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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

BCL2 Gene

protein-coding GIFtS: 74
GCID: GC18M060763

B-cell CLL/lymphoma 2

Explore 371 diseases affiliated with
BCL2 via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
B-Cell CLL/Lymphoma 2¹ ²
Bcl-2¹ ²
PPP1R50¹ ²
Apoptosis Regulator Bcl-2²
Protein Phosphatase 1, Regulatory Subunit 50²

External Ids:	HGNC: 990¹	Entrez Gene: 596²	Ensembl: ENSG00000171791⁷	OMIM: 151430⁵	UniProtKB: P10415³

Export aliases for BCL2 gene to outside databases

Previous GC identifers: GC18M060629 GC18M058939 GC18M058941 GC18M057487

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for BCL2:

This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such

as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus,

is thought to be the cause of follicular lymphoma. Two transcript variants, produced by alternate splicing, differ in

their C-terminal ends. (provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: BCL2_HUMAN, P10415

Function: Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural

cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback

loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the

mitochondria and/or by binding to the apoptosis-activating factor (APAF-1)

summary for BCL2:

Bcl-2 family proteins regulate and contribute to programmed cell death or apoptosis. It is a large protein

family and all members contain at least one of four BH (bcl-2 homology) domains. Certain members such as

Bcl-2, Bcl-xl and Mcl1 are anti-apoptotic, whilst others are pro-apoptotic. The pro-apoptotic group of Bcl-2

proteins can be further sub-divided into the structurally diverse 'BH3' only proteins (e.g. Bid, Noxa, Puma

and Bad) and the multidomain proteins that share BH1 to 3 (e.g. Bax and Bak). Most Bcl-2 family members

contain a C-terminal transmembrane domain that functions to target these proteins to the outer mitochondrial

and other intracellular membranes.

Gene Wiki entry for BCL2 (Bcl-2)

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000018.9 NC_018929.1 NT_025028.14

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the BCL2 gene promoter:
AP-2alpha isoform 3 AP-2alpha isoform 4 AP-2alpha isoform 2 AP-2alpha AP-2alphaA
Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 5): BCL2 promoter sequence

Search SABiosciences Chromatin IP Primers for BCL2

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat BCL2

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 18q21.3 Ensembl cytogenetic band: 18q21.33 HGNC cytogenetic band: 18q21.3

BCL2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
BCL2 gene location

GeneLoc information about chromosome 18 GeneLoc Exon Structure

GeneLoc location for GC18M060763: view genomic region (about GC identifiers)

Start:	60,790,579 bp from pter	End:	60,987,361 bp from pter
Size:	196,783 bases	Orientation:	minus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: BCL2_HUMAN, P10415 (See protein sequence)

Recommended Name: Apoptosis regulator Bcl-2

Size: 239 amino acids; 26266 Da

Subunit: Forms homodimers, and heterodimers with BAX, BAD, BAK and Bcl-X(L). Heterodimerization with BAX requires

intact BH1 and BH2 motifs, and is necessary for anti-apoptotic activity (By similarity). Interacts with EI24 (By

similarity). Also interacts with APAF1, BBC3, BCL2L1, BNIPL, MRPL41 and TP53BP2. Binding to FKBP8 seems to target BCL2

to the mitochondria and probably interferes with the binding of BCL2 to its targets. Interacts with BAG1 in an

ATP-dependent manner. Interacts with RAF1 (the 'Ser-338' and 'Ser-339' phosphorylated form). Interacts (via the BH4

domain) with EGLN3; the interaction prevents the formation of the BAX-BCL2 complex and inhibits the anti-apoptotic

activity of BCL2. Interacts with G0S2; this interaction also prevents the formation of the anti-apoptotic BAX-BCL2

complex. Interacts with BOP

Subcellular location: Mitochondrion outer membrane; Single-pass membrane protein. Nucleus membrane; Single-pass

membrane protein. Endoplasmic reticulum membrane; Single-pass membrane protein

6/9 PDB 3D structures from and Proteopedia for BCL2 (see all 9):

1G5M (3D)

1GJH (3D)

1YSW (3D)

2O21 (3D)

2O22 (3D)

2O2F (3D)

Secondary accessions: P10416 Q13842 Q16197

Alternative splicing: 2 isoforms: P10415-1 P10415-2

Explore the universe of human proteins at neXtProt for BCL2: NX_P10415

Post-translational modifications:

Phosphorylation/dephosphorylation on Ser-70 regulates anti-apoptotic activity. Growth factor-stimulated phosphorylation

on Ser-70 by PKC is required for the anti-apoptosis activity and occurs during the G2/M phase of the cell cycle. In

the absence of growth factors, BCL2 appears to be phosphorylated by other protein kinases such as ERKs and

stress-activated kinases. Phosphorylated by MAPK8/JNK1 at Thr-69, Ser-70 and Ser-87, wich stimulates

starvation-induced autophagy. Dephosphorylated by protein phosphatase 2A (PP2A) (By similarity)¹

Proteolytically cleaved by caspases during apoptosis. The cleaved protein, lacking the BH4 motif, has pro-apoptotic

activity, causes the release of cytochrome c into the cytosol promoting further caspase activity¹

Monoubiquitinated by PARK2, leading to increase its stability¹

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_P10415

BCL2 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins (2 alternative transcripts):

NP_000624.2 NP_000648.2

ENSEMBL proteins:

ENSP00000381185 ENSP00000329623 ENSP00000466417 ENSP00000404214

Reactome Protein details: P10415
Human Recombinant Protein Products:

	Browse Purified and Recombinant Proteins at EMD Millipore
	R&D Systems Recombinant & Natural Proteins for BCL2 (Bcl-2)
	Browse recombinant and purified proteins available from Enzo Life Sciences
	OriGene Purified Protein: BCL2 OriGene Protein Over-expression Lysate (see all 2): BCL2 OriGene Custom Protein Services for BCL2
	GenScript Custom Purified and Recombinant Proteins Services for BCL2
	Novus Biologicals BCL2 Proteins
	Browse Sino Biological Recombinant Proteins
	ProSpec Recombinant Protein for BCL2
	Browse Proteins at Uscn

Gene Ontology (GO): 5/15 cellular component terms (GO ID links to tree view) (see all 15): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005622	intracellular	--	--
GO:0005624	membrane fraction	--	--
GO:0005634	nucleus	IDA	7896880
GO:0005737	cytoplasm	IDA	7546744
GO:0005739	mitochondrion	IDA	7896880

BCL2 for ontologies About GeneDecksing

BCL2 Antibody Products:

	EMD Millipore Mono- and Polyclonal Antibodies for the study of BCL2
	R&D Systems Antibodies for BCL2 (Bcl-2)
	Cell Signaling Technology (CST) Antibodies for BCL2 (Bcl-2)
	OriGene Antibodies (see all 4): BCL2 OriGene Custom Antibody Services for BCL2
	GenScript Superior Antibodies for BCL2
	Novus Biologicals BCL2 Antibodies
	Abcam antibodies for BCL2
	Browse Antibodies at Uscn
	ThermoFisher Antibody for BCL2

Assay Products for BCL2:

	Browse Kits and Assays available from EMD Millipore
	OriGene Custom Immunoassay Development Browse OriGene Fluorogenic Cell Assay Kits
	R&D Systems ELISAs for BCL2 (Bcl-2) (see all)
	GenScript Custom Assay Services for BCL2
	Cell Signaling Technology (CST) Sandwich ELISA Kits for BCL2 (Bcl-2)
	Enzo Life Sciences assays for BCL2
	Browse ELISAs and CLIAs at Uscn

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

BCL2 for domains About GeneDecksing

5/9 InterPro domains/families (see all 9):

IPR020731 Bcl2_BH4_motif_CS

IPR020728 Bcl2_BH3_motif_CS

IPR003093 Bcl2_BH4

IPR002475 Bcl2-like

IPR026298 Blc2_fam

Graphical View of Domain Structure for InterPro Entry P10415

ProtoNet protein and cluster: P10415

2 Blocks protein families:

IPB000712 Apoptosis regulator Bcl-2 protein

IPB003093 Apoptosis regulator Bcl-2 protein

UniProtKB/Swiss-Prot: BCL2_HUMAN, P10415

Domain: The BH4 motif is required for anti-apoptotic activity and for interaction with RAF1 and EGLN3

Similarity: Belongs to the Bcl-2 family

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Function Summary:

UniProtKB/Swiss-Prot: BCL2_HUMAN, P10415

Function: Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural

cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback

loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the

mitochondria and/or by binding to the apoptosis-activating factor (APAF-1)

Genatlas biochemistry entry for BCL2:

inner mitochondrial membrane protein,C elegans CED9 homolog,key regulator of apoptosis by inhibiting the release of

cytochrome from the mitochondrial and by protecting a wide variety of cells including B cells and neuronal

cells,activated by nerve growth factor,mediated by the p42/p44 MAPK cascade,inhibited by phosphorylation mediated by

microtubule-damaging drugs through JNK- and cAMP-dependent protein kinases ; interacting with SMN1,also modulating

CDK2 activation during thymocyte apoptosis,overexpressed in endometrial carcinoma

miRNA Products:		miRTarBase miRNAs that target BCL2: hsa-mir-630 (MIRT005578), hsa-mir-34c-5p (MIRT003979), hsa-mir-16 (MIRT001800), hsa-let-7a (MIRT000418), hsa-mir-181d (MIRT003498), hsa-mir-29b (MIRT003290), hsa-mir-34b (MIRT000065), hsa-mir-181c (MIRT003499), hsa-mir-15b (MIRT000978), hsa-mir-20a (MIRT003011), hsa-mir-15a (MIRT000815), hsa-mir-451 (MIRT005744), hsa-mir-181a (MIRT003501), hsa-mir-204 (MIRT000192), hsa-mir-17 (MIRT003014), hsa-mir-29a (MIRT003291), hsa-mir-21 (MIRT000159), hsa-mir-29c (MIRT003289), hsa-mir-34a (MIRT002298), hsa-mir-195 (MIRT005362), hsa-mir-181b (MIRT003500), hsa-mir-192 (MIRT004844), hsa-mir-153 (MIRT000290)

		OriGene 3'-UTR Clone (see all 2): BCL2 Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat BCL2
		8/117 QIAGEN miScript miRNA Assays for microRNAs that regulate BCL2 (see all 117):
		hsa-miR-323-3p hsa-miR-607 hsa-miR-1307 hsa-miR-15a hsa-miR-605 hsa-miR-632 hsa-miR-30d hsa-miR-550a*

		Browse SwitchGear 3'UTR luciferase reporter plasmids

Inhib. RNA Products:		EMD Millipore RNAi Products for the Analysis of BCL2 Gene knock-down
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for BCL2 (see all 7) OriGene shRNA RFP: BCL2 OriGene siRNA: BCL2
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat BCL2

Gene Editing
Products:

DNA2.0 Custom Protein Engineering Service for BCL2

Clone Products:		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for BCL2 (see all 5) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for BCL2 (see all 3) OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector (see all 2): BCL2 (NM_000633)
		Sino Biological Human cDNA Clone for BCL2
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for BCL2
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat BCL2

Cell Line Products:		GenScript Custom overexpressing Cell Line Services for BCL2
		Search LifeMap BioReagents cell lines for BCL2

In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for BCL2

Gene Ontology (GO): 5/13 molecular function terms (GO ID links to tree view) (see all 13): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0002020	protease binding	IDA	10620603
GO:0005515	protein binding	IPI	--
GO:0008134	transcription factor binding	IEA	--
GO:0015267	channel activity	IDA	9219694
GO:0019903	protein phosphatase binding	--	--

BCL2 for ontologies About GeneDecksing

1 GenomeRNAi human phenotype for BCL2:

Increased gamma-H2AX phosphory

Animal Models:
Mouse knock-outs for BCL2: Bcl2^tm1Dlo Bcl2^tm1Sjk Bcl2^tm1Tsu
15/21 MGI mutant phenotypes (inferred from 9 alleles) (MGI details for Bcl2) (see all 21):

adipose tissue	cardiovascular system	cellular	craniofacial	digestive/alimentary
endocrine/exocrine gland	growth/size	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism
immune system	integument	mortality/aging	muscle	nervous system

BCL2 for phenotypes About GeneDecksing

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Unified GeneCards pathways - 5/74 super-pathways (see all 74) About this table

See pathways by source

Super-pathway

contained gene-specific pathways

PEDF Induced Signaling

8/11 pathways (see all 11)
PEDF Induced Signaling	1.00	STAT3 Pathway	0.47
MIF Mediated Glucocorticoid Regulation	0.73	Endothelin-1 Signaling Pathway	0.44
MIF Regulation of Innate Immune Cells	0.71	NFAT Signaling and Lymphocyte Interactions	0.37
IL-6 Pathway	0.61	PGC1Alpha Pathway	0.33

Development HGF signaling pathway

Apoptosis and survival_Anti-apoptotic action of membrane-bound ESR1	0.24	Neurotrophin signaling pathway	0.20
Apoptosis and survival Anti-apoptotic action of membrane-bound ESR1	0.24	Apoptosis and survival_Anti-apoptotic action of nuclear ESR1 and ESR2	0.15
Apoptosis and survival_Role of CDK5 in neuronal death and survival	0.24	Apoptosis and survival Anti-apoptotic action of nuclear ESR1 and ESR2	0.15
Apoptosis and survival Role of CDK5 in neuronal death and survival	0.24

BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members

BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members	1.00	Apoptosis and survival Regulation of Apoptosis by Mitochondrial Proteins	0.24
Activation of BH3-only proteins	0.30	Intrinsic Pathway for Apoptosis	0.23
Apoptosis and survival_Regulation of Apoptosis by Mitochondrial Proteins	0.24	Activation of BAD and translocation to mitochondria	0.15

TGF-Beta Pathway

TGF-Beta Pathway	1.00	JNK Pathway	0.50
MAPK Family Pathway	0.60	Regulation of eIF4 and p70S6K	0.43
JAK-STAT Pathway	0.57	SOCS Pathway	0.29

TWEAK Pathway

HIV-1 Nef- Negative effector of Fas and TNF-alpha	0.42	Apoptotic Pathways Triggered By HIV1	0.37
Apoptosis and survival_TNFR1 signaling pathway	0.40	Apoptosis through Death Receptors	0.32
Apoptosis and survival TNFR1 signaling pathway	0.40

Pathway sources
See GeneCards unified pathways
Show all pathways

5/16 EMD Millipore Pathways for BCL2 (see all 16)

	Apoptosis and survival Role of CDK5 in neuronal death and survival
	Development EPO-induced Jak-STAT pathway
	Apoptosis and survival FAS signaling cascades
	Apoptosis and survival Anti-apoptotic action of nuclear ESR1 and ESR2
	Apoptosis and survival TNFR1 signaling pathway

3 R&D Systems Pathways for BCL2

	IL-7 Signaling and its Primary Biological Effects in Different Immune Cell Types
	Apoptosis Signaling Pathways
	IL-15 Signaling and its Primary Biological Effects in Different Immune Cell Types

5/48 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for BCL2 (see all 48)

	FLT3 Signaling
	14-3-3 Induced Apoptosis
	IL-4 Pathway
	Mitochondrial Apoptosis
	Molecular Mechanisms of Cancer

1 Cell Signaling Technology (CST) Pathway for BCL2

Apoptosis and Autophagy

1 Tocris Bioscience Pathway for BCL2

Apoptosis Pathway

5/15 GeneGo (Thomson Reuters) Pathways for BCL2 (see all 15)

	Apoptosis and survival BAD phosphorylation
	Transcription P53 signaling pathway
	Apoptosis and survival Anti-apoptotic action of membrane-bound ESR1
	Apoptosis and survival Anti-apoptotic action of nuclear ESR1 and ESR2
	Apoptosis and survival FAS signaling cascades

5/30 BioSystems Pathways for BCL2 (see all 30)

	FAS pathway and Stress induction of HSP regulation
	DNA damage response (only ATM dependent)
	Focal Adhesion
	Senescence and Autophagy
	Integrated Breast Cancer Pathway

5/10 Reactome Pathways for BCL2 (see all 10)

	Activation of BH3-only proteins
	Activation of BAD and translocation to mitochondria
	The NLRP1 inflammasome
	Inflammasomes
	Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways

2 PharmGKB Pathways for BCL2

	Busulfan Pathway, Pharmacodynamics
	Vinka Alkaloid Pathway, Pharmacokinetics

5/12 Kegg Pathways (Kegg details for BCL2) (see all 12):

	Protein processing in endoplasmic reticulum
	Apoptosis
	Focal adhesion
	Neurotrophin signaling pathway
	Cholinergic synapse

BCL2 for pathways About GeneDecksing

Interactions:

SABiosciences Gene Network Central^TM Interacting Genes and Proteins Network for BCL2

STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

5/155 Interacting proteins for BCL2 (P10415^{1, 2, 3} ENSP00000329623⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 155)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
TP53BP2	Q13625²^,³, ENSP00000341957⁴	MINT-7235804 MINT-7235946 MINT-7235823 MINT-7236118 MINT-7236027 MINT-7236079 MINT-7236102 MINT-7236042 MINT-7236003 MINT-7235965 MINT-7235839 MINT-7236061 MINT-7235784 I2D: score=4 STRING: ENSP00000341957
AMBRA1	Q9C0C7²^,³, ENSP00000318313⁴	MINT-8182706 MINT-8182670 MINT-8182688 MINT-8182559 MINT-8182625 MINT-8174974 MINT-8182589 MINT-8182650 MINT-8182607 MINT-8182574 I2D: score=1 STRING: ENSP00000318313
BECN1	Q14457¹^,²^,³, ENSP00000355231⁴	EBI-77694,EBI-949378 MINT-8182780 MINT-4821014 MINT-4820784 MINT-8095220 MINT-8182706 MINT-7014531 MINT-7712827 MINT-8095201 I2D: score=4 STRING: ENSP00000355231
TP53	P04637¹^,²^,³, ENSP00000269305⁴	EBI-77694,EBI-366083 MINT-7291988 MINT-7292025 MINT-7291975 I2D: score=2 STRING: ENSP00000269305
BCL2L11	O43521¹^,²^,³	EBI-77694,EBI-1002160 MINT-6629252 MINT-4980319 I2D: score=12

About this table

Gene Ontology (GO): 5/154 biological process terms (GO ID links to tree view) (see all 154): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0000082	G1/S transition of mitotic cell cycle	IEA	--
GO:0000209	protein polyubiquitination	IDA	16717086
GO:0000902	cell morphogenesis	--	--
GO:0001101	response to acid	IEA	--
GO:0001503	ossification	IEA	--

BCL2 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

BCL2 for compounds About GeneDecksing

Browse Small Molecules at EMD Millipore

Enzo Life Sciences drugs & compounds for BCL2

Compounds for BCL2 available from Tocris Bioscience About this table

Compound	Action	CAS #
2,3-DCPE hydrochloride	Selectively induces cancer cell apoptosis	[418788-90-6]
Gossypol	Pro-apoptotic; downregulates Bcl-2 and Bcl-XL	[303-45-7]
HA14-1	Bcl-2 inhibitor. Induces apoptosis	[65673-63-4]

3 DrugBank Compounds for BCL2 About this table

Compound	Synonyms	CAS #	Type	Actions	PubMed Ids
Docetaxel	Docetaxel anhydrous (see all 3)	114977-28-5	target	--	15643508 15161985 15714982 15685445 17674353 15277270
Paclitaxel	7-epi-Paclitaxel (see all 5)	33069-62-4	target	inhibitor	17119350 16741658 17062688 16895478 17230521
Rasagiline	--	136236-51-6	target	activator	12057839 14555244 16148027 12043833 12200198

10/126 Novoseek chemical compound relationships for BCL2 gene (see all 126) About this table

Compound	-log (P-Val)	Hits	PubMed IDs for Articles with Shared Sentences (# sentences)
genasense	81.3	45	16584297 (3), 16564596 (3), 11751483 (2), 12393493 (1) (see all 24)
noxa	75.3	52	19372561 (3), 17018621 (3), 16673057 (2), 19540835 (2) (see all 34)
dutp	75.2	39	9212738 (1), 11920781 (1), 12210368 (1), 14761612 (1) (see all 38)
adpribose	71.7	49	12490780 (2), 11328292 (1), 11896536 (1), 18767861 (1) (see all 44)
paclitaxel	71.3	393	9716607 (8), 9699642 (7), 19671798 (6), 10097113 (6) (see all 99)
etoposide	68.8	137	10367743 (4), 8752171 (4), 9554589 (4), 8395979 (4) (see all 86)
doxorubicin	66.8	175	8781438 (6), 12579337 (3), 18498876 (3), 19818735 (3) (see all 96)
oridonin	66.3	15	17260801 (3), 15008459 (2), 15703811 (2), 16638644 (1) (see all 10)
3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide	66.1	6	12144824 (1), 15033191 (1), 18471799 (1), 15749633 (1) (see all 6)
paraffin	65.4	126	9343323 (4), 9521469 (1), 10652623 (1), 10491515 (1) (see all 99)

Search CenterWatch for drugs/clinical trials and news about BCL2

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for BCL2 gene (2 alternative transcripts):

NM_000633.2 NM_000657.2

Unigene Cluster for BCL2:

B-cell CLL/lymphoma 2

Hs.150749 [show with all ESTs]

Unigene Representative Sequence: NM_000633

5 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000398117(uc002liu.1) ENST00000333681(uc002lit.1) ENST00000590515

ENST00000589955 ENST00000444484(uc002liv.1)

miRNA Products:		OriGene 3'-UTR Clone (see all 2): BCL2 Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat BCL2
		8/117 QIAGEN miScript miRNA Assays for microRNAs that regulate BCL2 (see all 117):
		hsa-miR-323-3p hsa-miR-607 hsa-miR-1307 hsa-miR-15a hsa-miR-605 hsa-miR-632 hsa-miR-30d hsa-miR-550a*

		Browse SwitchGear 3'UTR luciferase reporter plasmids

Inhib. RNA Products:		EMD Millipore RNAi Products for the Analysis of BCL2 Gene knock-down
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for BCL2 (see all 7) OriGene shRNA RFP: BCL2 OriGene siRNA: BCL2
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat BCL2

Clone Products:		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for BCL2 (see all 5) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for BCL2 (see all 3) OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector (see all 2): BCL2 (NM_000633)
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for BCL2
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat BCL2

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for BCL2 Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay in human, mouse, rat BCL2
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat BCL2
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat BCL2

Additional cDNA sequence:

AF401211.1 BC027258.1 EU287875.1 M13994.1 M13995.1 M14745.1 X06487.1

4 DOTS entries:

DT.216205 DT.100749960 DT.86998979 DT.40316825

24/148 AceView cDNA sequences (see all 148):

AA321638 F04196 BQ224622 AF401211 BG503428 BF222234 BM986952 BM973833

AI261915 W61100 AI391699 BE503573 F07940 BE550816 AL703462 BM463468

AI627828 N42615 BC027258 BM996398 N29770 AI480094 CB118071 AI142026

GeneLoc Exon Structure

2 Alternative Splicing Database (ASD) splice patterns (SP) for BCL2 About this scheme

ExUns:	1a	·	1b	^	2	^	3
SP1:
SP2:

ECgene alternative splicing isoforms for BCL2

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

BCL2 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TGTGTGGAGA

About this image

BCL2 expression in embryonic tissues and stem cells

Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

Stem Cell Differentiation: 3 LifeMap Cells

Name

Category

PureStem™ epithelial progenitor E164 (Embryonic Progenitor Cell)

Intermediate Mesoderm, Kidney

White adipocyte-like cells (Differentiation of w...)

Brown adipocyte-like cells (Differentiation of w...)

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See BCL2 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for BCL2

SOURCE GeneReport for Unigene cluster: Hs.150749

UniProtKB/Swiss-Prot: BCL2_HUMAN, P10415

Tissue specificity: Expressed in a variety of tissues

SABiosciences Expression via Pathway-Focused PCR Arrays including BCL2 (see all 34):

Neurogenesis in human mouse rat

Lung Cancer in human mouse rat

Multiple Sclerosis in human mouse rat

Lymphoma in human mouse rat

Inflammasomes in human mouse rat

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for BCL2 Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay in human, mouse, rat BCL2
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat BCL2
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat BCL2

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for BCL2

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of chordates.

Orthologs for BCL2 gene from 3/12 species (see all 12) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
chicken (Gallus gallus)	Aves	BCL2¹	B-cell CLL/lymphoma 2	75.51(n) 77.39(a)		396282 NM_205339.1 NP_990670.1
lizard (Anolis carolinensis)	Reptilia	BCL2⁶	--	70(a)	1 ↔ 1	GL344304.1(26465-27025)
zebrafish (Danio rerio)	Actinopterygii	si:dkey-217f4.3⁶ CU695001.1⁶	--	49(a) 46(a)	1 ↔ many 1 ↔ many	2(12979720-13007658) 24(29060361-29151442)

ENSEMBL Gene Tree for BCL2 (if available)
TreeFam Gene Tree for BCL2 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for BCL2 gene

BAK1² BCL2L2² BCL2L1² BAX²

4 SIMAP similar genes for BCL2 using alignment to 3 protein entries: BCL2_HUMAN (see all proteins):

bcl-2 BCL2L2-PABPN1 BCL2L2 BCL2L1

BCL2 for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 18 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs35275357^1,2	C	--	57648853(+)	`CTAAT-/TTAG TTGTT`	1	--	int¹		0	--	--	--	--
rs188357713^1,2		--	60765382(+)	`TGGGGA/GGATGC`	1	--	int¹		0	--	--	--	--
rs4940570^1,2	C,F,	--	60765568(+)	`ATTTCA/GGGATT`	1	--	int¹		3		WA NA EA	358
rs72939458^1,2	C,F,	--	60765648(+)	`GTGAGT/AGTGAA`	1	--	int¹		2		NA EA	240
rs145228851^1,2		--	60765681(+)	`CTGTAC/TAGATG`	1	--	int¹		0	--	--	--	--
rs147654415^1,2		--	60765717(+)	`ATACTA/GCTGTT`	1	--	int¹		0	--	--	--	--
rs115857154^1,2	F,	--	60765803(+)	`TAGCTC/TGTTTG`	1	--	int¹		1		WA	118
rs192642005^1,2		--	60765810(+)	`TTTGCC/TGGCCC`	1	--	int¹		0	--	--	--	--
rs185436601^1,2		--	60765915(+)	`CCTTGA/GTGTTT`	1	--	int¹		0	--	--	--	--
rs116239407^1,2		--	60765945(+)	`CTGCCT/GGTTTC`	1	--	int¹		1		WA	118
rs149674899^1,2		--	60765998(+)	`GTGGCC/TGGCTT`	1	--	int¹		0	--	--	--	--
rs8083921^1,2	C,F,H,	--	60766102(+)	`CTCCCC/TGCTTG`	1	--	int¹		27		NS EA WA NA CSA	2663
rs62100171^1,2		--	60766103(+)	`TCCCTG/ACTTGA`	1	--	int¹		3		NA WA	122
rs145468406^1,2		--	60766140(+)	`TGGACA/GGCTGC`	1	--	int¹		0	--	--	--	--
rs148815943^1,2		--	60766229(+)	`CTCAGA/GCTGTC`	1	--	int¹		0	--	--	--	--
rs62100172^1,2	C,	--	60766296(+)	`ACCACG/AGTGGC`	1	--	int¹		4		WA NA	124
rs8099504^1,2	C,H,	--	60766333(+)	`ACTGAG/CTCCAG`	1	--	int¹		7		NS EA WA NA	752
rs188911235^1,2		--	60766456(+)	`TGTTGG/TCATCA`	1	--	int¹		0	--	--	--	--
rs116764078^1,2		--	60766534(+)	`TAAGAG/ACAAGG`	1	--	int¹		1		WA	118
rs111706702^1,2		--	60766741(+)	`ATTTTT/AAAACT`	1	--	int¹		1		CSA	2
rs145348537^1,2		--	60766828(+)	`AAAGTA/GTGCAA`	1	--	int¹		0	--	--	--	--
rs146441350^1,2		--	60766834(+)	`TGCAAA/GAGCCA`	1	--	int¹		0	--	--	--	--
rs141370747^1,2		--	60766920(+)	`GCAGCA/GTGTCC`	1	--	int¹		0	--	--	--	--
rs56032243^1,2	C,F,	--	60766927(+)	`GTCCCG/AAGTGT`	1	--	int¹		1		NA	120
rs879839^1,2	C,F,A,	--	60766933(+)	`AGTGTG/ATCACC`	1	--	int¹		17		NA EA WA CSA	753
rs4941181^1,2	C,F,A,	--	60766955(+)	`GATGTC/GCAGTG`	1	--	int¹		15		NA WA CSA EA	514
rs77187329^1,2	C,	--	60767014(+)	`GGGAGG/AGTCTG`	1	--	int¹		1		NA	2
rs8088739^1,2	C,F,A,H,	--	60767088(+)	`TCTGCT/CCTTGA`	1	--	int¹		26		EA NA NS WA CSA	2556
rs184722787^1,2		--	60767201(+)	`GGAGGC/TCAAGG`	1	--	int¹		0	--	--	--	--
rs76801627^1,2	F,	--	60767202(+)	`GAGGCC/TAAGGG`	1	--	int¹		1		NA	120
rs143623522^1,2		--	60790127(+)	`CAGTGA/GGAAAC`	1	--	ds500¹		0	--	--	--	--
rs146306001^1,2		--	60790131(+)	`GGGAAA/TCATCA`	1	--	ds500¹		0	--	--	--	--
rs181671174^1,2		--	60790172(+)	`CAAAGC/GAAGTA`	1	--	ds500¹		0	--	--	--	--
rs186010988^1,2		--	60790182(+)	`AGCTGC/TTTTGG`	1	--	ds500¹		0	--	--	--	--
rs113499998^1,2	C,	--	60790240(+)	`CCTCTC/TTTTCA`	1	--	ds500¹		1		NA	2
rs182364137^1,2		--	60790284(+)	`GATCTC/TTGGTC`	1	--	ds500¹		0	--	--	--	--
rs4987871^1,2	C,H,	--	60790398(-)	`AAGGAG/AACTCT`	1	--	ds500¹		5		NS EA	592
rs139482504^1,2		--	60790466(+)	`GAGTAG/TGGTCC`	1	--	ds500¹		0	--	--	--	--
rs113990290^1,2		--	60790483(+)	`TTTTAC/TTGGCT`	1	--	ds500¹		1		CSA	2
rs4987870^1,2	C,	--	60790687(-)	`TTAGCT/-ATAAT`	1	--	ut3¹		3		NS NA	176
rs79620975^1,2	C	--	60790687(+)	`ATTAT-/AGCTAA`	1	--	ut3¹		0	--	--	--	--
rs4987869^1,2	C,F,H,	--	60790730(-)	`ACTTTA/CCATGG`	1	--	ut3¹ ese³		10		NS EA NA	1166
rs45503395^1,2		--	60790745(-)	`AAATAC/TGGTAA`	1	--	ut3¹		0	--	--	--	--
rs182433677^1,2		--	60790786(+)	`CACCTC/GTTAAA`	1	--	ut3¹		0	--	--	--	--
rs4987868^1,2	C,F,H,	--	60790809(-)	`TGGCTC/ATTTTT`	1	--	ut3¹		5		NS NA	682
rs148888145^1,2		--	60790931(+)	`GCAAAC/TCTTGG`	1	--	ut3¹		0	--	--	--	--
rs56041624^1,2	C	--	60791050(+)	`AATGAG/AATGAG`	1	--	ut3¹		1		NA	2
rs4987867^1,2	C,F,H,	--	60791072(-)	`CTGCCG/ATGGGC`	1	--	ut3¹ ese³		6		NS EA WA	716
rs142616439^1,2		--	60791166(+)	`TTGAGC/TGAGCC`	1	--	ut3¹		0	--	--	--	--
rs187081713^1,2		--	60791215(+)	`GCTTGA/GTATGC`	1	--	ut3¹		0	--	--	--	--
rs4987866^1,2	C,H,	--	60791321(-)	`ATGCAA/GAGAAA`	1	--	ut3¹ ese³		5		NS EA	594
rs190011740^1,2		--	60791504(+)	`ACAGAA/TGTCCC`	1	--	ut3¹		0	--	--	--	--
rs4987865^1,2	C,F,H,	--	60791557(-)	`TAAATG/ATGCAG`	1	--	ut3¹		17		NS EA NA WA	1804
rs4987864^1,2	C,F,H,	--	60791734(-)	`ATTGGG/TGTCGA`	1	--	ut3¹ ese³		16		NS EA NA WA	2048
rs34811186^1,2	C,	--	60791876(+)	`AATTT-/AAAAAA`	1	--	ut3¹		1		NA	2
rs67200314^1,2	C	--	60791877(+)	`AAAAA-/ATCCCT`	1	--	ut3¹		0	--	--	--	--
rs76721111^1,2	C	--	60791887(+)	`AAAAAA/TCCCTG`	1	--	ut3¹		0	--	--	--	--
rs77530335^1,2	C,	--	60791888(+)	`AAAATC/TCCTGA`	1	--	ut3¹		0	--	--	--	--
rs140875276^1,2		--	60791908(+)	`ATTGAA/GTAACA`	1	--	ut3¹		0	--	--	--	--
rs183000521^1,2		--	60791953(+)	`AATGTA/GGAATT`	1	--	ut3¹		0	--	--	--	--
rs4987863^1,2	C,H	--	60792077(-)	`GAAAGG/TCTCGA`	1	--	ut3¹ ese³		5		NS EA	596
rs187334313^1,2		--	60792083(+)	`CTTTCC/TTGTTT`	1	--	ut3¹		0	--	--	--	--
rs142611734^1,2		--	60792144(+)	`AAAAA-/CCAGCC`	1	--	ut3¹		0	--	--	--	--
rs146086350^1,2		--	60792174(+)	`TGGAAA/TTAATT`	1	--	ut3¹		0	--	--	--	--
rs193151005^1,2		--	60792281(+)	`GGTGAA/GAGCTA`	1	--	ut3¹		0	--	--	--	--
rs185704013^1,2		--	60792300(+)	`TTGGGA/GTTGCC`	1	--	ut3¹		0	--	--	--	--
rs4987862^1,2	H	--	60792307(-)	`TAATCA/GGGGCA`	1	--	ut3¹		5		NS EA	590
rs147777348^1,2		--	60792346(+)	`CCTCTA/CGATTT`	1	--	ut3¹		0	--	--	--	--
rs141080340^1,2		--	60792347(+)	`CTCTCA/GATTTA`	1	--	ut3¹		0	--	--	--	--
rs146967889^1,2		--	60792477(+)	`GAGCTG/TTGGAG`	1	--	ut3¹		0	--	--	--	--
rs188618198^1,2		--	60792552(+)	`ATCTTA/GAGCCT`	1	--	ut3¹		0	--	--	--	--
rs4987861^1,2	C,F,H,	--	60792564(-)	`GAAAAC/TTCTGG`	1	--	ut3¹ ese³		23		NS EA NA WA CSA	2466
rs4987860^1,2	C,H	--	60792587(-)	`TCTCCG/AAAGAT`	1	--	ut3¹ ese³		5		NS EA	594
rs4987859^1,2	C,F,H,	--	60792657(-)	`CCCTCG/ACTGCA`	1	--	ut3¹ ese³		26		NS NA EA CSA WA	2870
rs41306972^1,2		--	60792675(+)	`GGGCCA/GAGGAG`	1	--	ut3¹		0	--	--	--	--
rs137980414^1,2		--	60792678(+)	`CCGAGA/GAGGTT`	1	--	ut3¹		0	--	--	--	--
rs4987858^1,2	C,F,H,	--	60792794(-)	`CTCTGT/CATGTA`	1	--	ut3¹ ese³		10		NS EA NA WA	1282
rs183691931^1,2		--	60792974(+)	`CTAACA/GTGTTT`	1	--	ut3¹		0	--	--	--	--
rs17070680^1,2		--	60793231(-)	`AGAACG/ATGGAC`	1	--	ut3¹		2		MN EA	356
rs148341476^1,2		--	60793330(+)	`CAGCAC/TAGGAT`	1	--	ut3¹		0	--	--	--	--
rs142265965^1,2		--	60793417(+)	`CAAAGG/TTCTGA`	1	--	ut3¹		0	--	--	--	--
rs4987857^1,2	C,H,	--	60793444(-)	`CCCGGC/TGGGCC`	1	--	ut3¹ ese³		6		NS EA	700
rs146379399^1,2		--	60793447(+)	`CCGCCA/GGGGAG`	1	--	ut3¹		0	--	--	--	--
rs4987856^1,2	C,F,H,	--	60793494(-)	`CTTACG/ACTCCA`	1	--	ut3¹		24		NS NA EA	2676
rs117640948^1,2	C,F,	--	60793521(+)	`GAAGAC/TCCTGA`	1	--	ut3¹		1		NA	120
rs4987855^1,2	C,F,H,	--	60793549(-)	`TCCGCG/AGGGGC`	1	--	ut3¹ ese³		18		NS NA EA	2138
rs4987854^1,2	C,F,H,	--	60793626(-)	`TGGTGG/ATTTGA`	1	--	ut3¹		12		NS NA WA	1224
rs4987853^1,2	C,F,A,H,	--	60793655(-)	`ATGGCA/GAATGA`	1	--	ut3¹		39		NS NA EA WA CSA	4100
rs188797102^1,2		--	60793696(+)	`TTTAAC/TCAAAC`	1	--	ut3¹		0	--	--	--	--
rs139528731^1,2		--	60793751(+)	`AGGGAC/TGAGGA`	1	--	ut3¹		0	--	--	--	--
rs142756703^1,2		--	60793752(+)	`GGGACA/GAGGAA`	1	--	ut3¹		0	--	--	--	--
rs181211289^1,2		--	60793822(+)	`TTGACA/GTGGAA`	1	--	ut3¹		0	--	--	--	--
rs4987852^1,2	C,F,H,	--	60793921(-)	`TTCTGA/GGAAGG`	1	--	ut3¹ ese³		18		NS NA EA	1922
rs184698169^1,2		--	60793929(+)	`GAATGC/TTTTTG`	1	--	ut3¹		0	--	--	--	--
rs4987851^1,2	C,F,H,	--	60794259(-)	`ATGGTG/AGGGAA`	1	--	ut3¹		20		NS EA NA WA	2420
rs5825508^1,2	C,F,	--	60794268(+)	`TTTTTT/-TAATG`	1	--	ut3¹ trp³		2		NA CSA	4
rs113207678^1,2		--	60794276(+)	`TTTTTA/TTAATG`	1	--	ut3¹		1		CSA	1
rs181495000^1,2		--	60794287(+)	`CCCCAA/GGATGT`	1	--	ut3¹		0	--	--	--	--
rs202112192^1,2		--	60794323(+)	`GGAAC-/TTTTTT`	1	--	ut3¹		0	--	--	--	--
rs150653783^1,2		--	60794393(+)	`TTCCAC/TAGACA`	1	--	ut3¹		0	--	--	--	--
rs139755068^1,2		--	60794479(+)	`CCTTGC/TTTTAA`	1	--	ut3¹		0	--	--	--	--
rs149940394^1,2		--	60794503(+)	`CCAAGG/TCCACA`	1	--	ut3¹		0	--	--	--	--
rs4987850^1,2	C,F,H,	--	60794516(-)	`GGCACG/ATTGGC`	1	--	ut3¹ ese³		18		NS EA NA WA CSA	1894
rs187455180^1,2		--	60794545(+)	`GGGCCA/GTGGCC`	1	--	ut3¹		0	--	--	--	--
rs145009492^1,2		--	60794566(+)	`CTCACA/GTTCCC`	1	--	ut3¹		0	--	--	--	--
rs1564483^1,2	C,F,O,A,H,	--	60794654(-)	`GCCACA/GACCCT`	1	--	ut3¹ ese³		33		MN NS EA NA WA	4958
rs4987849^1,2	C,H,	--	60794672(-)	`TTCACG/TTGGAG`	1	--	ut3¹ ese³		6		NS EA WA	706
rs3744935^1,2	C,F,H,	--	60794680(+)	`GAAAAC/TGGGCC`	1	--	ut3¹ ese³		13		EA NS NA	2472
rs144527240^1,2		--	60794769(+)	`TCAGCC/TTCCAG`	1	--	ut3¹		0	--	--	--	--
rs2078303^1,2	H	--	60794793(-)	`CAGGGC/TAGTGT`	1	--	ut3¹ ese³		4		NS EA	420
rs4987848^1,2	C,F,H,	--	60794916(-)	`AGGCCG/ACCACA`	1	--	ut3¹ ese³		5		NS NA	500
rs116117134^1,2	C,F,	--	60794953(+)	`TGATGC/TGGAAG`	1	--	ut3¹		1		WA	118
rs141174596^1,2		--	60794963(+)	`GTCACC/TGAAAT`	1	--	ut3¹		0	--	--	--	--
rs4987847^1,2	C,F,H,	--	60795021(-)	`CCAATA/GCTGGC`	1	--	ut3¹ ese³		5		NS EA	592
rs1016860^1,2	C,F,A,H,	--	60795074(-)	`CTTAAA/GCCCTG`	1	--	ut3¹		28		NA MN NS EA CSA WA	3124
rs150966214^1,2		--	60795128(+)	`CACAAC/TTGGTA`	1	--	ut3¹		0	--	--	--	--
rs4987846^1,2	C,F,H,	--	60795178(-)	`ACAGCG/AATGGG`	1	--	ut3¹ ese³		20		NS EA NA	2234
rs4987845^1,2	C,F,H,	--	60795188(-)	`ACGCCG/AAAGGA`	1	--	ut3¹ ese³		19		NS NA EA	2146
rs3744937^1,2	C,F,H,	--	60795191(+)	`TTCGGC/TGTGGA`	1	--	ut3¹ ese³		4		NS EA	420
rs191858049^1,2		--	60795230(+)	`AGTTCC/TCAACT`	1	--	ut3¹		0	--	--	--	--
rs4987844^1,2	C,H,	--	60795273(-)	`TTTGCA/CTATGA`	1	--	ut3¹ ese³		5		NS EA	580
rs41301945^1,2		--	60795318(+)	`CCCCCA/CACAGG`	1	--	ut3¹		0	--	--	--	--
rs116616724^1,2		--	60795493(+)	`CGAATA/CTATGT`	1	--	ut3¹		0	--	--	--	--
rs185016407^1,2		--	60795534(+)	`CACGAA/TGCGGT`	1	--	ut3¹		0	--	--	--	--
rs4987843^1,2	C,F,H,	--	60795541(-)	`GCCAAG/ACACCG`	1	--	ut3¹		28		NS NA EA CSA WA	2877
rs140093696^1,2		--	60795697(+)	`ATTGT-/TGTGTGT`	1	--	ut3¹		0	--	--	--	--
rs190262124^1,2		--	60795708(+)	`TGTGTG/TTGTCT`	1	--	ut3¹		0	--	--	--	--
rs200716283^1,2		--	60795836(+)	`TATTTG/TTTTGG`	1	--	ut3¹		0	--	--	--	--
rs148811059^1,2	C,F,	--	60795971(+)	`GGGGCC/TGTACA`	2	S G	mis¹		1		NA	4526
rs199540938^1,2		--	60796037(+)	`TTAGAC/GAGAGA`	1	--	int¹		0	--	--	--	--
rs4987841^1,2	C,F,H,	--	60796193(-)	`aagagG/Agtctc`	1	--	int¹		12		NS EA NA WA	1536
rs185286547^1,2		--	60796202(+)	`TTTACA/GTGCCA`	1	--	int¹		0	--	--	--	--
rs191916593^1,2		--	60796343(+)	`CCGAGA/GAGAAA`	1	--	int¹		0	--	--	--	--
rs115679407^1,2		--	60796443(+)	`TGACCG/TTCACA`	1	--	int¹		1		WA	118
rs10503077^1,2	C,F,H,	--	60796445(+)	`ACCGTC/TACACT`	1	--	int¹		18		NS EA NA CSA WA	1016
rs183301334^1,2		--	60796483(+)	`AATGTC/GTGACA`	1	--	int¹		0	--	--	--	--
rs78203204^1,2		--	60796486(+)	`GTCTGA/TCATGC`	1	--	int¹		0	--	--	--	--
rs202100912^1,2	C	--	60796525(+)	`TCTTTC/TTTTTT`	1	--	int¹		0	--	--	--	--
rs71160900^1,2	C	--	60796526(+)	`TTTTTT/-AGAGA`	1	--	int¹		1		NA	2
rs200439344^1,2		--	60796536(+)	`TTTTT-/CTTAGA`	1	--	int¹		0	--	--	--	--
rs189142916^1,2		--	60796567(+)	`GCCCAA/GGCTGC`	1	--	int¹		0	--	--	--	--
rs75012083^1,2		--	60796705(+)	`TAGGGC/TCTTAC`	1	--	int¹		0	--	--	--	--
rs142794240^1,2		--	60796795(+)	`GCATGC/TGCTTT`	1	--	int¹		0	--	--	--	--
rs114333407^1,2		--	60796891(+)	`GAATAA/GGAGAC`	1	--	int¹		1		WA	118
rs193063867^1,2		--	60796903(+)	`TTTTAA/GCAAGT`	1	--	int¹		0	--	--	--	--
rs144226228^1,2		--	60796958(+)	`CTCTGC/TTGATG`	1	--	int¹		0	--	--	--	--
rs182428037^1,2		--	60797028(+)	`TGGAGG/TGGCCA`	1	--	int¹		0	--	--	--	--
rs148708456^1,2		--	60797043(+)	`CGGCCA/TTGACT`	1	--	int¹		0	--	--	--	--
rs1982674^1,2	C,F,O,H,	--	60797061(-)	`AGAGGC/TTGGCA`	1	--	int¹		24		NS EA NA WA CSA	1030
rs141480354^1,2		--	60797076(+)	`TCAAGC/GTTCTC`	1	--	int¹		0	--	--	--	--
rs150838859^1,2		--	60797117(+)	`CTTGGG/TGGTGG`	1	--	int¹		0	--	--	--	--
rs140548131^1,2		--	60797123(+)	`GGTGGC/TTAGAC`	1	--	int¹		0	--	--	--	--
rs186765142^1,2		--	60797274(+)	`TGTAGC/TGTGTT`	1	--	int¹		0	--	--	--	--
rs191948891^1,2		--	60797300(+)	`CTCTGG/TATGGG`	1	--	int¹		0	--	--	--	--
rs76932643^1,2	F,	--	60797381(+)	`AATGAG/ATATTT`	1	--	int¹		1		EA	120
rs184202833^1,2		--	60797572(+)	`GTTGGA/GAGGGG`	1	--	int¹		0	--	--	--	--
rs189424484^1,2		--	60797587(+)	`AACAGG/TGCACA`	1	--	int¹		0	--	--	--	--
rs193173835^1,2		--	60797736(+)	`CATTGA/GTCTTT`	1	--	int¹		0	--	--	--	--
rs185082912^1,2		--	60797922(+)	`CATACG/TTTAAA`	1	--	int¹		0	--	--	--	--
rs190769989^1,2		--	60797932(+)	`AAAATC/TCATGT`	1	--	int¹		0	--	--	--	--
rs115856282^1,2	F,	--	60797942(+)	`TTTATA/TGTGTT`	1	--	int¹		1		WA	118
rs117747496^1,2	F,	--	60797989(+)	`TTTTTG/ATATAT`	1	--	int¹		1		NA	120
rs72941330^1,2	C,	--	60797992(+)	`TTGTAT/CATAAA`	1	--	int¹		2		WA NA	122
rs181845901^1,2		--	60798002(+)	`ATTCTC/TGTCTA`	1	--	int¹		0	--	--	--	--
rs1982673^1,2	C,F,A,H,	--	60798015(-)	`GCAACT/GGAACA`	1	--	int¹		24		NA EA NS CSA WA	2594
rs144406158^1,2		--	60798053(+)	`CCTCAA/GTTAAC`	1	--	int¹		0	--	--	--	--
rs113189703^1,2	C,	--	60798054(+)	`CTCAGC/TTAACC`	1	--	int¹		0	--	--	--	--
rs2332673^1,2	C,F,O,A,H,	--	60798082(+)	`CCAGAA/CATCAT`	1	--	int¹		30		NA EA NS WA CSA	2738
rs188173520^1,2		--	60798177(+)	`TAGGGC/TGAGGG`	1	--	int¹		0	--	--	--	--
rs141091302^1,2	C,	--	60798571(+)	`ATCTA-/TTGTTAAA`	1	--	int¹		0	--	--	--	--
rs17677569^1,2	C,F,H,	--	60798610(+)	`GCGAGG/CCAATA`	1	--	int¹		12		NA NS EA	1102
rs80076443^1,2		--	60798618(+)	`ATAGAC/TGTACA`	1	--	int¹		1		WA	118
rs80339992^1,2	C,F,	--	60798713(+)	`CAGGGA/GTCAGT`	1	--	int¹		5		NA WA EA	362
rs115414473^1,2	F,	--	60798936(+)	`GCTTGA/TCATTG`	1	--	int¹		1		WA	118
rs147857353^1,2		--	60799050(+)	`CTGAAA/GCCATC`	1	--	int¹		0	--	--	--	--
rs9966563^1,2	C,F,H,	--	60799111(+)	`GTTGGC/TCTGGC`	1	--	int¹		16		NS EA NA WA CSA	790
rs180706398^1,2		--	60799206(+)	`CCCCCA/TCACAA`	1	--	int¹		0	--	--	--	--
rs117221518^1,2	F,	--	60799261(+)	`ATTACG/ATAGAA`	1	--	int¹		1		EA	120
rs139748587^1,2		--	60799346(+)	`CCATCC/GCAGGG`	1	--	int¹		0	--	--	--	--
rs78541377^1,2		--	60799408(+)	`TGATAT/CTTTAT`	1	--	int¹		1		WA	118
rs112897237^1,2	C,	--	60799606(+)	`CTACTC/TAACCT`	1	--	int¹		2		NA	122
rs118076873^1,2		--	60799707(+)	`CTATAG/CGAATT`	1	--	int¹		1		NA	120
rs149947875^1,2		--	60799765(+)	`GATAAC/TACAAT`	1	--	int¹		0	--	--	--	--
rs116548391^1,2	F,	--	60799788(+)	`GTCCTT/ACTTTA`	1	--	int¹		1		WA	118
rs144903661^1,2		--	60799814(+)	`TAGGGC/TTAGAG`	1	--	int¹		0	--	--	--	--
rs149019988^1,2		--	60799837(+)	`AACCCC/GCTGGA`	1	--	int¹		0	--	--	--	--
rs142117553^1,2		--	60799851(+)	`TGGAGC/GTGGCC`	1	--	int¹		0	--	--	--	--
rs185536164^1,2		--	60799929(+)	`CTGAAA/GGCTTC`	1	--	int¹		0	--	--	--	--
rs191069111^1,2		--	60800094(+)	`GAAAAC/GCTGGG`	1	--	int¹		0	--	--	--	--
rs151167519^1,2		--	60800102(+)	`GGGTCA/GTCATG`	1	--	int¹		0	--	--	--	--
rs10503078^1,2	C,F,H,	--	60800188(+)	`TACCCG/AACTTC`	1	--	int¹		42		NS NA EA CSA WA	3801
rs114606005^1,2		--	60800205(+)	`CACAGG/ATTCAC`	1	--	int¹		1		WA	118
rs115518715^1,2	F,	--	60800212(+)	`TCACAC/TGGAAA`	1	--	int¹		1		WA	118
rs140689896^1,2		--	60800226(+)	`TGGCAC/GCGGCT`	1	--	int¹		0	--	--	--	--
rs183791081^1,2		--	60800325(+)	`AGAGGA/GTCTGA`	1	--	int¹		0	--	--	--	--
rs186697515^1,2		--	60800482(+)	`CCGGGC/TCATGG`	1	--	int¹		0	--	--	--	--
rs192480800^1,2		--	60800681(+)	`ACTACA/GCCCGG`	1	--	int¹		0	--	--	--	--
rs199809840^1,2		--	60800856(+)	`GAGAA-/TTTTTT`	1	--	int¹		0	--	--	--	--
rs1473435^1,2	C,F,H,	--	60800865(-)	`TTTTTA/TAAAAA`	1	--	int¹		13		NS EA NA WA CSA	755
rs17070714^1,2	C,F,	--	60800887(+)	`CAAGAA/GTGGAA`	1	--	int¹		4		NA WA	260
rs183364875^1,2		--	60800972(+)	`TATGCA/CCAGGT`	1	--	int¹		0	--	--	--	--
rs187717486^1,2		--	60800973(+)	`ATGCCC/GAGGTA`	1	--	int¹		0	--	--	--	--
rs145776508^1,2		--	60800996(+)	`GAGACC/TTTTTG`	1	--	int¹		0	--	--	--	--
rs138495693^1,2		--	60801025(+)	`AAAAGC/GCTTTT`	1	--	int¹		0	--	--	--	--
rs141444943^1,2		--	60801060(+)	`CTTCCA/GGTTAT`	1	--	int¹		0	--	--	--	--
rs11664592^1,2	H	--	60801119(+)	`ACCTGG/AAAACA`	1	--	int¹		4		NS EA	420
rs112388513^1,2		--	60801182(+)	`AGCATC/TAAAAG`	1	--	int¹		1		CSA	2
rs71353379^1,2	C,	--	60801198(+)	`CCCTAT/CAGTTA`	1	--	int¹		3		NA EA	242
rs113244677^1,2		--	60801301(+)	`ATACAC/TGTGCG`	1	--	int¹		1		CSA	2
rs149347914^1,2		--	60801485(+)	`TATTTC/TAATAT`	1	--	int¹		0	--	--	--	--
rs144757844^1,2		--	60801784(+)	`TGGGGA/GAATTT`	1	--	int¹		0	--	--	--	--
rs201387801^1,2	C	--	60801800(-)	`CCAGCA/CAAGCC`	1	--	int¹		0	--	--	--	--
rs115680042^1,2	F,	--	60801842(+)	`CACAGT/CCTTTG`	1	--	int¹		1		WA	118
rs138371817^1,2		--	60801907(+)	`GCCACC/TCTGTC`	1	--	int¹		0	--	--	--	--
rs139633383^1,2		--	60802157(+)	`CTCTTC/TTCTCA`	1	--	int¹		0	--	--	--	--
rs75639853^1,2	C,F,	--	60802226(+)	`CTGGGC/ATGGAA`	1	--	int¹		1		WA	118
rs117538898^1,2	F,	--	60802487(+)	`TGCCTC/GCCTCA`	1	--	int¹		1		NA	120
rs142692573^1,2		--	60802701(+)	`CTTTTA/GATGAC`	1	--	int¹		0	--	--	--	--
rs74354585^1,2		--	60802797(+)	`GATCAT/CTGGGC`	1	--	int¹		2		CSA WA	120
rs150577552^1,2		--	60802856(+)	`CTGCCC/TGTCCT`	1	--	int¹		0	--	--	--	--
rs4941183^1,2	C,F,A,H,	--	60802931(+)	`CGTCAA/GTTGTC`	1	--	int¹		24		NS EA NA WA CSA	2490
rs191481592^1,2		--	60802961(+)	`TCAATC/TGCATC`	1	--	int¹		0	--	--	--	--
rs4941184^1,2	C,F,H,	--	60802978(+)	`TTCTGG/ACCTCA`	1	--	int¹		26		NS EA NA WA CSA	1883
rs60649454^1,2	C,F,	--	60803011(+)	`TGATGC/TGTGCT`	1	--	int¹		1		WA	118
rs112088186^1,2		--	60803230(+)	`TGCCCC/TGGACA`	1	--	int¹		1		CSA	2
rs12457841^1,2	C,F,H,	--	60803244(+)	`AGACCA/TCTGAG`	1	--	int¹		11		NA WA CSA EA	374
rs8091529^1,2	C,F,H,	--	60803257(+)	`TCTTCC/TGTGAC`	1	--	int¹		5		NS EA WA	526
rs55930818^1,2	C,	--	60803327(+)	`GGCACC/TTCCTC`	1	--	int¹		2		WA NA	122
rs182156294^1,2		--	60803352(+)	`ATAAGC/TTCTCG`	1	--	int¹		0	--	--	--	--
rs188363774^1,2		--	60803508(+)	`ACTTAC/TTCCAA`	1	--	int¹		0	--	--	--	--
rs149666601^1,2		--	60803554(+)	`ACCTGC/TCCCAA`	1	--	int¹		0	--	--	--	--
rs8092560^1,2	C,F,H,	--	60803693(+)	`ATTCAT/ACAGTA`	1	--	int¹		27		NS EA NA WA CSA	2568
rs192656425^1,2		--	60803800(+)	`AAGGGC/GAGCAG`	1	--	int¹		0	--	--	--	--
rs185448822^1,2		--	60803823(+)	`AAAAAA/TGGAAA`	1	--	int¹		0	--	--	--	--
rs56087288^1,2	C,F,	--	60803872(+)	`CTACCG/AGNNNN`	1	--	int¹		6		WA NA EA	364
rs189971870^1,2		--	60803908(+)	`CTGAGA/GGCCGG`	1	--	int¹		0	--	--	--	--
rs191883771^1,2		--	60803975(+)	`TACACC/GAACTC`	1	--	int¹		0	--	--	--	--
rs146703652^1,2		--	60804102(+)	`TATAGC/TTGGAG`	1	--	int¹		0	--	--	--	--
rs116979655^1,2	F,	--	60804334(+)	`AATCAA/GATCTG`	1	--	int¹		1		NA	120
rs184745671^1,2		--	60804471(+)	`ACTTTA/CTCCAA`	1	--	int¹		0	--	--	--	--
rs12605858^1,2	C,F,H	--	60804481(+)	`aatccC/Ataggt`	1	--	int¹		5		NS EA NA	418
rs140281249^1,2		--	60804486(+)	`CTAGGG/TTGAGC`	1	--	int¹		0	--	--	--	--
rs189197801^1,2		--	60804529(+)	`ATTATA/TCGAAG`	1	--	int¹		0	--	--	--	--
rs11872297^1,2	C,H,	--	60804572(+)	`aactaT/Ctagca`	1	--	int¹		5		NS EA NA	414
rs72941346^1,2	C,F,	--	60804723(+)	`AATAGA/GTAATA`	1	--	int¹		1		NA	120
rs185868250^1,2		--	60804863(+)	`AGGACA/GCAGAG`	1	--	int¹		0	--	--	--	--
rs11874495^1,2	C,H	--	60804931(+)	`CACAGG/ATGCTT`	1	--	int¹		5		NS EA NA	418
rs189993880^1,2		--	60804962(+)	`AGCATC/TTTCCA`	1	--	int¹		0	--	--	--	--
rs899965^1,2	C,F,H,	--	60805011(-)	`AAACAC/TAGCAG`	1	--	int¹		30		NS EA NA WA CSA	2308
rs11872403^1,2	C,F,A,H,	--	60805046(+)	`ACAAGG/TGCTGC`	1	--	int¹		27		EA NA NS WA CSA	2564
rs72941348^1,2	C,F,	--	60805100(+)	`CAGCAT/CTGGTG`	1	--	int¹		1		NA	120
rs114391527^1,2		--	60805130(+)	`GAGACG/AACCAG`	1	--	int¹		1		WA	118
rs899964^1,2	C,F,O,H,	--	60805170(-)	`CTCTAT/CGTTTG`	1	--	int¹		17		NS EA NA WA CSA	794
rs181252525^1,2		--	60805179(+)	`AGACCA/TCTGGG`	1	--	int¹		0	--	--	--	--
rs720849^1,2	H,	--	60805453(-)	`CGGCCA/GCCACT`	1	--	int¹		4		NS EA	412
rs144024445^1,2		--	60805536(+)	`TCCCCC/TCTTAT`	1	--	int¹		0	--	--	--	--
rs115986418^1,2	F,	--	60805550(+)	`CGGCTC/TGGCAG`	1	--	int¹		1		WA	118
rs4987840^1,2	C	--	60805666(-)	`GGTGCG/AGGAGG`	1	--	int¹ trp³		1		NS	176
rs4987839^1,2	C,F,H,	--	60805749(-)	`CCTTCA/GGTTAT`	1	--	int¹		28		NS NA EA	3040
rs117826874^1,2		--	60805792(+)	`AGGCAC/TGGGAG`	1	--	int¹		1		NA	120
rs4987838^1,2	C,F,	--	60805799(-)	`TCTCAC/TGCTCC`	1	--	int¹		5		NS NA WA	432
rs149179077^1,2		--	60805826(+)	`TTCCTC/TCAGGC`	1	--	int¹		0	--	--	--	--
rs143398874^1,2		--	60806071(+)	`GGTGTA/GTTCTG`	1	--	int¹		0	--	--	--	--
rs191598641^1,2		--	60806095(+)	`GCTAAA/GAATGC`	1	--	int¹		0	--	--	--	--
rs181487480^1,2		--	60806097(+)	`TAAGAA/TTGCAA`	1	--	int¹		0	--	--	--	--
rs4987837^1,2	C,H	--	60806149(-)	`TTTGGG/TCTTCT`	1	--	int¹		5		NS EA	590
rs4987835^1,2	C,F,H,	--	60806215(-)	`GGCATA/GAGCCA`	1	--	int¹		19		NS EA NA WA	1548
rs148375749^1,2		--	60806228(+)	`GGGCCA/CGGGCA`	1	--	int¹		0	--	--	--	--
rs4987834^1,2	C,F,H,	--	60806253(-)	`CAGGTG/AGTTGG`	1	--	int¹		12		NS EA NA WA	938
rs71340146^1,2	C,	--	60806253(+)	`CCAACCACCTG/- CTAAT`	1	--	int¹		1		NA	2
rs4987833^1,2	C	--	60806254(-)	`CATTAGCAGGT/- GGTTG`	1	--	int¹		1		NS	164
rs4987832^1,2	C,F,H,	--	60806277(-)	`AGCTCC/TGGCTG`	1	--	int¹		6		NS EA WA	682
rs4987831^1,2	C,F,H,	--	60806372(-)	`CTTGGC/TTCTGT`	1	--	int¹		21		NS EA NA WA CSA	1319
rs4987830^1,2	C,F,	--	60806376(-)	`GGAACT/CTGGCT`	1	--	int¹		2		NS NA	290
rs4987829^1,2	C,F,H,	--	60806414(-)	`GGTGCC/TCTGCA`	1	--	int¹		17		NS EA NA WA	1610
rs186499500^1,2		--	60806418(+)	`GGGCAC/TCTGTG`	1	--	int¹		0	--	--	--	--
rs190940735^1,2		--	60806484(+)	`CTTCTA/GAAATA`	1	--	int¹		0	--	--	--	--
rs182410439^1,2		--	60806536(+)	`TTAATA/CGTTAT`	1	--	int¹		0	--	--	--	--
rs187564731^1,2		--	60806602(+)	`GTATCC/TATATG`	1	--	int¹		0	--	--	--	--
rs1531697^1,2	C,F,O,A,H,	--	60806606(-)	`AGGTCA/TTATAG`	1	--	int¹		45		NA EA NS CSA WA	4437
rs191607637^1,2		--	60806622(+)	`TCTCAC/TCTTCA`	1	--	int¹		0	--	--	--	--
rs140459966^1,2		--	60806745(+)	`GTGGCA/TTCCAT`	1	--	int¹		0	--	--	--	--
rs150398198^1,2		--	60806813(+)	`CCATTC/TGCCCA`	1	--	int¹		0	--	--	--	--
rs183007336^1,2		--	60806817(+)	`TTGCCC/TAGCAG`	1	--	int¹		0	--	--	--	--
rs4987828^1,2	C,F,H,	--	60806872(-)	`GGTGTG/ACCTTA`	1	--	int¹		26		NS EA NA WA	3068
rs4987827^1,2	C,F,H,	--	60806898(-)	`TAGGCC/ACTTTC`	1	--	int¹ trp³		21		NS EA NA WA	1718
rs56313983^1,2	C,F,	--	60806953(+)	`TAAAAC/TGAAGT`	1	--	int¹		1		NA	120
rs62100176^1,2	C,F,	--	60807049(+)	`CCCTCT/CCTTGT`	1	--	int¹		6		WA NA EA	364
rs138259755^1,2		--	60807115(+)	`AACTTA/TACACT`	1	--	int¹		0	--	--	--	--
rs79830620^1,2	F,	--	60807131(+)	`GATATT/CGTGTT`	1	--	int¹		1		WA	118
rs62100177^1,2	C,F,	--	60807192(+)	`AAAAAC/TGTAAG`	1	--	int¹		6		WA NA EA	364
rs58807419^1,2		--	60807320(+)	`CAAATC/TGAAAC`	1	--	int¹		0	--	--	--	--
rs9962963^1,2	C,F,	--	60807445(+)	`AACTGG/TTGCAG`	1	--	int¹		10		NA CSA WA EA	370
rs147259108^1,2		--	60807498(+)	`CAGAGA/TCACCA`	1	--	int¹		0	--	--	--	--
rs138121121^1,2		--	60807499(+)	`AGAGTA/CACCAC`	1	--	int¹		0	--	--	--	--
rs58158929^1,2	F,	--	60807554(+)	`TTGCAC/TGTTCA`	1	--	int¹		1		WA	118
rs111470430^1,2	C,	--	60807562(+)	`TCACAC/AGAAAA`	1	--	int¹		1		NA	2
rs28566629^1,2	C,F,	--	60807624(+)	`ATGACC/ACAAAT`	1	--	int¹		10		NA CSA WA EA	370
rs111241995^1,2		--	60807640(+)	`CTAACC/TGATGA`	1	--	int¹		1		CSA	2
rs148685662^1,2		--	60807646(+)	`GATGAA/GCAAAT`	1	--	int¹		0	--	--	--	--
rs80186902^1,2	F,	--	60807881(+)	`GGAGAC/TGGGGA`	1	--	int¹		1		EA	120
rs117729327^1,2	F,	--	60807947(+)	`TTCTGG/AAATTA`	1	--	int¹		1		NA	120
rs79220150^1,2	F,	--	60807964(+)	`GGTGAT/CGGCTG`	1	--	int¹		1		WA	118
rs7240319^1,2	C,F,H,	--	60807985(+)	`TGAATA/GTGCTA`	1	--	int¹		11		NS EA NA	1432
rs73965839^1,2	C,	--	60808076(+)	`NNNNAC/TGACAT`	1	--	int¹		3		WA NA	240
rs142080782^1,2		--	60808284(+)	`GGGTCA/GGATGC`	1	--	int¹		0	--	--	--	--
rs8098586^1,2	C,F,H,	--	60808340(+)	`CTTCAC/GCCCTG`	1	--	int¹

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BCL2 Gene

B-cell CLL/lymphoma 2

Aliases
for BCL2 gene

Summaries
for BCL2 gene

Genomic Views
for BCL2 gene

Proteins
for BCL2 gene

Protein Domains /
Families
for BCL2 gene

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for BCL2 gene

Pathways & Interactions
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Drugs & Compounds
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Transcripts
for BCL2 gene

Expression
for BCL2 gene

Orthologs
for BCL2 gene

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for BCL2 gene

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for BCL2 gene

Advanced Search

Export list of displayed genes

BCL2 Gene

B-cell CLL/lymphoma 2

Aliasesfor BCL2 gene

Summariesfor BCL2 gene

Genomic Viewsfor BCL2 gene

Proteinsfor BCL2 gene

Protein Domains /Familiesfor BCL2 gene

Functionfor BCL2 gene

Pathways & Interactionsfor BCL2 gene

Drugs & Compoundsfor BCL2 gene

Transcriptsfor BCL2 gene

Expression for BCL2 gene

Orthologsfor BCL2 gene

Paralogsfor BCL2 gene

Genomic Variantsfor BCL2 gene

Aliases
for BCL2 gene

Summaries
for BCL2 gene

Genomic Views
for BCL2 gene

Proteins
for BCL2 gene

Protein Domains /
Families
for BCL2 gene

Function
for BCL2 gene

Pathways & Interactions
for BCL2 gene

Drugs & Compounds
for BCL2 gene

Transcripts
for BCL2 gene

Expression
for BCL2 gene

Orthologs
for BCL2 gene

Paralogs
for BCL2 gene

Genomic Variants
for BCL2 gene