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BCDIN3D Gene

protein-coding   GIFtS: 50
GCID: GC12M050231

BCDIN3 Domain Containing

  Search for BCDIN3D
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
BCDIN3 Domain Containing1 2
BCDIN3 Domain-Containing Protein2 3
Pre-MiRNA 5'-Monophosphate Methyltransferase2
Probable Methyltransferase BCDIN3D2
EC 2.1.1.-3
EC 2.1.18

External Ids:    HGNC: 270501   Entrez Gene: 1442332   Ensembl: ENSG000001866667   UniProtKB: Q7Z5W33   

Export aliases for BCDIN3D gene to outside databases

Previous GC identifers: GC12M048518 GC12M047260


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for BCDIN3D Gene:
BCDIN3D (BCDIN3 domain containing) is a protein-coding gene. GO annotations related to this gene include O-methyltransferase activity and RNA methyltransferase activity.

UniProtKB/Swiss-Prot: BN3D2_HUMAN, Q7Z5W3
Function: O-methyltransferase that specifically dimethylates the 5' monophosphate of pre-miRNAs, acting as a
negative regulator of miRNA processing. The 5' monophosphate of pre-miRNAs is recognized by DICER1 and is
required for pre-miRNAs processing: methylation at this position reduces the processing of pre-miRNAs by DICER1.
Able to mediate methylation of pre-miR-145, as well as other pre-miRNAs




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000012.11  NC_018923.2  NT_029419.13  
Regulatory elements:
   Regulatory transcription factor binding sites in the BCDIN3D gene promoter:
         Bach1   HOXA3   HTF   SREBP-1c   C/EBPalpha   GATA-1   SREBP-1b   SREBP-1a   IRF-7A   Msx-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidBCDIN3D promoter sequence
   Search Chromatin IP Primers for BCDIN3D

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat BCDIN3D


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 12q13.12   Ensembl cytogenetic band:  12q13.12   HGNC cytogenetic band: 12q13.13

BCDIN3D Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
BCDIN3D gene location

GeneLoc information about chromosome 12         GeneLoc Exon Structure

GeneLoc location for GC12M050231:  view genomic region     (about GC identifiers)

Start:
50,229,826 bp from pter      End:
50,236,912 bp from pter
Size:
7,087 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: BN3D2_HUMAN, Q7Z5W3 (See protein sequence)
Recommended Name: Pre-miRNA 5'-monophosphate methyltransferase  
Size: 292 amino acids; 33200 Da
Subunit: Interacts with DICER1; the interaction may be mediated by RNA
Secondary accessions: A8K829

Explore the universe of human proteins at neXtProt for BCDIN3D: NX_Q7Z5W3

Explore proteomics data for BCDIN3D at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys143
  • Modification sites at PhosphoSitePlus
  • 4 DME Specific Peptides for BCDIN3D (Q7Z5W3)
     WDRSLLLFR  ILTQDHGMEL  LSSFLSQFGRSVFD  YLLVEPQPWKCYRAAARRLRKLGLH 


    See BCDIN3D Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_859059.1  
    ENSEMBL proteins: 
     ENSP00000335201  

    BCDIN3D Human Recombinant Protein Products:

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    ProSpec Recombinant Protein for BCDIN3D
    Cloud-Clone Corp. Proteins for BCDIN3D

     
    Search eBioscience for Proteins for BCDIN3D 

    BCDIN3D Antibody Products:

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    BCDIN3D Assay Products:

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    Cloud-Clone Corp. ELISAs for BCDIN3D
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    Search eBioscience for ELISAs for BCDIN3D 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    2 InterPro protein domains:
     IPR010675 Bin3
     IPR024160 BIN3_SAM-bd_dom

    Graphical View of Domain Structure for InterPro Entry Q7Z5W3

    ProtoNet protein and cluster: Q7Z5W3

    UniProtKB/Swiss-Prot: BN3D2_HUMAN, Q7Z5W3
    Similarity: Belongs to the methyltransferase superfamily
    Similarity: Contains 1 Bin3-type SAM domain


    Find genes that share domains with BCDIN3D           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: BN3D2_HUMAN, Q7Z5W3
    Function: O-methyltransferase that specifically dimethylates the 5' monophosphate of pre-miRNAs, acting as a
    negative regulator of miRNA processing. The 5' monophosphate of pre-miRNAs is recognized by DICER1 and is
    required for pre-miRNAs processing: methylation at this position reduces the processing of pre-miRNAs by DICER1.
    Able to mediate methylation of pre-miR-145, as well as other pre-miRNAs

         Enzyme Numbers (IUBMB): EC 2.1.1.-1 EC 2.1.12

         Gene Ontology (GO): 3 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008168methyltransferase activity ----
    GO:0008171O-methyltransferase activity IDA--
    GO:0008173RNA methyltransferase activity IDA--
         
    Find genes that share ontologies with BCDIN3D           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for BCDIN3D:
     Decreased viability with pacli 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for BCDIN3D
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for BCDIN3D

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for BCDIN3D
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for BCDIN3D

    miRNA
    Products:
        
    miRTarBase miRNAs that target BCDIN3D:
    hsa-mir-877-3p (MIRT037166), hsa-mir-455-5p (MIRT040744)

    Block miRNA regulation of human, mouse, rat BCDIN3D using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate BCDIN3D (see all 18):
    hsa-miR-16-2* hsa-miR-19b-2* hsa-miR-4318 hsa-miR-3662 hsa-miR-761 hsa-miR-600 hsa-miR-516b hsa-miR-1237
    SwitchGear 3'UTR luciferase reporter plasmidBCDIN3D 3' UTR sequence
    Inhib. RNA
    Products:
        
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    Predesigned siRNA for gene silencing in human, mouse, rat BCDIN3D

    Gene Editing
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    Clone
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    GenScript: all cDNA clones in your preferred vector: BCDIN3D (NM_181708)
    Sino Biological Human cDNA Clone for BCDIN3D
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for BCDIN3D
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat BCDIN3D

    Cell Line
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    Browse ESI BIO Cell Lines and PureStem Progenitors for BCDIN3D 
    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for BCDIN3D


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    BN3D2_HUMAN, Q7Z5W3: Cytoplasm
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol2
    nucleus2
    extracellular1
    peroxisome1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA--
    GO:0005737cytoplasm IDA--

    Find genes that share ontologies with BCDIN3D           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for BCDIN3D
    Interactions:

        Search GeneGlobe Interaction Network for BCDIN3D

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    1 Interacting protein for BCDIN3D (ENSP000003352014) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ELAVL1ENSP000003852694STRING: ENSP00000385269
    About this table

    Gene Ontology (GO): 3 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001510RNA methylation IDA--
    GO:0010586miRNA metabolic process IDA--
    GO:2000632negative regulation of pre-miRNA processing IDA--

    Find genes that share ontologies with BCDIN3D           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for BCDIN3D (BN3D2)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for BCDIN3D gene: 
    NM_181708.2  

    Unigene Cluster for BCDIN3D:

    BCDIN3 domain containing
    Hs.142736  [show with all ESTs]
    Unigene Representative Sequence: NM_181708
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000333924(uc001rvh.3) ENST00000550861
    miRNA
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    Block miRNA regulation of human, mouse, rat BCDIN3D using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate BCDIN3D (see all 18):
    hsa-miR-16-2* hsa-miR-19b-2* hsa-miR-4318 hsa-miR-3662 hsa-miR-761 hsa-miR-600 hsa-miR-516b hsa-miR-1237
    SwitchGear 3'UTR luciferase reporter plasmidBCDIN3D 3' UTR sequence
    Inhib. RNA
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    OriGene RNAi products in human, mouse, rat for BCDIN3D
    Predesigned siRNA for gene silencing in human, mouse, rat BCDIN3D
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    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: BCDIN3D (NM_181708)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for BCDIN3D
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat BCDIN3D
    Primer
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    OriGene qSTAR qPCR primer pairs in human, mouse for BCDIN3D
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat BCDIN3D
      QuantiTect SYBR Green Assays in human, mouse, rat BCDIN3D
      QuantiFast Probe-based Assays in human, mouse, rat BCDIN3D

    Additional mRNA sequence: 

    AK292194.1 BC040957.1 BC053560.1 

    4 DOTS entries:

    DT.454294  DT.429621  DT.100833566  DT.99985301 

    Selected AceView cDNA sequences (see all 61):

    BM981620 BU178247 AI696181 BM468157 BE740503 CA307235 BM479941 AA306184 
    BC053560 NM_181708 BX116679 CD369547 AI634749 AL528547 AI269723 AA313452 
    BU188748 CR600896 AI094651 AW516322 CR612652 BC040957 AW665768 BF969454 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    BCDIN3D expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GAATTAATAT
    BCDIN3D Expression
    About this image


    BCDIN3D expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     
     Skeletal Muscle (Muscoskeletal System)    fully expand to see all 2 entries
             Mononuclear Myocytes Hyoid Arch Muscles
    BCDIN3D Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    BCDIN3D Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.142736
        Custom PCR Arrays for BCDIN3D
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for BCDIN3D

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for BCDIN3D gene from Selected species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Bcdin3d1 , 5 BCDIN3 domain containing1, 5 81.68(n)1
    80.14(a)1
      15 (56.13 cM)5
    752841  NM_029236.21  NP_083512.21 
     994700845 
    chicken
    (Gallus gallus)
    Aves BCDIN3D1 BCDIN3 domain containing 66.93(n)
    67.47(a)
      431303  XM_428854.4  XP_428854.4 
    lizard
    (Anolis carolinensis)
    Reptilia BCDIN3D6
    BCDIN3 domain containing
    62(a)
    1 ↔ 1
    2(96022644-96027277)
    African clawed frog
    (Xenopus laevis)
    Amphibia MGC691722 hypothetical protein MGC69172 73.3(n)    BC056133.1 
    zebrafish
    (Danio rerio)
    Actinopterygii LOC5683751 probable methyltransferase BCDIN3D-like 56.54(n)
    53.16(a)
      568375  XM_691701.4  XP_696793.3 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG113421 CG11342 46.42(n)
    38.36(a)
      38538  NM_139639.2  NP_647896.1 


    ENSEMBL Gene Tree for BCDIN3D (if available)
    TreeFam Gene Tree for BCDIN3D (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for BCDIN3D (see all 64)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 12 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs733109191,2
    C,F--50235474(+) GAGACT/CGTATC 1 -- int13Minor allele frequency- C:0.06WA CSA 122
    rs1409787361,2
    C--50235538(+) CCAAAA/GTCTCT 1 -- int10--------
    rs1159958381,2
    C,F--50235792(+) GTGCCG/ACCCTT 1 -- int12Minor allele frequency- A:0.05WA NA 238
    rs1147714101,2
    C,F--50235861(+) TCAACT/CCACTG 1 -- int11Minor allele frequency- C:0.03WA 118
    rs1448340521,2
    --50235978(+) CCTGCA/CTCAGC 1 -- int10--------
    rs1483950381,2
    C--50236168(+) CTCAC-/TCTTTT 1 -- int10--------
    rs1157321541,2
    F--50236184(+) ATAAAC/TATGCA 1 -- int11Minor allele frequency- T:0.03WA 118
    rs1831530941,2
    --50236209(+) TCCTGC/TACTGT 1 -- int10--------
    rs1867147451,2
    --50236217(+) TGTATA/GGCACA 1 -- int10--------
    rs111691751,2
    F,H--50236528(+) TATACT/CCGTTT 1 -- int15Minor allele frequency- C:0.04NS EA WA 536

    HapMap Linkage Disequilibrium report for BCDIN3D (50229826 - 50236912 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for BCDIN3D:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv522972CNV Gain19592680

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing BCDIN3D
    DNA2.0 Custom Variant and Variant Library Synthesis for BCDIN3D

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    Find genes that share disorders with BCDIN3D           About GenesLikeMe

    Genetic Association Database (GAD): BCDIN3D
    Human Genome Epidemiology (HuGE) Navigator: BCDIN3D (8 documents)

    Export disorders for BCDIN3D gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for BCDIN3D gene, integrated from 10 sources (see all 15):
    (articles sorted by number of sources associating them with BCDIN3D)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Human RNA methyltransferase BCDIN3D regulates microRNA processing. (PubMed id 23063121)1, 2 Xhemalce B.... Kouzarides T. (Cell 2012)
    2. Genetic susceptibility to obesity and related traits in childhood and adolescence: influence of loci identified by genome-wide association studies. (PubMed id 20724581)1, 4 den Hoed M....Loos R.J. (Diabetes 2010)
    3. Obesity and diabetes genes are associated with being born small for gestational age: results from the Auckland Birthweight Collaborative study. (PubMed id 20712903)1, 4 Morgan A.R....Mitchell E.A. (BMC Med. Genet. 2010)
    4. Implication of genetic variants near NEGR1, SEC16B, TMEM18, ETV5/DGKG, GNPDA2, LIN7C/BDNF, MTCH2, BCDIN3D/FAIM2, SH2B1, FTO, MC4R, and KCTD15 with obesity and type 2 diabetes in 7705 Chinese. (PubMed id 20215397)1, 4 Ng M.C....Ma R.C. (J. Clin. Endocrinol. Metab. 2010)
    5. Analyses of shared genetic factors between asthma and obesity in children. (PubMed id 20816195)1, 4 MelAcn E....Lasky-Su J. (J. Allergy Clin. Immunol. 2010)
    6. NRXN3 is a novel locus for waist circumference: a genome-wide association study from the CHARGE Consortium. (PubMed id 19557197)1, 4 Heard-Costa N.L....North K.E. (PLoS Genet. 2009)
    7. Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity. (PubMed id 19079260)1, 4 Thorleifsson G....Stefansson K. (Nat. Genet. 2009)
    8. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (amp 2011)
    9. Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. (PubMed id 20935630)4 Speliotes E.K....Loos R.J. (Nat. Genet. 2010)
    10. Dynamics of cullin-RING ubiquitin ligase network revealed by systematic quantitative proteomics. (PubMed id 21145461)1 Bennett E.J....Harper J.W. (Cell 2010)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 144233 HGNC: 27050 AceView: LOC144233 Ensembl:ENSG00000186666 euGenes: HUgn144233
    ECgene: BCDIN3D H-InvDB: BCDIN3D

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for BCDIN3D Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for BCDIN3D gene:
    Search GeneIP for patents involving BCDIN3D

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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