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BCHE Gene

protein-coding   GIFtS: 69

GC03M166973
butyrylcholinesterase
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
(Previous symbol: CHE1)
Services    

Aliases &
Descriptions
for BCHE

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc , and/or 7Ensembl, 8miRBase)
About This Section
Aliases
CHE1 2, 3, 5
E1 1, 2
EC 3.1.1.8 3
Pseudocholinesterase 3
butyrylcholinesterase 2
Descriptions
Acylcholine acylhydrolase 3
Butyrylcholine esterase 3
Choline esterase II 3
External Ids
HGNC: 9831
Entrez Gene: 5902
UniProtKB: P062763
Ensembl: ENSG000001142007
Search outside databases for aliases for BCHE gene

Previous GC identifers: GC03M162635 GC03M166531 GC03M166892 GC03M166811

Summaries
for BCHE

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

 EntrezGene summary for BCHE:
Mutant alleles at the BCHE locus are responsible for suxamethonium sensitivity. Homozygous persons
sustain prolonged apnea after administration of the muscle relaxant suxamethonium in connection
with surgical anesthesia. The activity of pseudocholinesterase in the serum is low and its
substrate behavior is atypical. In the absence of the relaxant, the homozygote is at no known
disadvantage. [provided by RefSeq]

Gene Wiki entry for BCHE (Butyrylcholinesterase)

Genomic Location
for BCHE

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

 Genomic View:
UCSC Golden Path with GeneCards custom track

 Transcription factor binding sites upstream to the BCHE gene  

Entrez Gene cytogenetic band: 3q26.1-q26.2   Ensembl cytogenetic band:  3q26.1   HGNC cytogenetic band: 3q26.1-q26.2

BCHE Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 3         GeneLoc Exon Structure

GeneLoc location for GC03M166973:     (about GC identifiers)

Start:
 166,973,386 bp from pter
End:
 167,037,947 bp from pter
Size:
 64,562 bases
Orientation:
 minus strand
RefSeq DNA sequence:
NC_000003.10  NT_005612.15  

Proteins
for BCHE

(According to 1UniProtKB, and/or Ensembl, Phosphorylation sites according to 2Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
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 UniProtKB/Swiss-Prot: CHLE_HUMAN, P06276 (See protein sequence)
Recommended Name: Cholinesterase precursor  
Size: 602 amino acids; 68418 Da
Subunit: Homotetramer. The tetramer is composed of two dimers. The two subunits in a dimer are
linked by a disulfide bond
Miscellaneous: Cholinesterase is highly reactive with organophosphate esters
PDB structures from and Proteopedia :
1EHO (3D)    1EHQ (3D)    1KCJ (3D)    1P0I (3D)    1P0M (3D)    1P0P (3D)    1P0Q (3D)    1XLU (3D)    
1XLV (3D)    1XLW (3D)    2J4C (3D)    2PM8 (3D)    3DJY (3D)    3DKK (3D)    
Secondary accessions: A8K7P8

REFSEQ proteins: NP_000046.1  

ENSEMBL proteins: 
ENSP00000264381 


Human Recombinant Proteins 
Browse Drug Discovery Central at Invitrogen for human recombinant proteins
Browse Purified and Recombinant Proteins at Millipore
Browse Human Recombinant Proteins at Sigma-Aldrich  
Browse R&D Systems for human recombinant proteins
Browse recombinant and purified proteins available from Enzo Life Sciences
Recombinant Proteins from Abcam (Butyrylcholinesterase)
Human Recombinant Proteins from Abnova (BCHE)
                Browse Origene for full length recombinant human proteins expressed in human HEK293 cells 

4 Gene Ontology (GO) cellular component terms (links to tree view):

GO IDQualified GO termEvidencePubMed IDs
GO:0005576 extracellular region NAS14718574
GO:0005641 nuclear envelope lumen IEA--
GO:0005783 endoplasmic reticulum IEA--
GO:0016020 membrane IEA--
About this table

Antibodies for BCHE: 
Browse Antibodies Central at Invitrogen
Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
Sigma-Aldrich Antibodies for BCHE
Browse R&D Systems for Antibodies
Antibodies from Abcam (Butyrylcholinesterase), each with their AbpromiseSM
Monoclonal and Polyclonal Antibodies from Abnova (BCHE)
Novus Biologicals Antibody for BCHE

Assays for BCHE: 
Browse Invitrogen for biochemical assays
Browse Kits and Assays available from Millipore
Browse R&D Systems for biochemical assays
Browse biochemical assays available from Enzo Life Sciences

Protein Domains/
Families
for BCHE

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section
5 InterPro domains/families:
 IPR019826 Carboxylesterase_B_AS
 IPR000997 Cholinesterase
 IPR014788 AChE_tetra
 IPR019819 Carboxylesterase_B_CS
 IPR002018 CarbesteraseB


   GeneDecks  BCHE for the domains selected above  
About GeneDecksing

Graphical View of Domain Structure for InterPro Entry P06276

ProtoNet protein and cluster: P06276

1 Blocks protein family: IPB000997 Cholinesterase signature

UniProtKB/Swiss-Prot: CHLE_HUMAN, P06276
Similarity: Belongs to the type-B carboxylesterase/lipase family

Gene Function
for BCHE

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section
Inhib.
RNA:		Invitrogen RNAi Products for gene knock-down (BCHE)
Browse for Gene Knock-down Tools from Millipore
Abnova Chimera RNAi Products for Gene knock-down (BCHE)
              OriGene 29mer shRNA kit in GFP-retroviral vector: NM_000055

              Applied Biosystems Silencer® siRNAs for BCHE

              Sigma-Aldrich siRNA and siRNA Panels for BCHE  
                     Sigma-Aldrich shRNA for BCHE  
                     Explore Sigma-Aldrich super-pooled esiRNAs  

Clones:Browse Clone Ranger at Invitrogen for clones
Browse Clones for the Expression of Recombinant Proteins Available from Millipore
              OriGene GFP tagged cDNA clone in CMV expression vector: NM_000055
                                 Myc/DDK tagged cDNA clone in CMV expression vector: NM_000055
                                 untagged cDNA clone in CMV expression vector: NM_000055 

Primers: Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers
              OriGene genome-wide validated SYBR primer pairs: NM_000055

UniProtKB/Swiss-Prot: CHLE_HUMAN, P06276
Catalytic activity: An acylcholine + H(2)O = choline + a carboxylate
Enzyme Number (IUBMB): EC 3.1.1.8 

Genatlas biochemistry entry for BCHE:
butyryl cholinesterase,serum,with contradictory evidence for association of the K variant with
Alzheimer disease,ApoE4 carrier

1 MGI mutant phenotype (inferred from 1 allele) (MGI details for Bche):

normal

4 Gene Ontology (GO) molecular function terms (links to tree view):

GO IDQualified GO termEvidencePubMed IDs
GO:0001540 beta-amyloid binding NAS11569538
GO:0004104 cholinesterase activity NAS--
GO:0016787 hydrolase activity IEA--
GO:0019899 enzyme binding NAS11569538
About this table

Pathways & Interactions
for BCHE

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to 1UniProtKB, 2MINT, and/or 3STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section


 Gene Network CentralTM Interacting Genes and Proteins Network for  BCHE 


5/16 Interacting proteins for BCHE (ENSP000002643813) via UniProtKB, MINT, and/or STRING (see all 16 )
InteractantInteraction Details
GeneCardExternal ID(s)
COLQENSP000003732983STRING (score=.975)
CHATENSP000003371033STRING (score=.915)
AATFENSP000002254023STRING (score=.869)
GPTENSP000003468213STRING (score=.806)
CFDENSP000003321393STRING (score=.75)
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1 Gene Ontology (GO) biological process term (links to tree view):

GO IDQualified GO termEvidencePubMed IDs
GO:0050783 cocaine metabolic process TAS8622553
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Drugs & Compounds
for BCHE

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Enzo Life Sciences drugs & compounds for BCHE
Sigma-Aldrich Small Molecules for BCHE:
Inhibitor

Compounds for BCHE available from Tocris Bioscience
CompoundAction CAS number
Tacrine hydrochlorideCholinesterase inhibitor[1684-40-8]
Physostigmine hemisulfateCholinesterase inhibitor[64-47-1]
Galanthamine hydrobromideCholinesterase inhibitor[1953-04-4]
Ambenonium dichlorideCholinesterase inhibitor[52022-31-8]
AcephateAnticholinesterase insecticide[30560-19-1]
About this table


10/49 Novoseek chemical compound relationships for BCHE gene (see all 49 )
Compound   Score   Articles   PubMed IDs for Articles with Shared Sentences (# sentences)
butyrylthiocholine 95.59 40 8449554 (3), 10340441 (2), 8367669 (2), 1373381 (1) (see all 29)
butyrylcholine 91.92 20 9191541 (2), 12501914 (2), 14711311 (1), 7695328 (1) (see all 14)
benzoylcholine 91.74 9 14686935 (2), 15128307 (1), 10919342 (1), 16434764 (1) (see all 5)
o-nitrophenyl butyrate 89.58 2 1390935 (1), 8314794 (1)
acylcholine 88.62 7 2268667 (1), 2009086 (1), 1380483 (1), 1599981 (1) (see all 5)
o-nitroacetanilide 87.68 4 16824479 (1), 18208347 (1)
acetylthiocholine 87.11 25 8449554 (4), 10340441 (2), 8367669 (2), 15137175 (1) (see all 12)
succinyldithiocholine 86.74 2 9047329 (1), 12603134 (1)
bw 284 c 51 86.50 10 10340441 (1), 11801199 (1), 17300836 (1), 9398183 (1) (see all 9)
choline ester 85.45 5 2332047 (1), 10421452 (1), 17636231 (1)
About this table

4 PharmGKB drug compound relationships for BCHE gene
Drug compound PharmGKB Relations PubMed IDs for articles supporting these relationships
dibucaineFA  GN  12724618
irinotecanFA  10197614
rivastigmineCO  PD  GN  12668920
succinylcholineCO  2195556
About this table


Transcripts
for BCHE

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section
Inhib.
RNA:		Invitrogen RNAi Products for gene knock-down (BCHE)
Browse for Gene Knock-down Tools from Millipore
Abnova Chimera RNAi Products for Gene knock-down (BCHE)
              OriGene 29mer shRNA kit in GFP-retroviral vector: NM_000055

              Sigma-Aldrich siRNA and siRNA Panels for BCHE  
                     Sigma-Aldrich shRNA for BCHE  
                     Explore Sigma-Aldrich super-pooled esiRNAs  

Applied Biosystems Silencer® siRNAs: 

NM_000055  

REFSEQ mRNAs for BCHE gene: 

NM_000055.2   

Applied Biosystems TaqMan ® Gene Expression Assays: 

NM_000055  

              OriGene GFP tagged cDNA clone in CMV expression vector: NM_000055
                                 Myc/DDK tagged cDNA clone in CMV expression vector: NM_000055
                                 untagged cDNA clone in CMV expression vector: NM_000055 

Additional cDNA sequence: 

AK292063.1 BC008396.1 BC018141.1 CR611139.1 CR612468.1 M16474.1 M16541.1 

22 DOTS entries:

DT.313157  DT.95166895  DT.92461332  DT.95166782  DT.95166702  DT.92461340  DT.95166968  DT.95166838 
DT.95166925  DT.95166971  DT.100825393  DT.92461339  DT.92461344  DT.92461348  DT.92461349  DT.95166725 
DT.95166766  DT.95166916  DT.95166922  DT.95253862  DT.92023343  DT.92461343 

24/276 AceView cDNA sequences (see all 276 ):

CR612468 BP375392 AU117425 AL515531 BF514908 BQ636338 BU194860 BC018141 
CR611139 CB153819 BG460986 CB161794 BG461123 T28216 BG548545 BP378539 
BG460188 BG460576 BP376574 BM090671 BC008396 BX348709 BG459911 AA992576 

highest scoring ESTs for BCHE:

M16541 AA090958 AL515531 AL602693 AL706210 BC008396 BC018141 BE890381 BE893471 BF541023 

Unigene Cluster for BCHE:

Butyrylcholinesterase
Hs.420483  [show with all ESTs]
Unigene Representative Sequence: CD014090


GeneLoc Exon Structure

4 Alternative Splicing Database (ASD) splice patterns (SP) for BCHE

ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4 ^ 5 ^ 6a · 6b
SP1:                          -                           
SP2:                                      -               
SP3:                          -           -               
SP4:                    -     -           -               

About this scheme

ECgene alternative splicing isoforms for BCHE

1 Ensembl transcript including schematic representation:
ENST00000264381  

Expression
for BCHE

(Experimental results according to 1GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to 2GeneAnnot , 3GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

BCHE expression in normal and diseased human tissues

 Applied Biosystems TaqMan ® Gene Expression Assays for BCHE

1 / 2 / 3

3 probe-sets matching BCHE gene


Affymetrix
probe-set		 Array  GeneAnnot data GeneNote data GeneTide data
# genes Sensitivity Specificity Correlation Length Gb_Accession Consensus Uniqueness Score Rank
37841_at2, 3 U95-A 1 1.00 1.00 1.00 1.00 M16541 1.00 1.00 1.00 1

205433_at2, 3 U133-A 1 1.00 1.00 -- -- NM_000055 0.60 1.00 0.82 1

205433_at2 U133Plus2 1 1.00 1.00 -- -- -- -- -- -- --
GeneDecks  BCHE for binary patterns associated with the probe-sets selected above  
About GeneDecksing
About this table    
Data from (Publications) and GNF BioGPS
    About these images
About these images

CGAP SAGE TAG: ATGGACTGGA

SOURCE GeneReport for Unigene cluster: Hs.420483

Expression variation in blood from EXPOLDB for BCHE

UniProtKB/Swiss-Prot: CHLE_HUMAN, P06276
Tissue specificity: Present in most cells except erythrocytes

Orthologs
for BCHE

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD and/or 5MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section
Orthologs for BCHE gene from 5/10 species (see all 10 )
Organism Gene Locus Description Human
Similarity		 NCBI accessions
dog
(Canis familiaris)		 BCHE1   -- butyrylcholinesterase 89.26(n)
86.71(a)		 488143  XM_545267.2  XP_545267.2 
chimpanzee
(Pan troglodytes)		 BCHE1   -- butyrylcholinesterase 99.5(n)
99.17(a)		 460830  XM_516857.2  XP_516857.2 
cow
(Bos taurus)		 BCHE1   -- butyrylcholinesterase 90.14(n)
89.7(a)		 534616  NM_001076906.1  NP_001070374.1 
rat
(Rattus norvegicus)		 Bche1   -- butyrylcholinesterase 81.51(n)
79.93(a)		 65036  NM_022942.1  NP_075231.1 
mouse
(Mus musculus)		 Bche1, 5 35
 butyrylcholinesterase1, 5 80.86(n)1
80.3(a)1		 120381  NM_009738.31  NP_033868.31 
 AK0503375  AK0522005  (see all 10)
About this table        Species with no ortholog for BCHE

ENSEMBL Gene Tree for BCHE

Paralogs
for BCHE

(Paralogs according to 1HomoloGene
and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
About This Section

Paralogs for BCHE gene
TG2  ACHE2  

SNPs/Variants
for BCHE

(According to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section


10/410 NCBI SNPs in BCHE are shown (see all 410 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay)  (see all 163)
ABGenomic DataTranscription DataAllele Frequencies
SNP IDValidChr 3 posSequenceRecsAA
Chg		TypeMoreRecsAllele
freq		PopTotal
sample		More
------------
rs26682021,2
A,C,F,H,O166973162(+) AGGTAA/GTTCAC 1 -- ng519Minor allele frequency- G:0.49EU EA WA NA 734
rs13980881,2
A,C,F,H,O167038682(+) TTGATG/AAACTC 1 -- ng3110Minor allele frequency- A:0.07EA NA EU WA 2006
rs98384431,2
A,C,F,H167039261(+) ATACAT/CAATCT 1 -- ng314Minor allele frequency- C:0.45EU EA WA 406
rs38066501,2
A,C,F,H167038505(-) TGTGGT/CTTCTC 1 -- ng3112Minor allele frequency- C:0.27EA NA EU WA 2470
rs17998071,2
C,F,H,O167031223(-) CATAGA/GTCAAA 1 D/G mis1 ese312Minor allele frequency- G:0.00NA EU EA WA 1056
rs11266801,2
C,F,H167037819(-) ACTTTG/ACCATC 1 -- ut519Minor allele frequency- A:0.02NS EU EA WA 520
rs67718171,2
C,F,H167039794(+) GCATAC/AGGTCA 1 -- ng3116Minor allele frequency- A:0.07NS NA EU EA WA 1084
rs168497001,2
C,F,H167030667(+) TCATTC/GTCTCT 1 E/D mis112Minor allele frequency- G:0.02NA EU EA WA 1052
rs26864041,2
C,F,H166973126(+) ATGCAT/CCCACT 1 -- ng514Minor allele frequency- C:0.11EU EA WA 418
rs34951,2
A,C,F166973675(-) AGAACA/GTGTTT 1 -- ut315Minor allele frequency- G:0.46MN NA 512
About this table

HapMap Linkage Disequilibrium images for BCHE (up to first 250kb)

Disorders & Mutations
for BCHE

(in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

 OMIM: 177400

UniProtKB/Swiss-Prot: CHLE_HUMAN, P06276

  • Defects in BCHE are the cause of butyrylcholinesterase deficiency (BChE deficiency)
    [MIM:177400]. BChE deficiency is a metabolic disorder characterized by prolonged apnoea after the
    use of certain anesthetic drugs, including the muscle relaxants succinylcholine or mivacurium and
    other ester local anesthetics. The duration of the prolonged apnoea varies significantly depending
    on the extent of the enzyme deficiency. BChE deficiency is a multifactorial disorder. The
    hereditary condition is transmitted as an autosomal recessive trait

    • 10/68 Novoseek disease relationships for BCHE gene (see all 68 )

    Disease   Score   Articles   PubMed IDs for Articles with Shared Sentences (# sentences)
    pseudocholinesterase deficiency 92.68 24 17805000 (4), 17613911 (3), 15905758 (2), 10614702 (2) (see all 15)
    alzheimers disease 76.19 138 17681768 (4), 15510242 (3), 17553629 (3), 16275899 (2) (see all 84)
    poisoning 64.66 30 18937214 (3), 19428953 (3), 2379248 (2), 15462154 (1) (see all 16)
    cocaine intoxication 57.36 4 9266811 (1), 9673783 (1), 9266810 (1), 9882701 (1)
    spina bifida open 54.62 3 7647148 (2), 1705434 (1)
    senile plaques 54.53 16 9165483 (2), 9403484 (2), 10893490 (1), 7979218 (1) (see all 12)
    dementia 52.34 41 12668920 (3), 1469405 (2), 7979218 (2), 12796550 (2) (see all 24)
    intoxication 48.46 6 18076380 (1), 10437130 (1), 14600276 (1), 10794391 (1) (see all 6)
    neurofibrillary tangles 46.43 8 8004445 (2), 10893490 (1), 8792327 (1), 8239315 (1) (see all 5)
    dementia vascular 38.56 3 12417373 (1), 15219807 (1), 15633941 (1)
    About this table

    1 PharmGKB disease relationship for BCHE gene
    Disease PharmGKB Relations PubMed IDs for articles supporting these relationships
    DementiaCO  PD  GN  12668920
    About this table

    Genatlas disease: BCHE
    apnea,postanesthetic,suxamethonium sensitivity,hypocholinesterasemia or acholinesterasemia

    Human Gene Mutation Database: BCHE
    Genetic Association Database: BCHE
    Human Genome Epidemiology Navigator: BCHE (49 documents)

    Medical News
    for BCHE

    (Possibly Related Articles in Doctor's Guide)
    About This Section

    Publications
    for BCHE

    (in PubMed. Associations of this gene to articles via 1Novoseek, 2HGNC, 3Entrez Gene, 4UniProtKB/Swiss-Prot, 5UniProtKB/TrEMBL, 6GAD, and/or 7PharmGKB)
    About This Section

    		10/550 PubMed articles for BCHE gene (see all 550 ):

    Search for BCHE

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

     ANDOR
    Aliases
    Free Text  
      Query String
    		PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    Genome Databases showing BCHE

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
    About This Section
    Entrez Gene: 590 HGNC: 983 AceView: BCHE Ensembl:ENSG00000114200 euGenes: HUgn590
    ECgene: BCHE H-InvDB: BCHE

    Other Databases showing BCHE

    (According to HUGE)
    About This Section

    		   --

    Specialized Databases showing BCHE

    (According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    ATLAS Chromosomes in Cancer entry for BCHE Genetics and Cytogenetics in Oncology and Haematology

    Licensable Technologies
    for BCHE

    (Available from WIS Yeda, Salk, Tufts)
    About This Section

    		  --

    Services
    for BCHE

    (Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
    Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
    Enzo Life Sciences, and/or Tocris Bioscience)
    About This Section



    Products for BCHE:
     TaqMan ® Gene Expression Assays
     TaqMan ® Genotyping Assays
    		  Free SNP selection tool



      Invitrogen iPath Pathways  Invitrogen BLOCK-iT™ RNAi
      Invitrogen Antibodies  Invitrogen Assays
      Invitrogen Clones  Invitrogen Q-PCR Products
      Invitrogen Human Recombinant Kinases  Invitrogen Custom Antibody and Peptide Service
      Invitrogen Proteins / Assays / Screening Services  Search Invitrogen catalog for BCHE-related products

     Millipore Custom Antibody & Bulk Services
     Millipore Preclinical / Clinical Development Services
     Millipore Immunoassay Services
     Millipore Target Screening & Profiling Services


     Predesigned and custom siRNAs for BCHE Antibodies for BCHE
     Explore super-pooled esiRNAs Browse proteins at Sigma-Aldrich
     Lentivirus-delivered shRNAs for BCHE Small molecules for BCHE
     "Your Favorite Gene" Pathwaysfeedback


      
     Antibodies   Primer Pairs  
     Cell Culture Products   ELISAs  
     Flow Cytometry Kits   Protease Activity Assays & Reagents  
     Cell Selection/Detection Kits & Reagents   ELISA/Assay Development Kits & Reagents  
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