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BCL2L10 Gene

protein-coding   GIFtS: 57
GCID: GC15M052401

BCL2-Like 10 (Apoptosis Facilitator)

  See BCL2L10-related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
BCL2-Like 10 (Apoptosis Facilitator)1 2     Diva2
Anti-Apoptotic Protein NrH2 3     Bcl-2-Like Protein 102
Apoptosis Regulator Bcl-B2 3     bcl2-L-102
BCL-B2     BCLB3
Boo2     Bcl2-L-103

External Ids:    HGNC: 9931   Entrez Gene: 100172   Ensembl: ENSG000001378757   OMIM: 6069105   UniProtKB: Q9HD363   

Export aliases for BCL2L10 gene to outside databases

Previous GC identifers: GC15M047960 GC15M045448 GC15M049980 GC15M050117 GC15M050189 GC15M029232


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for BCL2L10 Gene:
The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or
homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular
activities. The protein encoded by this gene contains conserved BH4, BH1 and BH2 domains. This protein can
interact with other members of BCL-2 protein family including BCL2, BCL2L1/BCL-X(L), and BAX. Overexpression of
this gene has been shown to suppress cell apoptosis possibly through the prevention of cytochrome C release from
the mitochondria, and thus activating caspase-3 activation. The mouse counterpart of this protein is found to
interact with Apaf1 and forms a protein complex with Caspase 9, which suggests the involvement of this protein in
APAF1 and CASPASE 9 related apoptotic pathway. (provided by RefSeq, Jul 2008)

GeneCards Summary for BCL2L10 Gene:
BCL2L10 (BCL2-like 10 (apoptosis facilitator)) is a protein-coding gene. Diseases associated with BCL2L10 include non-hodgkin lymphoma, and acute myeloid leukemia.

UniProtKB/Swiss-Prot: B2L10_HUMAN, Q9HD36
Function: Promotes cell survival. Suppresses apoptosis induced by BAX but not BAK

Gene Wiki entry for BCL2L10 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000015.9  NT_010194.18  NC_018926.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the BCL2L10 gene promoter:
         E2F-3a   E2F-4   E2F-5   GATA-3   Lmo2   E2F-2   C/EBPalpha   E2F   E2F-1   ZID   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidBCL2L10 promoter sequence
   Search Chromatin IP Primers for BCL2L10

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat BCL2L10


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 15q21   Ensembl cytogenetic band:  15q21.2   HGNC cytogenetic band: 15q21

BCL2L10 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
BCL2L10 gene location

GeneLoc information about chromosome 15         GeneLoc Exon Structure

GeneLoc location for GC15M052401:  view genomic region     (about GC identifiers)

Start:
52,401,460 bp from pter      End:
52,404,972 bp from pter
Size:
3,513 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: B2L10_HUMAN, Q9HD36 (See protein sequence)
Recommended Name: Bcl-2-like protein 10  
Size: 194 amino acids; 21973 Da
Subunit: Binds to Bcl-2, Bcl-X and BAX. Interacts with APAF1
Sequence caution: Sequence=AAG00503.1; Type=Erroneous initiation; Sequence=AAH93826.1; Type=Erroneous initiation;
Sequence=AAH93828.1; Type=Erroneous initiation; Sequence=AAI04443.1; Type=Erroneous initiation;
Sequence=AAI04444.1; Type=Erroneous initiation; Sequence=AAK48715.1; Type=Erroneous initiation;
1 PDB 3D structure from and Proteopedia for BCL2L10:
4B4S (3D)    
Secondary accessions: Q3SX80 Q52LQ9 Q8TCS9

Explore the universe of human proteins at neXtProt for BCL2L10: NX_Q9HD36

Explore proteomics data for BCL2L10 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys109, Lys110
  • Modification sites at PhosphoSitePlus

  • See BCL2L10 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_065129.1  
    ENSEMBL proteins: 
     ENSP00000260442   ENSP00000453562  

    BCL2L10 Human Recombinant Protein Products:

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    5 InterPro protein domains:
     IPR026312 BCL2L10
     IPR020717 Bcl2_BH1_motif_CS
     IPR020726 Bcl2_BH2_motif_CS
     IPR002475 Bcl2-like
     IPR026298 Blc2_fam

    Graphical View of Domain Structure for InterPro Entry Q9HD36

    ProtoNet protein and cluster: Q9HD36

    1 Blocks protein domain: IPB000712 Apoptosis regulator Bcl-2 protein

    UniProtKB/Swiss-Prot: B2L10_HUMAN, Q9HD36
    Similarity: Belongs to the Bcl-2 family


    Find genes that share domains with BCL2L10           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: B2L10_HUMAN, Q9HD36
    Function: Promotes cell survival. Suppresses apoptosis induced by BAX but not BAK

         Gene Ontology (GO): 3 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI11278245
    GO:0042803protein homodimerization activity IBA--
    GO:0046982protein heterodimerization activity IBA--
         
    Find genes that share ontologies with BCL2L10           About GenesLikeMe


    Phenotypes:
         1 MGI mutant phenotype (inferred from 1 allele(MGI details for Bcl2l10):
     normal 

    Find genes that share phenotypes with BCL2L10           About GenesLikeMe

    Animal Models:
         MGI mouse knock-out Bcl2l10tm1Pmc for BCL2L10

       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for BCL2L10
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       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for BCL2L10

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    1 qRT-PCR Assays for microRNA that regulate BCL2L10:
    hsa-miR-4277
    SwitchGear 3'UTR luciferase reporter plasmidBCL2L10 3' UTR sequence
    Inhib. RNA
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    B2L10_HUMAN, Q9HD36: Mitochondrion. Nucleus membrane
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    mitochondrion5
    nucleus5
    cytosol4
    golgi apparatus1
    peroxisome1

    Gene Ontology (GO): Selected cellular component terms (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005739mitochondrion IDA11278245
    GO:0005741mitochondrial outer membrane IBA--
    GO:0005829cytosol IDA11278245
    GO:0016020membrane TAS9878060
    GO:0016021integral component of membrane IEA--

    Find genes that share ontologies with BCL2L10           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for BCL2L10 About    
    See pathways by source

    SuperPathContained pathways About
    1Apoptosis (WikiPathways)
    Apoptosis Modulation and Signaling0.38
    2Busulfan Pathway, Pharmacodynamics
    Busulfan Pathway, Pharmacodynamics
    3Apoptosis and survival Regulation of Apoptosis by Mitochondrial Proteins
    Apoptosis and survival Regulation of Apoptosis by Mitochondrial Proteins
    4Apoptosis and Autophagy
    Apoptosis and Autophagy


    Find genes that share SuperPaths with BCL2L10           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 Cell Signaling Technology (CST) Pathway for BCL2L10
        Apoptosis and Autophagy

    1 GeneGo (Thomson Reuters) Pathway for BCL2L10
        Apoptosis and survival Regulation of Apoptosis by Mitochondrial Proteins

    1 BioSystems Pathway for BCL2L10
        Apoptosis Modulation and Signaling

    1 PharmGKB Pathway for BCL2L10
        Busulfan Pathway, Pharmacodynamics

        Pathway & Disease-focused RT2 Profiler PCR Arrays including BCL2L10: 
              Apoptosis 384HT in human mouse rat
              Apoptosis in human mouse rat

    Interactions:

        GeneGlobe Interaction Network for BCL2L10

    STRING Interaction Network Preview (showing 5 interactants - click image to see 12)

    Selected Interacting proteins for BCL2L10 (Q9HD362, 3 ENSP000002604424) via UniProtKB, MINT, STRING, and/or I2D (see all 13)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    MT-RNR2Q8IVG92, 3MINT-19419 I2D: score=1 
    BAXQ078123, ENSP000002932884I2D: score=2 STRING: ENSP00000293288
    BCL2P104153, ENSP000003296234I2D: score=2 STRING: ENSP00000329623
    APAF1O147273, ENSP000003530594I2D: score=1 STRING: ENSP00000353059
    BADQ929343, ENSP000003091034I2D: score=1 STRING: ENSP00000309103
    About this table

    Gene Ontology (GO): Selected biological process terms (see all 10):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006919activation of cysteine-type endopeptidase activity involved in apoptotic process TAS9829980
    GO:0007283spermatogenesis TAS9878060
    GO:0007292female gamete generation TAS9878060
    GO:0008630intrinsic apoptotic signaling pathway in response to DNA damage IBA--
    GO:0042981regulation of apoptotic process ----

    Find genes that share ontologies with BCL2L10           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for BCL2L10 (B2L10)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for BCL2L10 gene: 
    NM_020396.2  

    Unigene Cluster for BCL2L10:

    BCL2-like 10 (apoptosis facilitator)
    Hs.283672  [show with all ESTs]
    Unigene Representative Sequence: NM_020396
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000260442(uc002abq.3) ENST00000561198
    miRNA
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    1 qRT-PCR Assays for microRNA that regulate BCL2L10:
    hsa-miR-4277
    SwitchGear 3'UTR luciferase reporter plasmidBCL2L10 3' UTR sequence
    Inhib. RNA
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    Additional mRNA sequence: 

    AF285092.1 AF326964.1 BC093826.1 BC093828.1 BC104442.1 BC104443.1 BC143227.1 

    1 DOTS entry:

    DT.108849 

    4 AceView cDNA sequences:

    AF285092 NM_020396 AF326964 AA005293 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    BCL2L10 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CTTGTTAACA
    BCL2L10 Expression
    About this image


    BCL2L10 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 2) fully expand
     
     Ovary (Reproductive System)    fully expand to see all 2 entries
             Secondary Oocyte Antral Follicle
             Secondary follicles
     
     Gonad
             Secondary Oocyte Antral Follicle
    BCL2L10 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    BCL2L10 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.283672

    UniProtKB/Swiss-Prot: B2L10_HUMAN, Q9HD36
    Tissue specificity: Widely expressed in adult tissues. Preferentially expressed in lung, liver and kidney

        Pathway & Disease-focused RT2 Profiler PCR Arrays including BCL2L10: 
              Apoptosis 384HT in human mouse rat
              Apoptosis in human mouse rat

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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of human and mouse.

    Orthologs for BCL2L10 gene from Selected species (see all 4)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Bcl2l101 , 5 Bcl2-like 101, 5 67.03(n)1
    50.81(a)1
      9 (42.30 cM)5
    120491  NM_013479.21  NP_038507.11 
     753477585 


    ENSEMBL Gene Tree for BCL2L10 (if available)
    TreeFam Gene Tree for BCL2L10 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for BCL2L10 (see all 143)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 15 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1917430551,2
    --52401407(+) CATCAA/TTTCTA 1 -- ds50010--------
    rs1847128271,2
    --52401414(+) TCTACC/TTACTC 1 -- ds50010--------
    rs1435250721,2
    --52401432(+) TGAACA/GCTTAT 1 -- ds50010--------
    rs1386926381,2
    C--52401459(+) CTAAG-/ATTTTT 1 -- ds50010--------
    rs1480372701,2
    --52401490(+) AAAACC/TTTGCA 1 -- ds50010--------
    rs762995801,2
    --52401539(+) AAACCC/TAGAAG 1 -- ds50010--------
    rs71723821,2
    C,F,H--52401638(+) TTCTAC/ATTTGG 1 -- ds50015Minor allele frequency- A:0.07NS EA WA 514
    rs1900558121,2
    --52401719(+) AGGTTC/TGCACT 1 -- ds50010--------
    rs22312971,2
    C,F,A,H--52401933(-) TTTTAC/TCTGAA 1 -- ut3125Minor allele frequency- N:0.00EA NA NS CSA WA 2564
    rs22273081,2
    C,F,H--52401951(-) TTCCCC/TCACCC 1 -- ut31 ese318Minor allele frequency- T:0.17EA NS NA 3704

    HapMap Linkage Disequilibrium report for BCL2L10 (52401460 - 52404972 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for BCL2L10:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv471244CNV Gain18288195
    nsv833005CNV Gain17160897

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing BCL2L10
    DNA2.0 Custom Variant and Variant Library Synthesis for BCL2L10

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 606910    OMIM disorders: --

    2 diseases for BCL2L10:    
    About MalaCards
    non-hodgkin lymphoma    acute myeloid leukemia


    Find genes that share disorders with BCL2L10           About GenesLikeMe

    Genetic Association Database (GAD): BCL2L10
    Human Genome Epidemiology (HuGE) Navigator: BCL2L10 (7 documents)

    Export disorders for BCL2L10 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for BCL2L10 gene, integrated from 10 sources (see all 39):
    (articles sorted by number of sources associating them with BCL2L10)
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    1. Bcl2-L-10, a novel anti-apoptotic member of the Bcl-2 family, blocks apoptosis in the mitochondria death pathway but not in the death receptor pathway. (PubMed id 11689480)1, 2, 9 Zhang H.... De Geyter C. (Hum. Mol. Genet. 2001)
    2. Boo, a novel negative regulator of cell death, interacts with Apaf-1. (PubMed id 9878060)1, 3, 9 Song Q....Vincenz C. (EMBO J. 1999)
    3. Bcl-B, a novel Bcl-2 family member that differentially binds and regulates Bax and Bak. (PubMed id 11278245)1, 2, 9 Ke N.... Reed J.C. (J. Biol. Chem. 2001)
    4. Germline variation in apoptosis pathway genes and risk of non-Hodgkin's lymphoma. (PubMed id 20855536)1, 4 Kelly J.L....Cerhan J.R. (amp 2010)
    5. Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)1, 4 Bailey S.D....Anand S. (Diabetes Care 2010)
    6. Association between genetic variants in VEGF, ERCC3 and occupational benzene haematotoxicity. (PubMed id 19773279)1, 4 Hosgood H.D....Lan Q. (Occup Environ Med 2009)
    7. Common genetic variants in candidate genes and risk of familial lymphoid malignancies. (PubMed id 19573080)1, 4 Liang X.S....Goldin L.R. (Br. J. Haematol. 2009)
    8. Risk of non-Hodgkin lymphoma associated with germline variation in genes that regulate the cell cycle, apoptosis, and lymphocyte development. (PubMed id 19336552)1, 4 Morton L.M....Hartge P. (amp 2009)
    9. NrH, a human homologue of Nr-13 associates with Bcl-Xs and is an inhibitor of apoptosis. (PubMed id 11593390)1, 2 Aouacheria A....Gillet G. (Oncogene 2001)
    10. Diva, a Bcl-2 homologue that binds directly to Apaf-1 and induces BH3-independent cell death. (PubMed id 9829980)1, 3 Inohara N....NA_A+ez G. (J. Biol. Chem. 1998)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 10017 HGNC: 993 AceView: BCL2L10 Ensembl:ENSG00000137875 euGenes: HUgn10017
    ECgene: BCL2L10 H-InvDB: BCL2L10

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for BCL2L10 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for BCL2L10 Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for BCL2L10 gene:
    Search GeneIP for patents involving BCL2L10

    GeneCards and IP:
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