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BCL2L12 Gene

protein-coding   GIFtS: 54
GCID: GC19P050168

BCL2-Like 12 (Proline Rich)

  Search for BCL2L12
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
BCL2-Like 12 (Proline Rich)1 2
Bcl-2 Related Proline-Rich Protein2
Bcl-2-Like Protein 122
BPR3
Bcl2-L-123
Bcl-2-Related Proline-Rich Protein3

External Ids:    HGNC: 137871   Entrez Gene: 835962   Ensembl: ENSG000001264537   OMIM: 6108375   UniProtKB: Q9HB093   

Export aliases for BCL2L12 gene to outside databases

Previous GC identifers: GC19P050826 GC19P050536 GC19P054844 GC19P054860 GC19P046545


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for BCL2L12 Gene:
This gene encodes a member of a family of proteins containing a Bcl-2 homology domain 2 (BH2). The encoded protein
is an anti-apoptotic factor that acts as an inhibitor of caspases 3 and 7 in the cytoplasm. In the nucleus, it
binds to the p53 tumor suppressor protein, preventing its association with target genes. Overexpression of this
gene has been detected in a number of different cancers. There is a pseudogene for this gene on chromosome 3.
Alternative splicing results in multiple transcript variants. (provided by RefSeq, Sep 2013)

GeneCards Summary for BCL2L12 Gene:
BCL2L12 (BCL2-like 12 (proline rich)) is a protein-coding gene.

Gene Wiki entry for BCL2L12 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000019.9  NC_018930.2  NT_011109.17  
Regulatory elements:
   Regulatory transcription factor binding sites in the BCL2L12 gene promoter:
         STAT1   COUP-TF   p53   p300   NF-kappaB1   NF-kappaB   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 3): BCL2L12 promoter sequence
   Search Chromatin IP Primers for BCL2L12

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat BCL2L12


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19q13.3   Ensembl cytogenetic band:  19q13.33   HGNC cytogenetic band: 19q13.3

BCL2L12 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
BCL2L12 gene location

GeneLoc information about chromosome 19         GeneLoc Exon Structure

GeneLoc location for GC19P050168:  view genomic region     (about GC identifiers)

Start:
50,168,399 bp from pter      End:
50,177,173 bp from pter
Size:
8,775 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: B2L12_HUMAN, Q9HB09 (See protein sequence)
Recommended Name: Bcl-2-like protein 12  
Size: 334 amino acids; 36821 Da
Secondary accessions: Q3SY11 Q3SY13 Q96I96 Q9HB08
Alternative splicing: 3 isoforms:  Q9HB09-1   Q9HB09-2   Q9HB09-3   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for BCL2L12: NX_Q9HB09

Explore proteomics data for BCL2L12 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See BCL2L12 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (7 alternative transcripts): 
    NP_001035758.1  NP_001269445.1  NP_001269446.1  NP_001269448.1  NP_001269449.1  NP_001269450.1  NP_619580.1  

    ENSEMBL proteins: 
     ENSP00000393803   ENSP00000246785   ENSP00000469216   ENSP00000471919   ENSP00000470644  
     ENSP00000472214   ENSP00000246784  

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    ProtoNet protein and cluster: Q9HB09

    1 Blocks protein domain: IPB000712 Apoptosis regulator Bcl-2 protein

    UniProtKB/Swiss-Prot: B2L12_HUMAN, Q9HB09
    Similarity: Belongs to the Bcl-2 family


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI19376117
         
    Find genes that share ontologies with BCL2L12           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for BCL2L12:
     Increased gamma-H2AX phosphory 

         3 MGI mutant phenotypes (inferred from 1 allele(MGI details for Bcl2l12):
     cellular  homeostasis/metabolism  immune system 

    Find genes that share phenotypes with BCL2L12           About GenesLikeMe

    Animal Models:
         MGI mouse knock-out Bcl2l12/Irf3Bcl2l12/tm1Ttg for BCL2L12

       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for BCL2L12
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    miRTarBase miRNAs that target BCL2L12:
    hsa-mir-24-3p (MIRT030470), hsa-mir-18a-3p (MIRT040770), hsa-mir-455-3p (MIRT037864), hsa-mir-744-5p (MIRT037475)

    Block miRNA regulation of human, mouse, rat BCL2L12 using miScript Target Protectors
    6 qRT-PCR Assays for microRNAs that regulate BCL2L12:
    hsa-miR-182 hsa-miR-125a-5p hsa-miR-125b hsa-miR-1271 hsa-miR-96 hsa-miR-4319
    SwitchGear 3'UTR luciferase reporter plasmidBCL2L12 3' UTR sequence
    Inhib. RNA
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus2
    cytosol1
    extracellular1
    mitochondrion1
    peroxisome1

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA--

    Find genes that share ontologies with BCL2L12           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for BCL2L12
    Interactions:

        Search GeneGlobe Interaction Network for BCL2L12

    STRING Interaction Network Preview (showing 5 interactants - click image to see more details)

    Selected Interacting proteins for BCL2L12 (Q9HB091, 3 ENSP000002467854) via UniProtKB, MINT, STRING, and/or I2D (see all 6)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    UBCP0CG481, 3, ENSP000003448184EBI-6968951,EBI-3390054 I2D: score=1 STRING: ENSP00000344818
    BCL2L1Q078173, ENSP000003025644I2D: score=2 STRING: ENSP00000302564
    HSPA4P349323, ENSP000003029614I2D: score=1 STRING: ENSP00000302961
    HSPA1BP081071EBI-6969019,EBI-629985
    BCL2ENSP000003296234STRING: ENSP00000329623
    About this table

    Gene Ontology (GO): 3 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006915apoptotic process ----
    GO:0045944positive regulation of transcription from RNA polymerase II promoter IDA--
    GO:1990001inhibition of cysteine-type endopeptidase activity involved in apoptotic process IDA--

    Find genes that share ontologies with BCL2L12           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for BCL2L12 (B2L12)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for BCL2L12 gene (7 alternative transcripts): 
    NM_001040668.1  NM_001282516.1  NM_001282517.1  NM_001282519.1  NM_001282520.1  NM_001282521.1  NM_138639.1  

    Unigene Cluster for BCL2L12:

    BCL2-like 12 (proline rich)
    Hs.289052  [show with all ESTs]
    Unigene Representative Sequence: NM_138639
    9 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000441864(uc002ppb.3) ENST00000246785(uc002ppa.3) ENST00000594157
    ENST00000598979 ENST00000601168 ENST00000600947 ENST00000598306 ENST00000594793
    ENST00000246784
    miRNA
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    6 qRT-PCR Assays for microRNAs that regulate BCL2L12:
    hsa-miR-182 hsa-miR-125a-5p hsa-miR-125b hsa-miR-1271 hsa-miR-96 hsa-miR-4319
    SwitchGear 3'UTR luciferase reporter plasmidBCL2L12 3' UTR sequence
    Inhib. RNA
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    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat BCL2L12
      QuantiTect SYBR Green Assays in human, mouse, rat BCL2L12
      QuantiFast Probe-based Assays in human, mouse, rat BCL2L12

    Additional mRNA sequence: 

    BC007724.2 BC104004.1 BC104005.1 BC104006.1 FJ868798.1 FJ868799.1 FJ868800.1 FJ868801.1 
    FJ868802.1 FJ868803.1 FJ911906.1 FJ911907.1 FJ911908.1 HM347053.1 

    14 DOTS entries:

    DT.451839  DT.100845708  DT.97845292  DT.86859692  DT.75136345  DT.102841618  DT.100776091  DT.100845696 
    DT.95171837  DT.100835379  DT.453528  DT.91753634  DT.91753635  DT.91753644 

    Selected AceView cDNA sequences (see all 194):

    BU856117 BU624902 AA830756 AI498796 BQ008424 AI914387 AI457888 AI276906 
    BM478600 AA767306 AI379744 AI830915 AI143613 CA414214 BM849157 AI679907 
    BE734428 AA909889 BM767466 CA418711 BM974452 AI679400 AA236858 NM_138639 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for BCL2L12 (see all 6)    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3a · 3b ^ 4 ^ 5 ^ 6 ^ 7a · 7b · 7c
    SP1:                                                                  
    SP2:                                                                  
    SP3:                                            -                     
    SP4:                    -     -                                       
    SP5:                                      -     -                     


    ECgene alternative splicing isoforms for BCL2L12

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    BCL2L12 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TCCCTGCCCT
    BCL2L12 Expression
    About this image


    BCL2L12 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 4) fully expand
     
     Testis (Reproductive System)
             Secondary Spermatocyte Seminiferous Tubules
     
     Gonad
             Secondary Spermatocyte Seminiferous Tubules
     
     Eye (Sensory Organs)
             Retina
     
     Thymus (Hematopoietic System)
    BCL2L12 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    BCL2L12 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.289052

    UniProtKB/Swiss-Prot: B2L12_HUMAN, Q9HB09
    Tissue specificity: Expressed mainly in breast, thymus, prostate, fetal liver, colon, placenta, pancreas, small
    intestine, spinal cord, kidney, and bone marrow and to a lesser extent in many other tissues. Isoform 2 is
    primarily expressed in skeletal muscle

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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for BCL2L12 gene from Selected species (see all 7)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Bcl2l121 , 5 BCL2-like 12 (proline rich)1, 5 80.53(n)1
    84.8(a)1
      7 (29.07 cM)5
    757361  NM_029410.31  NP_083686.11 
     449912225 
    lizard
    (Anolis carolinensis)
    Reptilia BCL2L126
    BCL2-like 12 (proline rich)
    31(a)
    1 ↔ 1
    6(79782525-79794185)
    zebrafish
    (Danio rerio)
    Actinopterygii BCL2L126
    BCL2-like 12 (proline rich)
    24(a)
    1 ↔ 1
    3(32708905-32720350) ENSDARG00000090625


    ENSEMBL Gene Tree for BCL2L12 (if available)
    TreeFam Gene Tree for BCL2L12 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for BCL2L12 gene

    Find genes that share paralogs with BCL2L12           About GenesLikeMe


    1 Pseudogenes.org Pseudogene for BCL2L12
    PGOHUM00000238190


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for BCL2L12 (see all 128)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 19 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1904273171,2
    --50171225(+) AGACAC/TGGGGT 2 -- int10--------
    rs1812479041,2
    C--50171511(+) CCATGC/GCCGGC 2 -- int10--------
    rs1867043661,2
    --50171647(+) CACTGC/TGCCTG 2 -- int10--------
    rs129863011,2
    C,H--50171681(+) CCAGTC/ATGAGG 2 -- int16Minor allele frequency- A:0.00NS EA NA 522
    rs1413612531,2
    C--50171790(+) GCTTGA/GTTGCT 2 -- int10--------
    rs753683651,2
    C,F--50171947(+) GAGGCC/TGAGGC 2 -- int11Minor allele frequency- T:0.50WA 2
    rs1896231861,2
    --50172043(+) GTTGGA/GGGAAG 2 -- int10--------
    rs2018565941,2
    --50172058(+) GAATCC/TGTAAG 2 -- int10--------
    rs1807379841,2
    C--50172059(+) AATCCA/GTAAGT 2 -- int10--------
    rs1998371231,2
    C--50172125(+) CAGACG/TTCTAT 4 V F mis10--------

    HapMap Linkage Disequilibrium report for BCL2L12 (50168399 - 50177173 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 9 variations for BCL2L12:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv912269CNV Loss21882294
    dgv3972n71CNV Loss21882294
    nsv828578CNV Loss20364138
    nsv833864CNV Gain17160897
    nsv470150CNV Gain18288195
    nsv817854CNV Gain17921354
    nsv9739CNV Gain+Loss18304495
    nsv833865CNV Gain+Loss17160897
    nsv469715CNV Complex16826518

    Site Specific Mutation Identification with PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 610837    OMIM disorders: --


    Find genes that share disorders with BCL2L12           About GenesLikeMe

    2 Novoseek inferred disease relationships for BCL2L12 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    breast cancer 24.9 6 12783122 (2), 16895478 (2), 15493871 (1)
    cancer 0 1 15493871 (1)

    Genetic Association Database (GAD): BCL2L12
    Human Genome Epidemiology (HuGE) Navigator: BCL2L12 (5 documents)

    Export disorders for BCL2L12 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for BCL2L12 gene, integrated from 10 sources (see all 59):
    (articles sorted by number of sources associating them with BCL2L12)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Molecular cloning, physical mapping, and expression analysis of a novel gene, BCL2L12, encoding a proline-rich protein with a highly conserved BH2 domain of the Bcl-2 family. (PubMed id 11401436)1, 2, 9 Scorilas A....Diamandis E.P. (Genomics 2001)
    2. Germline variation in apoptosis pathway genes and risk of non-Hodgkin's lymphoma. (PubMed id 20855536)1, 4 Kelly J.L....Cerhan J.R. (amp 2010)
    3. Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)1, 4 Bailey S.D....Anand S. (Diabetes Care 2010)
    4. An unappreciated role for RNA surveillance. (PubMed id 14759258)1, 2 Hillman R.T.... Brenner S.E. (Genome Biol. 2004)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    6. What drives intense apoptosis resistance and propensity for necrosis in glioblastoma? A role for Bcl2L12 as a multifunctional cell death regulator. (PubMed id 18769159)1, 9 Stegh A.H....DePinho R.A. (Cell Cycle 2008)
    7. Expression of BCL2L12, a new member of apoptosis-related genes, in breast tumors. (PubMed id 12783122)1, 9 Talieri M....Scorilas A. (Thromb. Haemost. 2003)
    8. Expression analysis of BCL2L12, a new member of apoptosis-related genes, in colon cancer. (PubMed id 15493871)1, 9 Mathioudaki K....Talieri M. (Biol. Chem. 2004)
    9. Molecular analysis and prognostic impact of the novel apoptotic gene BCL2L12 in gastric cancer. (PubMed id 19903463)1, 9 Florou D....Scorilas A. (Biochem. Biophys. Res. Commun. 2010)
    10. Quantitative expression analysis and prognostic significance of the novel apoptosis-related gene BCL2L12 in colon cancer. (PubMed id 18844453)1, 9 Kontos C.K....Scorilas A. (Biol. Chem. 2008)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Disorders
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      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 83596 HGNC: 13787 AceView: BCL2L12 Ensembl:ENSG00000126453 euGenes: HUgn83596
    ECgene: BCL2L12 H-InvDB: BCL2L12

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for BCL2L12 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for BCL2L12 Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for BCL2L12 gene:
    Search GeneIP for patents involving BCL2L12

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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