BCL2A1 Gene
protein-coding GIFtS: 63
GCID: GC15M080256
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BCL2-related protein A1 (Previous symbol: HBPA1)
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Aliases for BCL2A1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb) About This Section
|
| Aliases |
|---|
| BCL2-Related Protein A11 2 | | Hemopoietic-Specific Early Response Protein2 3 | | BCL2L51 2 3 | | Protein BFL-12 3 | | BFL11 2 3 | | Bcl-2-Related Protein A12 | | GRS1 2 3 | | Bcl2-L-53 | | HBPA11 2 3 | | Hematopoietic BCL2-Related Protein A12 | | ACC-11 2 | | Bcl2-L-53 | | ACC-21 2 | | Protein GRS3 | | Bcl-2-Like Protein 52 3 | | |
Export aliases for BCL2A1 gene to outside databasesPrevious GC identifers: GC15M076214 GC15M073410 GC15M077829 GC15M077969 GC15M078040 GC15M057011 |
Summaries for BCL2A1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| Entrez Gene summary for BCL2A1: This gene encodes a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and actas anti- and pro-apoptotic regulators that are involved in a wide variety of cellular activities such as embryonicdevelopment, homeostasis and tumorigenesis. The protein encoded by this gene is able to reduce the release ofpro-apoptotic cytochrome c from mitochondria and block caspase activation. This gene is a direct transcription targetof NF-kappa B in response to inflammatory mediators, and is up-regulated by different extracellular signals, such asgranulocyte-macrophage colony-stimulating factor (GM-CSF), CD40, phorbol ester and inflammatory cytokine TNF and IL-1,which suggests a cytoprotective function that is essential for lymphocyte activation as well as cell survival.Alternatively spliced transcript variants encoding different isoforms have been found for this gene. (provided byRefSeq, Jul 2008) UniProtKB/Swiss-Prot: B2LA1_HUMAN, Q16548Function: Retards apoptosis induced by IL-3 deprivation. May function in the response of hemopoietic cells to externalsignals and in maintaining endothelial survival during infection (By similarity) Gene Wiki entry for BCL2A1 (BCL2-related protein A1)
|
Genomic Views for BCL2A1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics) About This Section
| RefSeq DNA sequence:- NC_000015.9 NC_018926.1 NT_010194.17
Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the BCL2A1 gene promoter: CREB c-Fos TBP C/EBPbeta AP-1 ATF-2 deltaCREB c-Jun Other transcription factors
Search SABiosciences Chromatin IP Primers for BCL2A1
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat BCL2A1 |
Genomic Location: Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 15q24.3 Ensembl cytogenetic band: 15q25.1 HGNC cytogenetic band: 15q24.3BCL2A1 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different)

GeneLoc information about chromosome 15 GeneLoc Exon Structure GeneLoc location for GC15M080256: view genomic region
(about GC identifiers)
Start:
|
80,253,231 bp from pter |
End:
|
80,263,788 bp from pter |
Size:
|
10,558 bases |
Orientation:
|
minus strand |
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Proteins for BCL2A1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
| UniProtKB/Swiss-Prot: B2LA1_HUMAN, Q16548 (See
protein sequence)Recommended Name: Bcl-2-related protein A1 Size: 175 amino acids; 20132 Da
Subunit: Interacts directly with BAK1, BID, BMF and BBC3 (By similarity). Interacts directly with BCL2L11/BIM.Interacts with BAX isoform Sigma. Interacts directly with PMAIP1. Interacts with BOP/C22orf29
Subcellular location: Cytoplasm
3 PDB 3D structures from and Proteopedia for BCL2A1:2VM6 (3D)
  3I1H (3D)
  3MQP (3D)
 
Secondary accessions: Q6FGZ4 Q6FH19 Q86W13 Q99524Alternative splicing: 2 isoforms: Q16548-1 Q16548-2 Explore the universe of human proteins at neXtProt for BCL2A1: NX_Q16548
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q16548 BCL2A1 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_001108207.1 NP_004040.1 ENSEMBL proteins: ENSP00000267953 ENSP00000335250 Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005737 | cytoplasm |
IEA | -- |
BCL2A1 for ontologies About GeneDecksing
BCL2A1 Antibody Products: Assay Products for BCL2A1: |
Protein
Domains / Families for BCL2A1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
BCL2A1 for domains About GeneDecksing
5 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q16548ProtoNet protein and cluster: Q16548 1 Blocks protein family: IPB000712 Apoptosis regulator Bcl-2 protein
UniProtKB/Swiss-Prot: B2LA1_HUMAN, Q16548Similarity: Belongs to the Bcl-2 family |
Function for BCL2A1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
| Function Summary: UniProtKB/Swiss-Prot: B2LA1_HUMAN, Q16548Function: Retards apoptosis induced by IL-3 deprivation. May function in the response of hemopoietic cells to externalsignals and in maintaining endothelial survival during infection (By similarity)Induction: By phorbol ester and inflammatory cytokines, such as TNF or IL1B/interleukin-1 beta, but not by growthfactors Genatlas biochemistry entry for BCL2A1:BCL2 related gene,isolated from a fetal liver,predominantly expressed in bone marrow,involved in regulation ofapoptosis,murine A1 homolog
Clone Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for BCL2A1 (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for BCL2A1 (see all 2) OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
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In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for BCL2A1 |
Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table
BCL2A1 for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for BCL2A1: Animal Models: Mouse knock-outs for BCL2A1: Bcl2a1atm1Orlf Bcl2a1atm1Sen 3 MGI mutant phenotypes (inferred from 2 alleles ) (MGI details for Bcl2a1a):
BCL2A1 for phenotypes About GeneDecksing
|
Pathways & Interactions for BCL2A1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
| Unified GeneCards pathways - 5/8 super-pathways (see all 8) About this table  See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Apoptosis and survival_Anti-apoptotic TNFs/NF-kB/Bcl-2 pathway | | | 2 | BAFF in B-Cell Signaling | | | 3 | BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members | | | 4 | Apoptosis and Autophagy | | | 5 | Apoptosis Modulation and Signaling | |
Pathway sources See GeneCards unified pathways Show all pathways
3 EMD Millipore Pathways for BCL2A1 1 Downloadable PowerPoint Slide of QIAGEN Pathway Central Maps for BCL2A1 1
Cell Signaling Technology (CST) Pathway for BCL2A1 3 GeneGo (Thomson Reuters) Pathways for BCL2A1 3 BioSystems Pathways for BCL2A1 
BCL2A1 for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for BCL2A1
STRING Interaction
Network Preview (showing 5 interactants - click image to see 15)
 5/20 Interacting proteins for BCL2A1 (Q165482, 3 ENSP000002679534) via UniProtKB, MINT, STRING, and/or I2D (see all 20)About this table
Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006915 | apoptotic process |
IEA | -- | | GO:0043066 | negative regulation of apoptotic process |
IEA | -- |
BCL2A1 for ontologies About GeneDecksing
|
Drugs & Compounds for BCL2A1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
BCL2A1 for compounds About GeneDecksing
Browse Tocris compounds for BCL2A1 10/20 Novoseek chemical compound relationships for BCL2A1 gene (see all 20) About this table
| Compound |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| mifepristone |
67.8 |
9 |
15736964 (2), 9880517 (1), 19048455 (1), 15564339 (1) (see all 6) |
| dexamethasone |
63.1 |
13 |
12657604 (2), 18515658 (2), 16543270 (1), 19048455 (1) (see all 6) |
| corticosterone |
56.4 |
16 |
9626555 (4), 19261881 (2), 8274434 (1), 19202080 (1) (see all 5) |
| dexamethasone sodium phosphate |
56.3 |
1 |
17307208 (1) |
| steroid |
54.7 |
6 |
15358110 (1), 17116691 (1), 15736964 (1), 8190832 (1) (see all 6) |
| molybdate |
37.2 |
2 |
8838140 (1) |
| retinoid |
35 |
3 |
15774497 (1), 15016838 (1) |
| clenbuterol |
33.5 |
1 |
17307208 (1) |
| progesterone |
29 |
12 |
15736964 (2), 15774497 (1), 18215457 (1), 17571860 (1) (see all 8) |
| acth |
12.9 |
1 |
9629309 (1) |
Search CenterWatch for drugs/clinical trials and news about BCL2A1 / B2LA1 
|
Transcripts for BCL2A1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
) About This Section
| REFSEQ mRNAs for BCL2A1 gene (2 alternative transcripts): NM_001114735.1 NM_004049.3 Unigene Cluster for BCL2A1: BCL2-related protein A1 Hs.227817 [show with all ESTs]Unigene Representative Sequence: AK3040262 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000267953(uc002bfd.4 uc002bfc.4) ENST00000335661
Clone Products: |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for BCL2A1 (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for BCL2A1 (see all 2) OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): BCL2A1 (NM_004049) | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for BCL2A1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat BCL2A1  |
Additional cDNA sequence: AK304026.1 AL110097.1 AY234180.1 BC016281.1 BT007103.1 CR541937.1 CR541962.1 U27467.1 U29680.1 Y09397.1 3 DOTS entries: DT.111931 DT.97836197 DT.95264169 24/66 AceView cDNA sequences (see all 66): BC016281 CR541937 AI202978 R29263 U27467 BT007103 BG198875 AI654170 CD640421 AA255905 CD641380 CD638983 BU532682 CD640333 D20314 BF677029 AV712760 AA459491 AL110097 AI470744 CD522849 Y09397 AA256018 BG216703 GeneLoc Exon Structure
2 Alternative Splicing Database (ASD) splice patterns (SP) for BCL2A1 About this scheme
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3a | · | 3b | |
| SP1: | |   | |   | |   | |   | |   | |
| SP2: | |   | |   | - |   | |   | |   |
ECgene alternative splicing isoforms for BCL2A1
|
Expression for BCL2A1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| BCL2A1 expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this imageBioGPS CGAP TAG: TAATGAATAA
About this image See BCL2A1 Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for BCL2A1
SOURCE GeneReport for Unigene cluster: Hs.227817 UniProtKB/Swiss-Prot: B2LA1_HUMAN, Q16548Tissue specificity: Seems to be restricted to the hematopoietic compartment. Expressed in peripheral blood, spleen, andbone marrow, at moderate levels in lung, small intestine and testis, at a minimal levels in other tissues. Also foundin vascular smooth muscle cells and hematopoietic malignancies SABiosciences Expression via Pathway-Focused PCR Arrays including BCL2A1 (see all 8):
Primer Products: |  | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for BCL2A1 Browse OriGene validated miRNA SYBR primer pairs
| |  | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat BCL2A1 | |  | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat BCL2A1 | |  | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat BCL2A1 | In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for BCL2A1 |
Orthologs for BCL2A1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for BCL2A1 gene from 2/8 species (see all 8) About this table
| Organism |
Taxonomic classification |
Gene |
Description |
Human Similarity |
Orthology Type |
Details |
mouse (Mus musculus) |
Mammalia |
Bcl2a1a5 Bcl2a1d1 |
B cell leukemia/lymphoma 2 related protein A1a5 B cell leukemia/lymphoma 2 related protein A1d1 |
78.49(n)1 72.67(a)1 |
  |
9 (47.24 cM)5 120471 NM_007536.21 NP_031562.11 889569205 |
chicken (Gallus gallus) |
Aves |
BCL2A11 |
BCL2-related protein A1 |
60.89(n) 46.24(a) |
  |
395673 NM_204866.1 NP_990197.1 |
ENSEMBL Gene Tree for BCL2A1 (if available) TreeFam Gene Tree for BCL2A1 (if available)  |
Paralogs for BCL2A1 gene(Paralogs according to
1HomoloGene, 2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68) About This Section
| -- |
Genomic Variants for BCL2A1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical significance | Chr 15 pos | Sequence | # | AA Chg | Type | More | # | Allele freq | Pop | Total sample | More |
|---|
HapMap Linkage Disequilibrium report for BCL2A1 (80253231 - 80263788 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV) variations for BCL2A1: -- Human Gene Mutation Database (HGMD): BCL2A1
 | SABiosciences Cancer Mutation PCR Assays |
|  | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing BCL2A1 |
|
Disorders
/ Diseases for BCL2A1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
BCL2A1 for disorders About GeneDecksing
OMIM gene information: 601056
OMIM disorders: --
20/35 diseases for BCL2A1 (see all 35): About MalaCardshuman granulocytic anaplasmosis non-hodgkin lymphoma cortisol resistance glucocorticoid resistance systemic lupus erythematosus lymphocytic leukemia lupus erythematosus hodgkin's lymphoma atopic dermatitis chronic lymphocytic leukemia somatization disorder leukemia/lymphoma kaposi's sarcoma urethritis stomach cancer colon cancer dermatitis leukemia osteosarcoma breast cancer
10/20 Novoseek disease relationships for BCL2A1 gene (see all 20) About this table
Human Genome Epidemiology (HuGE) Navigator: BCL2A1 (16 documents) Export disorders for BCL2A1 gene to outside databases
|
Publications for BCL2A1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for BCL2A1 gene, integrated from 9 sources (see all 233): (articles sorted by number of sources associating them with BCL2A1) | |  | Utopia: connect your pdf to the dynamic world of online information |
- A novel Bcl-2 related gene, Bfl-1, is overexpressed in stomach cancer and preferentially expressed in bone marrow. (PubMed id 7478596)1, 2, 9 Choi S.S.... Shin H.-S. (1995)
- Identification of a polymorphic gene, BCL2A1, encoding two novel hematopoietic lineage-specific minor histocompatibility antigens. (PubMed id 12771180)1, 3, 9 Akatsuka Y....Takahashi T. (2003)
- Completing the family portrait of the anti-apoptotic Bcl-2 proteins: crystal structure of human Bfl-1 in complex with Bim. (PubMed id 18812174)1, 2, 9 Herman M.D....Nordlund P. (2008)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- GRS, a novel member of the Bcl-2 gene family, is highly expressed in multiple cancer cell lines and in normal leukocytes. (PubMed id 9050999)1, 2 Kenny J.J....Lang J.C. (1997)
- Cloning of human Bcl-2 homologue: inflammatory cytokines induce human A1 in cultured endothelial cells. (PubMed id 8605321)1, 2 Karsan A.... Harlan J.M. (1996)
- The complete sequence of the coding region of the ATM gene reveals similarity to cell cycle regulators in different species. (PubMed id 8589678)1, 3 Savitsky K.... Rotman G. (1995)
- C-terminal residues regulate localization and functio n of the antiapoptotic protein Bfl-1. (PubMed id 19759007)1, 9 Brien G....Bonnefoy-Berard N. (2009)
- Defective ubiquitin-mediated degradation of antiapopt otic Bfl-1 predisposes to lymphoma. (PubMed id 20185581)1, 9 Fan G....GAclinas C. (2010)
- Upregulation of bfl-1 is a potential mechanism of chemoresistance in B-cell chronic lymphocytic leukaemia. (PubMed id 17726463)1, 9 Olsson A....Osorio L.M. (2007)
|
External Searches for BCL2A1 gene
(in PubMed,
OMIM, and NCBI Bookshelf) About This Section
|
|
Genome Databases showing BCL2A1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing BCL2A1 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing BCL2A1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
|
|
About This Section
| Patent Information for BCL2A1 gene: Search GeneIP for patents involving BCL2A1
GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products for BCL2A1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences), In Situ Hybridization Assays from Advanced Cell Diagnostics About This Section
|
 | |
 | |
 |
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variant library, vector shuttling | | OriGene Custom Antibody Services for BCL2A1 | | OriGene Custom Protein Services for BCL2A1 | | OriGene Custom Immunoassay Development | | |
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| | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat BCL2A1 | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing BCL2A1 | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat BCL2A1 | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat BCL2A1 | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat BCL2A1 | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat BCL2A1 |
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| Antibodies & Assays for BCL2A1  |
| | | Search Tocris compounds for BCL2A1 |
| |  |  |  |  | | | | | Recombinant Protein for BCL2A1 |
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 | | BCL2A1 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for BCL2A1 |
|  |  |  | | | ThermoFisher Antibody for BCL2A1 |
| | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat BCL2A1 |
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