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Aliases for BCL2L15 Gene

Aliases for BCL2L15 Gene

  • BCL2-Like 15 2 3
  • Bcl2-L-15 3 4
  • C1orf178 3 4
  • Chromosome 1 Open Reading Frame 178 2
  • Pro-Apoptotic Bcl-2 Protein 3
  • Bcl-2-Like Protein 15 3
  • Bfk 3

External Ids for BCL2L15 Gene

Previous Symbols for BCL2L15 Gene

  • C1orf178

Summaries for BCL2L15 Gene

GeneCards Summary for BCL2L15 Gene

BCL2L15 (BCL2-Like 15) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for BCL2L15 Gene

Genomics for BCL2L15 Gene

Genomic Location for BCL2L15 Gene

Start:
113,876,814 bp from pter
End:
113,887,608 bp from pter
Size:
10,795 bases
Orientation:
Minus strand

Genomic View for BCL2L15 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for BCL2L15 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for BCL2L15 Gene

Regulatory Elements for BCL2L15 Gene

Proteins for BCL2L15 Gene

  • Protein details for BCL2L15 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q5TBC7-B2L15_HUMAN
    Recommended name:
    Bcl-2-like protein 15
    Protein Accession:
    Q5TBC7
    Secondary Accessions:
    • A0PJY6
    • A8K074
    • I6LA82

    Protein attributes for BCL2L15 Gene

    Size:
    163 amino acids
    Molecular mass:
    17725 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for BCL2L15 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for BCL2L15 Gene

Proteomics data for BCL2L15 Gene at MOPED

Post-translational modifications for BCL2L15 Gene

No Post-translational modifications

Other Protein References for BCL2L15 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for BCL2L15 Gene

Domains for BCL2L15 Gene

Protein Domains for BCL2L15 Gene

ProtoNet:
genes like me logo Genes that share domains with BCL2L15: view

No data available for Gene Families and UniProtKB/Swiss-Prot for BCL2L15 Gene

Function for BCL2L15 Gene

Gene Ontology (GO) - Molecular Function for BCL2L15 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with BCL2L15: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for BCL2L15 Gene

Localization for BCL2L15 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for BCL2L15 Gene COMPARTMENTS Subcellular localization image for BCL2L15 gene
Compartment Confidence
cytoskeleton 2
cytosol 2
nucleus 2
extracellular 1
mitochondrion 1
peroxisome 1

Gene Ontology (GO) - Cellular Components for BCL2L15 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
GO:0005829 cytosol IEA --
genes like me logo Genes that share ontologies with BCL2L15: view

Pathways for BCL2L15 Gene

SuperPathways for BCL2L15 Gene

No Data Available

Interacting Proteins for BCL2L15 Gene

Gene Ontology (GO) - Biological Process for BCL2L15 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006915 apoptotic process IEA --
genes like me logo Genes that share ontologies with BCL2L15: view

No data available for Pathways by source for BCL2L15 Gene

Compounds for BCL2L15 Gene

(3) Novoseek inferred chemical compound relationships for BCL2L15 Gene

Compound -log(P) Hits PubMed IDs
lipid 0.165 1
oxygen 0 1
calcium 0 1
genes like me logo Genes that share compounds with BCL2L15: view

Transcripts for BCL2L15 Gene

Unigene Clusters for BCL2L15 Gene

BCL2-like 15:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for BCL2L15 Gene

No ASD Table

Relevant External Links for BCL2L15 Gene

GeneLoc Exon Structure for
BCL2L15
ECgene alternative splicing isoforms for
BCL2L15

Expression for BCL2L15 Gene

mRNA expression in normal human tissues for BCL2L15 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for BCL2L15 Gene

This gene is overexpressed in Colon - Transverse (16.3), Small Intestine - Terminal Ileum (10.1), Pancreas (6.3), and Stomach (4.9).

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for BCL2L15 Gene

SOURCE GeneReport for Unigene cluster for BCL2L15 Gene Hs.123106

genes like me logo Genes that share expressions with BCL2L15: view

Orthologs for BCL2L15 Gene

This gene was present in the common ancestor of chordates.

Orthologs for BCL2L15 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia BCL2L15 36
  • 99.39 (n)
  • 98.77 (a)
BCL2L15 37
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia BCL2L15 36
  • 83.12 (n)
  • 76.87 (a)
BCL2L15 37
  • 76 (a)
OneToOne
dog
(Canis familiaris)
Mammalia BCL2L15 36
  • 86.3 (n)
  • 82.21 (a)
BCL2L15 37
  • 82 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Bcl2l15 36
  • 77.91 (n)
  • 71.17 (a)
Bcl2l15 16
Bcl2l15 37
  • 69 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia BCL2L15 37
  • 52 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Bcl2l15 36
  • 78.4 (n)
  • 70.37 (a)
chicken
(Gallus gallus)
Aves BCL2L15 36
  • 55.94 (n)
  • 44.76 (a)
BCL2L15 37
  • 36 (a)
OneToOne
Species with no ortholog for BCL2L15:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for BCL2L15 Gene

ENSEMBL:
Gene Tree for BCL2L15 (if available)
TreeFam:
Gene Tree for BCL2L15 (if available)

Paralogs for BCL2L15 Gene

Selected SIMAP similar genes for BCL2L15 Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with BCL2L15: view

No data available for Paralogs for BCL2L15 Gene

Variants for BCL2L15 Gene

Sequence variations from dbSNP and Humsavar for BCL2L15 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type MAF
VAR_031475 -

Structural Variations from Database of Genomic Variants (DGV) for BCL2L15 Gene

Variant ID Type Subtype PubMed ID
esv23869 CNV Loss 19812545

Relevant External Links for BCL2L15 Gene

HapMap Linkage Disequilibrium report
BCL2L15

Disorders for BCL2L15 Gene

(3) Novoseek inferred disease relationships for BCL2L15 Gene

Disease -log(P) Hits PubMed IDs
tumors 10.4 3
necrosis 8.96 2
ischemia 0 1
genes like me logo Genes that share disorders with BCL2L15: view

No data available for UniProtKB/Swiss-Prot for BCL2L15 Gene

Publications for BCL2L15 Gene

  1. Expression of pro-apoptotic Bfk isoforms reduces during malignant transformation in the human gastrointestinal tract. (PMID: 15961081) Dempsey C.E. … Renshaw S.A. (FEBS Lett. 2005) 2 3 4 23
  2. Bfk: a novel weakly proapoptotic member of the Bcl-2 protein family with a BH3 and a BH2 region. (PMID: 12700646) Coultas L. … Strasser A. (Cell Death Differ. 2003) 2 3
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  4. Differential expression of apoptosis-related proteins in various cellular components of ameloblastomas. (PMID: 16690252) Luo H.Y. … Li T.J. (Int J Oral Maxillofac Surg 2006) 2 3
  5. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 3 4

Products for BCL2L15 Gene

  • antibodies-online proteins for BCL2L15
  • antibodies-online antibodies for BCL2L15
  • antibodies-online kits for BCL2L15

Sources for BCL2L15 Gene

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