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Aliases for BCHE Gene

Aliases for BCHE Gene

  • Butyrylcholinesterase 2 3 5
  • Acylcholine Acylhydrolase 3 4
  • Cholinesterase (Serum) 2 2 3
  • Butyrylcholine Esterase 3 4
  • Pseudocholinesterase 3 4
  • Choline Esterase II 3 4
  • Cholinesterase 1 2 3
  • EC 3.1.1.8 4 61
  • CHE1 3 4
  • Cholinesterase 3
  • EC 3.1.1 61
  • CHE2 3
  • E1 3

External Ids for BCHE Gene

Previous HGNC Symbols for BCHE Gene

  • CHE1
  • CHE2

Previous GeneCards Identifiers for BCHE Gene

  • GC03M162635
  • GC03M166531
  • GC03M166892
  • GC03M166811
  • GC03M166973
  • GC03M165490
  • GC03M162859

Summaries for BCHE Gene

Entrez Gene Summary for BCHE Gene

  • This gene encodes a cholinesterase enzyme and member of the type-B carboxylesterase/lipase family of proteins. The encoded enzyme exhibits broad substrate specificity and is involved in the detoxification of poisons including organophosphate nerve agents and pesticides, and the metabolism of drugs including cocaine, heroin and aspirin. Humans homozygous for certain mutations in this gene exhibit prolonged apnea after administration of the muscle relaxant succinylcholine. [provided by RefSeq, Jul 2016]

GeneCards Summary for BCHE Gene

BCHE (Butyrylcholinesterase) is a Protein Coding gene. Diseases associated with BCHE include Pseudocholinesterase Deficiency and Curariform Drugs Toxicity. Among its related pathways are Neurotransmitter Clearance In The Synaptic Cleft and Glycerophospholipid biosynthesis. GO annotations related to this gene include identical protein binding and hydrolase activity. An important paralog of this gene is ACHE.

UniProtKB/Swiss-Prot for BCHE Gene

  • Esterase with broad substrate specificity. Contributes to the inactivation of the neurotransmitter acetylcholine. Can degrade neurotoxic organophosphate esters.

Tocris Summary for BCHE Gene

  • Cholinesterases inactivate the neurotransmitter acetylcholine by catalyzing its hydrolysis to choline and acetic acid. Acetylcholinesterase (AChE) is found in erythroid cells and at neuronal synapses, whilst butyrylcholinesterase is mostly expressed in the liver.

Gene Wiki entry for BCHE Gene

No data available for PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for BCHE Gene

Genomics for BCHE Gene

Regulatory Elements for BCHE Gene

Enhancers for BCHE Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
- Elite enhancer/Elite enhancer-gene association

Enhancers around BCHE on UCSC Golden Path with GeneCards custom track

Promoters for BCHE Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around BCHE on UCSC Golden Path with GeneCards custom track

Genomic Location for BCHE Gene

Chromosome:
3
Start:
165,772,904 bp from pter
End:
165,837,472 bp from pter
Size:
64,569 bases
Orientation:
Minus strand

Genomic View for BCHE Gene

Genes around BCHE on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
BCHE Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for BCHE Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for BCHE Gene

Proteins for BCHE Gene

  • Protein details for BCHE Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P06276-CHLE_HUMAN
    Recommended name:
    Cholinesterase
    Protein Accession:
    P06276
    Secondary Accessions:
    • A8K7P8

    Protein attributes for BCHE Gene

    Size:
    602 amino acids
    Molecular mass:
    68418 Da
    Quaternary structure:
    • Homotetramer; disulfide-linked. Dimer of dimers.

    Three dimensional structures from OCA and Proteopedia for BCHE Gene

neXtProt entry for BCHE Gene

Post-translational modifications for BCHE Gene

  • N-glycosylated. No other PTM detected (PubMed:20946535). The major N-glycan structures are of the complex diantennary type with 1 and 2 N-acetylneuraminic acid molecules (Neu5Ac) making up approximately 33% and 47% of the total N-glycans, respectively. Only low amounts of fucosylated diantennary N-glycans are detected (approximately 2%). Triantennary N-glycans with or without fucose amount to approximately 13%, whereas 5% of the total N-glycans are of the oligomannosidic or hybrid type.
  • Glycosylation at Asn 45, Asn 85, Asn 134, Asn 269, Asn 284, Asn 369, Asn 483, Asn 509, Asn 513, and Asn 514
  • Modification sites at PhosphoSitePlus

Other Protein References for BCHE Gene

Antibody Products

  • R&D Systems Antibodies for BCHE (Butyrylcholinesterase/BCHE)

Domains & Families for BCHE Gene

Suggested Antigen Peptide Sequences for BCHE Gene

Graphical View of Domain Structure for InterPro Entry

P06276

UniProtKB/Swiss-Prot:

CHLE_HUMAN :
  • Belongs to the type-B carboxylesterase/lipase family.
Family:
  • Belongs to the type-B carboxylesterase/lipase family.
genes like me logo Genes that share domains with BCHE: view

No data available for Gene Families for BCHE Gene

Function for BCHE Gene

Molecular function for BCHE Gene

GENATLAS Biochemistry:
butyryl cholinesterase,serum,with contradictory evidence for association of the K variant with Alzheimer disease,ApoE4 carrier
UniProtKB/Swiss-Prot BiophysicochemicalProperties:
Kinetic parameters: KM=18.0 uM for butyrylthiocholine (at 25 degrees Celsius) {ECO:0000269 PubMed:25054547};
UniProtKB/Swiss-Prot CatalyticActivity:
An acylcholine + H(2)O = choline + a carboxylate.
UniProtKB/Swiss-Prot EnzymeRegulation:
Inhibited by mercury. Inhibited by Tabun. Tabun forms a covalent adduct with Ser-226 that becomes irreversible upon aging.
UniProtKB/Swiss-Prot Function:
Esterase with broad substrate specificity. Contributes to the inactivation of the neurotransmitter acetylcholine. Can degrade neurotoxic organophosphate esters.

Enzyme Numbers (IUBMB) for BCHE Gene

Gene Ontology (GO) - Molecular Function for BCHE Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0001540 beta-amyloid binding NAS 11569538
GO:0003824 catalytic activity NAS 11569538
GO:0003990 acetylcholinesterase activity IEA,ISS --
GO:0004104 cholinesterase activity IEA,IDA 19452557
GO:0016788 hydrolase activity, acting on ester bonds TAS --
genes like me logo Genes that share ontologies with BCHE: view
genes like me logo Genes that share phenotypes with BCHE: view

Human Phenotype Ontology for BCHE Gene

HPO Id HPO Name Alternative Ids Definition Synonyms

Animal Models for BCHE Gene

MGI Knock Outs for BCHE:

Animal Model Products

CRISPR Products

miRNA for BCHE Gene

miRTarBase miRNAs that target BCHE

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Transcription Factor Targets and HOMER Transcription for BCHE Gene

Localization for BCHE Gene

Subcellular locations from UniProtKB/Swiss-Prot for BCHE Gene

Secreted.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for BCHE Gene COMPARTMENTS Subcellular localization image for BCHE gene
Compartment Confidence
extracellular 5
endoplasmic reticulum 4
nucleus 3
cytoskeleton 2
cytosol 2
lysosome 2
mitochondrion 2
plasma membrane 2
vacuole 2
peroxisome 1

Gene Ontology (GO) - Cellular Components for BCHE Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005576 extracellular region TAS --
GO:0005615 extracellular space IEA --
GO:0005641 nuclear envelope lumen IEA --
GO:0005783 endoplasmic reticulum IEA --
GO:0005788 endoplasmic reticulum lumen IEA --
genes like me logo Genes that share ontologies with BCHE: view

Pathways & Interactions for BCHE Gene

genes like me logo Genes that share pathways with BCHE: view

Interacting Proteins for BCHE Gene

Gene Ontology (GO) - Biological Process for BCHE Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007584 response to nutrient IEA --
GO:0007612 learning IEA --
GO:0008285 negative regulation of cell proliferation IEA --
GO:0014016 neuroblast differentiation IEA --
GO:0019695 choline metabolic process IEA --
genes like me logo Genes that share ontologies with BCHE: view

No data available for SIGNOR curated interactions for BCHE Gene

Drugs & Compounds for BCHE Gene

(142) Drugs for BCHE Gene - From: DrugBank, PharmGKB, ApexBio, DGIdb, FDA Approved Drugs, HMDB, Tocris, and Novoseek

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Rivastigmine Approved, Investigational Pharma inhibitor, Target Cholinesterase inhibitor 82
Bambuterol Approved Pharma agonist, Enzyme, substrate, inhibitor 4
succinylcholine Approved Pharma Full agonist, Agonist, Enzyme, substrate 154
Demecarium Approved Pharma inhibitor, Target 0
Hexafluronium Approved Pharma inhibitor, Target 0

(81) Additional Compounds for BCHE Gene - From: HMDB, Novoseek, and Tocris

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
Arachidic acid
  • Arachate
  • Arachic acid
  • Arachidate
  • Arachidic acid
  • Eicosanoate
506-30-9
D-Mannose
  • (+)-mannose
  • (+-)-mannose
  • Carubinose
  • D(+)-Mannose
  • D-Mannopyranose
3458-28-4
Heptadecanoic acid
  • Heptadecanoate
  • Heptadecanoic acid
  • Margarate
  • Margaric acid
  • Margarinate
506-12-7
Heptadecanoyl CoA
  • Heptadecanoate
  • Heptadecanoic acid
  • Heptadecanoic acid coa
  • Heptadecanoyl coenzyme A
  • Heptadecanoyl-coA
3546-17-6
Pentadecanoic acid
  • N-Pentadecanoate
  • N-Pentadecanoic acid
  • N-Pentadecylate
  • N-Pentadecylic acid
  • Pentadecanoate
1002-84-2

(5) Tocris Compounds for BCHE Gene

Compound Action Cas Number
Ambenonium dichloride Cholinesterase inhibitor 115-79-7
Donepezil hydrochloride Potent AChE inhibitor 120011-70-3
Galanthamine hydrobromide Cholinesterase inhibitor 1953-04-4
Rivastigmine tartrate Dual AChE and BChE inhibitor 129101-54-8
Tacrine hydrochloride Cholinesterase inhibitor 1684-40-8

(11) ApexBio Compounds for BCHE Gene

Compound Action Cas Number
Acephate 30560-19-1
Ambenonium dichloride 115-79-7
GSK 264220A 685506-42-7
JW 642 1416133-89-5
KML 29 1380424-42-9
Neostigmine Bromide Cholinesterase inhibitor 114-80-7
PE 154 1192750-33-6
Phenserine 101246-66-6
Physostigmine hemisulfate 64-47-1
Pristimerin 1258-84-0
Tacrine hydrochloride 1684-40-8
genes like me logo Genes that share compounds with BCHE: view

Transcripts for BCHE Gene

Unigene Clusters for BCHE Gene

Butyrylcholinesterase:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for BCHE Gene

ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4 ^ 5 ^ 6a · 6b
SP1: -
SP2: -
SP3: - -
SP4: - - -

Relevant External Links for BCHE Gene

GeneLoc Exon Structure for
BCHE
ECgene alternative splicing isoforms for
BCHE

Expression for BCHE Gene

mRNA expression in normal human tissues for BCHE Gene

mRNA differential expression in normal tissues according to GTEx for BCHE Gene

This gene is overexpressed in Fallopian Tube (x5.7), Liver (x5.5), Esophagus - Muscularis (x4.4), and Esophagus - Gastroesophageal Junction (x4.0).

Protein differential expression in normal tissues from HIPED for BCHE Gene

This gene is overexpressed in Serum (34.6), Plasma (13.4), and Synovial fluid (8.3).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for BCHE Gene



NURSA nuclear receptor signaling pathways regulating expression of BCHE Gene:

BCHE

SOURCE GeneReport for Unigene cluster for BCHE Gene:

Hs.420483

mRNA Expression by UniProt/SwissProt for BCHE Gene:

P06276-CHLE_HUMAN
Tissue specificity: Detected in blood plasma (at protein level). Present in most cells except erythrocytes.
genes like me logo Genes that share expression patterns with BCHE: view

Primer Products

No data available for Protein tissue co-expression partners for BCHE Gene

Orthologs for BCHE Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for BCHE Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia BCHE 34
  • 90.14 (n)
  • 89.7 (a)
BCHE 35
  • 90 (a)
OneToOne
dog
(Canis familiaris)
Mammalia BCHE 34
  • 89.26 (n)
  • 86.71 (a)
BCHE 35
  • 87 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Bche 34
  • 80.91 (n)
  • 80.3 (a)
Bche 16
Bche 35
  • 79 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia BCHE 34
  • 99.5 (n)
  • 99.17 (a)
BCHE 35
  • 99 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Bche 34
  • 81.51 (n)
  • 79.93 (a)
oppossum
(Monodelphis domestica)
Mammalia BCHE 35
  • 75 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia BCHE 35
  • 78 (a)
OneToOne
chicken
(Gallus gallus)
Aves BCHE 34
  • 73.19 (n)
  • 72.01 (a)
BCHE 35
  • 71 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia BCHE 35
  • 67 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC100495889 34
  • 69.16 (n)
  • 65.72 (a)
fruit fly
(Drosophila melanogaster)
Insecta Ace 36
  • 37 (a)
alpha-Est10 36
  • 29 (a)
alpha-Est2 36
  • 28 (a)
alpha-Est3 36
  • 39 (a)
alpha-Est4 36
  • 28 (a)
alpha-Est5 36
  • 25 (a)
alpha-Est6 36
  • 27 (a)
alpha-Est7 36
  • 30 (a)
alpha-Est8 36
  • 36 (a)
alpha-Est9 36
  • 29 (a)
BcDNA:GH05741 36
  • 29 (a)
CG10175 36
  • 28 (a)
CG3841 36
  • 35 (a)
CG4382 36
  • 29 (a)
CG5397 36
  • 27 (a)
CG6018 36
  • 40 (a)
CG6414 36
  • 30 (a)
CG7529 36
  • 30 (a)
CG8424 36
  • 30 (a)
clt 36
  • 28 (a)
Est-6 36
  • 32 (a)
Est-P 36
  • 34 (a)
Gli 36
  • 30 (a)
Jhe 36
  • 29 (a)
Ace 35
  • 34 (a)
OneToMany
worm
(Caenorhabditis elegans)
Secernentea ace-1 36
  • 40 (a)
ace-2 36
  • 37 (a)
ace-3 36
  • 37 (a)
ace-4 36
  • 39 (a)
B0238.1 36
  • 30 (a)
B0238.13 36
  • 37 (a)
B0238.7 36
  • 30 (a)
C52A10.1 36
  • 31 (a)
C52A10.2 36
  • 30 (a)
F07C4.12 36
  • 29 (a)
F13H6.3 36
  • 32 (a)
F15A8.6 36
  • 28 (a)
F55D10.3 36
  • 29 (a)
ges-1 36
  • 29 (a)
K07C11.4 36
  • 29 (a)
K11G9.1 36
  • 31 (a)
K11G9.2 36
  • 30 (a)
K11G9.3 36
  • 30 (a)
R173.3 36
  • 42 (a)
T02B5.1 36
  • 23 (a)
T02B5.3 36
  • 26 (a)
T07H6.1a 36
  • 40 (a)
T28C12.4a 36
  • 29 (a)
T28C12.4b 36
  • 29 (a)
T28C12.5 36
  • 37 (a)
Y71H2AM.13 36
  • 28 (a)
Y75B8A.3 36
  • 36 (a)
ace-1 35
  • 40 (a)
ManyToMany
ace-2 35
  • 34 (a)
ManyToMany
ace-3 35
  • 34 (a)
ManyToMany
ace-4 35
  • 35 (a)
ManyToMany
bread mold
(Neurospora crassa)
Ascomycetes NCU06573 34
  • 41.93 (n)
  • 32.88 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 35
  • 32 (a)
OneToMany
Species where no ortholog for BCHE was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • zebrafish (Danio rerio)

Evolution for BCHE Gene

ENSEMBL:
Gene Tree for BCHE (if available)
TreeFam:
Gene Tree for BCHE (if available)

Paralogs for BCHE Gene

Paralogs for BCHE Gene

genes like me logo Genes that share paralogs with BCHE: view

Variants for BCHE Gene

Sequence variations from dbSNP and Humsavar for BCHE Gene

SNP ID Clin Chr 03 pos Sequence Context AA Info Type
rs1799807 Butyrylcholinesterase deficiency (BChE deficiency) 165,830,741(-) CATAG(A/G)TCAAA reference, missense
rs121918557 Butyrylcholinesterase deficiency (BChE deficiency) 165,829,962(-) CTTTT(A/T)TAGTC reference, missense
rs1803274 Butyrylcholinesterase deficiency (BChE deficiency) 165,773,492(-) ATGAA(A/G)CAGAA reference, missense
rs56309853 Butyrylcholinesterase deficiency (BChE deficiency) 165,830,879(+) TTACC(A/G/T)TGCCA reference, missense
rs531738678 Butyrylcholinesterase deficiency (BChE deficiency) 165,830,868(+) AAGAA(A/T)GGCTG reference, missense

Structural Variations from Database of Genomic Variants (DGV) for BCHE Gene

Variant ID Type Subtype PubMed ID
dgv4977n100 CNV loss 25217958
dgv8724n54 CNV loss 21841781
esv2657931 CNV deletion 23128226
esv3324020 CNV insertion 20981092
esv3342369 CNV insertion 20981092
esv3598510 CNV loss 21293372
esv3598511 CNV loss 21293372
esv3598513 CNV loss 21293372
esv3598515 CNV loss 21293372
esv3598516 CNV gain 21293372
esv3893808 CNV loss 25118596
nsv1004712 CNV gain 25217958
nsv428426 CNV loss 18775914
nsv520596 CNV gain+loss 19592680
nsv592472 CNV gain 21841781

Variation tolerance for BCHE Gene

Residual Variation Intolerance Score: 81.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 7.64; 82.79% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for BCHE Gene

Human Gene Mutation Database (HGMD)
BCHE
SNPedia medical, phenotypic, and genealogical associations of SNPs for
BCHE

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for BCHE Gene

Disorders for BCHE Gene

MalaCards: The human disease database

(15) MalaCards diseases for BCHE Gene - From: GeneTests, Orphanet, Swiss-Prot, DISEASES, Novoseek, and GeneCards

Disorder Aliases PubMed IDs
pseudocholinesterase deficiency
  • succinylcholine sensitivity
curariform drugs toxicity
cocaine intoxication
functional colonic disease
  • colonic diseases, functional
colonic pseudo-obstruction
  • primary chronic pseudo-obstruction of colon
- elite association - COSMIC cancer census association via MalaCards
Search BCHE in MalaCards View complete list of genes associated with diseases

UniProtKB/Swiss-Prot

CHLE_HUMAN
  • Butyrylcholinesterase deficiency (BChE deficiency) [MIM:177400]: A metabolic disorder characterized by prolonged apnea after the use of certain anesthetic drugs, including the muscle relaxants succinylcholine or mivacurium and other ester local anesthetics. The duration of the prolonged apnea varies significantly depending on the extent of the enzyme deficiency. {ECO:0000269 PubMed:10404729, ECO:0000269 PubMed:11928765, ECO:0000269 PubMed:12881446, ECO:0000269 PubMed:1306123, ECO:0000269 PubMed:1349196, ECO:0000269 PubMed:1415224, ECO:0000269 PubMed:15563885, ECO:0000269 PubMed:15781196, ECO:0000269 PubMed:1611188, ECO:0000269 PubMed:16788378, ECO:0000269 PubMed:17700357, ECO:0000269 PubMed:18075469, ECO:0000269 PubMed:18300943, ECO:0000269 PubMed:25054547, ECO:0000269 PubMed:25264279, ECO:0000269 PubMed:2915989, ECO:0000269 PubMed:7634491, ECO:0000269 PubMed:8554068, ECO:0000269 PubMed:8680411, ECO:0000269 PubMed:9110359, ECO:0000269 PubMed:9191541, ECO:0000269 PubMed:9388484, ECO:0000269 PubMed:9543549, ECO:0000269 PubMed:9694584}. Note=The disease is caused by mutations affecting the gene represented in this entry.

Genatlas disease for BCHE Gene

apnea,postanesthetic,suxamethonium sensitivity,hypocholinesterasemia or acholinesterasemia

Relevant External Links for BCHE

Genetic Association Database (GAD)
BCHE
Human Genome Epidemiology (HuGE) Navigator
BCHE
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
BCHE
genes like me logo Genes that share disorders with BCHE: view

Publications for BCHE Gene

  1. Naturally occurring mutation Leu307Pro of human butyrylcholinesterase in the Vysya community of India. (PMID: 16788378) Manoharan I. … Boopathy R. (Pharmacogenet. Genomics 2006) 3 4 22 46 65
  2. Butyrylcholinesterase (BCHE) genotyping for post-succinylcholine apnea in an Australian population. (PMID: 12881446) Yen T. … Stewart P.M. (Clin. Chem. 2003) 3 4 22 46 65
  3. Variability of AChE, BChE, and ChAT genes in the late-onset form of Alzheimer's disease and relationships with response to treatment with Donepezil and Rivastigmine. (PMID: 18780301) Scacchi R. … Corbo R.M. (Am. J. Med. Genet. B Neuropsychiatr. Genet. 2009) 3 22 46 65
  4. Progression from mild cognitive impairment to Alzheimer's disease: effects of sex, butyrylcholinesterase genotype, and rivastigmine treatment. (PMID: 19617863) Ferris S. … Lane R. (Pharmacogenet. Genomics 2009) 3 22 46 65
  5. Five new naturally occurring mutations of the BCHE gene and frequencies of 12 butyrylcholinesterase alleles in a Brazilian population. (PMID: 18300943) Mikami L.R. … Chautard-Freire-Maia E.A. (Pharmacogenet. Genomics 2008) 3 4 22 65

Products for BCHE Gene

Sources for BCHE Gene

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