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BCL7B Gene

protein-coding   GIFtS: 54
GCID: GC07M072950

B-Cell CLL/Lymphoma 7B

  See BCL7B-related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA

Quality score for the ORGUL clustered with this gene is 3

Aliases
B-Cell CLL/Lymphoma 7B1 2
B-Cell CLL/Lymphoma 7 Protein Family Member B2
Allergen Hom S 33

External Ids:    HGNC: 10051   Entrez Gene: 92752   Ensembl: ENSG000001066357   OMIM: 6058465   UniProtKB: Q9BQE93   
ORGUL members:         

Export aliases for BCL7B gene to outside databases

Previous GC identifers: GC07M071591 GC07M072348 GC07M072362 GC07M072395 GC07M072588 GC07M068832


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for BCL7B Gene:
This gene encodes a member of the BCL7 family including BCL7A, BCL7B and BCL7C proteins. This member is BCL7B,
which contains a region that is highly similar to the N-terminal segment of BCL7A or BCL7C proteins. The BCL7A
protein is encoded by the gene known to be directly involved in a three-way gene translocation in a Burkitt
lymphoma cell line. This gene is located at a chromosomal region commonly deleted in Williams syndrome. This gene
is highly conserved from C. elegans to human. Multiple alternatively spliced transcript variants have been found
for this gene. (provided by RefSeq, Oct 2010)

GeneCards Summary for BCL7B Gene:
BCL7B (B-cell CLL/lymphoma 7B) is a protein-coding gene. Diseases associated with BCL7B include small intestine adenocarcinoma, and supravalvular aortic stenosis. GO annotations related to this gene include actin binding. An important paralog of this gene is BCL7C.

UniProtKB/Swiss-Prot: BCL7B_HUMAN, Q9BQE9
Function: May play a role in lung tumor development or progression




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000007.13  NT_007933.16  NC_018918.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the BCL7B gene promoter:
         E2F-1   E2F   HSF1short   HSF1 (long)   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): BCL7B promoter sequence
   Search Chromatin IP Primers for BCL7B

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat BCL7B


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 7q11.23   Ensembl cytogenetic band:  7q11.23   HGNC cytogenetic band: 7q11.23

BCL7B Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
BCL7B gene location

GeneLoc information about chromosome 7         GeneLoc Exon Structure

GeneLoc location for GC07M072950:  view genomic region     (about GC identifiers)

Start:
72,950,683 bp from pter      End:
72,972,332 bp from pter
Size:
21,650 bases      Orientation:
minus strand

1 alternative location:
Chr7-,CRA_TCAG 72,283,755-72,305,137     

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: BCL7B_HUMAN, Q9BQE9 (See protein sequence)
Recommended Name: B-cell CLL/lymphoma 7 protein family member B  
Size: 202 amino acids; 22195 Da
Allergen: Causes an allergic reaction in human. Binds to IgE from atopic dermatitis (AD) patients. Identified as
an IgE autoantigen in atopic dermatitis (AD) patients with severe skin manifestations
Secondary accessions: A8K226 C9JWD3 D3DXF0 O43769 Q13845 Q6ZW75
Alternative splicing: 4 isoforms:  Q9BQE9-1   Q9BQE9-2   Q9BQE9-3   Q9BQE9-4   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for BCL7B: NX_Q9BQE9

Explore proteomics data for BCL7B at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys27
  • Modification sites at PhosphoSitePlus

  • See BCL7B Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_001184173.1  NP_001698.2  

    ENSEMBL proteins: 
     ENSP00000223368   ENSP00000393230   ENSP00000414473   ENSP00000414231   ENSP00000411073  
     ENSP00000406069  

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR006804 BCL7

    Graphical View of Domain Structure for InterPro Entry Q9BQE9

    ProtoNet protein and cluster: Q9BQE9

    UniProtKB/Swiss-Prot: BCL7B_HUMAN, Q9BQE9
    Similarity: Belongs to the BCL7 family


    Find genes that share domains with BCL7B           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: BCL7B_HUMAN, Q9BQE9
    Function: May play a role in lung tumor development or progression

         Genatlas biochemistry entry for BCL7B:
    putative F-actin cross linking protein 12 homolog,BCL7A family,involved in cellular and developmental
    functions,highly expressed in heart,skeletal muscle and fetal liver,located in the commonly Williams
    region,atopy-related IgE autoantigen,detected in the serum of patients with severe atopic dermatitis,not
    rearranged in lymphoid malignancies

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003779actin binding NAS8605326
         
    Find genes that share ontologies with BCL7B           About GenesLikeMe


    Phenotypes:
         4 GenomeRNAi human phenotypes for BCL7B:
     Cell division defect  Increased G2M DNA content  Increased gamma-H2AX phosphory  Increased number of mitotic ce 

    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for BCL7B

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    hsa-mir-23b-3p (MIRT046246), hsa-mir-106b-3p (MIRT038593)

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    Selected qRT-PCR Assays for microRNAs that regulate BCL7B (see all 30):
    hsa-miR-26a-2* hsa-miR-607 hsa-miR-148b hsa-miR-4318 hsa-miR-486-3p hsa-miR-1297 hsa-miR-3613-3p hsa-miR-558
    SwitchGear 3'UTR luciferase reporter plasmidBCL7B 3' UTR sequence
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    mitochondrion3
    nucleus3
    cytosol1

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005575cellular_component ND--

    Find genes that share ontologies with BCL7B           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for BCL7B
    Interactions:

        Search GeneGlobe Interaction Network for BCL7B

    STRING Interaction Network Preview (showing 3 interactants - click image to see more details)

    3 Interacting proteins for BCL7B (ENSP000002233684) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    HDAC2ENSP000003813314STRING: ENSP00000381331
    TERF1ENSP000002766034STRING: ENSP00000276603
    TERF2IPENSP000003000864STRING: ENSP00000300086
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008150biological_process ND--

    Find genes that share ontologies with BCL7B           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for BCL7B



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for BCL7B gene (3 alternative transcripts): 
    NM_001197244.1  NM_001707.3  NM_138707.1  

    Unigene Cluster for BCL7B:

    B-cell CLL/lymphoma 7B
    Hs.647051  [show with all ESTs]
    Unigene Representative Sequence: NM_001707
    14 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000486818(uc010lbf.2) ENST00000493671 ENST00000223368(uc003tyf.2 uc003tyg.2)
    ENST00000411832 ENST00000482231(uc003tye.2) ENST00000454871 ENST00000463858
    ENST00000448175 ENST00000455335 ENST00000493679 ENST00000464288 ENST00000416906
    ENST00000493592 ENST00000481667
    miRNA
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    hsa-miR-26a-2* hsa-miR-607 hsa-miR-148b hsa-miR-4318 hsa-miR-486-3p hsa-miR-1297 hsa-miR-3613-3p hsa-miR-558
    SwitchGear 3'UTR luciferase reporter plasmidBCL7B 3' UTR sequence
    Inhib. RNA
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    Additional mRNA sequence: 

    AJ223979.1 AK290091.1 BC000956.2 BC001967.2 BC009548.1 NR_036682.1 X89985.1 

    18 DOTS entries:

    DT.316994  DT.100796404  DT.95337407  DT.99937132  DT.100796406  DT.100796401  DT.100040319  DT.100763178 
    DT.100796402  DT.100796403  DT.95237244  DT.100796405  DT.100796410  DT.100796412  DT.100796414  DT.102821902 
    DT.97769613  DT.100779218 

    Selected AceView cDNA sequences (see all 307):

    BU195096 AI468129 BM695121 AA326474 BQ008758 CR612621 AW771450 BQ020464 
    AW328570 BI824795 BI916352 AI031873 BI752779 AA905077 CR604024 BM923951 
    AI282698 CR620291 AA877249 BC009548 CR614287 BM128063 CR598138 BU145459 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for BCL7B (see all 10)    About this scheme

    ExUns: 1a · 1b ^ 2a · 2b · 2c ^ 3 ^ 4 ^ 5a · 5b ^ 6a · 6b · 6c ^ 7 ^ 8a · 8b · 8c · 8d · 8e · 8f · 8g · 8h · 8i
    SP1:              -     -     -                             -           -                                                               
    SP2:              -     -     -     -                       -           -                                                               
    SP3:                                -                       -           -                                                               
    SP4:              -     -     -     -                       -     -     -                                                               
    SP5:              -     -     -     -           -     -     -           -                                                               


    ECgene alternative splicing isoforms for BCL7B

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    BCL7B expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TTGAATTGAA
    BCL7B Expression
    About this image


    BCL7B expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     
     Bone (Muscoskeletal System)
             Bone Marrow
    BCL7B Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    BCL7B Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.647051

    UniProtKB/Swiss-Prot: BCL7B_HUMAN, Q9BQE9
    Tissue specificity: Ubiquitous

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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for BCL7B gene from Selected species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Bcl7b1 , 5 B cell CLL/lymphoma 7B1, 5 88.45(n)1
    96.04(a)1
      5 (75.04 cM)5
    120541  NM_009745.21  NP_033875.21 
     1351682835 
    chicken
    (Gallus gallus)
    Aves BCL7B1 B-cell CLL/lymphoma 7B 78.88(n)
    90.1(a)
      100857890  XM_004949975.1  XP_004950032.1 
    lizard
    (Anolis carolinensis)
    Reptilia BCL7B6
    B-cell CLL/lymphoma 7B
    73(a)
    1 ↔ 1
    GL343734.1(214778-219715)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia bcl7b1 B-cell CLL/lymphoma 7B 69.1(n)
    74.16(a)
      100125186  NM_001103072.1  NP_001096542.1 
    zebrafish
    (Danio rerio)
    Actinopterygii bcl7ba1 B-cell CLL/lymphoma 7B, a 65.64(n)
    68.21(a)
      406444  NM_213165.1  NP_998330.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta BCL7-like6
    BCL7-like
    36(a)
    1 → many
    X(9250667-9252627)
    worm
    (Caenorhabditis elegans)
    Secernentea C28H8.16
    Protein C28H8.1 (C28H8.1) mRNA, complete cds
    32(a)
    1 → many
    III(5926060-5927166) WBGene00016192


    ENSEMBL Gene Tree for BCL7B (if available)
    TreeFam Gene Tree for BCL7B (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for BCL7B gene
    BCL7C2  BCL7A2  
    2 SIMAP similar genes for BCL7B using alignment to 4 protein entries:     BCL7B_HUMAN (see all proteins):
    BCL7C    BCL7A

    Find genes that share paralogs with BCL7B           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for BCL7B (see all 452)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 7 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs561119291,2
    C--72288257(+) AAAAA-/AA/AAA
            
    GAGTT
    5 -- int1 cds11NA 2
    rs801639921,2
    C--72288258(+) AAAAAA/GAGTTA 3 -- int10--------
    rs113356761,2
    C--72964975(+) TTTTT-/TGTTTG 3 -- int1 trp31Minor allele frequency- T:0.00CSA 2
    rs1489202401,2
    --76475226(+) TTGCTG/TGTCAG 3 -- ds50010--------
    rs1157746941,2
    C,F--76475313(+) ACTGCG/ACCTGG 3 -- ds50011Minor allele frequency- A:0.02WA 118
    rs2004601971,2
    --76475358(+) TAGAT-/AGAG  
            
    ATAGG
    3 -- ds50010--------
    rs1481014951,2
    --76475514(+) GGGAGA/GCTAGA 3 -- ds50010--------
    rs1886328251,2
    --76475525(+) AATCAC/TTGTCA 3 -- ds50010--------
    rs1419125101,2
    --76475576(+) GCCCAC/GAGTGA 3 -- ds50010--------
    rs1932731411,2
    --76475612(+) CCACCA/CCGGCC 3 -- ds50010--------

    HapMap Linkage Disequilibrium report for BCL7B (72950683 - 72972332 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 3 variations for BCL7B:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv831028CNV Loss17160897
    nsv888369CNV Loss21882294
    dgv7325n71CNV Loss21882294

    Site Specific Mutation Identification with PCR Assays
    Search QIAGEN SeqTarget long-range PCR primers for resequencing BCL7B
    DNA2.0 Custom Variant and Variant Library Synthesis for BCL7B

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

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    OMIM gene information: 605846    OMIM disorders: --

    UniProtKB/Swiss-Prot: BCL7B_HUMAN, Q9BQE9
  • Note=BCL7B is located in the Williams-Beuren syndrome (WBS) critical region. WBS results from a
    hemizygous deletion of several genes on chromosome 7q11.23, thought to arise as a consequence of unequal crossing
    over between highly homologous low-copy repeat sequences flanking the deleted region. Haploinsufficiency of BCL7B
    may be the cause of certain cardiovascular and musculo-skeletal abnormalities observed in the disease

  • 4 diseases for BCL7B:    
    About MalaCards
    small intestine adenocarcinoma    supravalvular aortic stenosis    burkitt's lymphoma    williams-beuren syndrome

    1 disease from the University of Copenhagen DISEASES database for BCL7B:
    Supravalvular aortic stenosis

    Find genes that share disorders with BCL7B           About GenesLikeMe

    Genetic Association Database (GAD): BCL7B
    Human Genome Epidemiology (HuGE) Navigator: BCL7B (5 documents)

    Export disorders for BCL7B gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for BCL7B gene, integrated from 10 sources (see all 26):
    (articles sorted by number of sources associating them with BCL7B)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Isolation of cDNA clones coding for IgE autoantigens with serum IgE from atopic dermatitis patients. (PubMed id 9806765)1, 2, 3 Natter S.... Valenta R. (FASEB J. 1998)
    2. Molecular cloning of complex chromosomal translocation t(8;14;12)(q24.1;q32.3;q24.1) in a Burkitt lymphoma cell line defines a new gene (BCL7A) with homology to caldesmon. (PubMed id 8605326)1, 2, 3 Zani V.J.... Dyer M.J.S. (Blood 1996)
    3. The BCL7 gene family: deletion of BCL7B in Williams syndrome. (PubMed id 9931421)1, 2, 9 Jadayel D.M.... Dyer M.J.S. (Gene 1998)
    4. Meta-analysis of genome-wide association studies in &gt;80 000 subjects identifies multiple loci for C-reactive protein levels. (PubMed id 21300955)1, 4 Dehghan A....Chasman D.I. (Circulation 2011)
    5. Evaluating the discriminative power of multi-trait genetic risk scores for type 2 diabetes in a northern Swedish population. (PubMed id 20571754)1, 4 Fontaine-Bisson B....Franks P.W. (Diabetologia 2010)
    6. Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans. (PubMed id 18193044)1, 4 Kathiresan S....Orho-Melander M. (Nat. Genet. 2008)
    7. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    8. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    9. Complete physical map of the common deletion region in Williams syndrome and identification and characterization of three novel genes. (PubMed id 9860302)1, 2 Meng X....Keating M.T. (Hum. Genet. 1998)
    10. Genomic study in Mexicans identifies a new locus for triglycerides and refines European lipid loci. (PubMed id 23505323)1 Weissglas-Volkov D....Pajukanta P. (J. Med. Genet. 2013)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

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    Entrez Gene: 9275 HGNC: 1005 AceView: BCL7B Ensembl:ENSG00000106635 euGenes: HUgn9275
    ECgene: BCL7B H-InvDB: BCL7B

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for BCL7B Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for BCL7B Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for BCL7B gene:
    Search GeneIP for patents involving BCL7B

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, eBioscience, antibodies-online, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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