May play an anti-apoptotic role (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
RefSeq DNA sequence:
NC_000016.10  NC_018927.2  NT_187260.1  
Regulatory elements:
   Regulatory transcription factor binding sites in the BCL7C gene promoter:
         STAT1   p53   STAT1beta   CUTL1   NF-kappaB   STAT1alpha   STAT3   ARP-1   NF-kappaB1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidBCL7C promoter sequence
   Search Chromatin IP Primers for BCL7C

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat BCL7C


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 16p11   Ensembl cytogenetic band:  16p11.2   HGNC cytogenetic band: 16p11

BCL7C Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
BCL7C gene location

GeneLoc information about chromosome 16         GeneLoc Exon Structure

GeneLoc location for GC16M030849:  view genomic region     (about GC identifiers)

Start:
30,844,947 bp from pter      End:
30,906,281 bp from pter
Size:
61,335 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: BCL7C_HUMAN, Q8WUZ0 (See protein sequence)
Recommended Name: B-cell CLL/lymphoma 7 protein family member C  
Size: 217 amino acids; 23468 Da
Secondary accessions: O43770 Q6PD89
Alternative splicing: 2 isoforms:  Q8WUZ0-1   Q8WUZ0-2   

Explore the universe of human proteins at neXtProt for BCL7C: NX_Q8WUZ0

Explore proteomics data for BCL7C at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See BCL7C Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_001273455.1  NP_004756.2  

    ENSEMBL proteins: 
     ENSP00000369674   ENSP00000461177   ENSP00000459007   ENSP00000215115  

    BCL7C Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    OriGene Protein Over-expression Lysate for BCL7C
    OriGene Custom MassSpec
    OriGene Custom Protein Services for BCL7C
    GenScript Custom Purified and Recombinant Proteins Services for BCL7C
    Novus Biologicals BCL7C Proteins
    Novus Biologicals BCL7C Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Browse Proteins at Cloud-Clone Corp.

    BCL7C Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for BCL7C
    Novus Biologicals BCL7C Antibodies
    Abcam antibodies for BCL7C
    Browse Antibodies at Cloud-Clone Corp.
    ThermoFisher Antibodies for BCL7C
    LSBio Antibodies in human, mouse, rat for BCL7C

    BCL7C Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for BCL7C
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for BCL7C
    Browse Enzo Life Sciences for kits & assays
    Browse ELISAs at Cloud-Clone Corp.
    Browse CLIAs at Cloud-Clone Corp.


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TryGeneCards Plus
    1 InterPro protein domain:
     IPR006804 BCL7

    Graphical View of Domain Structure for InterPro Entry Q8WUZ0

    ProtoNet protein and cluster: Q8WUZ0

    UniProtKB/Swiss-Prot: BCL7C_HUMAN, Q8WUZ0
    Similarity: Belongs to the BCL7 family


    BCL7C for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: BCL7C_HUMAN, Q8WUZ0
    Function: May play an anti-apoptotic role (By similarity)

         Genatlas biochemistry entry for BCL7C:
    putative F-actin cross-linking protein 12,homolog,BCL7A family

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for BCL7C
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for BCL7C

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for BCL7C
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for BCL7C

    miRNA
    Products:
        
    miRTarBase miRNAs that target BCL7C:
    hsa-mir-155-5p (MIRT020663)

    Block miRNA regulation of human, mouse, rat BCL7C using miScript Target Protectors
    Search for qRT-PCR Assays for microRNAs that regulate BCL7C
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for BCL7C
    Predesigned siRNA for gene silencing in human, mouse, rat BCL7C

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for BCL7C

    Clone
    Products:
         
    OriGene clones in human, mouse for BCL7C (see all 6)
    OriGene ORF clones in mouse, rat for BCL7C
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: BCL7C (NM_004765)
    Sino Biological Human cDNA Clone for BCL7C
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for BCL7C
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat BCL7C

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for BCL7C
    Browse ESI BIO Cell Lines and PureStem Progenitors for BCL7C 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for BCL7C


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus3
    mitochondrion2

    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
    About This Section

    TryGeneCards Plus




        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for BCL7C
    Interactions:

        Search GeneGlobe Interaction Network for BCL7C

    STRING Interaction Network Preview (showing 5 interactants - click image to see 15)

    Selected Interacting proteins for BCL7C (Q8WUZ02, 3 ENSP000002151154) via UniProtKB, MINT, STRING, and/or I2D (see all 591)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ACTBP607092, 3, ENSP000003499604MINT-7945693 I2D: score=1 STRING: ENSP00000349960
    ARID1AO144972, 3, ENSP000003204854MINT-7945693 I2D: score=1 STRING: ENSP00000320485
    SMARCB1Q128242, 3, ENSP000002631214MINT-7945693 I2D: score=1 STRING: ENSP00000263121
    SMARCD1Q96GM52, 3, ENSP000003784144MINT-7945693 I2D: score=1 STRING: ENSP00000378414
    SMARCE1Q969G32, 3, ENSP000003239674MINT-7945693 I2D: score=1 STRING: ENSP00000323967
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006915apoptotic process IEA--

    BCL7C for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
    About This Section

    TryGeneCards Plus
    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for BCL7C



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
    About This Section

    TryGeneCards Plus

    REFSEQ mRNAs for BCL7C gene (2 alternative transcripts): 
    NM_001286526.1  NM_004765.3  

    Unigene Cluster for BCL7C:

    B-cell CLL/lymphoma 7C
    Hs.658547  [show with all ESTs]
    Unigene Representative Sequence: BC058863
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000380317(uc021tgq.1) ENST00000574418 ENST00000576194 ENST00000572628
    ENST00000215115(uc002dzv.3)
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat BCL7C using miScript Target Protectors
    Search for qRT-PCR Assays for microRNAs that regulate BCL7C
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for BCL7C
    Predesigned siRNA for gene silencing in human, mouse, rat BCL7C
    Clone
    Products:
         
    OriGene clones in human, mouse for BCL7C (see all 6)
    OriGene ORF clones in mouse, rat for BCL7C
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: BCL7C (NM_004765)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for BCL7C
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat BCL7C
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for BCL7C
    OriGene qSTAR qPCR primer pairs in human, mouse for BCL7C
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat BCL7C
      QuantiTect SYBR Green Assays in human, mouse, rat BCL7C
      QuantiFast Probe-based Assays in human, mouse, rat BCL7C

    Additional mRNA sequence: 

    AJ223980.1 BC019071.1 BC058863.1 

    6 DOTS entries:

    DT.102621  DT.86850688  DT.446279  DT.91758025  DT.97814657  DT.91758026 

    Selected AceView cDNA sequences (see all 88):

    CK825699 BQ420735 BQ186087 AW249720 NM_004765 BC010017 BQ181046 CD518801 
    BU902606 BM682538 BU507579 BQ189495 BM790826 AJ223980 BC058863 BG760881 
    BM806243 CB243151 BU740339 BI668566 AI377560 BQ212740 BU160225 BU850184 

    GeneLoc Exon Structure

    2 Alternative Splicing Database (ASD) splice patterns (SP) for BCL7C    About this scheme

    ExUns: 1 ^ 2a · 2b ^ 3 ^ 4a · 4b ^ 5 ^ 6
    SP1:                                -               
    SP2:                                                


    ECgene alternative splicing isoforms for BCL7C

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TryGeneCards Plus

    BCL7C expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GCCGGCCGGA
    BCL7C Expression
    About this image

    BCL7C Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    BCL7C Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.658547

    UniProtKB/Swiss-Prot: BCL7C_HUMAN, Q8WUZ0
    Tissue specificity: Ubiquitous

        Custom PCR Arrays for BCL7C
    Primer
    Products:
    OriGene qPCR primer pairs and template standards for BCL7C
    OriGene qSTAR qPCR primer pairs in human, mouse for BCL7C
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat BCL7C
    QuantiTect SYBR Green Assays in human, mouse, rat BCL7C
    QuantiFast Probe-based Assays in human, mouse, rat BCL7C
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for BCL7C

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    TryGeneCards Plus

    This gene was present in the common ancestor of animals.

    Orthologs for BCL7C gene from Selected species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Bcl7c1 , 5 B cell CLL/lymphoma 7C1, 5 90.32(n)1
    93.09(a)1
      7 (69.65 cM)5
    120551  NM_009746.21  NP_033876.11 
     1276633535 
    lizard
    (Anolis carolinensis)
    Reptilia BCL7C6
    B-cell CLL/lymphoma 7C
    53(a)
    1 ↔ 1
    GL343220.1(1716531-1729286)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia LOC1001586181 uncharacterized LOC100158618 58.59(n)
    52.02(a)
      100158618  NM_001128034.1  NP_001121506.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta BCL7-like6
    BCL7-like
    32(a)
    1 → many
    X(9250667-9252627)
    worm
    (Caenorhabditis elegans)
    Secernentea C28H8.16
    Protein C28H8.1 (C28H8.1) mRNA, complete cds
    33(a)
    1 → many
    III(5926060-5927166) WBGene00016192


    ENSEMBL Gene Tree for BCL7C (if available)
    TreeFam Gene Tree for BCL7C (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section

    TryGeneCards Plus
    Paralogs for BCL7C gene
    BCL7B2  BCL7A2  
    3 SIMAP similar genes for BCL7C using alignment to 3 protein entries:     BCL7C_HUMAN (see all proteins):
    BCL7B    SETMAR    BCL7A

    BCL7C for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
    About This Section

    TryGeneCards Plus

    Selected SNPs for BCL7C (see all 68)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 16 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1918006121,2
    --30899017(+) GTCCTC/GTCAGA 1 -- ds50010--------
    rs1843260781,2
    --30899020(+) CTCTCA/GGAGCC 1 -- ds50010--------
    rs2004634871,2
    --30899153(+) AGGGGC/TCCCTG 1 -- ut310--------
    rs1125181981,2
    C,F--30899393(+) GCCTCC/TACTCC 1 -- int11Minor allele frequency- T:0.50CSA 2
    rs752839781,2
    C--30899465(+) GGCACA/CAAAAA 1 -- int10--------
    rs1392943301,2
    C--30899473(+) AAACAA/GCAACG 1 -- int10--------
    rs787087521,2
    C,F--30899502(+) GGAACG/AAACCT 1 -- int11Minor allele frequency- A:0.02WA 118
    rs1901564261,2
    --30899546(+) GCCTCA/GTGAGA 1 -- int10--------
    rs1819295201,2
    --30899848(+) AGACGC/GGGTTT 1 -- int10--------
    rs1134289071,2
    C,F--30899946(+) CCACCG/ACGCCC 1 -- int11Minor allele frequency- A:0.50CSA 2

    HapMap Linkage Disequilibrium report for BCL7C (30844947 - 30906281 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 8 variations for BCL7C:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv905733CNV Loss21882294
    nsv905729CNV Loss21882294
    dgv35n68CNV Loss17160897
    dgv2670n71CNV Loss21882294
    nsv833189CNV Loss17160897
    nsv905728CNV Loss21882294
    nsv457483CNV Loss19166990
    dgv2671n71CNV Loss21882294

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing BCL7C
    DNA2.0 Custom Variant and Variant Library Synthesis for BCL7C

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TryGeneCards Plus
    OMIM gene information: 605847    OMIM disorders: --

    5 diseases for BCL7C:    About MalaCards
    burkitt's lymphoma    hodgkin's lymphoma    non-hodgkin lymphoma    hypoxia
    melanoma


    BCL7C for disorders           About GeneDecksing

    Genetic Association Database (GAD): BCL7C
    Human Genome Epidemiology (HuGE) Navigator: BCL7C (3 documents)

    Export disorders for BCL7C gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    TryGeneCards Plus

    PubMed articles for BCL7C gene, integrated from 10 sources (see all 23):
    (articles sorted by number of sources associating them with BCL7C)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The BCL7 gene family: deletion of BCL7B in Williams syndrome. (PubMed id 9931421)1, 2, 3, 9 Jadayel D.M.... Dyer M.J.S. (Gene 1998)
    2. Association between genetic variants in VEGF, ERCC3 and occupational benzene haematotoxicity. (PubMed id 19773279)1, 4 Hosgood H.D....Lan Q. (Occup Environ Med 2009)
    3. Common genetic variants in candidate genes and risk of familial lymphoid malignancies. (PubMed id 19573080)1, 4 Liang X.S....Goldin L.R. (Br. J. Haematol. 2009)
    4. Risk of non-Hodgkin lymphoma associated with germline variation in genes that regulate the cell cycle, apoptosis, and lymphocyte development. (PubMed id 19336552)1, 4 Morton L.M....Hartge P. (amp 2009)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    6. Identification of the hypoxia-inducible factor 2I+ nuclear interactome in melanoma cells reveals master proteins involved in melanoma development. (PubMed id 23275444)1 Steunou A.L....Nieto L. (amp 2013)
    7. System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PubMed id 21406692)2 Rigbolt K.T....Blagoev B. (Sci. Signal. 2011)
    8. Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PubMed id 21832049)1 OlA!h J....OvA!di J. (J. Biol. Chem. 2011)
    9. Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. (PubMed id 20068231)2 Olsen J.V....Mann M. (Sci. Signal. 2010)
    10. Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach. (PubMed id 19413330)2 Gauci S....Mohammed S. (Anal. Chem. 2009)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

    TryGeneCards Plus
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

    TryGeneCards Plus
    Entrez Gene: 9274 HGNC: 1006 AceView: BCL7C Ensembl:ENSG00000099385 euGenes: HUgn9274
    ECgene: BCL7C H-InvDB: BCL7C

    (According to HUGE)
    About This Section

    TryGeneCards Plus
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

    TryGeneCards Plus
    NameDescription
    PharmGKB entry for BCL7C Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for BCL7C Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for BCL7C gene:
    Search GeneIP for patents involving BCL7C

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

    TryGeneCards Plus

     
     EMD Millipore genomic analysis products

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
     Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for BCL7C  
     OriGene qPCR primer pairs and template standards for BCL7C   OriGene Protein Over-expression Lysate for BCL7C  
     OriGene Custom Mass Spec   OriGene clones in human, mouse for BCL7C  
     OriGene qSTAR qPCR primer pairs in human, mouse for BCL7C   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
     OriGene ORF clones in mouse, rat for BCL7C   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for BCL7C   OriGene Custom Protein Services for BCL7C  

     
     
     Block miRNA regulation of human, mouse, rat BCL7C using miScript Target Protectors SeqTarget long-range PCR primers for resequencing BCL7C
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat BCL7C Predesigned siRNA for gene silencing in human, mouse, rat BCL7C
     QuantiFast Probe-based Assays in human, mouse, rat BCL7C QuantiTect SYBR Green Assays in human, mouse, rat BCL7C
     Custom PCR Arrays for BCL7C Search Chromatin IP Primers for BCL7C
     Pre-validated RT2 qPCR Primer Assay in human, mouse, rat BCL7C  Search GeneGlobe Interaction Network for BCL7C
     Regulatory tfbs in BCL7C promoter
     GenScript Custom Purified and Recombinant Proteins Services for BCL7C GenScript cDNA clones with any tag delivered in your preferred vector for BCL7C
     GenScript Custom Assay Services for BCL7C GenScript Custom overexpressing Cell Line Services for BCL7C
     CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
     Plasmid Preparation Custom Peptide Services
     Search for Antibodies & Assays

     Search Tocris compounds for BCL7C
     Browse Sino Biological Proteins
     Browse Sino Biological Cell Lysates
     cDNA Clones for BCL7C
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Tissue Slides
     BCL7C antibodies
     BCL7C proteins
     BCL7C lysates
     Antibodies for BCL7C
     See all of Abcam's Antibodies, Kits and Proteins for BCL7C
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins
     Browse Proteins at Cloud-Clone Corp.
     Browse Antibodies at Cloud-Clone Corp.
     Browse ELISAs at Cloud-Clone Corp.
     Browse CLIAs at Cloud-Clone Corp.



     Browse ESI BIO Cell Lines and PureStem Progenitors for BCL7C
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for BCL7C
     Browse SwitchGear 3'UTR luciferase reporter plasmids for BCL7C
     SwitchGear Promoter luciferase reporter plasmids for BCL7C
     ThermoFisher Antibodies for BCL7C
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat BCL7C
     inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for BCL7C
     inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for BCL7C
     LSBio Antibodies in human, mouse, rat for BCL7C
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
     Browse compounds at ApexBio
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014

    View Random Gene

    Category
    (GIFtS: )
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      BCL7C gene at Home site.
    Version: 3.12.136 22 July 2014
    hostname: 356977-web1.xennexinc.com index build: 126 solr: 1.4