BCL10 Gene
protein-coding GIFtS: 65
GCID: GC01M085731
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|
B-cell CLL/lymphoma 10
| |
Aliases
for BCL10 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| B-Cell CLL/Lymphoma 101 2 3 | | HCLAP1 | | CIPER1 2 3 | | B-Cell Lymphoma/Leukemia 102 | | CLAP1 2 3 | | CARD Containing Molecule Enhancing NF-KB2 | | C-E101 | | CARD-Containing Apoptotic Signaling Protein2 | | ME101 | | CARD-Containing Proapoptotic Protein2 | | CARMEN1 2 | | Caspase-Recruiting Domain-Containing Protein2 | | Cellular Homolog Of VCARMEN2 3 | | Cellular-E103 | | Mammalian CARD-Containing Adapter Molecule E102 3 | | Bcl-103 | | CCARMEN1 | | Cellular-E103 | | CARD-Containing Molecule Enhancing NF-Kappa-B2 3 | | CARD-Like Apoptotic Protein3 | | CED-3/ICH-1 Prodomain Homologous E10-Like Regulator2 3 | | |
Export aliases for BCL10 gene to outside databasesPrevious GC identifers: GC01M086131 GC01M084873 GC01M085020 GC01M085154 GC01M085443 GC01M083842 |
Summaries
for BCL10 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for BCL10:
This gene was identified by its translocation in a case of mucosa-associated lymphoid tissue (MALT) lymphoma. Theprotein encoded by this gene contains a caspase recruitment domain (CARD), and has been shown to induce apoptosis andto activate NF-kappaB. This protein is reported to interact with other CARD domain containing proteins includingCARD9, 10, 11 and 14, which are thought to function as upstream regulators in NF-kappaB signaling. This protein isfound to form a complex with MALT1, a protein encoded by another gene known to be translocated in MALT lymphoma. MALT1and this protein are thought to synergize in the activation of NF-kappaB, and the deregulation of either of them maycontribute to the same pathogenetic process that leads to the malignancy. (provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: BCL10_HUMAN, O95999Function: Promotes apoptosis, pro-caspase-9 maturation and activation of NF-kappa-B via NIK and IKK. May be an adapterprotein between upstream TNFR1-TRADD-RIP complex and the downstream NIK-IKK-IKAP complex. Is a substrate for MALT1
Gene Wiki entry for BCL10
|
Genomic Views
for BCL10 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000001.10 NC_018912.1 NT_032977.9
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the BCL10 gene promoter:
AP-1 ATF-2 RelA POU3F2 (N-Oct-5a) POU3F2 (N-Oct-5b) HNF-3beta POU3F2 FAC1 STAT3 c-Jun
Other transcription factors
Search SABiosciences Chromatin IP Primers for BCL10
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat BCL10 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 1p22 Ensembl cytogenetic band: 1p22.3 HGNC cytogenetic band: 1p22BCL10 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 1 GeneLoc Exon Structure GeneLoc location for GC01M085731: view genomic region
(about GC identifiers)
Start:
|
85,731,459 bp from pter |
End:
|
85,743,771 bp from pter |
Size:
|
12,313 bases |
Orientation:
|
minus strand |
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Proteins
for BCL10 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: BCL10_HUMAN, O95999 (See
protein sequence)Recommended Name: B-cell lymphoma/leukemia 10 Size: 233 amino acids; 26252 Da
Subunit: Found in a membrane raft complex, at least composed of BCL10, CARD11, DPP4 and IKBKB. Self-associates byCARD-CARD interaction and forms a tight complex with MALT1. Interacts with other CARD-proteins such as CARD9, CARD10,CARD11 and CARD14. Binds caspase-9 with its C-terminal domain. Interacts with TRAF2 and BIRC2/c-IAP2. Interacts withPELI2 and SOCS3; these interactions may be mutually exclusive (By similarity)
Subcellular location: Cytoplasm, perinuclear region. Membrane raft. Note=Appears to have a perinuclear, compact andfilamentous pattern of expression. Also found in the nucleus of several types of tumor cells. Colocalized with DPP4 inmembrane rafts
Secondary accessions: Q5VUF1Explore the universe of human proteins at neXtProt for BCL10: NX_O95999
Post-translational modifications:
Phosphorylated. Phosphorylation results in dissociation from TRAF2 and binding to BIRC2/c-IAP2. Phosphorylated byIKBKB/IKKB1
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_O95999
BCL10 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_003912.1
ENSEMBL proteins: ENSP00000359612 ENSP00000271015 Reactome Protein details: O95999
Human Recombinant Protein Products:
Gene Ontology (GO): 5/12 cellular component terms (GO ID links to tree view) (see all 12): About this table
BCL10 for ontologies About GeneDecksing
BCL10 Antibody Products:
Assay Products for BCL10: |
Protein
Domains /
Families
for BCL10 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
BCL10 for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry O95999ProtoNet protein and cluster: O95999 1 Blocks protein family: IPB001315 CARD interaction domain
UniProtKB/Swiss-Prot: BCL10_HUMAN, O95999Similarity: Contains 1 CARD domain |
Function
for BCL10 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: BCL10_HUMAN, O95999Function: Promotes apoptosis, pro-caspase-9 maturation and activation of NF-kappa-B via NIK and IKK. May be an adapterprotein between upstream TNFR1-TRADD-RIP complex and the downstream NIK-IKK-IKAP complex. Is a substrate for MALT1 Genatlas biochemistry entry for BCL10:CARD containing apoptotic signaling protein,B cell CLL/lymphoma 10,cellular homolog of equine herpesvirus-2 E10gene,inducing NFKB activation
Clone
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OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for BCL10
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
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In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for BCL10 |
Gene Ontology (GO): 5/14 molecular function terms (GO ID links to tree view) (see all 14): About this table
BCL10 for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for BCL10:
Animal Models:
Mouse knock-outs for BCL10: Bcl10tm1Mak Bcl10tm1Swm
6 MGI mutant phenotypes (inferred from 2 alleles ) (MGI details for Bcl10):
BCL10 for phenotypes About GeneDecksing
|
Pathways & Interactions
for BCL10 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways - 5/18 super-pathways (see all 18) About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | B cell receptor signaling pathway | | | 2 | Immune System | | | 3 | TCR signaling | | | 4 | Signaling by the B Cell Receptor (BCR) | | | 5 | Immune response T cell receptor signaling pathway | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1 EMD Millipore Pathway for BCL10
5/6 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for BCL10 (see all 6)
3 
Cell Signaling Technology (CST) Pathways for BCL10
1  GeneGo (Thomson Reuters) Pathway for BCL10
5/6  BioSystems Pathways for BCL10 (see all 6)
5/9 
Reactome Pathways for BCL10 (see all 9)
3 
Kegg Pathways (Kegg details for BCL10):
BCL10 for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for BCL10
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/65 Interacting proteins for BCL10 (O959991, 2, 3 ENSP000002710154) via UniProtKB, MINT, STRING, and/or I2D (see all 65)About this table
Gene Ontology (GO): 5/29 biological process terms (GO ID links to tree view) (see all 29): About this table
BCL10 for ontologies About GeneDecksing
|
Drugs & Compounds
for BCL10 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
BCL10 for compounds About GeneDecksing
 Browse Tocris compounds for BCL10
5 Novoseek chemical compound relationships for BCL10 gene About this table
Search CenterWatch for drugs/clinical trials and news about BCL10
|
Transcripts
for BCL10 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for BCL10 gene: NM_003921.4 Unigene Cluster for BCL10: B-cell CLL/lymphoma 10 Hs.193516 [show with all ESTs]Unigene Representative Sequence: NM_0039212 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000370580(uc021opd.1) ENST00000271015
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for BCL10 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for BCL10
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: BCL10 (NM_003921) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for BCL10 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat BCL10 |
Additional cDNA sequence: AF057700.1 AF100338.1 AF105066.1 AF127386.1 AF134395.1 AK098790.1 AK291346.1 BC053617.1 BX647306.1 EF189176.1 9 DOTS entries: DT.454130 DT.95372482 DT.70103796 DT.99987237 DT.87005628 DT.121403880 DT.423492 DT.91997479 DT.95139454 24/83 AceView cDNA sequences (see all 83): BM988482 CA426727 BC053617 AF105066 NM_003921 AI990571 AA279060 AI221210 AW183179 AF127386 AF134395 BG393233 BU169446 AI952930 CA420027 BU621795 AI689618 AF082283 BU159849 AA179518 BX956474 AW961676 BU676530 AI753953
GeneLoc Exon Structure
|
Expression
for BCL10 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| BCL10 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --
About this image
See BCL10 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for BCL10
SOURCE GeneReport for Unigene cluster: Hs.193516
UniProtKB/Swiss-Prot: BCL10_HUMAN, O95999Tissue specificity: Ubiquitous
SABiosciences Expression via Pathway-Focused PCR Arrays including BCL10:
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for BCL10
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat BCL10 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat BCL10 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat BCL10 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for BCL10 |
Orthologs
for BCL10 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for BCL10 gene from 4/10 species (see all 10) About this table
ENSEMBL Gene Tree for BCL10 (if available)
TreeFam Gene Tree for BCL10 (if available) |
Paralogs
for BCL10 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for BCL10 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 1 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for BCL10 (85731459 - 85743771 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for BCL10
1 CNV: 47846
Human Gene Mutation Database (HGMD): BCL10
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing BCL10 |
|
Disorders
/ Diseases
for BCL10 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
BCL10 for disorders About GeneDecksing
OMIM gene information: 603517
OMIM disorders: --
UniProtKB/Swiss-Prot: BCL10_HUMAN, O95999
Note=A chromosomal aberration involving BCL10 is recurrent in low-grade mucosa-associated lymphoid tissue(MALT lymphoma). Translocation t(1;14)(p22;q32). Although the BCL10/IgH translocation leaves the coding region ofBCL10 intact, frequent BCL10 mutations could be attributed to the Ig somatic hypermutation mechanism resulting innucleotide transitions Note=Defects in BCL10 are involved in various types of cancer Defects in BCL10 are a cause of mesothelioma malignant (MESOM) [MIM:156240]. An aggressive neoplasm of theserosal lining of the chest. It appears as broad sheets of cells, with some regions containing spindle-shaped,sarcoma-like cells and other regions showing adenomatous patterns. Pleural mesotheliomas have been linked to exposureto asbestos
20/49  diseases for BCL10 (see all 49): About MalaCardsmalt lymphoma b-cell lymphomas marginal zone b-cell lymphoma b-cell non-hodgkin lymphoma
diffuse large b-cell lymphoma non-hodgkin lymphoma central nervous system lymphoma leukemia
pancreatic acinar cell adenocarcinoma testicular germ cell tumor germ cell tumor malignant mesothelioma
squamous cell carcinoma acinar cell carcinoma hodgkin's lymphoma plasma cell leukemia
laryngeal squamous cell carcinoma oral squamous cell carcinoma mantle cell lymphoma edwards syndrome
3 diseases from the University of Copenhagen DISEASES database for BCL10:Lymphoma Edwards syndrome Gallbladder lymphoma 10/29 Novoseek disease relationships for BCL10 gene (see all 29) About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| malt lymphoma |
92.6 |
158 |
15682443 (8), 11445840 (7), 16545185 (6), 15634591 (5) (see all 57) |
| lymphoma b-cell |
74.1 |
17 |
16784987 (2), 17167822 (2), 16440771 (1), 18346354 (1) (see all 13) |
| lymphoma |
70.7 |
60 |
16310461 (6), 11748643 (5), 10582682 (4), 18346354 (3) (see all 31) |
| lymphoma small lymphocytic |
59.3 |
1 |
16310461 (1) |
| pseudolymphoma |
50.5 |
1 |
18346354 (1) |
| somatic mutations |
50.2 |
13 |
11425462 (3), 11836626 (2), 11605060 (2), 10665648 (2) (see all 7) |
| lymphocytic leukemia chronic b-cell |
46.8 |
5 |
17540779 (1), 18252714 (1), 18550498 (1) |
| lymphoma follicular |
44.9 |
2 |
16310461 (2) |
| trisomy |
43.7 |
1 |
19961773 (1) |
| gastric lymphoma |
38.3 |
5 |
11425462 (3) |
Genatlas disease: BCL10 B cell/lymphoma 10,of mucosa associated lymphoid tissues (MALT lymphomas),affecting predominantly the gastricmucosa,low grade evolving to high grade form with translocation t(1;14)(p22;q32)
Genetic Association Database (GAD): BCL10
Human Genome Epidemiology (HuGE) Navigator: BCL10 (6 documents)
Export disorders for BCL10 gene to outside databases
|
Publications
for BCL10 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for BCL10 gene, integrated from 9 sources (see all 216):
(articles sorted by number of sources associating them with BCL10) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Bcl10 is involved in t(1;14)(p22;q32) of MALT B cell lymphoma and mutated in multiple tumor types. (PubMed id 9989495)1, 2, 3, 9 Willis T.G.... Dyer M.J.S. (1999)
- Interchangeable binding of Bcl10 to TRAF2 and cIAPs regulates apoptosis signaling. (PubMed id 11466612)1, 2, 9 Yui D.... Tohyama M. (2001)
- c-E10 is a caspase-recruiting domain-containing protein that interacts with components of death receptors signaling pathway and activates nuclear factor-kappaB. (PubMed id 10400625)1, 2, 9 Costanzo A.... Vito P. (1999)
- Negative feedback loop in T cell activation through IkappaB kinase-induced phosphorylation and degradation of Bcl10. (PubMed id 17213322)1, 2, 9 Lobry C....Weil R. (2007)
- Inactivating mutations and overexpression of BCL10, a caspase recruitment domain-containing gene, in MALT lymphoma with t(1;14)(p22;q32). (PubMed id 10319863)1, 2, 9 Zhang Q.... Morris S.W. (1999)
- Association of BCL10 germ line polymorphisms on chromosome 1p with advanced stage testicular germ cell tumor patients. (PubMed id 16229939)1, 4, 9 Inoue T....Habuchi T. (2006)
- Caveolin-1 triggers T-cell activation via CD26 in association with CARMA1. (PubMed id 17287217)1, 2, 9 Ohnuma K....Morimoto C. (2007)
- Absence of BCL10 mutations in human malignant mesothelioma. (PubMed id 10380921)1, 2, 9 Apostolou S.... Testa J.R. (1999)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- CLAP, a novel caspase recruitment domain-containing protein in the tumor necrosis factor receptor pathway, regulates NF-kappaB activation and apoptosis. (PubMed id 10364242)1, 2 Srinivasula S.M.... Alnemri E.S. (1999)
|
External Searches for BCL10 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing BCL10 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing BCL10 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing BCL10 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
|
About This Section
| Patent Information for BCL10 gene:
Search GeneIP for patents involving BCL10
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for BCL10 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
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| | |  | OriGene Antibodies for BCL10 | | OriGene shRNA RFP for BCL10 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for BCL10 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for BCL10 | | | OriGene Protein Over-expression Lysate for BCL10 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for BCL10 | | OriGene 3'-UTR Clone for BCL10 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for BCL10 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for BCL10 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for BCL10 | | OriGene Custom Protein Services for BCL10 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat BCL10 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing BCL10 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat BCL10 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat BCL10 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat BCL10 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat BCL10 |
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| | Antibodies & Assays for BCL10 (Bcl-10) |
| | | | Search Tocris compounds for BCL10 |
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 | | | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for BCL10 |
|  |  |  | | | | ThermoFisher Antibody for BCL10 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat BCL10 |
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